CN116474056A - Plant honey essence for improving respiratory tract immunity and preparation process thereof - Google Patents

Plant honey essence for improving respiratory tract immunity and preparation process thereof Download PDF

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Publication number
CN116474056A
CN116474056A CN202310295061.4A CN202310295061A CN116474056A CN 116474056 A CN116474056 A CN 116474056A CN 202310295061 A CN202310295061 A CN 202310295061A CN 116474056 A CN116474056 A CN 116474056A
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Prior art keywords
respiratory tract
parts
honey
improving
composition
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Inventor
孙武兴
李俊宇
史珅
缪着
王飞飞
马骁
郭振宇
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Yunnan Yunke Characteristic Plant Extraction Laboratory Co ltd
Yunnan Beitani Biotechnology Group Co ltd
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Yunnan Yunke Characteristic Plant Extraction Laboratory Co ltd
Yunnan Beitani Biotechnology Group Co ltd
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Priority to CN202310295061.4A priority Critical patent/CN116474056A/en
Publication of CN116474056A publication Critical patent/CN116474056A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/42Cucurbitaceae (Cucumber family)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/75Rutaceae (Rue family)
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    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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Abstract

The invention discloses plant honey essence for improving respiratory tract immunity, which consists of a composition for improving respiratory tract immunity with the mass fraction of 10-30% and honey with the mass fraction of 70-90%, wherein the composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaf, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of Yunnan yellow ginger, 12-48 parts of turmeric and 20-80 parts of black pepper. Can comprehensively improve symptoms such as cough, expectoration, debilitation, somnolence, mental inadequacy and the like caused by respiratory tract immunity and disorder thereof. The invention also discloses a preparation process of the plant honey essence for improving the respiratory tract immunity, which is simple to operate, adopts ultrahigh temperature instantaneous sterilization or pasteurization, effectively retains active substances, has no additive in the product, and has high product purity.

Description

Plant honey essence for improving respiratory tract immunity and preparation process thereof
Technical Field
The invention relates to plant honey essence for improving respiratory tract immunity and a preparation process thereof.
Background
At present, people deeply recognize the importance of daily self-health management, and especially recognize the long-term significance of good respiratory tract immunity to health and life.
The current major cause of respiratory tract immune disorders (either hyperimmune or hyperimmune) is a deterioration of the physiological environment. The deterioration of the external environment leads to the enhancement of respiratory tract sensitivity, so that various respiratory tract diseases such as tracheitis, bronchitis, pneumonia, pharyngitis, tonsillitis, upper respiratory tract infection, anaphylaxis and the like are easily obtained, and the long-term repeated attack of the diseases finally leads to the pulmonary immunity disorder. The clinical treatment mainly depends on drug treatment, and comprises western medicines and traditional Chinese medicines, and the traditional Chinese medicines have obvious advantages in improving immunity. At present, no edible honey essence product for improving the immunity of the respiratory tract is seen in the market.
At present, the production process of the honey essence product is complicated in multiple steps, and the solvent (water) is added in the processing process, so that the content of honey essence traditional Chinese medicinal materials and the effective components are reduced, for example, chinese patent CN1173342 discloses fleece-flower root honey essence and the production process thereof, and mainly relates to a health-care oral liquid, namely, fleece-flower root honey essence and the production process thereof, wherein royal jelly, prepared fleece-flower root, mulberry juice and honey are added to prepare the oral liquid.
Disclosure of Invention
The invention aims to overcome the defects of the prior art, provides plant honey essence for improving respiratory tract immunity, selects medicinal and edible medicaments or extracts thereof which have the effect of improving respiratory tract immunity to be combined and compounded, can comprehensively improve symptoms such as cough, expectoration, hypodynamia, somnolence, mental inadequacy and the like caused by the respiratory tract immunity and the disorder of the human body through the conditioning of multiple channels of the human body, and all components meet the requirements of food regulations and have safety.
The invention also aims to provide a preparation process of plant honey essence for improving respiratory tract immunity, which is simple to operate, adopts ultra-high temperature instantaneous sterilization or pasteurization, effectively retains active substances of the composition for improving respiratory tract immunity, has the functions of tonifying middle-jiao and moistening dryness, and simultaneously can bring different sweet mouthfeel by using different types of honey, has no additive addition in products, has high product purity, and is a product suitable for the old and the young.
