CN116195594A - Disinfection cleaning agent and preparation method and application thereof - Google Patents
Disinfection cleaning agent and preparation method and application thereof Download PDFInfo
- Publication number
- CN116195594A CN116195594A CN202211736293.0A CN202211736293A CN116195594A CN 116195594 A CN116195594 A CN 116195594A CN 202211736293 A CN202211736293 A CN 202211736293A CN 116195594 A CN116195594 A CN 116195594A
- Authority
- CN
- China
- Prior art keywords
- cleaning agent
- hydrogen peroxide
- disinfection
- parts
- succinic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004659 sterilization and disinfection Methods 0.000 title claims abstract description 54
- 239000012459 cleaning agent Substances 0.000 title claims abstract description 39
- 238000002360 preparation method Methods 0.000 title abstract description 5
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 54
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 claims abstract description 23
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims abstract description 20
- 230000001954 sterilising effect Effects 0.000 claims abstract description 14
- 239000004094 surface-active agent Substances 0.000 claims abstract description 14
- -1 alkyl glycoside Chemical class 0.000 claims abstract description 12
- 229930182470 glycoside Natural products 0.000 claims abstract description 12
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims abstract description 10
- 229940098779 methanesulfonic acid Drugs 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 9
- 239000002904 solvent Substances 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 8
- 238000011012 sanitization Methods 0.000 claims description 8
- 230000000249 desinfective effect Effects 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000001816 cooling Methods 0.000 claims description 4
- ORUDEUCNYHCHPB-OUUBHVDSSA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-tetradecoxyoxane-3,4,5-triol Chemical compound CCCCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ORUDEUCNYHCHPB-OUUBHVDSSA-N 0.000 claims description 3
- 150000004702 methyl esters Chemical class 0.000 claims description 3
- 239000003960 organic solvent Substances 0.000 claims description 3
- 235000012424 soybean oil Nutrition 0.000 claims description 3
- 239000003549 soybean oil Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 14
- 238000004140 cleaning Methods 0.000 abstract description 12
- 239000001384 succinic acid Substances 0.000 abstract description 5
- 238000006065 biodegradation reaction Methods 0.000 abstract description 4
- 239000003795 chemical substances by application Substances 0.000 abstract description 4
- 239000003381 stabilizer Substances 0.000 abstract description 4
- 231100000956 nontoxicity Toxicity 0.000 abstract description 3
- 230000000638 stimulation Effects 0.000 abstract description 3
- 230000000295 complement effect Effects 0.000 abstract description 2
- 230000002708 enhancing effect Effects 0.000 abstract description 2
- 239000003206 sterilizing agent Substances 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract description 2
- 230000000052 comparative effect Effects 0.000 description 14
- 238000012360 testing method Methods 0.000 description 9
- 239000000645 desinfectant Substances 0.000 description 8
- 241000191967 Staphylococcus aureus Species 0.000 description 7
- 239000000463 material Substances 0.000 description 7
- 238000003756 stirring Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 6
- 241000700605 Viruses Species 0.000 description 5
- 241001678559 COVID-19 virus Species 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 241000711573 Coronaviridae Species 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000588915 Klebsiella aerogenes Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 239000003599 detergent Substances 0.000 description 2
- 229940092559 enterobacter aerogenes Drugs 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 231100000053 low toxicity Toxicity 0.000 description 2
- 150000002978 peroxides Chemical class 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000005507 spraying Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 208000025721 COVID-19 Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000714201 Feline calicivirus Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000701074 Human alphaherpesvirus 2 Species 0.000 description 1
- 241000713772 Human immunodeficiency virus 1 Species 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 241000588747 Klebsiella pneumoniae Species 0.000 description 1
- RJQXTJLFIWVMTO-TYNCELHUSA-N Methicillin Chemical compound COC1=CC=CC(OC)=C1C(=O)N[C@@H]1C(=O)N2[C@@H](C(O)=O)C(C)(C)S[C@@H]21 RJQXTJLFIWVMTO-TYNCELHUSA-N 0.000 description 1
- 241001263478 Norovirus Species 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241001138501 Salmonella enterica Species 0.000 description 1
- 206010041925 Staphylococcal infections Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 239000003623 enhancer Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000004880 explosion Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 208000037797 influenza A Diseases 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 208000015688 methicillin-resistant staphylococcus aureus infectious disease Diseases 0.000 description 1
- 229960003085 meticillin Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 238000011056 performance test Methods 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P3/00—Fungicides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/08—Cleaning involving contact with liquid the liquid having chemical or dissolving effect
