CN115804805A - Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag - Google Patents

Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag Download PDF

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Publication number
CN115804805A
CN115804805A CN202211702614.5A CN202211702614A CN115804805A CN 115804805 A CN115804805 A CN 115804805A CN 202211702614 A CN202211702614 A CN 202211702614A CN 115804805 A CN115804805 A CN 115804805A
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traditional chinese
chinese medicine
ankylosing spondylitis
treating ankylosing
external
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CN115804805B (en
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黄旦
刘健
汪元
张皖东
曹云祥
万磊
纵瑞凯
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First Affiliated Hospital of AHUTCM
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First Affiliated Hospital of AHUTCM
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A traditional Chinese medicine compound composition for treating ankylosing spondylitis and an external medicine bag belong to the technical field of traditional Chinese medicine compound for treating ankylosing spondylitis, and comprise 15-25g of parasitic loranthus, 15-25g of radix achyranthis bidentatae, 5-15g of cassia twig, 5-20g of lycopodium clavatum, 5-15g of safflower, 5-15g of folium artemisiae argyi, 5-20g of garden balsam stem, 10-15g of radix aconiti lateralis preparata, 5-15g of radix aconiti, 10g of asarum, 5-15g of fructus liquidambaris, 5-15g of borneol, 10-15g of cortex acanthopanacis, 10-15g of wooly datchmanspipe herb, 5-10g of fructus polygoni orientalis and 25-35g of actinolite. The traditional Chinese medicine composition is prepared according to the principle of monarch, minister, assistant and guide components, and has the effects of tonifying kidney, strengthening governor meridian, warming and activating meridian, and promoting blood circulation to arrest pain. Meanwhile, the external medicine bag can penetrate into the human body through the channels and collaterals on the body surface of the human body, thereby playing a better treatment role.