The technical scheme for achieving the purpose is as follows: the plant honey essence for improving the respiratory tract immunity consists of 10-30% of a composition for improving the respiratory tract immunity and 70-90% of honey, wherein the composition for improving the respiratory tract immunity is prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaf, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of Yunnan yellow ginger, 12-48 parts of turmeric and 20-80 parts of black pepper.
The plant honey essence for improving respiratory tract immunity, wherein the honey is solid honey and/or liquid honey.
The plant honey essence for improving respiratory tract immunity is prepared from at least one of Tibetan honey, snow honey, shanglira winter honey, loquat honey, wild dam seed honey, crystallized soil honey and Sichuan style fruit honey.
The plant honey essence for improving the respiratory tract immunity, wherein each component in the composition for improving the respiratory tract immunity adopts crude drug decoction piece water extract or crude drug decoction piece superfine powder, or part of components in the composition for improving the respiratory tract immunity adopts crude drug decoction piece superfine powder, and the rest components adopt crude drug decoction piece water extract.
The invention also provides a preparation process of the plant honey essence for improving the respiratory tract immunity, which comprises the following steps:
s1, preparing a composition for improving respiratory tract immunity, which comprises the following steps: the composition for improving the respiratory tract immunity is prepared by adopting an aqueous extract extraction process and/or an ultrafine powder process;
s2, honey treatment: the honey is used for decrystallization when being solid honey, and the honey is used for decrystallization when being liquid honey;
s3, adding the honey processed in the step S2 with the mass fraction of 70-90% into stirring equipment, and stirring and uniformly mixing for 10-20 min;
s4, taking the composition for improving the respiratory tract immunity prepared in the step S1 with the mass fraction of 10-30%, adding the composition into the stirring equipment for multiple times, and uniformly stirring the composition with the honey in the stirring equipment for 10-20 min;
s5, a sterilization step: adopts ultra-high temperature instantaneous sterilization or pasteurization;
s6, discharging to obtain the plant honey essence product for improving respiratory tract immunity.
In the preparation process of the plant nectar for improving the respiratory tract immunity, in the step S1, the specific steps of preparing the composition for improving the respiratory tract immunity by adopting an aqueous extract extraction process are as follows: the method for improving respiratory tract immunity comprises the steps of weighing crude drug decoction pieces of each component according to the formula of the composition for improving respiratory tract immunity according to claim 1, sieving the crude drug decoction pieces with a standard sieve of 3-5 meshes after mashing or mashing, adding 10-15 times of water by volume after uniform mixing, heating and refluxing for 1.5-3 hours at 90-100 ℃, filtering the obtained extract by using a sieve of 150-300 meshes, repeatedly heating and extracting for 1-3 times, filtering, merging all filtrate, concentrating the filtrate under vacuum at the temperature of 50-70 ℃ and the vacuum degree of 70-100 mbar to 1/5-1/10 of the original filtrate volume, and then freeze-drying the concentrated solution to obtain the composition for improving respiratory tract immunity.
In the preparation process of the plant nectar for improving the respiratory tract immunity, in the step S1, the specific steps of preparing the composition for improving the respiratory tract immunity by adopting an ultrafine powder process are as follows: the method for preparing the composition for improving respiratory tract immunity according to claim 1 comprises weighing crude drug decoction pieces of each component, placing into a traditional Chinese medicine powder grinding machine for preliminary grinding, sieving with No. 4 sieve or No. 5 sieve, and pulverizing with an ultra-micro pulverizer to obtain the composition for improving respiratory tract immunity.