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/02—Inorganic compounds ; Elemental compounds
- C11D3/04—Water-soluble compounds
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/2075—Carboxylic acids-salts thereof
- C11D3/2082—Polycarboxylic acids-salts thereof
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/34—Organic compounds containing sulfur
- C11D3/3409—Alkyl -, alkenyl -, cycloalkyl - or terpene sulfates or sulfonates
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/24—Medical instruments, e.g. endoscopes, catheters, sharps
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a disinfection cleaning agent and a preparation method and application thereof. The disinfection cleaning agent comprises the following components: alkyl glycoside surfactant, succinic acid, hydrogen peroxide and methylsulfonic acid. In the disinfection cleaning agent, on the premise that succinic acid is used as a stabilizer, methanesulfonic acid is used as a hydrogen peroxide synergist, so that the stability and the high efficiency of the disinfection and sterilization effect are ensured; the alkyl glycoside surfactant is used as a cleaning main agent, has low surface tension, good detergency, good solubility, good compatibility with skin, no toxicity, no stimulation and rapid and complete biodegradation. Besides the respective effects, the sterilizing agent and the cleaning surfactant have the effect of obviously enhancing the cleaning effect, and the components complement each other and have the synergistic effect.
Description
Technical Field
The invention relates to the technical field related to disinfection, sterilization and cleaning, in particular to a disinfection cleaning agent and a preparation method and application thereof.
Background
Traditional disinfectants such as alcohol, chlorine-containing disinfectants, peroxides can inactivate viruses. However, the traditional chemical disinfectant has certain toxicity and strong irritation, is easy to damage skin tissues, respiratory systems and the like after long-term use, and can damage the environment in the production and use processes. There is also a safety risk in the use of chemical disinfectants in large quantities, and there is a risk of explosion initiation in public areas where large quantities of disinfectants such as alcohol are sprayed. Disinfectants containing chlorine or peroxides also present residual problems, with potential risks to both humans and the environment.
The ideal disinfectant has the advantages of wide sterilization spectrum, strong sterilization capability, high action speed, good stability, low toxicity, corrosiveness and small irritation. Therefore, it is necessary to develop a more environmentally effective viral disinfectant.
Disclosure of Invention
The first technical problem to be solved by the invention is as follows:
a disinfecting detergent is provided.
The second technical problem to be solved by the invention is as follows:
a preparation method of the disinfection cleaning agent is provided.
The third technical problem to be solved by the invention is:
the application of the disinfection cleaning agent.
In order to solve the first technical problem, the invention adopts the following technical scheme:
the disinfection cleaning agent comprises the following components:
alkyl glycoside surfactant, succinic acid, hydrogen peroxide and methylsulfonic acid.
According to the embodiments of the present invention, one of the technical solutions has at least one of the following advantages or beneficial effects:
the alkyl glycoside surfactant is a nonionic surfactant made from renewable plant raw materials. Has no stimulation to human body, extremely low toxicity and quick biodegradation; the surface tension is low, the detergency is good, the solubility is good, and the mildness of the formula can be obviously improved; has good compatibility with skin, no toxicity, no irritation and rapid and complete biodegradation.
The succinic acid is a good performing chelating agent. In the process of chelating metal impurity ions, the hydrogen peroxide is helped to be stable and not to be catalytically decomposed, and the storage time of cargoes is prolonged.
The hydrogen peroxide is used as a main agent for disinfection and sterilization, and is used as a natural compound in the earth atmosphere, hydrogen peroxide (H) 2 O 2 ) The environment-friendly water purifier has more sustainable performance, is safer on the surface, does not leave any residues when nontoxic components are decomposed into water and oxygen, and meets the severe requirements of various environmental protection certification.
The methylsulfonic acid is a stabilizer. The introduction of the methylsulfonic acid can enhance the disinfection and sterilization activity of the hydrogen peroxide and shorten the disinfection time of the hydrogen peroxide.
In the disinfection cleaning agent, on the premise that succinic acid is used as a stabilizer, methanesulfonic acid is used as a hydrogen peroxide synergist, so that the stability and the high efficiency of the disinfection and sterilization effect are ensured; the alkyl glycoside surfactant is used as a cleaning main agent, has low surface tension, good detergency, good solubility, good compatibility with skin, no toxicity, no stimulation and rapid and complete biodegradation. Besides the respective effects, the sterilizing agent and the cleaning surfactant have the effect of obviously enhancing the cleaning effect, and the components complement each other and have the synergistic effect.
