CN110721219A - Traditional Chinese medicine for treating allergic rhinitis - Google Patents

Traditional Chinese medicine for treating allergic rhinitis Download PDF

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Publication number
CN110721219A
CN110721219A CN201911242578.7A CN201911242578A CN110721219A CN 110721219 A CN110721219 A CN 110721219A CN 201911242578 A CN201911242578 A CN 201911242578A CN 110721219 A CN110721219 A CN 110721219A
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chinese medicine
traditional chinese
radix
allergic rhinitis
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吴曙辉
姜婷婷
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Shanghai Baoshan Integrated Traditional Chinese And Western Medicine Hospital Baoshan Branch Of Shuguang Hospital Affiliated To Shanghai University Of Traditional Chinese Medicine
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Shanghai Baoshan Integrated Traditional Chinese And Western Medicine Hospital Baoshan Branch Of Shuguang Hospital Affiliated To Shanghai University Of Traditional Chinese Medicine
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Priority to CN201911242578.7A priority Critical patent/CN110721219A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents

Abstract

The invention discloses a traditional Chinese medicine for treating allergic rhinitis, which mainly solves the problems that the medicine treatment in the prior art has epistaxis and the side effects of long-term hormone administration, and is easy to relapse. The traditional Chinese medicine comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of magnolia flower, 15-25 parts of astragalus, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 1-10 parts of baical skullcap root, 1-8 parts of ephedra, 1-8 parts of asarum, 1-12 parts of liquorice, 1-11 parts of cicada slough, 1-11 parts of salvia miltiorrhiza, 1-8 parts of cinnamon, 1-11 parts of madder, 5-15 parts of earthworm and 5-15 parts of cocklebur fruit. Through the scheme, the invention achieves the purposes of obviously reducing the recurrence rate and having small side effect.

Description

Traditional Chinese medicine for treating allergic rhinitis
Technical Field
The invention relates to the technical field of medicines, in particular to a traditional Chinese medicine for treating allergic rhinitis.
Background
Allergic Rhinitis (AR) is also known as allergic rhinitis, and nearly 40% of patients with AR can have bronchial asthma accompanied by pulmonary symptoms such as wheezing, cough, dyspnea, chest distress, etc.; at present, global AR patients account for 20% -30% of the total population, the morbidity of China is also in a remarkable rising trend in recent years, the AR has attracted extreme attention of scholars at home and abroad, and the AR is a public health and social medicine problem to be solved urgently. According to 2015 latest clinical guidelines of allergic rhinitis, intranasal glucocorticoids and second-generation oral antihistamines are recommended medicaments for AR treatment at present, the AR is treated by nasal glucocorticoids for a long time, the incidence rate of epistaxis can reach 20%, nasal symptoms are easy to relapse after drug withdrawal, and the drug compliance is obviously reduced due to the fear of certain side effects of the nasal hormones of patients for a long time.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine for treating allergic rhinitis, and aims to solve the problems that epistaxis and side effects of long-term hormone administration exist in the existing medicine treatment, and relapse is easy.
In order to solve the above problems, the present invention provides the following technical solutions:
the traditional Chinese medicine for treating allergic rhinitis comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of magnolia flower, 15-25 parts of astragalus root, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 1-10 parts of baical skullcap root, 1-8 parts of moxibustion ephedra, 1-8 parts of asarum and 1-12 parts of liquorice.
Specifically, the traditional Chinese medicine for treating allergic rhinitis also comprises the following components in parts by weight: 1-11 parts of cicada slough, 1-11 parts of salvia miltiorrhiza, 1-8 parts of cinnamon, 1-11 parts of madder, 5-15 parts of earthworm and 5-15 parts of cocklebur fruit.
Specifically, 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus, 5 parts of bighead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of moxibustion ephedra herb, 1 part of asarum and 1 part of liquorice.
Specifically, 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus, 5 parts of bighead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of ephedra, 1 part of asarum, 1 part of liquorice, 1 part of cicada slough, 1 part of salvia miltiorrhiza, 1 part of cinnamon, 1 part of madder, 5 parts of earthworm and 5 parts of cocklebur fruit.
Specifically, 15 parts of angelica dahurica, 15 parts of biond magnolia flower, 25 parts of astragalus, 15 parts of bighead atractylodes rhizome, 15 parts of divaricate saposhnikovia root, 10 parts of baical skullcap root, 8 parts of ephedra, 8 parts of asarum, 12 parts of liquorice, 11 parts of cicada slough, 11 parts of salvia miltiorrhiza, 8 parts of cinnamon, 11 parts of madder, 15 parts of earthworm and 15 parts of cocklebur fruit.
