CN115804805B - Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag - Google Patents

Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag Download PDF

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CN115804805B
CN115804805B CN202211702614.5A CN202211702614A CN115804805B CN 115804805 B CN115804805 B CN 115804805B CN 202211702614 A CN202211702614 A CN 202211702614A CN 115804805 B CN115804805 B CN 115804805B
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ankylosing spondylitis
traditional chinese
bag
chinese medicine
external
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CN115804805A (en
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黄旦
刘健
汪元
张皖东
曹云祥
万磊
纵瑞凯
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First Affiliated Hospital of AHUTCM
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

A Chinese medicinal compound composition for treating ankylosing spondylitis and an external medicinal bag belong to the technical field of Chinese medicinal compounds for treating ankylosing spondylitis, and consist of 15-25g of Chinese taxillus twig, 15-25g of radix achyranthis bidentatae, 5-15g of cassia twig, 5-20g of lycopodium clavatum, 5-15g of safflower, 5-15g of mugwort leaf, 5-20g of garden balsam stem, 10-15g of aconite, 5-15g of radix aconiti, 10g of asarum, 5-15g of fructus liquidambaris, 5-15g of borneol, 10-15g of cortex acanthopanacis, 10-15g of herba aristolochiae, 5-10g of fructus polygoni orientalis and 25-35g of actinolite. The invention is prepared according to the principle of monarch, minister, assistant and guide, and has the effects of tonifying kidney, strengthening governor meridian, warming channel, dredging collaterals, activating blood and relieving pain. Meanwhile, the external medicine bag can penetrate into the human body through the channels and collaterals on the surface of the human body, so that better treatment effect is exerted.