In the preparation process of the plant honey essence for improving the respiratory tract immunity, in the step S1, the composition for improving the respiratory tract immunity is prepared by adopting an aqueous extract extraction process and an ultrafine powder process, and the preparation process comprises the following specific steps of:
A. weighing crude drug decoction pieces of each component according to the formula of the composition for improving respiratory tract immunity as claimed in claim 1;
B. placing crude drug decoction pieces of a part of the components in a traditional Chinese medicine powder grinding machine for preliminary grinding, passing through a No. 4 sieve or a No. 5 sieve, and then grinding by an ultrafine grinder to obtain ultrafine powder for later use;
C. the crude drug decoction pieces of the rest components are not required to be smashed or smashed and then pass through a standard sieve with 3 meshes to 5 meshes, water with 10 to 15 times of volume is added after the mixture is evenly mixed, heating reflux is carried out for 1.5 to 3 hours at the temperature of 90 to 100 ℃, the obtained extract is filtered by a sieve with 150 meshes to 300 meshes, heating extraction is repeated for 1 to 3 times and filtering, all the filtrates are combined, vacuum concentration is carried out to 1/5 to 1/10 of the volume of the original filtrate under the conditions of the temperature of 50 to 70 ℃ and the vacuum degree of 70 to 100mbar, and then the concentrated liquid is freeze-dried to obtain freeze-dried powder of the water extract for standby;
D. and then mixing the superfine powder obtained in the step B and the water extract freeze-dried powder obtained in the step C, and then placing the mixture in a superfine pulverizer to pulverize so as to obtain the composition for improving the respiratory tract immunity.
The preparation process of the plant honey essence for improving respiratory tract immunity comprises the steps of rotating the superfine pulverizer at 300-400 rpm, pulverizing for 20-40 min, and mixing the materials according to a ball-to-material ratio of 1 (5-20): and mixing the materials according to a ball-to-ball ratio of 1 (1-6).
The plant honey essence for improving the respiratory tract immunity and the technical scheme of the preparation process thereof have the following beneficial effects:
(1) The plant honey is carefully selected, has the same medicinal and edible taste and has the effect of improving the respiratory tract immunity or the extract thereof, is combined and compounded, can regulate the multiple channels of a human body, comprehensively improve the symptoms of cough, expectoration, hypodynamia, somnolence, mental inequality and the like caused by the respiratory tract immunity and the disorder thereof, and has the advantages that all the components meet the requirements of food regulations and the safety;
(2) Fills the blank of the preparation process of the honey essence of the formula for improving the immunity of the respiratory tract;
(3) At present, in dosage forms related to honey essence, fewer products are used for improving respiratory tract immunity, and the prescription for improving respiratory tract immunity realizes innovation on the dosage forms;
(4) The honey essence has high purity, no water is added in the process, and the finished product has the characteristic of fragrant and sweet taste according to the types of different nectar used in the preparation process;
(5) The honey essence has simple preparation process, adopts ultra-high temperature instantaneous sterilization or pasteurization, effectively retains active ingredients of honey and raw materials, has the effect of improving respiratory tract immunity, can be directly taken or taken with water, and is convenient to eat.
Detailed Description
In order to enable those skilled in the art to better understand the technical solution of the present invention, the following detailed description is provided for specific embodiments thereof:
example 1:
a plant honey essence for improving respiratory tract immunity comprises 1g of composition (superfine powder) for improving respiratory tract immunity and 9g of fructus Sichuan style fruit honey. The composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
The plant honey essence for improving respiratory tract immunity is prepared by the following steps:
s1, preparing a composition (superfine powder) for improving respiratory tract immunity: the composition for improving respiratory tract immunity is prepared by adopting an ultrafine powder process, and comprises the following specific steps of: weighing 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of emblic leafflower fruit, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of small yellow ginger in Yunnan, 30 parts of turmeric and 50 parts of black pepper, placing all the components into a traditional Chinese medicine powdering machine for preliminary crushing, and sieving with a No. 5 sieve (180 mu m +/-7.6 mu m,80 meshes); then placing the screened medicinal materials into an ultrafine grinder, and grinding by the ultrafine grinder to obtain a composition (ultrafine powder) for improving respiratory tract immunity, wherein the parameters of the ultrafine grinder are that the rotating speed is 400rpm, the time is 30min, the ball-to-material ratio is 10:1, and the size and the ball (7 mm:3 mm) =1:4;
s2, honey treatment: taking 9g of Sichuan fruit honey, and heating for standby;
s3, adding 9g of the Sichuan style fruit honey in the step S2 into a beaker (stirring equipment), and uniformly mixing for 20min by using a magnetic stirrer;
s4, taking 1g of the composition (superfine powder) for improving the respiratory tract immunity prepared in the step S1, adding the composition into the uniformly stirred honey for 4 times, and stirring at a medium speed for 20min by using a magnetic stirrer;
s5, a sterilization step: pasteurizing;
s6, discharging to obtain the plant honey essence product for improving respiratory tract immunity.
