CN116474057B - Composition for improving respiratory tract immunity - Google Patents
Composition for improving respiratory tract immunity Download PDFInfo
- Publication number
- CN116474057B CN116474057B CN202310295063.3A CN202310295063A CN116474057B CN 116474057 B CN116474057 B CN 116474057B CN 202310295063 A CN202310295063 A CN 202310295063A CN 116474057 B CN116474057 B CN 116474057B
- Authority
- CN
- China
- Prior art keywords
- parts
- respiratory tract
- composition
- crude drug
- tract immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000002345 respiratory system Anatomy 0.000 title claims abstract description 75
- 230000036039 immunity Effects 0.000 title claims abstract description 74
- 239000000203 mixture Substances 0.000 title claims abstract description 63
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 10
- 244000163122 Curcuma domestica Species 0.000 claims abstract description 10
- 235000003392 Curcuma domestica Nutrition 0.000 claims abstract description 10
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract description 10
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract description 10
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract description 10
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract description 10
- 244000119298 Emblica officinalis Species 0.000 claims abstract description 10
- 235000015489 Emblica officinalis Nutrition 0.000 claims abstract description 10
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 10
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 10
- 244000062245 Hedychium flavescens Species 0.000 claims abstract description 10
- 241001018563 Nekemias grossedentata Species 0.000 claims abstract description 10
- 235000004347 Perilla Nutrition 0.000 claims abstract description 10
- 244000124853 Perilla frutescens Species 0.000 claims abstract description 10
- 244000203593 Piper nigrum Species 0.000 claims abstract description 10
- 235000008184 Piper nigrum Nutrition 0.000 claims abstract description 10
- 235000013614 black pepper Nutrition 0.000 claims abstract description 10
- 235000003373 curcuma longa Nutrition 0.000 claims abstract description 10
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims abstract description 10
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 10
- 235000011477 liquorice Nutrition 0.000 claims abstract description 10
- 235000013976 turmeric Nutrition 0.000 claims abstract description 10
- 244000246386 Mentha pulegium Species 0.000 claims abstract description 3
- 235000016257 Mentha pulegium Nutrition 0.000 claims abstract description 3
- 235000004357 Mentha x piperita Nutrition 0.000 claims abstract description 3
- 235000001050 hortel pimenta Nutrition 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 74
- 229940079593 drug Drugs 0.000 claims description 69
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 41
- 239000000284 extract Substances 0.000 claims description 40
- 239000002245 particle Substances 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 16
- 238000002156 mixing Methods 0.000 claims description 15
- 239000006286 aqueous extract Substances 0.000 claims 4
- 208000024891 symptom Diseases 0.000 abstract description 14
- 206010011224 Cough Diseases 0.000 abstract description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 9
- 206010036790 Productive cough Diseases 0.000 abstract description 8
- 208000032140 Sleepiness Diseases 0.000 abstract description 8
- 206010041349 Somnolence Diseases 0.000 abstract description 8
- 208000035475 disorder Diseases 0.000 abstract description 8
- 208000036626 Mental retardation Diseases 0.000 abstract description 7
- 208000006083 Hypokinesia Diseases 0.000 abstract description 6
- 230000000694 effects Effects 0.000 description 13
- 238000007873 sieving Methods 0.000 description 10
- 235000006679 Mentha X verticillata Nutrition 0.000 description 7
- 235000002899 Mentha suaveolens Nutrition 0.000 description 7
- 235000001636 Mentha x rotundifolia Nutrition 0.000 description 7
- 206010062717 Increased upper airway secretion Diseases 0.000 description 6
- 208000026435 phlegm Diseases 0.000 description 6
- 239000002994 raw material Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 5
- 238000004806 packaging method and process Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 244000269722 Thea sinensis Species 0.000 description 4
- 238000013329 compounding Methods 0.000 description 4
- 230000006866 deterioration Effects 0.000 description 4
- 235000013305 food Nutrition 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 201000007100 Pharyngitis Diseases 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 210000004556 brain Anatomy 0.000 description 3
- 239000000706 filtrate Substances 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 208000013220 shortness of breath Diseases 0.000 description 3
- 206010028748 Nasal obstruction Diseases 0.000 description 2
- 206010068319 Oropharyngeal pain Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 206010038687 Respiratory distress Diseases 0.000 description 2
- 244000185386 Thladiantha grosvenorii Species 0.000 description 2
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 description 2
- 230000033228 biological regulation Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000008451 emotion Effects 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000008187 granular material Substances 0.000 description 2
- 230000000521 hyperimmunizing effect Effects 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000010791 quenching Methods 0.000 description 2
- 230000037321 sleepiness Effects 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 238000007619 statistical method Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 229940126673 western medicines Drugs 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010012374 Depressed mood Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 206010057190 Respiratory tract infections Diseases 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010044302 Tracheitis Diseases 0.000 description 1
- 206010046306 Upper respiratory tract infection Diseases 0.000 description 1
- 206010000059 abdominal discomfort Diseases 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 230000002354 daily effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 238000012418 validation experiment Methods 0.000 description 1
- 238000003809 water extraction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/67—Piperaceae (Pepper family), e.g. Jamaican pepper or kava
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pulmonology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composition for improving respiratory tract immunity, which is prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaf, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of Yunnan yellow ginger, 12-48 parts of turmeric and 20-80 parts of black pepper. The composition for improving respiratory tract immunity can improve symptoms such as cough, expectoration, hypodynamia, somnolence, mental retardation and the like caused by respiratory tract immunity and disorder thereof.
