CN1169948C - 生物相容的支架的制备方法及由该方法制备的支架 - Google Patents

生物相容的支架的制备方法及由该方法制备的支架 Download PDF

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Publication number
CN1169948C
CN1169948C CNB001326376A CN00132637A CN1169948C CN 1169948 C CN1169948 C CN 1169948C CN B001326376 A CNB001326376 A CN B001326376A CN 00132637 A CN00132637 A CN 00132637A CN 1169948 C CN1169948 C CN 1169948C
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China
Prior art keywords
polymer
salt
scaffold
organic solvent
acid
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Expired - Fee Related
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CNB001326376A
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English (en)
Chinese (zh)
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CN1297042A (zh
Inventor
尹准镇
朴泰宽
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Inotec Pharmaceutical Co
Korea Advanced Institute of Science and Technology
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Enotec Pharmaceutical Co
Korea Advanced Institute of Science and Technology
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/0014—Use of organic additives
    • C08J9/0023—Use of organic additives containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2367/00—Characterised by the use of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Derivatives of such polymers
    • C08J2367/04—Polyesters derived from hydroxy carboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/06—Biodegradable
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
CNB001326376A 1999-11-16 2000-11-16 生物相容的支架的制备方法及由该方法制备的支架 Expired - Fee Related CN1169948C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR50922/1999 1999-11-16
KR10-1999-0050922A KR100372751B1 (ko) 1999-11-16 1999-11-16 생체조직공학용 다공성 생분해성 고분자 지지체의 제조방법

Publications (2)

Publication Number Publication Date
CN1297042A CN1297042A (zh) 2001-05-30
CN1169948C true CN1169948C (zh) 2004-10-06

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CNB001326376A Expired - Fee Related CN1169948C (zh) 1999-11-16 2000-11-16 生物相容的支架的制备方法及由该方法制备的支架

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KR (1) KR100372751B1 (enExample)
CN (1) CN1169948C (enExample)
AR (1) AR026510A1 (enExample)
AU (1) AU780321B2 (enExample)
BR (1) BR0005413B1 (enExample)
CA (1) CA2326057A1 (enExample)
HU (1) HUP0004498A3 (enExample)
IL (1) IL139715A (enExample)
NZ (1) NZ508148A (enExample)
SG (1) SG92758A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101147810B (zh) * 2007-11-01 2010-05-19 南昌大学第一附属医院 细胞-生物可降解材料复合物及其制备方法和应用

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101491703B (zh) * 2001-12-24 2013-02-20 财团法人工业技术研究院 体外组织的培养方法及其多孔隙载体
KR100629392B1 (ko) * 2002-05-10 2006-09-29 주식회사 리젠 바이오텍 스케폴드를 이용한 체외에서의 정자 배양방법
KR100499096B1 (ko) * 2002-09-13 2005-07-01 이진호 조직공학용 다공성 고분자 지지체의 제조방법
MX2007006833A (es) 2004-12-10 2007-10-08 Talima Therapeutics Inc Composiciones y metodos para tratar condiciones de la unidad de una.
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
CN100431622C (zh) * 2005-12-08 2008-11-12 东南大学 组织工程用聚合物多孔支架材料的方法及其制备装置
WO2007107038A1 (en) * 2006-03-20 2007-09-27 Hua Liu Constructing tumor model in vitro and its application
KR100760511B1 (ko) * 2006-11-16 2007-10-04 한국과학기술연구원 과산화수소를 이용한 조직공학용 다공성 생분해 고분자지지체의 제조 방법
KR100963435B1 (ko) 2008-06-19 2010-06-17 한국과학기술연구원 서방형 약물전달 및 조직재생용 덮인 다공성 생분해성고분자 미립구의 제조 방법
KR101003749B1 (ko) 2008-09-19 2010-12-23 문형순 폴리락타이드를 이용한 다공성 소재의 제조 방법
EP2787074A4 (en) * 2011-12-01 2015-08-12 Fujisoft Inc PROCESS FOR LONG-TERM STORAGE OF A POROUS BODY WITH CHONDROCYTES
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
CN106701570A (zh) * 2015-08-18 2017-05-24 重庆润泽医药有限公司 一种组织细胞培养装置
WO2017099261A1 (ko) * 2015-12-07 2017-06-15 주식회사 글로원 염침출 및 침지침강법을 이용한 스캐폴더 제조방법 및 그 스캐폴더
US12102973B2 (en) 2015-12-18 2024-10-01 Safeguard Biosystems Holdings Ltd. Three-dimensional polymer networks with channels situated therein
EP3418741A1 (en) * 2017-06-19 2018-12-26 Safeguard Biosystems Holdings Ltd. Three-dimensional polymer networks and their use
CN110947035B (zh) * 2019-10-30 2022-04-05 中山大学附属第六医院 一种p4hb补片表面多孔化改性的方法及p4hb补片
CN114958709B (zh) * 2021-12-07 2024-04-19 中科睿极(海宁)生物科技有限公司 可快速崩解的微载体聚集体及其制备方法
CN115645609A (zh) * 2021-12-30 2023-01-31 盐城工业职业技术学院 一种三维多孔生物可降解聚合物人工食管支架及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514378A (en) * 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
US5502092A (en) * 1994-02-18 1996-03-26 Minnesota Mining And Manufacturing Company Biocompatible porous matrix of bioabsorbable material
US5723508A (en) * 1996-01-25 1998-03-03 Northwestern University Method of fabricating emulsion freeze-dried scaffold bodies and resulting products
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US6165486A (en) * 1998-11-19 2000-12-26 Carnegie Mellon University Biocompatible compositions and methods of using same
US6586246B1 (en) * 1999-03-18 2003-07-01 Innotech Medical, Inc. Preparing porous biodegradable polymeric scaffolds for tissue engineering using effervescent salts
KR100288488B1 (ko) * 1999-03-18 2001-04-16 윤덕용 발포성 염을 이용한 생체조직공학용 다공성 고분자 지지체의 제조방법
US6103255A (en) * 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101147810B (zh) * 2007-11-01 2010-05-19 南昌大学第一附属医院 细胞-生物可降解材料复合物及其制备方法和应用

Also Published As

Publication number Publication date
SG92758A1 (en) 2002-11-19
IL139715A (en) 2006-06-11
AU780321B2 (en) 2005-03-17
CN1297042A (zh) 2001-05-30
HUP0004498A3 (en) 2003-10-28
AU7160000A (en) 2001-05-17
CA2326057A1 (en) 2001-05-16
KR20010046941A (ko) 2001-06-15
NZ508148A (en) 2002-05-31
BR0005413B1 (pt) 2012-08-07
KR100372751B1 (ko) 2003-02-17
HU0004498D0 (enExample) 2001-01-29
IL139715A0 (en) 2002-02-10
AR026510A1 (es) 2003-02-12
HUP0004498A2 (hu) 2001-10-28
BR0005413A (pt) 2001-08-07

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Owner name: KOREA ADVANCED INST. OF SCI. & TECH.; INOTEC MEDI

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