Example 2:
a plant honey essence for improving respiratory tract immunity comprises 1g of composition (water extract) for improving respiratory tract immunity and 9g of loquat honey. The composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
The plant honey essence for improving respiratory tract immunity is prepared by the following steps:
s1, preparing a composition (water extract) for improving respiratory tract immunity: the composition for improving respiratory tract immunity is prepared by adopting an aqueous extract extraction process, and comprises the following specific steps: weighing crude drug decoction pieces of each component according to a formula of the composition for improving respiratory immunity, namely weighing 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of peppermint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seeds, 10 parts of fructus momordicae, 3 parts of small yellow ginger in Yunnan, 30 parts of turmeric and 50 parts of black pepper; mashing fructus Phyllanthi, fructus Perillae, fructus Siraitiae Grosvenorii and fructus Piperis, sieving with 4 mesh standard sieve, mixing the mashed crude drug decoction pieces with other crude drug decoction pieces; adding 10 times of water, heating and refluxing for 3 hours at 100 ℃, filtering the extracting solution by using a 200-mesh sieve, heating and extracting for 1-3 times, filtering, merging all filtrate, vacuum concentrating to 1/10 of the original filtrate volume, and vacuum concentrating parameters: the temperature is 60 ℃ and the vacuum degree is 100mbar; then freeze-drying the concentrated solution to obtain a composition (aqueous extract) for improving respiratory tract immunity;
s2, honey treatment: heating loquat honey in water bath at 40 ℃ for decrystallization for later use;
s3, adding 9g of loquat honey processed in the step S2 into a beaker (stirring equipment), and uniformly mixing for 20min by using a magnetic stirrer;
s4, taking 1g of the composition (water extract) for improving respiratory tract immunity prepared in the step S1, adding the composition into the uniformly stirred honey for 4 times, and stirring at a medium speed for 20min by using a magnetic stirrer;
s5, a sterilization step: pasteurizing;
s6, discharging to obtain the plant honey essence product for improving respiratory tract immunity.
Example 3:
a plant honey essence for improving respiratory tract immunity comprises 1.83g of composition (water extract and superfine powder) for improving respiratory tract immunity and 8.17g of loquat honey. The composition for improving respiratory tract immunity is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
The plant honey essence for improving respiratory tract immunity is prepared by the following steps:
s1, preparing a composition (aqueous extract and superfine powder) for improving respiratory tract immunity, wherein the step comprises the following steps of: the composition for improving the respiratory tract immunity is prepared by adopting an aqueous extract extraction process and an ultrafine powder process, and comprises the following specific steps of:
A. weighing crude drug decoction pieces of the components according to the formula of the composition for improving respiratory tract immunity, namely weighing 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seeds, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper;
B. placing 30 parts of phyllanthus emblica, 20 parts of Chinese yam, 10 parts of perilla seed, 10 parts of momordica grosvenori and 50 parts of black pepper into a traditional Chinese medicine powder grinding machine for preliminary grinding, sieving with a No. 5 sieve (180 mu m plus or minus 7.6 mu m,80 meshes), and then grinding by adopting an ultrafine grinder to obtain ultrafine powder for standby, wherein the parameters of the ultrafine grinder are that the rotating speed is 400rpm, the time is 30min, the ball-to-ball ratio is 10:1, and the size and the ball (7 mm:3 mm) =1:4;
C. mixing 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of liquorice, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 3 parts of yellow ginger with Yunnan and 30 parts of turmeric, adding 10 times of water, heating and refluxing for 3 hours at 100 ℃, filtering an extracting solution by using a 200-mesh sieve, repeatedly heating and extracting for 3 times, filtering, combining all filtrate, concentrating in vacuum to 1/10 of the volume of the original filtrate, concentrating in vacuum with the vacuum concentration parameter of 60 ℃ and the vacuum degree of 100mbar, then freeze-drying the concentrated solution to prepare water extract freeze-dried powder, and sieving coarse powder by using a grain sizing machine;
D. mixing 1.2 parts of superfine powder obtained in the step B and 0.63 part of water extract freeze-dried powder obtained in the step C, and then placing the mixture into a superfine pulverizer to pulverize the mixture to obtain a composition (water extract+superfine powder) for improving respiratory tract immunity, wherein the parameters of the superfine pulverizer are that the rotating speed is 300rpm, the time is 5min, the ball-to-material ratio is 5:1, and the size and the ball (7 mm:3 mm) =1:4 are mixed to obtain 1.83 parts which are the minimum part unit of the composition for improving respiratory tract immunity; the minimum mixing mass ratio of the superfine powder to the water extract freeze-dried powder is 1.2:0.63;
s2, honey treatment: heating loquat honey in water bath at 40 ℃ for decrystallization for later use;
s3, adding 8.17g of loquat honey treated in the step S2 into a beaker (stirring equipment), and uniformly mixing for 20min by using a magnetic stirrer;
s4, taking 1.83g of the composition (water extract and superfine powder) for improving respiratory tract immunity prepared in the step S1, adding the composition into the uniformly stirred honey for 4 times, and stirring at medium speed for 20min by using a magnetic stirrer;
s5, a sterilization step: pasteurizing;
s6, discharging to obtain the plant honey essence product for improving respiratory tract immunity.