Description
Technical Field
The invention relates to a composition for improving respiratory tract immunity.
Background
At present, people deeply recognize the importance of daily self-health management, and especially recognize the long-term significance of good respiratory tract immunity to health and life.
The current major cause of respiratory tract immune disorders (either hyperimmune or hyperimmune) is a deterioration of the physiological environment. The deterioration of the external environment leads to the enhancement of respiratory tract sensitivity, so that various respiratory tract diseases such as tracheitis, bronchitis, pneumonia, pharyngitis, tonsillitis, upper respiratory tract infection, anaphylaxis and the like are easily obtained, and the long-term repeated attack of the diseases finally leads to the pulmonary immunity disorder. The clinical treatment mainly depends on drug treatment, and comprises western medicines and traditional Chinese medicines, and the traditional Chinese medicines have obvious advantages in improving immunity. At present, no edible composition product for improving respiratory tract immunity based on a traditional Chinese medicine formula is seen in the market.
Based on the above, there is an urgent need to develop a composition based on a menstruation prescription, which improves respiratory tract immunity, can regulate the human body by returning to channels, avoids the defects of large side effects, easy repetition of illness state and the like of western medicines, and has food-grade safety.
Disclosure of Invention
The invention aims to overcome the defects of the prior art, and provides a composition for improving respiratory tract immunity, which is prepared by selecting medicines or extracts thereof with homology of medicine and food and capability of improving respiratory tract immunity for combination and compounding, can comprehensively improve symptoms such as cough, expectoration, hypodynamia, somnolence, mental retardation and the like caused by the respiratory tract immunity and disorder of the human body through multi-channel conditioning, and has the advantages that all components meet the requirements of food regulations and the safety.
The technical scheme for achieving the purpose is as follows: a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaf, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of Yunnan yellow ginger, 12-48 parts of turmeric and 20-80 parts of black pepper.
The composition for improving the respiratory tract immunity adopts crude drug decoction pieces, crude drug decoction piece crushed particles, crude drug decoction piece water extract, crude drug decoction piece superfine powder or crude drug decoction piece alcohol extract as each component.
The composition for improving the respiratory tract immunity is a mixed water extract obtained by mixing crude drug decoction pieces of all components and then extracting with water.
In the above composition for improving respiratory tract immunity, each component of a part of components in the composition for improving respiratory tract immunity adopts a single crude drug decoction piece water extract, the crude drug decoction pieces of the rest components are mixed and then subjected to water extraction to obtain a part of mixed water extract, and then all the single crude drug decoction piece water extract and the part of mixed water extract are mixed to obtain the composition for improving respiratory tract immunity.
The composition for improving the respiratory tract immunity comprises a part of components of crude drug decoction piece crushed particles or crude drug decoction piece superfine powder, and the rest of components of the composition are crude drug decoction piece water extracts.