Description

Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compounds for treating ankylosing spondylitis, and particularly relates to a traditional Chinese medicine compound composition for treating ankylosing spondylitis and an external medicine bag.
Background
Ankylosing spondylitis (ankylosing spondylitis, AS) is a common inflammatory rheumatic disease affecting the central axis bone, causing characteristic inflammatory back pain, which can lead to structural and functional impairment and reduced quality of life. The incidence of AS in chinese population is similar to that of european population, about 0.24%. About 4% of patients lost some of their labor after 5 years of onset of AS, and about 50% of patients lost some of their labor after 45 years of onset. The pathogenesis of AS is not well known and may be related to genetics, infections, environment, immunity, etc. The key to treatment is to relieve the inflammatory symptoms of AS patients AS soon AS possible, relieve pain, control the disease activity, delay the progression of the disease, and reduce the teratogenic and disabling injuries of the patients caused by the disease. However, the existing AS therapeutic drugs include nonsteroidal anti-inflammatory drugs, immunosuppressants, antirheumatic drugs, glucocorticoids and the like for improving the illness state, have large side effects after long-term administration, have intolerance, have adverse reactions such AS affected gastrointestinal liver and kidney functions and the like, and cause heavy physical and psychological burden for patients.
The traditional Chinese medicine can effectively improve clinical symptoms of AS patients and reduce toxic and side effects, thereby further improving the life quality of patients. Chinese patent application CN103893427A discloses a traditional Chinese medicine composition for treating ankylosing spondylitis and a preparation method thereof, and the traditional Chinese medicine composition is prepared from the following raw materials: radix Puerariae, radix Angelicae sinensis, radix Paeoniae alba, radix rehmanniae Preparata, herba Epimedii, colla Cornus Cervi, fructus Lycii, radix Pseudostellariae, notopterygii rhizoma, radix Angelicae Pubescentis, radix Paeoniae Rubra, corni fructus, herba Taxilli, radix Dipsaci, ramulus Cinnamomi, saviae Miltiorrhizae radix, caulis Spatholobi, fructus Lycii, fructus Ligustri Lucidi, cistanchis herba, achyranthis radix, rhizoma Drynariae, rhizoma Cibotii, eucommiae cortex, rhizoma Curculiginis, polygoni Multiflori radix, radix Morindae officinalis, fructus Ligustri Lucidi, radix scrophulariae, radix aucklandiae, rhizoma Ligustici Chuanxiong, poria, radix Gentianae Marcrophyllae, radix Saposhnikoviae, radix Cyathulae, herba asari, ramulus Cinnamomi, radix Clematidis, radix Aconiti Preparata, myrrha, olibanum Preparata, glycyrrhrizae radix and squama Manis. The traditional Chinese medicine composition has the advantages of safe propaganda and clinical application, no irritation to viscera after oral administration, convenience for taking the preparation, guarantee of the purity of the medicine, convenience for storage, remarkable curative effect, multiple absorption of active ingredients, good performance of medicine property, treatment of both principal and secondary aspect of disease, and total effective rate up to 97%.
Chinese patent application CN106619988A discloses a traditional Chinese medicine foot bath powder for treating lumbago and skelalgia and a preparation method thereof, wherein the formula comprises the following components: ramulus Cinnamomi, radix Saposhnikoviae, folium Artemisiae Argyi, herba Schizonepetae, notopterygii rhizoma, radix Angelicae Pubescentis, herba Taxilli, cortex Acanthopancis, carthami flos each 20g, eucommiae cortex, radix Angelicae sinensis, cortex Cinnamomi, radix rehmanniae Preparata, radix Dipsaci, herba Lycopodii, herba Speranskiae Tuberculatae, radix Angelicae Dahuricae, ramulus Mori, lignum sappan, radix Clematidis each 30g, and radix Olibanum, myrrha, radix Cyathulae, and Achyranthis radix each 16g. The preparation is foot bath powder, and has good therapeutic effect on lumbago and skelalgia.
Disclosure of Invention
The invention aims to solve the technical problem of providing a traditional Chinese medicine compound composition and an external medicine bag for treating ankylosing spondylitis, which are prepared according to the principle of monarch, minister, assistant and guide prescription, and are used for tonifying kidney, strengthening governor meridian, warming channel, dredging collaterals, activating blood and relieving pain. Meanwhile, the external medicine bag can penetrate into the human body through the channels and collaterals on the surface of the human body, so that better treatment effect is exerted.
In order to achieve the above purpose, the technical scheme adopted by the invention is as follows:
a Chinese medicinal compound composition for treating ankylosing spondylitis is prepared from the following Chinese medicinal raw materials in part by weight:
15-25g of Chinese taxillus twig, 15-25g of achyranthes root, 5-15g of cassia twig, 5-20g of lycopodium clavatum, 5-15g of safflower, 5-15g of mugwort leaf, 5-20g of garden balsam stem, 10-15g of aconite, 5-15g of common monkshood mother root, 10g of manchurian wildginger, 5-15g of beautiful sweetgum fruit, 5-15g of borneol, 10-15g of cortex acanthopanacis, 10-15g of herba aristolochiae, 5-10g of water safflower seed and 25-35g of actinolite.
The Chinese herbal compound composition of the invention has the following treatment rules: tonify kidney, strengthen governor meridian, warm meridians, activate blood and relieve pain. Because ankylosing spondylitis patients take lumbago and backache as main symptoms, the ankylosing spondylitis patients belong to the category of arthralgia syndrome in traditional Chinese medicine, and are mainly caused by pain caused by obstruction, and the patients have deficiency of spleen and kidney, deficiency of vital qi, easy invasion of exogenous evil, and obstruction of qi and blood circulation, and are caused by stasis, and pain caused by obstruction. Therefore, in the compound composition, the Chinese taxillus herb and the achyranthes root are monarch drugs, and can tonify liver and kidney and dispel wind-damp. Ramulus Cinnamomi, radix Aconiti lateralis Preparata, herba asari, folium Artemisiae Argyi, and radix et rhizoma Rhei Wu Wenjing for dredging collaterals, cortex Acanthopanacis, fructus Lipuidambaris, herba Aristolochiae Mollissimae, herba Speranskiae Tuberculatae, and herba Lycopodii for dispelling pathogenic wind, removing dampness, and relieving arthralgia, and can be used as ministerial drugs. Safflower and fructus polygoni orientalis have the effects of promoting blood circulation, removing blood stasis and relieving pain, actinolite tonifies kidney and dispels cold, and are taken as adjuvant drugs together, borneol Xin Tou has the effects of inducing resuscitation, relieving pain, and white spirit has the effects of promoting blood circulation and dredging channels as guide, and all drugs are led to directly reach the disease site. The external therapeutic principle can be used for curing ankylosing spondylitis by penetrating the channels and collaterals of the body surface of the human body.
As a preferable technical scheme of the traditional Chinese medicine compound composition for treating ankylosing spondylitis, the traditional Chinese medicine compound composition is prepared from the following traditional Chinese medicine raw materials in parts by weight:
20g of mistletoe, 20g of achyranthes root, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of mugwort leaf, 10g of garden balsam stem, 10g of aconite, 10g of manchurian wildginger, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of herba aristolochiae, 10g of fructus polygoni orientalis and 30g of actinolite.
The invention also provides an external medicine bag prepared by using the Chinese herbal medicine compound composition, which is prepared by crushing the Chinese herbal medicines, sprinkling a proper amount of white spirit into the medicinal powder, uniformly mixing the medicinal powder, and placing the medicinal powder into a cloth bag.
The traditional Chinese medicine compound composition can be used for treating ankylosing spondylitis and has a good treatment effect. The external medicine bag can be made into the medicine bag which can penetrate into human body through the channels and collaterals of the surface of the human body, thereby playing a better therapeutic role.
Detailed Description
The present invention is described in further detail below with reference to examples.
Example 1
An external medicine bag for treating ankylosing spondylitis:
the compound composition comprises the following components: 20g of mistletoe, 20g of achyranthes root, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of mugwort leaf, 10g of garden balsam stem, 10g of aconite, 10g of manchurian wildginger, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of herba aristolochiae, 10g of fructus polygoni orientalis and 30g of actinolite.
The preparation method comprises the following steps: pulverizing the above materials, sprinkling 200g of Chinese liquor into the powder, mixing the powder, and placing into cloth bag to obtain topical medicated bag.
Before use, the powder is put into a microwave oven for heating for 3 minutes, and then is put into the waist and back of a patient suffering from ankylosing spondylitis for hot compress.
Example 2
Efficacy statistics
60 cases of ankylosing spondylitis patients (patients in the first affiliated hospital clinic of Anhui university of traditional Chinese medicine) were given the external medicine package treatment prepared according to the method of example 1; of these, 56 men and 4 women, aged 20-28 years, with an average age of 24 years. The course of the disease is 0.5-5 years. Clinical manifestations are efficacy assessment criteria of pain in the waist and back, stiffness, limited activity, etc.:
(1) And (3) curing: after 2 courses of treatment with the topical medicated bag, pain symptoms of patients disappear, and joints can move normally;
(2) And (3) the following steps: after 2 treatment courses of the external medicine bag treatment, the pain symptoms of the patient basically disappear, and the joint mobility is improved;
(3) Invalidation: pain and joint limitation did not improve or even aggravate after 2 courses of topical drug treatment.
Efficacy assessment results:
after 60 patients with ankylosing spondylitis are treated by using the external medicine bag for 2 treatment courses, 4 patients are cured, and the patients are effectively treated by 52 patients and are not treated by 4 patients. The total effective rate is very obvious.
Example 3
Typical cases
Case 1
Duan Mou A, 26 years old, pain in the waist and back is 2 years old, pain in the waist and back is not caused by clear causes before 2 years, pain in the night is obvious, soreness of the waist and knees is accompanied, the weather changes and aggravation after tiredness are carried out, fatigue and debilitation are obvious, ankylosing spondylitis is diagnosed after perfecting the relevant examination, and after 2 treatment courses, the external medicine bag is used for treating, the pain in the waist and back is not obvious, the night is sleep and the symptom is not repeated.
Case 2
Feng Mou it is used for men, 25 years old, and has the effects of relieving pain in waist and back, pain at night, stiffness in morning, and pain after activity. After 2 treatment courses, the symptoms of the lumbago and backache gradually disappear and do not recur.
Case 3
Liu Mou female, 28 years old, had back pain for 3 years, and had back pain and night pain evident. Various medicines are taken once, various treatment modes (acupuncture, massage and the like) are tried, the treatment effect is not obvious, and after 2 treatment courses of treatment by using the external medicine bag, the symptoms of the lumbago and backache gradually disappear and do not relapse.
The foregoing is merely illustrative and explanatory of the principles of the invention, as various modifications and additions may be made to the specific embodiments described, or similar thereto, by those skilled in the art, without departing from the principles of the invention or beyond the scope of the appended claims.