Efficacy validation experiment of the composition for improving respiratory tract immunity:
through the test of 10 persons in 4 days, the medicine has the tendency of improving 10 symptoms of cough, hypodynamia, mental retardation, slow brain reaction, asthma or shortness of breath, somnolence, taste/smell decline, expectoration, nasal obstruction/running nose and low emotion, and particularly has obvious improvement in the aspects of symptoms of cough, expectoration, hypodynamia, somnolence, mental retardation and the like.
The specific test process of human body test clothes is as follows:
the testers of the intervention group select 10 people infected with new post-coronary respiratory tract discomfort to test the respiratory tract immunity improving composition of the invention, continuously test for 4 days, score each person according to symptom improvement condition every day, and then carry out statistical analysis according to the score to evaluate the effectiveness of the product formula.
Meanwhile, a control group is set, 10 persons infected with new post-coronary respiratory tract discomfort are selected from the control group, the composition for improving respiratory tract immunity is not taken, scoring is carried out according to the symptoms of each person every day, and then statistical analysis is carried out according to the scoring.
1. Product morphology: the composition for improving respiratory tract immunity in the form of a teabag (3.8 g/bag) is prepared from the following components in parts by weight: 100 parts of honeysuckle, 50 parts of dried orange peel, 30 parts of phyllanthus emblica, 30 parts of liquorice, 20 parts of Chinese yam, 20 parts of mint, 20 parts of ampelopsis grossedentata leaves, 10 parts of perilla seed, 10 parts of fructus momordicae, 3 parts of yellow ginger in Yunnan province, 30 parts of turmeric and 50 parts of black pepper.
2. The administration method comprises the following steps: each person takes the medicine 2 times a day, 1 bag each time, and the medicine is taken after being brewed with boiled water for 5 minutes.
3. The panelist of the intervention group: 10 patients with new post-coronal respiratory distress;
4. personnel of the control group: 10 patients with new post-coronal respiratory distress;
5. scoring indexes: 16 indices-cough, asthma or shortness of breath, expectoration, debilitation, somnolence, stuffy nose/runny nose, mental retardation, insomnia, gastrointestinal discomfort, taste and smell deterioration, chest pain caused by cough, low emotion, occasional dizziness, arthralgia, occasional palpitation, and slow brain bag reaction-each index was set for 1-5 minutes, and a smaller score indicates a more alleviation of symptoms.
6. The statistics of the improvement of symptoms caused by respiratory tract immunity disorder in the intervention group are shown in table 1:
table 1:
in table 1, the values are expressed as mean±standard deviation (mean±sem); * Represent vs.0Days (compare to day 0 data), P <0.05; * Represent vs.0days (compare to day 0 data), P <0.01; * vs.0Days (compare to day 0 data), P <0.001.
7. The statistics of the symptoms caused by the airway immunity disorder of the control group are shown in Table 2:
table 2:
in table 2, the values are expressed as mean±standard deviation (mean±sem); # represents vs.1Days (compared to day 1), P <0.05.
Compared with the data in the tables 1 and 2, the composition for improving respiratory tract immunity of the present invention has a tendency to improve 10 symptoms such as cough, hypodynamia, mental retardation, slowed down of mental reaction, asthma or shortness of breath, sleepiness, taste/smell deterioration, expectoration, nasal obstruction/running nose and depressed mood, and has a remarkable improving effect especially on the symptoms such as cough, expectoration, hypodynamia, sleepiness, mental retardation, etc.