Description

Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compound for treating ankylosing spondylitis, and particularly relates to a traditional Chinese medicine compound composition for treating ankylosing spondylitis and an external medicine bag.
Background
Ankylosing Spondylitis (AS) is a common inflammatory rheumatic disease that affects the central axis skeleton, causing characteristic inflammatory back pain, which can lead to structural and functional disorders and a decrease in quality of life. The incidence of AS in chinese populations is similar to that of white european population, about 0.24%. About 4% of patients lose part of their labor capacity 5 years after the onset of AS, and about 50% 45 years after the onset of AS. The pathogenesis of AS is unclear and may be related to genetics, infection, environment, immunity, etc. The key to the treatment is to relieve the inflammatory symptoms of AS patients AS soon AS possible, relieve pain, control disease activities, delay the progress of diseases and reduce teratogenic and disabling injuries of the patients caused by the diseases. However, the existing AS treatment medicines comprise non-steroidal anti-inflammatory drugs for improving the disease condition, immunosuppressants, antirheumatics, glucocorticoids and the like, and the long-term administration has large side effect, and causes adverse reactions such AS intolerance and influence on the liver and kidney functions of the gastrointestinal tract, thereby leading to heavy physical and psychological burdens of patients.
The traditional Chinese medicine can effectively improve the clinical symptoms of AS patients and reduce toxic and side effects, thereby further improving the life quality of the patients. Chinese patent application CN103893427A discloses a Chinese medicinal composition for treating ankylosing spondylitis and its preparation method, the composition is prepared from the following raw materials: kudzu root, chinese angelica, white paeony root, prepared rehmannia root, epimedium herb, deerhorn glue, chinese wolfberry, heterophylly falsestarwort root, incised notopterygium rhizome, doubleteeth pubescent angelica root, red paeony root, common macrocarpium fruit, chinese taxillus twig, himalayan teasel root, cassia twig, danshen root, suberect spatholobus stem, chinese wolfberry fruit, glossy privet fruit, desertliving cistanche, twotooth achyranthes root, fortune's drynaria rhizome, east Asian tree fern rhizome, eucommia bark, common curculigo rhizome, tuber fleeceflower root, medicinal indianmulberry root, glossy privet fruit, figwort root, costustoot, szechuan lovage rhizome, indian buead, large-leaved gentian, divaricate saposhnikovia root, medicinal cyathula root, manchurian wildginger, cassia twig, clematis root, prepared common monkshood mother root, prepared myrrh, prepared frankincense, liquoric root and pangolin. The traditional Chinese medicine composition has the advantages of safe propaganda and clinical application, no internal organ stimulation during oral administration, convenience in preparation and administration, guarantee of the purity of the medicine, convenience in storage, obvious curative effect, multiple absorption of effective components, good performance of medicine property, treatment of both symptoms and root causes, and total effective rate of 97%.
Chinese patent application CN106619988A discloses a traditional Chinese medicine foot-soaking powder for treating lumbocrural pain and a preparation method thereof, and the formula comprises: cassia twig, ledebouriella root, chinese mugwort leaf, schizonepeta tenuifolia, notopterygium root, pubescent angelica root, loranthus mulberry mistletoe, acanthopanax bark and safflower each 20g, eucommia bark, chinese angelica root, cinnamomum cassia, prepared rhizome of rehmannia, dipsacus root, buck grass, speranskia herb, dahurian angelica root, mulberry twig, sappan wood and Clematis chinensis each 30g, raw frankincense, raw myrrh, cyathula root and achyranthes root each 16g are added. The formulation of the foot bath powder is foot bath powder, and the foot bath powder has good treatment effect on lumbocrural pain.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine compound composition and an external medicine bag for treating ankylosing spondylitis, which are prepared according to the principle of monarch, minister, assistant and guide, and have the effects of tonifying kidney, strengthening governor vessel, warming channels, dredging collaterals, promoting blood circulation and relieving pain. Meanwhile, the external medicine bag can penetrate into the human body through the channels and collaterals on the body surface of the human body, thereby playing a better treatment role.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows:
a traditional Chinese medicine compound composition for treating ankylosing spondylitis is prepared from the following traditional Chinese medicine raw materials in parts by weight:
15-25g of parasitic loranthus, 15-25g of radix achyranthis bidentatae, 5-15g of cassia twig, 5-20g of lycopodium clavatum, 5-15g of safflower, 5-15g of folium artemisiae argyi, 5-20g of garden balsam stem, 10-15g of aconite accessory piece, 5-15g of radix aconiti, 10g of asarum, 5-15g of beautiful sweetgum fruit, 5-15g of borneol, 10-15g of cortex acanthopanacis, 10-15g of wooly datchmanspipe herb, 5-10g of fructus polygoni orientalis and 25-35g of actinolite.