The composition for improving the respiratory tract immunity selects medicinal and edible flavors or extracts thereof which are homologous and have the effect of improving the respiratory tract immunity, and the honeysuckle, the dried orange peel, the liquorice and the phyllanthus emblica in the composition have the effects of clearing heat and detoxicating, eliminating dampness and resolving phlegm, tonifying spleen and stomach, promoting the production of body fluid to quench thirst, and is matched with the ampelopsis grossedentata leaves, the perilla seeds, the mint, the small yellow ginger in Yunnan, the Chinese yam, the momordica grosvenori and the like with the effects of promoting diuresis, resolving phlegm and relieving cough, eliminating phlegm and relieving sore throat, tonifying lung qi and the like. In addition, turmeric and black pepper which have auxiliary improving effect on symptoms caused by respiratory tract immunity disorder are added into the composition, so that the effect of improving respiratory tract immunity is comprehensively achieved.
Detailed Description
In order to enable those skilled in the art to better understand the technical solution of the present invention, the following detailed description is provided for specific embodiments thereof:
example 1:
a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
In this embodiment, each component of the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles, and the specific preparation method is as follows: crushing the components in the form of crude drug decoction pieces respectively, sieving with 20 mesh sieve, mixing, and packaging into tea bag to obtain the composition for improving respiratory tract immunity.
Example 2:
a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 75 parts of honeysuckle, 25 parts of dried orange peel, 20 parts of phyllanthus emblica, 20 parts of liquorice, 15 parts of Chinese yam, 15 parts of mint, 15 parts of ampelopsis grossedentata leaves, 7 parts of perilla seed, 7 parts of fructus momordicae, 2 parts of yellow ginger in Yunnan province, 18 parts of turmeric and 35 parts of black pepper.
In this embodiment, each component of the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles, and the specific preparation method is as follows: crushing the components in the form of crude drug decoction pieces respectively, sieving with 20 mesh sieve, mixing, and packaging into tea bag to obtain the composition for improving respiratory tract immunity.
Example 3:
a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 50 parts of honeysuckle, 20 parts of dried orange peel, 10 parts of phyllanthus emblica, 10 parts of liquorice, 10 parts of Chinese yam, 10 parts of mint, 10 parts of ampelopsis grossedentata leaves, 5 parts of perilla seed, 5 parts of fructus momordicae, 1 part of yellow ginger in Yunnan province, 12 parts of turmeric and 20 parts of black pepper.
In this embodiment, each component of the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles, and the specific preparation method is as follows: crushing the components in the form of crude drug decoction pieces respectively, sieving with 20 mesh sieve, mixing, and packaging into tea bag to obtain the composition for improving respiratory tract immunity.
Example 4:
a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 150 parts of honeysuckle, 80 parts of dried orange peel, 50 parts of phyllanthus emblica, 50 parts of liquorice, 30 parts of Chinese yam, 30 parts of mint, 30 parts of ampelopsis grossedentata leaves, 15 parts of perilla seed, 15 parts of fructus momordicae, 5 parts of yellow ginger in Yunnan province, 48 parts of turmeric and 80 parts of black pepper.
In this embodiment, each component of the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles, and the specific preparation method is as follows: crushing the components in the form of crude drug decoction pieces respectively, sieving with 20 mesh sieve, mixing, and packaging into tea bag to obtain the composition for improving respiratory tract immunity.
Example 5:
a composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
In this example, the crude drug decoction pieces water extract is used as each component of the composition for improving respiratory tract immunity.
The preparation method comprises the following steps: the water extract of each component is crushed and sieved, and the fine powder under 60 meshes of sieve and 180 parts of fine powder under the same sieve are taken and mixed uniformly. Adding 80% alcohol as binder into the mixed fine powder, granulating to obtain 60 mesh granule, drying at 50deg.C for 60 min, and packaging to obtain the final product.
The composition for improving respiratory tract immunity in the form of the water extract can be prepared by mixing and extracting, or prepared by compounding a single raw material extract, or prepared by mixing and extracting part of raw materials and compounding other single raw material extracts.
Compositions for improving respiratory tract immunity come in a variety of raw material forms, such as:
(1) The composition for improving respiratory tract immunity can be crude drug decoction pieces, crude drug decoction piece crushed particles, crude drug decoction piece water extract, crude drug decoction piece superfine powder or crude drug decoction piece ethanol extract.
(2) The composition for improving respiratory tract immunity is a mixed water extract obtained by mixing crude drug decoction pieces of each component and extracting with water.