The plant honey essence composition for improving the respiratory tract immunity selects medicinal and edible flavors or extracts thereof with the effect of improving the respiratory tract immunity, and honeysuckle, dried orange peel, liquorice and phyllanthus emblica in the composition have the effects of clearing heat and detoxicating, eliminating dampness and resolving phlegm, tonifying spleen and nourishing stomach, promoting the production of body fluid to quench thirst, and is matched with ampelopsis grossedentata leaves, perilla seeds, mint, small yellow ginger in Yunnan, chinese yam, momordica grosvenori with the effects of promoting diuresis, resolving phlegm and relieving cough, eliminating phlegm and relieving sore throat, tonifying lung qi and the like. In addition, turmeric and black pepper which have auxiliary improving effect on symptoms caused by respiratory tract immunity disorder are added into the composition, so that the effect of improving respiratory tract immunity is comprehensively achieved. The honey is not cold and not dry, has the function of tonifying middle-jiao and moistening dryness, can bring different sweet tastes by using different types of honey, has no additive in the product, has high product purity, and is a product suitable for the old and the young.
In summary, the plant honey essence for improving the respiratory tract immunity and the preparation process thereof select the medicinal and edible homology and have the medicinal taste for improving the respiratory tract immunity or the extract thereof for combination and compounding, so that the symptoms of cough, expectoration, hypodynamia, somnolence, mental inadequacy and the like caused by the respiratory tract immunity and the disorder of the human body can be comprehensively improved through the multi-channel conditioning of the human body, and all the components meet the requirements of food regulations and have safety; the plant honey essence has high purity, no water is added in the process, and the finished product has the characteristic of fragrant and sweet taste according to the types of different nectar used in the preparation process; the honey essence has simple preparation process, adopts ultra-high temperature instantaneous sterilization or pasteurization, effectively retains active ingredients of honey and raw materials, has the effect of relieving various uncomfortable symptoms after new crown rehabilitation, can be directly taken or taken with water, and is convenient to eat.
It will be appreciated by persons skilled in the art that the above embodiments are provided for illustration only and not for limitation of the invention, and that variations and modifications of the above described embodiments are intended to fall within the scope of the claims of the invention as long as they fall within the true spirit of the invention.

Claims (9)

1. The plant honey essence for improving the respiratory tract immunity is characterized by comprising 10-30% of a composition for improving the respiratory tract immunity and 70-90% of honey by mass, wherein the composition for improving the respiratory tract immunity is prepared from the following components in parts by weight: 50-150 parts of honeysuckle, 20-80 parts of dried orange peel, 10-50 parts of phyllanthus emblica, 10-50 parts of liquorice, 10-30 parts of Chinese yam, 10-30 parts of peppermint, 10-30 parts of ampelopsis grossedentata leaf, 5-15 parts of perilla seed, 5-15 parts of fructus momordicae, 1-5 parts of Yunnan yellow ginger, 12-48 parts of turmeric and 20-80 parts of black pepper.
2. A plant honey essence for improving the immunity of the respiratory tract as claimed in claim 1, wherein the honey is solid honey and/or liquid honey.
3. The plant honey essence for improving respiratory tract immunity of claim 1, wherein the honey is at least one of Tibetan honey, snowy honey, shanglira winter honey, loquat honey, elsholtzia rugulosa seed honey, crystallized soil honey and cesarean.
4. The plant honey essence for improving respiratory tract immunity according to claim 1, wherein each component in the composition for improving respiratory tract immunity adopts crude drug decoction piece water extract or crude drug decoction piece superfine powder, or part of components in the composition for improving respiratory tract immunity adopts crude drug decoction piece superfine powder, and the rest components adopt crude drug decoction piece water extract.
5. A process for preparing plant honey essence for improving respiratory tract immunity as claimed in claim 1, which is characterized by comprising the following steps:
s1, preparing a composition for improving respiratory tract immunity, which comprises the following steps: the composition for improving the respiratory tract immunity is prepared by adopting an aqueous extract extraction process and/or an ultrafine powder process;
s2, honey treatment: the honey is used for decrystallization when being solid honey, and the honey is used for decrystallization when being liquid honey;
s3, adding the honey processed in the step S2 with the mass fraction of 70-90% into stirring equipment, and stirring and uniformly mixing for 10-20 min;
s4, taking the composition for improving the respiratory tract immunity prepared in the step S1 with the mass fraction of 10-30%, adding the composition into the stirring equipment in the step S3 for multiple times, and uniformly stirring and mixing the composition with the honey in the stirring equipment for 10-20 min;
s5, a sterilization step: adopts ultra-high temperature instantaneous sterilization or pasteurization;
s6, discharging to obtain the plant honey essence product for improving respiratory tract immunity.
6. The process for preparing plant honey essence for improving respiratory tract immunity according to claim 5, wherein in the step S1, the composition for improving respiratory tract immunity is prepared by adopting an aqueous extract extraction process, and the specific steps are as follows: the method for improving respiratory tract immunity comprises the steps of weighing crude drug decoction pieces of each component according to the formula of the composition for improving respiratory tract immunity according to claim 1, sieving the crude drug decoction pieces with a standard sieve of 3-5 meshes after mashing or mashing, adding 10-15 times of water by volume after uniform mixing, heating and refluxing for 1.5-3 hours at 90-100 ℃, filtering the obtained extract by using a sieve of 150-300 meshes, repeatedly heating and extracting for 1-3 times, filtering, merging all filtrate, concentrating the filtrate under vacuum at the temperature of 50-70 ℃ and the vacuum degree of 70-100 mbar to 1/5-1/10 of the original filtrate volume, and then freeze-drying the concentrated solution to obtain the composition for improving respiratory tract immunity.
7. The process for preparing plant honey essence for improving respiratory tract immunity according to claim 5, wherein in the step S1, the specific steps of preparing the composition for improving respiratory tract immunity by adopting an ultra-fine powder process are as follows: the method for preparing the composition for improving respiratory tract immunity according to claim 1 comprises weighing crude drug decoction pieces of each component, placing into a traditional Chinese medicine powder grinding machine for preliminary grinding, sieving with No. 4 sieve or No. 5 sieve, and pulverizing with an ultra-micro pulverizer to obtain the composition for improving respiratory tract immunity.
8. The process for preparing plant honey essence for improving respiratory tract immunity according to claim 5, wherein in the step S1, the composition for improving respiratory tract immunity is prepared by adopting an aqueous extract extraction process and an ultrafine powder process, and the preparation method comprises the following specific steps:
A. weighing crude drug decoction pieces of each component according to the formula of the composition for improving respiratory tract immunity as claimed in claim 1;
B. placing crude drug decoction pieces of a part of the components in a traditional Chinese medicine powder grinding machine for preliminary grinding, passing through a No. 4 sieve or a No. 5 sieve, and then grinding by an ultrafine grinder to obtain ultrafine powder for later use;
C. the crude drug decoction pieces of the rest components are not required to be smashed or smashed and then pass through a standard sieve with 3 meshes to 5 meshes, water with 10 to 15 times of volume is added after the mixture is evenly mixed, heating reflux is carried out for 1.5 to 3 hours at the temperature of 90 to 100 ℃, the obtained extract is filtered by a sieve with 150 meshes to 300 meshes, heating extraction is repeated for 1 to 3 times and filtering, all the filtrates are combined, vacuum concentration is carried out to 1/5 to 1/10 of the volume of the original filtrate under the conditions of the temperature of 50 to 70 ℃ and the vacuum degree of 70 to 100mbar, and then the concentrated liquid is freeze-dried to obtain freeze-dried powder of the water extract for standby;
D. and then mixing the superfine powder obtained in the step B and the water extract freeze-dried powder obtained in the step C, and then placing the mixture in a superfine pulverizer to pulverize so as to obtain the composition for improving the respiratory tract immunity.
9. The process for preparing plant honey essence for improving respiratory tract immunity according to claim 7 or 8, wherein the rotating speed of the superfine pulverizer is 300-400 rpm, the pulverizing time is 20-40 min, the ball-to-material ratio (5-20): 1, and the ratio of the big balls to the small balls is 1 (1-6).
CN202310295061.4A 2023-03-24 2023-03-24 Plant honey essence for improving respiratory tract immunity and preparation process thereof Pending CN116474056A (en)

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