According to one embodiment of the invention, the alkyl glycoside surfactant comprises APG0810.APG0810 is one of the alkyl glycoside surfactants.
According to one embodiment of the invention, the composition comprises the following components in parts by weight:
0.1-0.3 part of alkyl glycoside surfactant, 0.2-0.5 part of succinic acid, 1-3 parts of hydrogen peroxide and 0.1-0.5 part of methanesulfonic acid.
Under the weight parts, the disinfection cleaning agent disclosed by the invention can achieve the optimal sterilization effect and the optimal stability.
According to one embodiment of the invention, the mass concentration of the hydrogen peroxide is 25% -27.5%.
The concentration of the hydrogen peroxide is too low, so that viruses cannot be killed within 1 minute, and when the concentration of the hydrogen peroxide is too high, the stability of a disinfection cleaning agent system can be damaged, and based on the fact that the mass concentration of the hydrogen peroxide in the disinfection cleaning agent is 25% -27.5%, the high efficiency of disinfection and sterilization effects and the stability of disinfection and sterilization are guaranteed.
According to one embodiment of the invention, the composition further comprises the following components in parts by weight:
14-16 parts of at least one of myristyl glucoside and 4-5 parts of soybean oil methyl ester.
The soybean oil methyl ester is a safe and environment-friendly organic solvent, and can promote the solubility of the disinfection cleaning agent. The myristyl glucoside is a detergent, can promote the detergency of the disinfection cleaning agent disclosed by the invention, and further can adapt to a high-alkali environment, so that the application of the disinfection cleaning agent disclosed by the invention is facilitated to be expanded.
According to one embodiment of the invention, the composition further comprises the following components:
at least one of essence, water solvent and organic solvent.
In order to solve the second technical problem, the invention adopts the following technical scheme:
a method of preparing the sanitizing cleanser comprising the steps of:
and under the condition of heating or cooling, mixing the alkyl glycoside surfactant, the succinic acid, the hydrogen peroxide and the methanesulfonic acid in a solvent to obtain the disinfection cleaning agent.
According to one embodiment of the invention, the components are mixed in the solvent for a period of 15-30 minutes.
According to one embodiment of the invention, the steps of stirring are also included after mixing the components, the stirring speed being 15-50r/min.
According to one embodiment of the invention, the solvent is split into two parts, the first part comprising 80% of the total volume and the second part comprising 20% of the total volume.
According to one embodiment of the invention, the components are dissolved in a first part of solvent before adding a second part of solvent.
According to one embodiment of the invention, the temperature is 25-45 ℃ under the heating condition.
According to one embodiment of the invention, the temperature is 10-25 ℃ under the cooling condition.
The disinfection cleaning agent can be used on hard, nonporous and non-food contact surfaces of bathroom devices, counters, tables, door handles, chairs, tables, telephones and the like; in addition, it can be used for the disinfection of hospitals, nursing homes, infectious rescue vehicles, schools, restaurants, hotels, motels, commercial office buildings, fitness facilities, bathrooms, shower and bath areas, trains and airports.
The disinfection cleaning agent integrates cleaning and disinfection functions, can synchronously finish cleaning and disinfection, can sterilize hard, nonporous and non-food contact surfaces within one minute, and can kill enterobacter aerogenes and staphylococcus aureus.
The disinfection cleaning agent has good sterilization performance on the following bacteria and viruses, and can kill the following bacteria and viruses within 1 minute:
pseudomonas aeruginosa
Staphylococcus aureus
Salmonella enterica
Enterobacter aerogenes
Coli bacterium
Klebsiella pneumoniae
Methicillin-resistant staphylococcus aureus (MRSA)
SARS-associated coronavirus, e.g. SARS-CoV-2 and COVID-19
Herpes simplex type 2 herpes (ATCC VR-734, G strain)
HIV-1 (HTLC-lllB strain)
Influenza A/H3N2 (ATCC VR-544, strain A/H3N 2/8/68)
Norovirus (ATCC-VR-782)
Feline calicivirus (ATCC VR-782).