(3) The composition for improving the respiratory tract immunity is prepared by mixing a part of components in a composition for improving the respiratory tract immunity with a single crude drug decoction piece water extract, mixing crude drug decoction pieces of the rest components, extracting with water to obtain a part of mixed water extract, and mixing all the single crude drug decoction piece water extract and the part of mixed water extract.
(4) A part of components in the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles or crude drug decoction piece superfine powder, and the rest components adopt crude drug decoction piece water extract.
The single crude drug decoction piece water extract can be prepared by the following steps: extracting single components in the form of crude drug decoction pieces in the composition for improving respiratory tract immunity with water at 50-70 ℃ for 1-2 hours, concentrating the extracting solution in vacuum at low temperature, freeze-drying the concentrated solution to obtain water extract coarse powder, and sieving the water extract coarse powder by a granulator to obtain single crude drug decoction piece water extract, wherein the particle proportion between 10-60 meshes in the single crude drug decoction piece water extract is more than 60%.
The mixed water extract and a part of the mixed water extract can be prepared by the following process: crude drug decoction pieces of all or part of components in the composition for improving respiratory tract immunity are filtered by a sieve with 150-300 meshes after being heated and refluxed for 1.5-3 hours by adding 10-15 times of water after being uniformly mixed without being smashed or smashed by a standard sieve with 3-5 meshes, all the filtrates are combined, the filtrate is concentrated to 1/5-1/10 of the volume of the original filtrate under the conditions of 50-70 ℃ and the vacuum degree of 70-100 mbar, and then the concentrated solution is freeze-dried to obtain the mixed water extract.
The crude drug decoction piece crushing granule can be prepared by the following process: pulverizing single component in crude drug decoction pieces in the composition for improving respiratory tract immunity at low rotation speed, sieving the pulverized material, and sieving with 10 mesh and 60 mesh sieve for secondary sieving; the large-particle materials which cannot pass through 10 meshes continue to be crushed at a low rotating speed, pass through a 10-mesh sieve and a 60-mesh sieve again for secondary screening, and reject under 60 meshes, and the particles between 10 and 60 meshes are taken to obtain the crushed granular raw materials with single components, so that the proportion of the particles between 10 and 60 meshes in the crushed granular raw materials with single components is more than 60 percent.
The crude drug decoction piece superfine powder can be prepared by the following process: vacuum freeze drying the single component in the form of crude drug decoction pieces in the composition for improving respiratory tract immunity, controlling the water content of the crude drug decoction pieces to be 3-5%, sieving with a 300-mesh sieve after low-temperature superfine wall breaking and crushing, continuously carrying out low-temperature superfine wall breaking and crushing treatment on particles which cannot pass 300 meshes, sieving with a 300-mesh sieve again, and combining all fine powder passing through the 300-mesh sieve to obtain the crude drug decoction piece superfine powder of the single component.
Efficacy validation experiment of the composition for improving respiratory tract immunity:
through the test of 10 persons in 4 days, the medicine has the tendency of improving 10 symptoms of cough, hypodynamia, mental retardation, slow brain reaction, asthma or shortness of breath, somnolence, taste/smell decline, expectoration, nasal obstruction/running nose and low emotion, and particularly has obvious improvement in the aspects of symptoms of cough, expectoration, hypodynamia, somnolence, mental retardation and the like.
The specific test process of human body test clothes is as follows:
the testers of the intervention group select 10 people infected with new post-coronary respiratory tract discomfort to test the composition for improving respiratory tract immunity, continuously test for 4 days, score each person according to symptom improvement condition every day, and then carry out statistical analysis according to the score to evaluate the effectiveness of the product formula.
Meanwhile, a control group is set, 10 persons infected with new post-coronary respiratory tract discomfort are selected from the control group, the composition for improving respiratory tract immunity is not taken, scoring is carried out according to the symptoms of each person every day, and then statistical analysis is carried out according to the scoring.
1. Product morphology: the respiratory tract immunity improving composition in the form of a teabag (3.8 g/bag) of example 1;
2. the administration method comprises the following steps: each person takes the medicine 2 times a day, 1 bag each time, and the medicine is taken after being brewed for 5 minutes by boiled water;
3. the panelist of the intervention group: 10 patients with new post-coronal respiratory distress;
4. personnel of the control group: 10 patients with new post-coronal respiratory distress;
5. scoring indexes: 16 indices-cough, asthma or shortness of breath, expectoration, debilitation, somnolence, stuffy nose/runny nose, mental retardation, insomnia, gastrointestinal discomfort, taste and smell deterioration, chest pain caused by cough, low emotion, occasional dizziness, arthralgia, occasional palpitation, and slow brain bag reaction-each index was set for 1-5 minutes, and a smaller score indicates a more alleviation of symptoms.