Specifically, 10 parts of angelica dahurica, 10 parts of biond magnolia flower, 20 parts of astragalus, 10 parts of bighead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 5 parts of baical skullcap root, 3 parts of ephedra, 3 parts of asarum, 6 parts of liquorice, 6 parts of cicada slough, 6 parts of salvia miltiorrhiza, 3 parts of cinnamon, 6 parts of madder, 10 parts of earthworm and 10 parts of cocklebur fruit.
Specifically, the traditional Chinese medicine is granules or mixture.
Compared with the prior art, the invention has the following beneficial effects: the traditional Chinese medicine formula has the effects of tonifying qi of spleen and lung, benefiting wei-defense, consolidating superficial resistance, expelling wind and removing cold and dredging orifices; the prescription is clinically applied to patients with allergic rhinitis, can effectively improve the far and near clinical curative effect, remarkably reduce the recurrence rate, has small side effect and less adverse reaction, and can effectively improve the symptoms of the patients and improve the life quality of the patients. In addition, the recipe can improve the indexes of patients such as inflammatory factors, IgE levels and the like.
Detailed Description
The present invention is further illustrated by the following examples, which include, but are not limited to, the following examples.
The traditional Chinese medicine for treating allergic rhinitis comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of magnolia flower, 15-25 parts of astragalus, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 1-10 parts of baical skullcap root, 1-8 parts of ephedra, 1-8 parts of asarum, 1-12 parts of liquorice, 1-11 parts of cicada slough, 1-11 parts of salvia miltiorrhiza, 1-8 parts of cinnamon, 1-11 parts of madder, 5-15 parts of earthworm and 5-15 parts of cocklebur fruit.
The pharmacological actions of the above-mentioned various important raw materials are respectively as follows:
radix angelicae: warm in nature, pungent in flavor, fragrant in smell and slightly bitter; dispel wind-damp, activate blood and discharge pus, promote granulation and alleviate pain. Can be used for treating headache, toothache, nasosinusitis, hemorrhoid, leucorrhea with red and white discharge, carbuncle, cellulitis, pyocutaneous disease, and skin pruritus.
And (3) magnolia flower: pungent and warm; dispel wind-cold, unblock nasal orifices. Can be used for treating headache due to wind-cold evil, nasal obstruction, nasosinusitis, and thick nasal discharge.
Astragalus root: bitter and cold. It enters lung, heart, liver, gallbladder and large intestine meridians. The functions are mainly as follows: clearing heat and purging fire, eliminating dampness and removing toxicity, stopping bleeding, and preventing miscarriage; can be used for treating cough due to lung heat, fever, dizziness, headache due to liver fire, conjunctival congestion, swelling and pain, jaundice due to damp-heat pathogen, dysentery, heat stranguria, hematemesis, metrorrhagia, metrostaxis, threatened abortion, swelling, and furuncle.
White atractylodes rhizome: bitter and sweet taste, warm nature; invigorate spleen, replenish qi, dry dampness, induce diuresis, stop sweating, prevent abortion. Can be used for treating spleen deficiency, anorexia, abdominal distention, diarrhea, phlegm retention, dizziness, palpitation, edema, spontaneous perspiration, and threatened abortion.
Wind prevention: pungent and sweet in flavor and warm in nature; has effects in relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness, and can be used for treating wind-cold type common cold, headache, fever, joint pain, and tetanus; in addition, Ledebouriella root flower, also can be used for medicine.
Scutellaria baicalensis: has effects of clearing heat and eliminating dampness. For fever due to damp-heat, it can be used in combination with pulvis Talci, fructus Amomi rotundus, and Poria; for dysentery and abdominal pain due to damp-heat, it is combined with Bai Shao, Ge Gen and gan Cao; for jaundice due to accumulation of damp-heat, it is combined with Yin Chen, Zhi Zi and Lophatherum gracile.
And (3) moxibustion of ephedra: has the effects of inducing sweat, dispelling cold, dispersing lung qi, relieving asthma, inducing diuresis, and relieving swelling, and also has the effects of warming spleen and stomach and invigorating spleen.
Asarum: warm in nature and with little toxicity; has effects in expelling pathogenic wind, expelling cold, warming lung, promoting diuresis, and inducing resuscitation. It is used to treat headache due to wind-cold evil, nasosinusitis, toothache, phlegm and fluid retention, cough, and rheumatalgia.