In another aspect, the invention also relates to the application of the disinfection cleaner in medical instrument sterilization. Comprising a sanitizing agent as described in the embodiment of aspect 1 above. The application adopts all the technical schemes of the disinfection cleaning agent of the embodiment, so that the disinfection cleaning agent has at least all the beneficial effects brought by the technical schemes of the embodiment.
Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Detailed Description
In the description of the present invention, the description of first, second, etc. is for the purpose of distinguishing between technical features only and should not be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
The technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to fall within the scope of the invention.
Example 1
Preparing a disinfection cleaning agent, which comprises the following steps:
adding about 80% of water into a mixing tank according to parts by weight, heating to 45 ℃, sequentially adding 0.5 part of succinic acid, 0.5 part of methylsulfonic acid, 0.3 part of APG 0810.3 part of 27.5% hydrogen peroxide and 0.5 part of essence under stirring, sequentially adding in sequence, and adding the next material after each material is completely dissolved; adding 20% water, stirring for 15min to obtain transparent solution.
Example 2
Preparing a disinfection cleaning agent, which comprises the following steps:
adding about 80% of water into a mixing tank according to parts by weight, heating to 35 ℃, sequentially adding 0.3 part of succinic acid, 0.3 part of methylsulfonic acid, 0.2 part of APG0810, 2 parts of 27.5% hydrogen peroxide and 0.3 part of essence under stirring, sequentially adding in sequence, and adding the next material after each material is completely dissolved; 20% water was added and stirred for 25min to give a clear solution.
Example 3
Preparing a disinfection cleaning agent, which comprises the following steps:
adding about 80% of water into a mixing tank according to parts by weight, adding 0.2 part of succinic acid, 0.1 part of methanesulfonic acid, 0.1 part of APG0810, 1 part of 27.5% hydrogen peroxide and 0.1 part of essence into the mixing tank at normal temperature in sequence under stirring, and adding the next material after each material is completely dissolved; adding 20% water, stirring for 30min to obtain transparent solution.
Comparative example 1
A cleaning agent was prepared in this comparative example, which differs from example 2 in that APG0810 was absent, except that the other conditions were the same.
Comparative example 2
A cleaning agent was prepared in this comparative example, which differs from example 2 in that 27.5% hydrogen peroxide was absent, and the other conditions were the same.
Comparative example 3
A cleaning agent was prepared in this comparative example, which differs from example 2 in that succinic acid was absent, and the other conditions were the same.
Comparative example 4
A cleaning agent was prepared in this comparative example, which differs from example 2 in that methylsulfonic acid was absent, with the other conditions being the same.
Performance test:
test examples
The test example tests 7 tables and stools of isolation rooms of novel coronavirus infectors respectively for the disinfection cleaning agent prepared in the examples 1-3 and the cleaning agent prepared in the comparative examples 1-4. The disinfection cleaner prepared in the invention examples 1-3 was stored in a warehouse for more than one year for testing. Specifically:
test microorganism: staphylococcus aureus, escherichia coli, covd-19 virus.
1. The test basis is as follows:
staphylococcus aureus and escherichia coli are subjected to the sanitary standard of disposable sanitary products according to GB 15979-2002;
the COVID-19 virus is in accordance with WS/T775-2021 standard;
the instrument comprises normal-temperature trigger spraying, and detects the antibacterial effect of the stock solution on staphylococcus aureus and escherichia coli for 1 minute according to the practical use condition.
2. Test materials and methods:
detection conditions: culturing Staphylococcus aureus, escherichia coli and COVID-19 virus, collecting culture solution, and spraying the above microorganism onto the table and chair.
Wherein the bacterial culture temperature is 36+/-1 ℃; the culture period is 72 hours;
the fungus culture temperature is 28+/-1 ℃; the incubation period was 72 hours.
The COVID-19 virus was cultured in the BSL-3 laboratory under the condition of WS/T775-2021, which was commissioned to perform the novel experiment for coronavirus culture.
In each of the above tables and chairs sprayed with the above microorganisms, 7 squares of equal area were taken, and the disinfecting cleaners of examples 1 to 3 and comparative examples 1 to 4 were sprayed into the squares, respectively, and the cleanliness and antibacterial rate of the squares were tested after 1 minute.
3. Test results:
the test results are shown in Table 1.