The treatment principle of the traditional Chinese medicine compound composition is as follows: tonifying kidney, strengthening Du channel, warming and activating meridian, promoting blood circulation, and relieving pain. The ankylosing spondylitis patients have the main symptoms of waist and back pain, belong to the category of arthralgia syndrome in traditional Chinese medicine, and have the main pathogenesis of obstruction causing pain, and the patients have the defects of spleen and kidney deficiency, insufficient vital qi, easy invasion of exogenous factors, obstruction of qi and blood circulation, stasis caused by transformation and obstruction causing pain. Therefore, in the compound composition, the loranthus parasiticus and the radix achyranthis bidentatae are monarch drugs, can tonify liver and kidney and dispel wind-damp. Cassia twig, radix aconiti lateralis preparata, asarum, folium artemisiae argyi, radix aconiti, cortex acanthopanacis, fructus liquidambaris, berba aristolochiae mollissimae, speranskia herb and lycopodium clavatum are used as ministerial drugs for dispelling wind-damp and stopping arthralgia. Safflower and fructus polygoni orientalis have the functions of promoting blood circulation, removing blood stasis and relieving pain, actinolite tonifies the kidney and dispels the cold, and are used as adjuvant drugs, borneol is pungent and thorough in flavor, clears the orifices and relieves the pain, and white spirit activates the blood circulation and channels to guide the drugs to the disease sites. The external treatment method is that the external medicine bag penetrates into the human body through the channels and collaterals on the surface of the human body to play a role in treatment, so that the external medicine bag is better favorable for treating the ankylosing spondylitis.
As a preferred technical scheme of the traditional Chinese medicine compound composition for treating ankylosing spondylitis, the traditional Chinese medicine compound composition is prepared from the following traditional Chinese medicine raw materials in parts by weight:
20g of parasitic loranthus, 20g of radix achyranthis bidentatae, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of folium artemisiae argyi, 10g of garden balsam stem, 10g of radix aconiti lateralis preparata, 10g of radix aconiti, 10g of asarum, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of wooly datchmanspipe herb, 10g of fructus polygoni orientalis and 30g of actinolite.
The invention also provides an external medicine bag prepared by the traditional Chinese medicine compound composition, which is prepared by crushing the traditional Chinese medicines, spraying a proper amount of white spirit into the medicine powder, uniformly mixing the medicine powder and putting the medicine powder into a cloth bag.
The traditional Chinese medicine compound composition can be used for treating ankylosing spondylitis and has a good treatment effect. The prepared external medicine bag can penetrate into the human body through the channels and collaterals on the surface of the human body, thereby playing a better therapeutic role.
Detailed Description
The present invention will be described in further detail with reference to the following examples and accompanying drawings.
Example 1
The externally applied medicine package for treating ankylosing spondylitis:
the compound composition is as follows: 20g of parasitic loranthus, 20g of radix achyranthis bidentatae, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of folium artemisiae argyi, 10g of garden balsam stem, 10g of radix aconiti lateralis preparata, 10g of radix aconiti, 10g of asarum, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of wooly datchmanspipe herb, 10g of fructus polygoni orientalis and 30g of actinolite.
The preparation method comprises the following steps: pulverizing the above Chinese medicinal materials, spraying 200g Chinese liquor into the medicinal powder, mixing the medicinal powder uniformly, and placing into a cloth bag to obtain the topical medicinal bag.
Before use, the product is placed into a microwave oven to be heated for 3 minutes and then placed on the back of a patient with ankylosing spondylitis for hot compress.
Example 2
Statistics of therapeutic effects
60 patients with ankylosing spondylitis (outpatients of first subsidiary hospital of university of traditional Chinese medicine in Anhui province) were treated with the external use medicine package prepared according to the method of example 1; 56 men and 4 women with the age of 20-28 years and the average age of 24 years. The course of disease is 0.5-5 years. The clinical manifestations are evaluation criteria of curative effects such as low back pain, stiffness, limited movement and the like:
(1) And curing: after the external medicine bag is used for treating 2 courses of treatment, the pain symptom of the patient disappears, and the joint can move normally;
(2) And the effectiveness is as follows: after the external medicine bag is used for treating 2 courses of treatment, the pain symptoms of the patient basically disappear, and the joint mobility is improved;
(3) And (3) invalidation: after 2 courses of external treatment, pain and joint limitation were not improved or even aggravated.
The result of the curative effect evaluation is as follows:
after 60 patients with ankylosing spondylitis are treated by using the external medicine bag for 2 treatment courses, 4 patients are cured, 52 patients are effective, and 4 patients are ineffective. The total effective rate is very remarkable.
Example 3
Typical cases
Case 1
For a certain period, male, age 26, lumbago and back pain for more than 2 years, no clear inducement before 2 years, obvious nighttime pain, soreness and weakness of waist and knees, aggravation after weather change and fatigue, obvious fatigue and hypodynamia, confirmed diagnosis as ankylosing spondylitis after perfect related examination, no obvious pain in waist and back, insomnia and no symptom repeated attack after 2 courses of treatment by using an externally-applied medicine bag.
Case 2
Von, male, 25 years old, repeated pain in the back and waist for 4 years, obvious pain in the back and waist at night, stiffness in the morning and relief after activities. After 2 courses of treatment with the external-use medicine bag, the symptoms of the pain of the waist and the back gradually disappear without relapse.
Case 3
Liu Zhi, female, 28 years old, recovery of pain in the waist and back for 3 years, obvious pain in the waist and back and obvious pain at night. After taking a plurality of medicines, a plurality of treatment modes (acupuncture, massage and the like) are tried, the treatment effect is not obvious, and after 2 treatment courses of external medicine bags, the symptoms of waist and back pain gradually disappear and the disease does not relapse.
The foregoing is merely exemplary and illustrative of the principles of the present invention and various modifications, additions and substitutions of the specific embodiments described herein may be made by those skilled in the art without departing from the principles of the present invention or exceeding the scope of the claims set forth herein.