Cicada slough: sweet and cold in nature. Entering lung and liver meridians; dispel wind and remove heat, relieve sore throat, promote eruption, remove nebula and relieve spasm. Can be used for treating wind-heat type common cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion, nebula, convulsion, and tetanus.
Red sage root: bitter and slightly cold; has the functions of promoting blood circulation to disperse blood clots, cooling blood and tranquilizing. Can be used for treating menoxenia, dysmenorrhea, amenorrhea, pain of heart and abdomen, pyretic arthralgia, swelling and pain, vexation, and insomnia. Modern medical research shows that: the Saviae Miltiorrhizae radix contains tanshinone, protocatechuic aldehyde, protocatechuic acid, tanshinol, vitamin E, etc., and has effects of tonifying heart, strengthening myocardial contraction force, and improving heart function, without increasing myocardial consumption; the traditional Chinese medicine salvia miltiorrhiza has the effects of promoting blood circulation and removing blood stasis, and has the effects of promoting blood circulation and removing blood stasis, expanding blood vessels, improving the capability of tissues to resist anoxia and the like. Modern medicine considers that blood stasis is mainly microcirculation disturbance and blood rheology change, so that dizziness caused by ischemia and hypoxia are caused.
Cinnamon: pungent and sweet in flavor, warm in nature and entering spleen, kidney, heart and liver meridians. Has the functions of supplementing fire, supporting yang, dispelling cold, relieving pain, warming and dredging channels and collaterals, and guiding fire to origin. Can be used for treating soreness of waist and knees, aversion to cold, cold limbs, sexual impotence, frequent micturition, abdominal pain, diarrhea, asthma, and sweating of head due to cold limbs caused by kidney yang deficiency and spleen and kidney yang deficiency.
Madder root: cooling blood and promoting blood circulation, removing blood stasis and restoring menstrual flow; can be used for treating hematemesis, epistaxis, metrorrhagia, traumatic hemorrhage, amenorrhea, blood stasis, arthralgia, and traumatic injury with swelling and pain.
Earthworm: salty and cold. It enters liver, lung and kidney meridians. The functions are mainly as follows: stop spasm, extinguish wind, unblock collaterals and relieve dyspnea. It can be used for treating fever, mania, convulsion, liver yang headache, conjunctival congestion, swelling and pain, apoplexy, hemiplegia, rheumatalgia, lung heat cough and asthma, laryngopharynx swelling, and dysuria. Modern medicine proves that the traditional Chinese medicine also has the effects of dredging collaterals, promoting blood circulation by removing blood stasis and resisting thrombus.
Fructus xanthil: can be used for the adjuvant treatment of common cold, especially nasal obstruction and thick nasal discharge. In addition, the cocklebur fruit can also dissipate dampness and relieve pain, can perform auxiliary regulation and treatment on arthralgia, can promote qi and blood circulation and dredge channels, and can perform symptomatic treatment on arthritis caused by diseases such as rheumatism, rheumatoid and the like.
Example 1
The traditional Chinese medicine for treating allergic rhinitis comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus root, 5 parts of largehead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of moxibustion ephedra herb, 1 part of asarum and 1 part of liquorice.
Example 2
The traditional Chinese medicine for treating allergic rhinitis comprises the following components in parts by weight: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus root, 5 parts of largehead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of moxibustion ephedra herb, 1 part of manchurian wildginger, 1 part of liquoric root, 1 part of cicada slough, 1 part of danshen root, 1 part of cassia bark, 1 part of India madder root, 5 parts of earthworm and 5 parts.
Example 3
The traditional Chinese medicine for treating allergic rhinitis also comprises the following components in parts by weight: 15 parts of angelica dahurica, 15 parts of biond magnolia flower, 25 parts of astragalus root, 15 parts of largehead atractylodes rhizome, 15 parts of divaricate saposhnikovia root, 10 parts of baical skullcap root, 8 parts of moxibustion ephedra herb, 8 parts of manchurian wildginger, 12 parts of liquoric root, 11 parts of cicada slough, 11 parts of salvia miltiorrhiza, 8 parts of cassia bark, 11 parts of madder, 15 parts of earthworm and 15 parts of cocklebur fruit.
Example 4
The traditional Chinese medicine for treating allergic rhinitis also comprises the following components in parts by weight: 10 parts of angelica dahurica, 10 parts of biond magnolia flower, 20 parts of astragalus root, 10 parts of largehead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 5 parts of baical skullcap root, 3 parts of moxibustion ephedra herb, 3 parts of manchurian wildginger, 6 parts of liquoric root, 6 parts of cicada slough, 6 parts of salvia miltiorrhiza, 3 parts of cassia bark, 6 parts of India madder root, 10 parts of earthworm and 10 parts of cock.
Examples of clinical observations:
1. the patient is old and female, 23 years old, has repeated nasal itching and sneezing, is accompanied with nasal obstruction and thin nasal discharge, and has pale complexion, aversion to wind and cold, listlessness and hypodynamia, pale tongue, thin and white tongue fur and thready and weak pulse. The identification is as follows: lung qi is deficient cold. Therapeutic method: invigorating spleen, tonifying lung, dredging orifice, and dispelling pathogenic wind. Prescription: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus root, 5 parts of largehead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of moxibustion ephedra herb, 1 part of asarum and 1 part of liquorice. 1 dose daily, decocting with 600ml water to 200ml, respectively 100ml in the morning and evening, and treating for 6 weeks. The rechecking is obviously improved, and the nasal itching and the sneezing are only performed once after the follow-up for 3 months, but the obvious degree is reduced.
2. The patient is high, male, 48 years old, has nasal obstruction and nasal discharge in nearly 2 weeks, and is accompanied by headache, dyspnea, dry cough, aversion to wind and cold. There is a history of allergic rhinitis and chronic sinusitis. Patients have vexation, dreaminess, pale tongue, white and greasy tongue coating, and thready pulse. The identification is as follows: insecurity of the defensive exterior. Therapeutic method: tonify lung, warm kidney, dispel wind and dredge orifices. Prescription: 5 parts of angelica dahurica, 5 parts of biond magnolia flower, 15 parts of astragalus root, 5 parts of largehead atractylodes rhizome, 5 parts of divaricate saposhnikovia root, 1 part of baical skullcap root, 1 part of moxibustion ephedra herb, 1 part of manchurian wildginger, 1 part of liquoric root, 1 part of cicada slough, 1 part of danshen root, 1 part of cassia bark, 1 part of India madder root, 5 parts of earthworm and 5 parts. 1 dose daily, decocting with 600ml water to 200ml, respectively 100ml in the morning and evening, and treating for 4 weeks; antihistamine, hormone and other Chinese medicinal preparations are not used during taking Chinese medicinal preparation. After 3 months of follow-up, the patient has no discomfort such as nasal obstruction, headache and the like.
3. The patient is Zhangzhi, male, age 35, repeatedly sneezing, rhinocnesmus, nasal obstruction, running clear nasal discharge all year round, night hyperhidrosis, aversion to wind and cold, fatigue and hypodynamia, vexation and shortness of breath, pale tongue, thin and white tongue fur, and wiry and rapid pulse. The identification is as follows: 15 parts of angelica dahurica, 15 parts of biond magnolia flower, 25 parts of astragalus root, 15 parts of largehead atractylodes rhizome, 15 parts of divaricate saposhnikovia root, 10 parts of baical skullcap root, 8 parts of moxibustion ephedra herb, 8 parts of manchurian wildginger, 12 parts of liquoric root, 11 parts of cicada slough, 11 parts of salvia miltiorrhiza, 8 parts of cassia bark, 11 parts of madder, 15 parts of earthworm and 15 parts of cocklebur fruit. Decocting 300ml of water into 100ml, and taking one dose every day for 8 weeks. Half a year of follow-up visit, no obvious outbreak of rhinocnesmus, running nose and the like.
4. The patient is thank for some men, age 33, and has repeated sneezing, nasal itching, nasal obstruction, clear nasal discharge, night sweating, aversion to wind and cold, and wiry and rapid pulse all the year round. The identification is as follows: lung qi is weak. Therapeutic method: to replenish qi, strengthen the exterior, warm the kidney and dredge the orifice. Prescription: 10 parts of angelica dahurica, 10 parts of biond magnolia flower, 20 parts of astragalus root, 10 parts of largehead atractylodes rhizome, 10 parts of divaricate saposhnikovia root, 5 parts of baical skullcap root, 3 parts of moxibustion ephedra herb, 3 parts of manchurian wildginger, 6 parts of liquoric root, 6 parts of cicada slough, 6 parts of salvia miltiorrhiza, 3 parts of cassia bark, 6 parts of India madder root, 10 parts of earthworm and 10 parts of cock. Decocting 300ml of water into 100ml, and taking one dose every day for 8 weeks. After 3 months of follow-up, no obvious outbreak of rhinocnesmus, running nose and the like exists.