TABLE 1
As can be seen from Table 1, the disinfecting cleaning agents of examples 1 to 3 are excellent in both cleaning and disinfecting effects; in contrast, comparative example 1 lacks APG0810, which results in a reduced cleaning effect of the cleaning agent, and the disinfecting effect is not affected; the comparative example 2 defaults to hydrogen peroxide, has less influence on the cleaning effect, but the disinfection effect is obviously poor; comparative example 3 defaults succinic acid as a hydrogen peroxide stabilizer, the hydrogen peroxide is decomposed and deactivated, and the sterilizing effect is remarkably deteriorated; comparative example 4 defaults to methylsulfonic acid as a hydrogen peroxide enhancer and the biocidal effect is slightly reduced relative to examples 1-3.
The foregoing is merely exemplary embodiments of the present invention and are not intended to limit the scope of the present invention, and all equivalent modifications made by the present invention or direct or indirect application in the relevant art are intended to be included in the scope of the present invention.
Claims (10)
1. A disinfecting cleaning agent, which is characterized in that: the composition comprises the following components:
alkyl glycoside surfactant, succinic acid, hydrogen peroxide and methylsulfonic acid.
2. A sanitizing cleaning agent as set forth in claim 1, wherein: comprises the following components in parts by weight:
0.1-0.3 part of alkyl glycoside surfactant, 0.2-0.5 part of succinic acid, 1-3 parts of hydrogen peroxide and 0.1-0.5 part of methanesulfonic acid.
3. A sanitizing cleaning agent as set forth in claim 1, wherein: the mass concentration of the hydrogen peroxide is 25% -27.5%.
4. A sanitizing cleaning agent as set forth in claim 1, wherein: the composition also comprises the following components in parts by weight:
14-16 parts of at least one of myristyl glucoside and 4-5 parts of soybean oil methyl ester.
5. A sanitizing cleaning agent as set forth in claim 1, wherein: the composition also comprises the following components:
at least one of essence, water solvent and organic solvent.
6. A method of preparing a sanitizing cleaner according to any one of claims 1 to 5, characterized in that: the method comprises the following steps:
and under the condition of heating or cooling, mixing the alkyl glycoside surfactant, the succinic acid, the hydrogen peroxide and the methanesulfonic acid in a solvent to obtain the disinfection cleaning agent.
7. The method according to claim 6, wherein: the time for mixing the components in the solvent is 15-30min.
8. The method according to claim 6, wherein: the temperature is 25-45 ℃ under the heating condition.
9. The method according to claim 6, wherein: the temperature is 10-25 ℃ under the cooling condition.
10. Use of a sanitizing cleanser as claimed in any one of claims 1 to 5 for the sterilization of medical devices.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211736293.0A CN116195594A (en) | 2022-12-30 | 2022-12-30 | Disinfection cleaning agent and preparation method and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211736293.0A CN116195594A (en) | 2022-12-30 | 2022-12-30 | Disinfection cleaning agent and preparation method and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116195594A true CN116195594A (en) | 2023-06-02 |
Family
ID=86506938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211736293.0A Pending CN116195594A (en) | 2022-12-30 | 2022-12-30 | Disinfection cleaning agent and preparation method and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN116195594A (en) |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101372649A (en) * | 2008-09-24 | 2009-02-25 | 北京洛娃日化有限公司 | Acidic bathroom detergent |
| CN104877813A (en) * | 2015-05-07 | 2015-09-02 | 北京安洁康生物科技有限公司 | Acidic cleaning agent for pasture milking equipment |
| CN107683853A (en) * | 2017-08-01 | 2018-02-13 | 江苏新瑞贝科技股份有限公司 | One kind oxidation cleaning and sterilizing agent and preparation method thereof |
| CN111165478A (en) * | 2020-02-11 | 2020-05-19 | 南通大学 | Foam type sterilization, disinfection and air purification agent and preparation method and application thereof |
| CN111228304A (en) * | 2020-03-11 | 2020-06-05 | 山东名德医疗科技有限公司 | Virus-killing hand-washing-free disinfectant and preparation method thereof |