Claims (5)

1. A traditional Chinese medicine compound composition for treating ankylosing spondylitis is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight:
15-25g of parasitic loranthus, 15-25g of radix achyranthis bidentatae, 5-15g of cassia twig, 5-20g of lycopodium clavatum, 5-15g of safflower, 5-15g of folium artemisiae argyi, 5-20g of garden balsam stem, 10-15g of aconite accessory piece, 5-15g of radix aconiti, 10g of asarum, 5-15g of beautiful sweetgum fruit, 5-15g of borneol, 10-15g of cortex acanthopanacis, 10-15g of wooly datchmanspipe herb, 5-10g of fructus polygoni orientalis and 25-35g of actinolite.
2. The traditional Chinese medicine compound composition of claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight:
20g of parasitic loranthus, 20g of radix achyranthis bidentatae, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of folium artemisiae argyi, 10g of garden balsam stem, 10g of radix aconiti lateralis preparata, 10g of radix aconiti, 10g of asarum, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of wooly datchmanspipe herb, 10g of fructus polygoni orientalis and 30g of actinolite.
3. The external medicine package prepared by the compound traditional Chinese medicine composition of claim 1 or 2, which is characterized in that the external medicine package is obtained by crushing the traditional Chinese medicines, spraying a proper amount of white spirit into the medicine powder, uniformly mixing the medicine powder and putting the medicine powder into a cloth bag.
4. The use of the compound Chinese medicinal composition of claim 1 or 2 in the preparation of a medicament for treating ankylosing spondylitis.
5. Use of the external pharmaceutical pack according to claim 3 for the preparation of a medicament for treating ankylosing spondylitis.
CN202211702614.5A 2022-12-29 2022-12-29 Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag Active CN115804805B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008002953U1 (en) * 2008-03-01 2008-07-03 Reither, Robert, Dr. Chinese herbal recipes for the treatment of musculoskeletal disorders in humans and animals
CN104096022A (en) * 2014-07-29 2014-10-15 张宗云 External use compound Chinese herbal preparation for treating ankylosing spondylitis and preparation method thereof
CN106389720A (en) * 2016-10-25 2017-02-15 李本虎 Medicine for treating ankylosing spondylitis and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008002953U1 (en) * 2008-03-01 2008-07-03 Reither, Robert, Dr. Chinese herbal recipes for the treatment of musculoskeletal disorders in humans and animals
CN104096022A (en) * 2014-07-29 2014-10-15 张宗云 External use compound Chinese herbal preparation for treating ankylosing spondylitis and preparation method thereof
CN106389720A (en) * 2016-10-25 2017-02-15 李本虎 Medicine for treating ankylosing spondylitis and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
庞立波, 王素美, 丁立钧, 金新美: "中药熏蒸治疗强直性脊柱炎临床观察", 山东中医杂志, vol. 22, no. 04, pages 208 *
李晓妮;杨淑彬;: "止痹方蒸气浴治疗强直性脊柱炎43例", 陕西中医, vol. 34, no. 07, pages 847 *

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