CN115916411A - 用于组织处理的装置和方法 - Google Patents

用于组织处理的装置和方法 Download PDF

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Publication number
CN115916411A
CN115916411A CN202180040209.9A CN202180040209A CN115916411A CN 115916411 A CN115916411 A CN 115916411A CN 202180040209 A CN202180040209 A CN 202180040209A CN 115916411 A CN115916411 A CN 115916411A
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CN
China
Prior art keywords
tissue
chamber
rotating blade
drive shaft
screen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180040209.9A
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English (en)
Chinese (zh)
Inventor
卡米洛·里科尔迪
贾科莫·兰佐尼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Miami filed Critical University of Miami
Publication of CN115916411A publication Critical patent/CN115916411A/zh
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C18/00—Disintegrating by knives or other cutting or tearing members which chop material into fragments
    • B02C18/06—Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives
    • B02C18/08—Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers
    • B02C18/10—Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers with drive arranged above container
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00—Other disintegrating devices or methods
    • B02C19/20—Disintegrating by grating
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Sampling And Sample Adjustment (AREA)
CN202180040209.9A 2020-04-06 2021-04-06 用于组织处理的装置和方法 Pending CN115916411A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063005900P 2020-04-06 2020-04-06
US63/005,900 2020-04-06
PCT/US2021/025941 WO2021207177A1 (en) 2020-04-06 2021-04-06 Device and method for tissue processing

Publications (1)

Publication Number Publication Date
CN115916411A true CN115916411A (zh) 2023-04-04

Family

ID=78023884

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180040209.9A Pending CN115916411A (zh) 2020-04-06 2021-04-06 用于组织处理的装置和方法

Country Status (9)

Country Link
US (1) US20230160791A1 (https=)
EP (1) EP4132716A4 (https=)
JP (1) JP2023521520A (https=)
KR (1) KR20230022838A (https=)
CN (1) CN115916411A (https=)
AU (1) AU2021251750A1 (https=)
BR (1) BR112022020154A2 (https=)
CA (1) CA3188847A1 (https=)
WO (1) WO2021207177A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102683103B1 (ko) * 2023-11-30 2024-07-09 디에스메카 주식회사 비접촉식 생체시료 조직분리 챔버의 원격 통합관리 시스템

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731199A (en) * 1993-09-28 1998-03-24 Roggero; Gianmarco Mechanical triturator for biological material
CN102382757A (zh) * 2010-08-27 2012-03-21 日本光电工业株式会社 细胞离析装置
CN205557788U (zh) * 2016-04-18 2016-09-07 象山逸迪电子科技有限公司 一种具有粉碎功能的地漏
CN107107068A (zh) * 2014-12-15 2017-08-29 人类脑波责任有限公司 生物材料的分解装置和相应的制造方法及制备细胞悬浮液和组织微移植物的方法
CN109843417A (zh) * 2016-08-21 2019-06-04 艾德瓦生物技术股份有限公司 生物反应器及其使用方法
CN110643495A (zh) * 2019-10-31 2020-01-03 北京伟力新世纪科技发展股份有限公司 一种细胞悬浮液制备装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19912798C1 (de) * 1999-03-10 2000-02-17 Andreas Jordan Verfahren zur Kultivierung von Krebszellen aus Humangewebe und Vorrichtung zur Aufbereitung von Gewebeproben
JP5970293B2 (ja) * 2012-08-21 2016-08-17 シスメックス株式会社 破砕処理装置
US8871159B1 (en) * 2013-12-17 2014-10-28 Christian Apfel Preparation of cells, cell aggregates and tissue fragments
CN209081893U (zh) * 2018-09-27 2019-07-09 瑞智康生物技术（昆山）有限公司 一种快速更换研磨杵的手持式组织研磨器

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731199A (en) * 1993-09-28 1998-03-24 Roggero; Gianmarco Mechanical triturator for biological material
CN102382757A (zh) * 2010-08-27 2012-03-21 日本光电工业株式会社 细胞离析装置
CN107107068A (zh) * 2014-12-15 2017-08-29 人类脑波责任有限公司 生物材料的分解装置和相应的制造方法及制备细胞悬浮液和组织微移植物的方法
CN205557788U (zh) * 2016-04-18 2016-09-07 象山逸迪电子科技有限公司 一种具有粉碎功能的地漏
CN109843417A (zh) * 2016-08-21 2019-06-04 艾德瓦生物技术股份有限公司 生物反应器及其使用方法
CN110643495A (zh) * 2019-10-31 2020-01-03 北京伟力新世纪科技发展股份有限公司 一种细胞悬浮液制备装置

Also Published As

Publication number Publication date
AU2021251750A1 (en) 2022-11-03
EP4132716A4 (en) 2024-07-17
KR20230022838A (ko) 2023-02-16
US20230160791A1 (en) 2023-05-25
WO2021207177A1 (en) 2021-10-14
EP4132716A1 (en) 2023-02-15
CA3188847A1 (en) 2021-10-14
BR112022020154A2 (pt) 2022-12-13
JP2023521520A (ja) 2023-05-24

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