| CN111700822A (en) * | 2020-07-23 | 2020-09-25 | 广州泰晟生物科技股份有限公司 | Skin disinfectant and preparation method thereof |
| CN111979061A (en) * | 2019-05-23 | 2020-11-24 | 合肥科源应用化工研究所 | Foam detergent for nuclear facilities and preparation method thereof |
| CN114621823A (en) * | 2022-03-30 | 2022-06-14 | 南京军科超材科技有限公司 | Multifunctional cleaning disinfectant and preparation method thereof |
| CN114747568A (en) * | 2022-04-27 | 2022-07-15 | 山东利尔康医疗科技股份有限公司 | Medium-level disinfection wet tissue and preparation method thereof |
| CN115197787A (en) * | 2022-07-22 | 2022-10-18 | 广东红日星实业有限公司 | Cleaning agent and preparation method and application thereof |
-
2022
- 2022-12-30 CN CN202211736293.0A patent/CN116195594A/en active Pending
Patent Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101372649A (en) * | 2008-09-24 | 2009-02-25 | 北京洛娃日化有限公司 | Acidic bathroom detergent |
| CN104877813A (en) * | 2015-05-07 | 2015-09-02 | 北京安洁康生物科技有限公司 | Acidic cleaning agent for pasture milking equipment |
| CN107683853A (en) * | 2017-08-01 | 2018-02-13 | 江苏新瑞贝科技股份有限公司 | One kind oxidation cleaning and sterilizing agent and preparation method thereof |
| CN111979061A (en) * | 2019-05-23 | 2020-11-24 | 合肥科源应用化工研究所 | Foam detergent for nuclear facilities and preparation method thereof |
| CN111165478A (en) * | 2020-02-11 | 2020-05-19 | 南通大学 | Foam type sterilization, disinfection and air purification agent and preparation method and application thereof |
| CN111228304A (en) * | 2020-03-11 | 2020-06-05 | 山东名德医疗科技有限公司 | Virus-killing hand-washing-free disinfectant and preparation method thereof |
| CN111700822A (en) * | 2020-07-23 | 2020-09-25 | 广州泰晟生物科技股份有限公司 | Skin disinfectant and preparation method thereof |
| CN114621823A (en) * | 2022-03-30 | 2022-06-14 | 南京军科超材科技有限公司 | Multifunctional cleaning disinfectant and preparation method thereof |
| CN114747568A (en) * | 2022-04-27 | 2022-07-15 | 山东利尔康医疗科技股份有限公司 | Medium-level disinfection wet tissue and preparation method thereof |
| CN115197787A (en) * | 2022-07-22 | 2022-10-18 | 广东红日星实业有限公司 | Cleaning agent and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0938542B1 (en) | Aqueous disinfecting cleaning composition | |
| JPS62500240A (en) | Germicidal cleaning formulations | |
| US9795132B2 (en) | Couplers for medium-chain fatty acids and disinfecting compositions | |
| CA2272062A1 (en) | Mycobactericidal compositions | |
| JP4846292B2 (en) | Cleaning and disinfecting composition and method of use thereof | |
| AU2011247875B1 (en) | Disinfectant Compositions and Uses Thereof | |
| CN111165478A (en) | Foam type sterilization, disinfection and air purification agent and preparation method and application thereof | |
| CN112022732A (en) | Hand-washing-free disinfectant and preparation method thereof | |
| CN113491709A (en) | Multifunctional efficient compound disinfectant and preparation method thereof | |
| CN114621823A (en) | Multifunctional cleaning disinfectant and preparation method thereof | |
| US11871749B2 (en) | Alcohol-free hydrogen peroxide disinfectant compositions and methods of use thereof | |
| AU680536B2 (en) | Disinfectant-detergent composition | |
| CN114747568A (en) | Medium-level disinfection wet tissue and preparation method thereof | |
| EP0175338A2 (en) | Disinfectants and antiseptics | |
| CN1978612A (en) | Disinfecting detergent powder, and its preparing method | |
| CN113481067A (en) | Laundry detergent with anti-bacterial function and preparation method thereof | |
| CN102475644A (en) | medical hand sanitizer | |
| CN116195594A (en) | Disinfection cleaning agent and preparation method and application thereof | |
| EP0255875B1 (en) | Glutaraldehyde-based sterilising composition of antibacterial and antimycotic activity in an aqueous vehicle | |
| CN106727108A (en) | A kind of hand cleanser and preparation method thereof | |
| CN112680295A (en) | Efficient sterilization concentrated detergent containing povidone iodine and preparation method thereof | |
| CN111226977A (en) | Environment-friendly sterilizing agent for medical instruments and preparation method thereof | |
| US5250573A (en) | Glutaraldehyde-based sterilising composition of antibacterial and antimycotic activity, in an aqueous vehicle | |
| JP3322286B2 (en) | Washing soap | |
| RU2624845C1 (en) | Disinfectant with washing effect |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |