JP3322286B2 - Washing soap - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a mold cleaning agent,
It is suitably used for disinfecting and antibacterial of molds such as general households, public facilities, and industrial equipment.

[0002]

2. Description of the Related Art In recent years, mold has been increasing in rooms such as homes, offices, and schools due to the completeness of heating facilities and airtightness of rooms. The occurrence of mold is not preferable from the viewpoint of aesthetics and health. In order to prevent mold, it is necessary to keep cold, dry and clean.

However, humid bathrooms and toilets,
Molds are likely to occur in washrooms, electronic devices such as refrigerators, ovens, and mixers, tatami mats, carpets, and the like.
In addition, mold is generated on various devices such as stirrers, kneading machines, filling machines, underground cables, medical equipment, etc.
It causes obstacles such as infection and electric leakage. In addition, recently, there have been many reports of the presence of xerophilic molds that grow even under dry conditions, and there are very many cases of allergic symptoms caused by mold development.

[0004] In addition, with increasing interest in environmental problems, interest in wastewater causing environmental pollution has also increased, and a more environmentally friendly one has been demanded. The rough work of daily housework is also a big problem for housewives.

[0005]

Heretofore, as a commercially available agent for removing and preventing such mold, a strongly alkaline solution using hypochlorite and a strongly acidic solution using hydrochloric acid have been commercially available. . All of these agents have a certain effect on mold removal, but are extremely dangerous because they are strong alkali (pH 12 or higher) or strong acid (pH 3 or lower). There is a risk of blindness.

Further, chlorine-based fungicides have a strong odor,
Irritation to the throat, strong irritation to the eyes, and it is necessary to work with adequate ventilation. Moreover, chronic use of a fungicide having a strong physicochemical action may cause chronic respiratory disorders.

[0007] In order to solve such problems, the present applicant has already provided a fungicide containing lactic acid (Japanese Patent Application Laid-Open No. 5-908). And the consideration for the amount of chlorine gas generated was insufficient.

[0008] Furthermore, although consideration has been given to the human body and the environment at present, there is still a strong awareness of priority on effects, and there is not enough room for consumers to choose. In recent years when environmental problems have become social problems, not only effects but also environmental friendliness have been pursued at the same time.

Therefore, the present invention provides a cleaning agent which can be used easily and usually has a bactericidal / antibacterial (fungicidal / antifungal) effect, is environmentally friendly, and has little danger to the human body. It is intended to provide an agent.

[0010]

Means for Solving the Problems As a result of intensive studies, the present inventors have found that if the concentration of lactic acid or a lactic acid derivative is suppressed to 3% or less and the pH is within a range of 3 or more and less than 5, bactericidal fungi can be sterilized. The present inventors have found that it is excellent in antibacterial action and that it can prevent the chlorine gas generation concentration from exceeding 1 ppm in a chlorine gas generation test according to the Household Goods Quality Labeling Law, and has accomplished the present invention.

That is, according to the present invention, the concentration is 0.1 to 3%.
A mold detergent containing the following lactic acid and having a chlorine gas generation concentration of not more than 1 ppm in a chlorine gas generation test according to the Household Goods Quality Labeling Law having a pH of 3 to less than 5.

The lactic acid used in the present invention is D-lactic acid, L-lactic acid.
Any of lactic acid and D, L-lactic acid may be used. In particular, L-lactic acid obtained by the fermentation method is metabolized in the human body and is highly safe and preferable. In order to use such lactic acid as a detergent, it is preferable to use lactic acid as an aqueous solution. The aqueous solution of lactic acid is 0.1-3%. If the concentration is lower than this range, a sufficient antifungal effect cannot be obtained. On the other hand, when the concentration is higher than this range as shown in Table 1, it exceeds 1 ppm, which is a limit to which a person can endure for a long time in a chlorine gas generation test specified in the Household Goods Quality Labeling Law.

[0013]

[Table 1] In addition, Table 1 was tested by the "chlorine gas generation test (acid type)" in the household goods quality labeling method, and the test solution was an aqueous solution having an L-lactic acid concentration of 7, 5, 4, 3%.
It was adjusted with caustic soda to pH 3.5.

Lactic acid, as used as a food additive, is an extremely safe substance, and utilizes its bactericidal, antibacterial (fungicidal and antifungal) action and dirt decomposing action. I do.

Lactic acid is an organic acid having a small dissociation constant after acetic acid. Particularly, L-lactic acid, an optically active substance, is an acid having high biosafety which is also used in infusion and is metabolized in the body, and has a low vapor pressure and a bad odor There is no. Tables 2 and 3 show the results of the safety test of the detergent using the fermented L-lactic acid, and Table 4 shows the results of the fungicide test.

<Safety / eye irritation test> [Test animals] Japanese white male rabbits were purchased from Japan SLC, Inc., and were preliminarily bred for at least one week to confirm that there was no abnormality in their health. Nine were used for the test. Test animals were housed individually in FRP cages and were kept at room temperature 2
They were bred in a breeding room set at 2 ± 2 ° C. and a lighting time of 12 hours / day. As a feed, a solid feed for rabbits (CR-3, CLEA Japan) was supplied, and tap water was freely taken as drinking water.

[Test Method] Both eyes of each test animal were examined using sodium fluorescein within 24 hours before the start of the test to confirm that there was no abnormality.

After measuring the body weight, the test animals were group I (6 animals).
Each test animal was divided into group II (3 animals), and 0.1 ml of the specimen was instilled into the conjunctival sac of each eye. The other eye served as an untreated control. Thereafter, Group I was a non-washing group, and Group II was washed for 30 minutes using purified water 30 seconds later. Observation 24, 48, 7 after instillation
The examination was performed on the cornea, iris and conjunctiva using a slit lamp at 2 hours and 4 and 7 days, and scored according to the scoring standard.
Further, 24 hours after the instillation and 7 days after the end of the observation, the presence or absence of corneal damage was observed in more detail using sodium fluorescein.

From the total score of each test animal, an average value was calculated for each of the groups I and II. From this value, Table 2-1
Based on the evaluation criteria shown in (1), the eye irritation of the sample was evaluated.

[Test results]

[Table 2] << Safety / Primary skin irritation test >> [Test animals] Japanese white male rabbits were purchased from Japan SLC Co., Ltd., and were bred for at least one week to confirm that there was no abnormality in health. The animals were used for the test. Test animals were housed individually in FRP gauges and were kept at room temperature 2
They were bred in a breeding room set at 2 ± 2 ° C. and a lighting time of 12 hours / day. As a feed, a solid feed for rabbits (CR-3, CLEA Japan) was supplied, and tap water was automatically taken as drinking water.

[Test Method] The hair on the back of the trunk of each test animal was shaved about 24 hours before the test.

Each test animal has an area of about 6 cm ² and 4
Two places were set, and two of them were scratched on the keratinized layer so as not to reach the dermis (injured skin), and the other two were left untreated (intact skin).

In a gauze patch cut into about 2 cm × 3 cm,
A test sample (0.5 ml) was uniformly applied, applied to each of the injured and intact skin, and then fixed with an adhesive plaster (JP). Also, 3M-Bl so that the patch is in contact with the skin
It was held with enderm surgical tape. The remaining intact and intact skin served as controls.

The exposure time was 4 hours, after which the patch was removed and the exposed surface was wiped with distilled water. 1, 2 after removal
Observations were made at 4, 48, and 72 hours, and stimulus responses were scored according to Table 3-1.

[Test results]

[Table 3] << Mold Kill Test >> [Test Method] A sample was placed in a test tube having an inner diameter of 26 mm by 10 ml, and a spore suspension (10 ⁶ ) of each test tube mold prepared in advance was prepared.
Pcs / ml) into each test tube. This test tube is placed in a thermostat at 20 ° C., and is operated for a predetermined time.
1 ml of the test solution for 10 minutes, 30 minutes and 2 hours
Then, dilute with a 0.005% aerosol OT sterilizing solution up to 10 ⁴ times. 0.1 from the working test solution and each dilution test solution
Aseptically remove and inoculate a potato dextrose agar plate. The potato dextrose agar plate is cultured at 27 ° C. for 7 days, and the number of molds that have developed is counted to determine the number of molds per 1 ml of the sample.

[Test Results] Table 4 shows the bactericidal rate against each mold and fungus.

[0027]

[Table 4] From the results shown in Tables 2 and 3, the safety for the human body is high unless the detergent containing lactic acid as a main component is a strongly irritating surfactant or the like.

As can be seen from Table 4, the detergent containing lactic acid has a high fungicidal effect. Lactic acid has a fungicidal effect, as has been used for preserving foods since ancient times. This is presumably because undissociated lactic acid enters the mold cells and destroys the metabolic system to kill the mold, or the lactic acid bacteria themselves produce a substance having an antibacterial action.

The cleaning agent of the present invention may contain, in addition to lactic acid, a surfactant, an organic acid such as citric acid, a solvent and an alcohol. By adding a surfactant, lactic acid sterilization and
Can improve antibacterial (fungicidal and antifungal) effects,
Citric acid can also have a chelating effect.

Further, by adding a solvent / alcohol, the dissolving power of dirt is further improved, and the sterilizing / antibacterial effect is improved. However, when alcohol is added,
Alcohol addition is limited to 1% or less because of the effect of increasing the amount of chlorine gas generated.

The typical composition of the detergent of the present invention is L-lactic acid 0.1 to 3%, surfactant 0.1 to 10%.
%, PH 3-5. It has a bactericidal and antibacterial (fungicidal and antifungal) properties with lactic acid, does not generate chlorine gas, and is characterized by a weakly acidic and human-friendly cleaning agent.

[0032]

When the conventional chlorine-based and strongly acidic ones are mixed and used with acidic and chlorine-based ones respectively, a large amount of chlorine gas harmful to the human body is generated, but the cleaning agent of the present invention is used by mixing with chlorine-based ones. However, not much chlorine gas is derived. In the chlorine gas generation test of the Household Goods Quality Labeling Law, it does not exceed 1 ppm, which is the labeling standard for “mixable danger”. The cleaning agent of the present invention adheres to the surface of a substrate, and helps to improve the cleaning power by a physical action.

[0033]

EXAMPLES The present invention will be described more specifically based on examples.

3 parts by weight of L-lactic acid, 3 parts by weight of a surfactant,
2 parts by weight of the solvent and 92 parts by weight of water were mixed to prepare a detergent. When this cleaning agent was used in a bathroom, the scale was well removed, and the chlorine gas generation test according to the Household Goods Quality Labeling Law did not exceed 1 ppm.

[0035]

EFFECT OF THE INVENTION The cleaning agent of the present invention does not exceed 1 ppm which is a standard for "mixing danger" in the chlorine gas generation test of the Household Goods Quality Labeling Law, and is safer for humans and the environment. Becomes

Further, it has an effect of an excellent cleaning agent having sterilization and antibacterial properties.

──────────────────────────────────────────────────続 き Continuation of the front page (56) References JP-A-2-247299 (JP, A) JP-A-64-71805 (JP, A) JP-A-59-164398 (JP, A) JP-A-2- 298599 (JP, A) JP-A-5-908 (JP, A) JP-A-7-197090 (JP, A) (58) Fields investigated (Int. Cl. ⁷ , DB name) C11D 3/20 C11D 7 / 26 A01N 25/30 A01N 37/36

Claims (1)

(57) [Claims] 1. A lactic acid having a concentration of 0.1 to 3% or less,
A mold cleaner having a pH of 3 or more and less than 5 and a chlorine gas generation concentration of not more than 1 ppm in a chlorine gas generation test according to the Household Goods Quality Labeling Law.