Claims (2)

1. A traditional Chinese medicine external medicine bag for treating ankylosing spondylitis is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 20g of mistletoe, 20g of achyranthes root, 10g of cassia twig, 10g of lycopodium clavatum, 10g of safflower, 10g of mugwort leaf, 10g of garden balsam stem, 10g of accessory piece, 10g of common monkshood mother root, 10g of asarum herb, 10g of beautiful sweetgum fruit, 10g of borneol, 10g of cortex acanthopanacis, 10g of herba aristolochiae, 10g of fructus polygoni orientalis and 30g of actinolite;
the preparation method of the traditional Chinese medicine external-use medicine bag comprises the following steps: pulverizing the above materials, sprinkling appropriate amount of Chinese liquor into the medicinal powder, mixing the medicinal powder, and placing into cloth bag to obtain topical medicinal bag.
2. The use of the external pack according to claim 1 for the preparation of a medicament for the treatment of ankylosing spondylitis.
CN202211702614.5A 2022-12-29 2022-12-29 Traditional Chinese medicine compound composition for treating ankylosing spondylitis and external medicine bag Active CN115804805B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008002953U1 (en) * 2008-03-01 2008-07-03 Reither, Robert, Dr. Chinese herbal recipes for the treatment of musculoskeletal disorders in humans and animals
CN104096022A (en) * 2014-07-29 2014-10-15 张宗云 External use compound Chinese herbal preparation for treating ankylosing spondylitis and preparation method thereof
CN106389720A (en) * 2016-10-25 2017-02-15 李本虎 Medicine for treating ankylosing spondylitis and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE202008002953U1 (en) * 2008-03-01 2008-07-03 Reither, Robert, Dr. Chinese herbal recipes for the treatment of musculoskeletal disorders in humans and animals
CN104096022A (en) * 2014-07-29 2014-10-15 张宗云 External use compound Chinese herbal preparation for treating ankylosing spondylitis and preparation method thereof
CN106389720A (en) * 2016-10-25 2017-02-15 李本虎 Medicine for treating ankylosing spondylitis and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
中药熏蒸治疗强直性脊柱炎临床观察;庞立波, 王素美, 丁立钧, 金新美;山东中医杂志;22(04);第208页左栏第1段,右栏第3段以及第209页 讨论部分 *
止痹方蒸气浴治疗强直性脊柱炎43例;李晓妮;杨淑彬;;陕西中医;34(07);第847页 *

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