CN115867805A - 用于快速检测生物样品中的目标分析物的装置和方法 - Google Patents

用于快速检测生物样品中的目标分析物的装置和方法 Download PDF

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Publication number
CN115867805A
CN115867805A CN202180039103.7A CN202180039103A CN115867805A CN 115867805 A CN115867805 A CN 115867805A CN 202180039103 A CN202180039103 A CN 202180039103A CN 115867805 A CN115867805 A CN 115867805A
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optionally
reporter
substrate
membrane
vitrified
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Chinese (zh)
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P·S·莫汉提
Z·王
S·达斯
Y·泰维纳
A·雷迪
P·乔西
S·阿姆勒
J·曼特拉
L·布朗萨特
M·雷兹拉夫
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Upkala
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nanotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202180039103.7A 2020-03-31 2021-03-31 用于快速检测生物样品中的目标分析物的装置和方法 Pending CN115867805A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063002873P 2020-03-31 2020-03-31
US63/002,873 2020-03-31
US202063051668P 2020-07-14 2020-07-14
US63/051,668 2020-07-14
PCT/US2021/025115 WO2021202685A1 (en) 2020-03-31 2021-03-31 Device and methods for rapid detection of target analytes in a biological sample

Publications (1)

Publication Number Publication Date
CN115867805A true CN115867805A (zh) 2023-03-28

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US (1) US20230104815A1 (https=)
EP (1) EP4127720A4 (https=)
JP (1) JP7839740B6 (https=)
KR (1) KR20220161465A (https=)
CN (1) CN115867805A (https=)
CA (1) CA3173418A1 (https=)
WO (1) WO2021202685A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI790518B (zh) * 2020-12-25 2023-01-21 國立陽明交通大學 病毒收集基體
WO2023100567A1 (ja) * 2021-12-02 2023-06-08 株式会社デンソー 分析方法
US20230400459A1 (en) * 2022-06-09 2023-12-14 Hero Scientific Ltd. Gargle specimen sampling
US12416633B2 (en) * 2022-12-27 2025-09-16 Princeton Biochemicals Method and system for exposing hidden or masked antigenic sites of viral specimens present in biosamples using a home-based COVID-19 rapid lateral flow immunoassay test

Citations (8)

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CN1081765A (zh) * 1992-03-05 1994-02-09 曼海姆泊灵格股份公司 用于测定血红蛋白衍生物的免疫方法
US5434051A (en) * 1991-07-26 1995-07-18 E. I. Du Pont De Nemours And Company Assay with signal detection in the presence of a suspended solid support
CN1340710A (zh) * 2000-08-29 2002-03-20 上海正源生命技术有限公司 应用室温玻化技生产室温稳定的免疫层析试条
CN1902489A (zh) * 2003-06-06 2007-01-24 优势诊疗技术公司 对样品中分析物的诊断试验
CN203786122U (zh) * 2014-04-16 2014-08-20 普生（天津）科技有限公司 一种测量精度高的瘦肉精检测试纸卡
JP2017116537A (ja) * 2015-12-18 2017-06-29 株式会社リコー 検査装置用熱転写媒体、検査装置及びその製造方法、並びに検査キット
CN207816989U (zh) * 2017-09-30 2018-09-04 山东爱维德生物科技有限公司 一种多功能胶体金试剂盒
US10433540B2 (en) * 2014-06-09 2019-10-08 Somnio Global Holdings, Llc Capillary assisted vitrification processes and devices

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US5415994A (en) * 1993-08-02 1995-05-16 Quidel Corporation Lateral flow medical diagnostic assay device with sample extraction means
PT924991E (pt) * 1996-07-02 2002-02-28 Bbi Bioseq Inc Ligacao mediada por pressao de complexos biomoleculares
US8003407B2 (en) * 2004-07-29 2011-08-23 Relia Diagnostic Systems, Llc Lateral flow system and assay
CN101326441B (zh) * 2005-12-08 2013-04-10 可瑞斯生物概念公司 用于快速诊断的试验装置
US20130196310A1 (en) * 2008-05-20 2013-08-01 Rapid Pathogen Screening, Inc. Method and Device for Combined Detection of Viral and Bacterial Infections
JP2014521061A (ja) * 2011-06-30 2014-08-25 コーニンクレッカ フィリップス エヌ ヴェ 乾燥タンパク質との反応チャンバの調製
US20130309656A1 (en) 2012-05-17 2013-11-21 David C. Davis Antibody detection method and device for a saliva sample from a non-human animal
RU2668534C1 (ru) * 2017-07-18 2018-10-01 Общество с ограниченной ответственностью "ДРД" Диагностический набор реагентов для выявления хронических патологий мозга ишемического генеза
JP7796660B2 (ja) * 2020-03-09 2026-01-09 エフ． ホフマン－ラ ロシュ アーゲー 重症急性呼吸器症候群コロナウイルス２（ｓａｒｓ－ｃｏｖ－２）、インフルエンザａ及びインフルエンザｂを検出するための組成物及び方法

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434051A (en) * 1991-07-26 1995-07-18 E. I. Du Pont De Nemours And Company Assay with signal detection in the presence of a suspended solid support
CN1081765A (zh) * 1992-03-05 1994-02-09 曼海姆泊灵格股份公司 用于测定血红蛋白衍生物的免疫方法
CN1340710A (zh) * 2000-08-29 2002-03-20 上海正源生命技术有限公司 应用室温玻化技生产室温稳定的免疫层析试条
CN1902489A (zh) * 2003-06-06 2007-01-24 优势诊疗技术公司 对样品中分析物的诊断试验
CN203786122U (zh) * 2014-04-16 2014-08-20 普生（天津）科技有限公司 一种测量精度高的瘦肉精检测试纸卡
US10433540B2 (en) * 2014-06-09 2019-10-08 Somnio Global Holdings, Llc Capillary assisted vitrification processes and devices
JP2017116537A (ja) * 2015-12-18 2017-06-29 株式会社リコー 検査装置用熱転写媒体、検査装置及びその製造方法、並びに検査キット
CN207816989U (zh) * 2017-09-30 2018-09-04 山东爱维德生物科技有限公司 一种多功能胶体金试剂盒

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KR20220161465A (ko) 2022-12-06
WO2021202685A1 (en) 2021-10-07
JP7839740B6 (ja) 2026-04-24
JP2023520482A (ja) 2023-05-17
JP7839740B2 (ja) 2026-04-02
CA3173418A1 (en) 2021-10-07
EP4127720A4 (en) 2024-05-01
US20230104815A1 (en) 2023-04-06
EP4127720A1 (en) 2023-02-08

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