6. The statistics of the improvement of symptoms caused by respiratory tract immunity disorder in the intervention group are shown in table 1:
table 1:
in table 1, the values are expressed as mean±standard deviation (mean±sem); * Represent vs.0Days (compare to day 0 data), P <0.05; * Represent vs.0days (compare to day 0 data), P <0.01; * vs.0Days (compare to day 0 data), P <0.001.
7. The statistics of the symptoms caused by the airway immunity disorder of the control group are shown in Table 2:
table 2:
in table 2, the values are expressed as mean±standard deviation (mean±sem); # represents vs.1Days (compared to day 1), P <0.05.
Compared with the data in tables 1 and 2, the composition for improving respiratory tract immunity of the present invention is administered, and has a remarkable improving effect on 10 symptoms such as cough, hypodynamia, mental retardation, slow reaction of the brain bag, asthma or shortness of breath, sleepiness, taste/smell deterioration, expectoration, nasal obstruction/running nose and depressed mood, especially on the symptoms such as cough, expectoration, hypodynamia, sleepiness, mental retardation and the like.
The composition for improving the respiratory tract immunity selects medicinal and edible flavors or extracts thereof which are homologous and have the effect of improving the respiratory tract immunity, and the honeysuckle, the dried orange peel, the liquorice and the phyllanthus emblica in the composition have the effects of clearing heat and detoxicating, eliminating dampness and resolving phlegm, tonifying spleen and stomach, promoting the production of body fluid to quench thirst, and is matched with the ampelopsis grossedentata leaves, the perilla seeds, the mint, the small yellow ginger in Yunnan, the Chinese yam, the momordica grosvenori and the like with the effects of promoting diuresis, resolving phlegm and relieving cough, eliminating phlegm and relieving sore throat, tonifying lung qi and the like. In addition, turmeric and black pepper which have auxiliary improving effect on symptoms caused by respiratory tract immunity disorder are added into the composition, so that the effect of improving respiratory tract immunity is comprehensively achieved.
In the composition for improving respiratory tract immunity, each component can be crude drug decoction pieces, crude drug decoction piece crushed particles, crude drug decoction piece water extract, crude drug decoction piece superfine powder or crude drug decoction piece alcohol extract. Or mixing crude drug decoction pieces of each component, and extracting with water to obtain mixed water extract. Or part of the components adopts crude drug decoction piece crushed particles or crude drug decoction piece superfine powder, and the rest components adopt crude drug decoction piece water extract.
In conclusion, the composition for improving respiratory tract immunity disclosed by the invention is prepared by selecting medicines or extracts thereof which are homologous to medicines and foods and have the effect of improving respiratory tract immunity, and combining and compounding the medicines or extracts thereof, so that the symptoms of cough, expectoration, debilitation, somnolence, mental inadequacy and the like caused by the respiratory tract immunity and the disorder of the human body can be comprehensively improved through the conditioning of multiple channels of the human body, and all the components meet the requirements of food regulations and have safety.
It will be appreciated by persons skilled in the art that the above embodiments are provided for illustration only and not for limitation of the invention, and that variations and modifications of the above described embodiments are intended to fall within the scope of the claims of the invention as long as they fall within the true spirit of the invention.
Claims (5)
1. The composition for improving the respiratory tract immunity is characterized by being prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaves, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of yellow ginger from Yunnan, 12-48 parts of turmeric and 20-80 parts of black pepper.
2. The composition for improving respiratory tract immunity according to claim 1, wherein each component in the composition for improving respiratory tract immunity adopts crude drug decoction pieces, crude drug decoction piece crushed particles, crude drug decoction piece water extract or crude drug decoction piece superfine powder.
3. The composition for improving respiratory tract immunity according to claim 1, wherein the composition for improving respiratory tract immunity is a mixed water extract obtained by mixing crude drug decoction pieces of each component and extracting with water.
4. The composition for improving respiratory tract immunity according to claim 1, wherein each of a part of the components in the composition for improving respiratory tract immunity is prepared by mixing a single crude drug decoction piece aqueous extract, and a part of the mixed aqueous extract obtained by extracting the crude drug decoction pieces of the remaining components with water, and then mixing all of the single crude drug decoction piece aqueous extract and the part of the mixed aqueous extract.
5. The composition for improving respiratory tract immunity according to claim 1, wherein a part of the components in the composition for improving respiratory tract immunity adopts crude drug decoction piece crushed particles or crude drug decoction piece superfine powder, and the rest components adopt crude drug decoction piece water extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310295063.3A CN116474057B (en) | 2023-03-24 | 2023-03-24 | Composition for improving respiratory tract immunity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202310295063.3A CN116474057B (en) | 2023-03-24 | 2023-03-24 | Composition for improving respiratory tract immunity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN116474057A CN116474057A (en) | 2023-07-25 |
| CN116474057B true CN116474057B (en) | 2024-03-15 |
Family
ID=87216169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202310295063.3A Active CN116474057B (en) | 2023-03-24 | 2023-03-24 | Composition for improving respiratory tract immunity |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116474057B (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731556A (en) * | 2008-11-13 | 2010-06-16 | 龟甲万(新加坡)研发实验室私人有限公司 | Liquid reinforced flavouring for foodstuff and its preparing method |
| CN102166280A (en) * | 2011-04-14 | 2011-08-31 | 陕西省中医药研究院汉唐制药有限公司 | Chinese medicinal composition for preventing and treating common cold and influenza and preparation method thereof |
-
2023
- 2023-03-24 CN CN202310295063.3A patent/CN116474057B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101731556A (en) * | 2008-11-13 | 2010-06-16 | 龟甲万(新加坡)研发实验室私人有限公司 | Liquid reinforced flavouring for foodstuff and its preparing method |
| CN102166280A (en) * | 2011-04-14 | 2011-08-31 | 陕西省中医药研究院汉唐制药有限公司 | Chinese medicinal composition for preventing and treating common cold and influenza and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116474057A (en) | 2023-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103720903B (en) | A kind of anti-inflammatory clearing lung-heat liver-protecting tea and preparation method thereof | |
| CN102640830B (en) | Chinese herbal medicine health care cold tea | |
| CN102613360B (en) | Honeysuckle health-care tea | |
| CN101129790A (en) | Compound hippophae rhamnoides lozenge method of producing the same | |
| CN116616395A (en) | Plant solid beverage for improving respiratory tract immunity and preparation process thereof | |
| CN109663021A (en) | Composition, preparation method and application with anti-oxidation function | |
| CN106389587A (en) | Clearing and moistening health care scented tea and preparation process thereof | |
| CN116474057B (en) | Composition for improving respiratory tract immunity | |
| CN107173660A (en) | A kind of health solid beverage for nursing one's health damp-heat constitution and preparation method thereof | |
| CN109464540B (en) | Spray for relieving discomfort of oral cavity and throat and preparation method thereof | |
| CN111743968A (en) | Plant composition, preparation method and application thereof | |
| CN109793862A (en) | A kind of mulberry leaf-chrysanthemum composition and preparation method thereof | |
| CN107456495A (en) | It is a kind of be used to coughing, abundant expectoration, the composition granule and preparation method thereof of asthma | |
| CN116474056A (en) | Plant honey essence for improving respiratory tract immunity and preparation process thereof | |
| CN110179931B (en) | Heart-nourishing and nerve-soothing composition and preparation method thereof | |
| CN116369404A (en) | Health tea for improving respiratory tract immunity and preparation process thereof | |
| CN109481497B (en) | Buccal tablet for relieving discomfort of oral cavity and throat and preparation method thereof | |
| CN106474330A (en) | A kind of tranquillizing and allaying excitement alternative tea made as composition using food plant | |
| CN106616123A (en) | Health drink and making method thereof | |
| CN116439334A (en) | Plant concentrated drink for improving respiratory tract immunity and preparation process thereof | |
| CN114681568A (en) | Cough-relieving and phlegm-reducing composition, substitute tea, candy and preparation method | |
| CN111567801A (en) | Spina date seed and royal jelly tablet and preparation process thereof | |
| CN116473179A (en) | Plant beverage for improving respiratory tract immunity and preparation process thereof | |
| CN116492437B (en) | Plant buccal tablet for improving respiratory tract immunity and preparation process thereof | |
| CN103652201A (en) | Olive healthy tea and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |