CA3188847A1 - Device and method for tissue processing - Google Patents

Device and method for tissue processing

Info

Publication number
CA3188847A1
CA3188847A1 CA3188847A CA3188847A CA3188847A1 CA 3188847 A1 CA3188847 A1 CA 3188847A1 CA 3188847 A CA3188847 A CA 3188847A CA 3188847 A CA3188847 A CA 3188847A CA 3188847 A1 CA3188847 A1 CA 3188847A1
Authority
CA
Canada
Prior art keywords
tissue
chamber
rotary blade
processing device
screen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3188847A
Other languages
English (en)
French (fr)
Inventor
Giacomo LANZONI
Camillo Ricordi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Miami
Original Assignee
University of Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Miami filed Critical University of Miami
Publication of CA3188847A1 publication Critical patent/CA3188847A1/en
Pending legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C18/00Disintegrating by knives or other cutting or tearing members which chop material into fragments
    • B02C18/06Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives
    • B02C18/08Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers
    • B02C18/10Disintegrating by knives or other cutting or tearing members which chop material into fragments with rotating knives within vertical containers with drive arranged above container
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/20Disintegrating by grating
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/02Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873Cutting or cleaving

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Food Science & Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Materials For Medical Uses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Surgical Instruments (AREA)
  • Sampling And Sample Adjustment (AREA)
CA3188847A 2020-04-06 2021-04-06 Device and method for tissue processing Pending CA3188847A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063005900P 2020-04-06 2020-04-06
US63/005,900 2020-04-06
PCT/US2021/025941 WO2021207177A1 (en) 2020-04-06 2021-04-06 Device and method for tissue processing

Publications (1)

Publication Number Publication Date
CA3188847A1 true CA3188847A1 (en) 2021-10-14

Family

ID=78023884

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3188847A Pending CA3188847A1 (en) 2020-04-06 2021-04-06 Device and method for tissue processing

Country Status (9)

Country Link
US (1) US20230160791A1 (https=)
EP (1) EP4132716A4 (https=)
JP (1) JP2023521520A (https=)
KR (1) KR20230022838A (https=)
CN (1) CN115916411A (https=)
AU (1) AU2021251750A1 (https=)
BR (1) BR112022020154A2 (https=)
CA (1) CA3188847A1 (https=)
WO (1) WO2021207177A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102683103B1 (ko) * 2023-11-30 2024-07-09 디에스메카 주식회사 비접촉식 생체시료 조직분리 챔버의 원격 통합관리 시스템

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1260682B (it) * 1993-09-28 1996-04-22 Consult T S S N C Di Roggero G Dispositivo trituratore meccanico di materiale biologico
DE19912798C1 (de) * 1999-03-10 2000-02-17 Andreas Jordan Verfahren zur Kultivierung von Krebszellen aus Humangewebe und Vorrichtung zur Aufbereitung von Gewebeproben
JP5837742B2 (ja) * 2010-08-27 2015-12-24 学校法人東京女子医科大学 細胞単離装置
JP5970293B2 (ja) * 2012-08-21 2016-08-17 シスメックス株式会社 破砕処理装置
US8871159B1 (en) * 2013-12-17 2014-10-28 Christian Apfel Preparation of cells, cell aggregates and tissue fragments
KR102565995B1 (ko) * 2014-12-15 2023-08-10 휴먼 브레인 웨이브 에스.알.엘. 생체 시료의 분해 장치 및 대응되는 제조 방법과 세포 현탁액 및 조직 미세이식편의 준비 방법
CN205557788U (zh) * 2016-04-18 2016-09-07 象山逸迪电子科技有限公司 一种具有粉碎功能的地漏
CA3034452A1 (en) * 2016-08-21 2018-03-01 Adva Biotechnology Ltd. Bioreactor and methods of use thereof
CN209081893U (zh) * 2018-09-27 2019-07-09 瑞智康生物技术(昆山)有限公司 一种快速更换研磨杵的手持式组织研磨器
CN110643495A (zh) * 2019-10-31 2020-01-03 北京伟力新世纪科技发展股份有限公司 一种细胞悬浮液制备装置

Also Published As

Publication number Publication date
AU2021251750A1 (en) 2022-11-03
EP4132716A4 (en) 2024-07-17
KR20230022838A (ko) 2023-02-16
CN115916411A (zh) 2023-04-04
US20230160791A1 (en) 2023-05-25
WO2021207177A1 (en) 2021-10-14
EP4132716A1 (en) 2023-02-15
BR112022020154A2 (pt) 2022-12-13
JP2023521520A (ja) 2023-05-24

Similar Documents

Publication Publication Date Title
CN107921182B (zh) 用于分离基质血管部分的机械仪器和方法
KR102143286B1 (ko) 인간 및 동물 조직으로부터 세포 분획을 단리하기 위한 장치 및 그 사용 방법
US12135262B2 (en) Comminuting device of biological material and relative method for comminuting and cellular preparations
CN111607495A (zh) 一种肿瘤类器官制备方法及其装置和应用
US20230160791A1 (en) Device and method for tissue processing
Frye et al. Three-dimensional adipose tissue model using low shear bioreactors
EP2502986B1 (en) A cartilage cell processing system
TW201512395A (zh) 體外快速切碎脂肪組織以分離活細胞之方法
CN118371048A (zh) 一种肠道菌群的分离浓缩装置及菌群制备方法
US20220275316A1 (en) Container for separating live cells
KR101440754B1 (ko) 세포 농축형 분리기 및 분리 방법
RU173796U1 (ru) Устройство для фракционирования жировой ткани и выделения из нее стромально-васкулярной фракции для применения в регенеративной медицине
CN222556938U (zh) 用于从组织中分离或分出细胞或细胞群的设备
CN112553161A (zh) 一种卵巢癌类器官扩增的方法
RU2749986C1 (ru) Способ выделения кардиомиоцитов из ткани сердца человека
US11535822B2 (en) Device for isolating stem cells from fetal tissues
WO2018160096A1 (ru) Устройство для фракционирования жировой ткани и выделения из нее стромально-васкулярной фракции для применения в регенеративной медицине
EP4735181A1 (en) Improved crushing device in an isolated environment
WO2023209039A2 (en) Tissue structure isolation using a micro-cutting device and uses of resulting micro-cubes of tissue
JP2023533649A (ja) 生体材料を処理する装置
Bahnemann et al. Ultrasound as an effective method to isolate intact mitochondria from CHO cells for physiological studies
HK1153382A (en) A method of making a soft tissue filter and a method of making an adipose tissue implant
HK1153382B (en) A method of making a soft tissue filter and a method of making an adipose tissue implant

Legal Events

Date Code Title Description
D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED

Effective date: 20250311

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20250317

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - STANDARD

Year of fee payment: 4

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250328

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-1-1-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20250328

D00 Search and/or examination requested or commenced

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20250407

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT

Effective date: 20250501

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-2-2-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20250515