The experimental group: the traditional Chinese medicine composition is used for clinically treating 30 patients with allergic rhinitis, the curative effect standard refers to the traditional Chinese medicine disease diagnosis curative effect standard and the diagnosis principle and the recommended scheme of the allergic rhinitis of the department of otorhinolaryngology of the Chinese medical society in 2004 (Lanzhou), wherein 5 patients are cured, 10 patients are obviously effective, 13 patients are effective, 2 patients are ineffective, and the total effective rate is 93.3%.
Control group: 30 patients take loratadine tablets according to 5 mg/time 1 time per day before sleep; 1 week is taken as 1 course of treatment, 4 courses of treatment are taken continuously, wherein 4 cases are cured, 8 cases are effective, 10 cases are effective, 8 cases are ineffective, and the total effective rate is 73.3%.
The experimental group is obviously superior to the loratadine treatment group; the Chinese medicine symptoms of the compound group are effectively reduced compared with those before treatment, and are superior to a control group (P is less than 0.05), the treatment effect is superior to that of a western medicine treatment group regardless of the short-term or long-term treatment effect, and indexes such as inflammatory factors, IgE levels and the like of patients can be improved; the clinical curative effect of the traditional Chinese medicine prescription on allergic rhinitis is better than that of a loratadine treatment group, and the recurrence rate of the compound group is lower than that of the loratadine group after the medicine is stopped for 3 months, which shows that the curative effect of the traditional Chinese medicine is more stable and lasting than that of western medicines.
In the aspect of treating AR, the traditional Chinese medicine focuses on treating both principal and secondary aspects of diseases and conditioning the whole body, and the traditional Chinese medicine can not only improve the serum immunoglobulin level of a human body, but also enhance the phagocytosis and sterilization capacity of macrophages, thereby achieving the effect of radically treating the diseases. Especially has unique advantages in the aspect of long-term curative effect.
AR refers to chronic inflammatory diseases of the nasal mucosa mediated by specific immunoglobulin E (IgE) after allergen exposure; with the rise of the incidence of diseases year by year, huge economic burden is brought to families and society of patients, and the daily life, emotional state, mental health and the like of people are influenced. And AR belongs to the categories of allergic rhinitis, allergic sneezing and allergic water in the traditional Chinese medicine. The disease location is mainly in the lung, spleen and kidney, the etiology is mostly exogenous wind-cold and invasion of foreign qi, the nature is deficient and the index is excessive, and the treatment is mainly to tonify qi, strengthen exterior, dispel wind and dredge orifices. In the national major meeting of allergic rhinitis, Zhanguo professor also puts forward the importance of traditional Chinese medicine in treating AR, Meta analysis is carried out on a database of the traditional Chinese medicine for effectively treating the allergic rhinitis, and the long-term curative effect of the traditional Chinese medicine on the AR is found to be far better than that of western medicine treatment.
The traditional Chinese medicine formula has the effects of tonifying qi of spleen and lung, benefiting wei and defensive qi, consolidating superficial resistance, expelling wind and removing cold and dredging orifices. The prescription is clinically applied to patients with allergic rhinitis, can effectively improve the far and near clinical curative effect, remarkably reduce the recurrence rate, has small side effect and less adverse reaction, and can effectively improve the symptoms of the patients and improve the life quality of the patients.
The invention is well implemented in accordance with the above-described embodiments. It should be noted that, based on the above structural design, in order to solve the same technical problems, even if some insubstantial modifications or colorings are made on the present invention, the adopted technical solution is still the same as the present invention, and therefore, the technical solution should be within the protection scope of the present invention.
The invention discloses a traditional Chinese medicine for treating allergic rhinitis, which mainly solves the problems that the medicine treatment in the prior art has epistaxis and the side effects of long-term hormone administration, and is easy to relapse. The traditional Chinese medicine comprises the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of magnolia flower, 15-25 parts of astragalus, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 1-10 parts of baical skullcap root, 1-8 parts of ephedra, 1-8 parts of asarum, 1-12 parts of liquorice, 1-11 parts of cicada slough, 1-11 parts of salvia miltiorrhiza, 1-8 parts of cinnamon, 1-11 parts of madder, 5-15 parts of earthworm and 5-15 parts of cocklebur fruit. Through the scheme, the invention achieves the purposes of obviously reducing the recurrence rate and having small side effect.

Claims (7)

1. The traditional Chinese medicine for treating allergic rhinitis is characterized by comprising the following components in parts by weight: 5-15 parts of angelica dahurica, 5-15 parts of magnolia flower, 15-25 parts of astragalus root, 5-15 parts of bighead atractylodes rhizome, 5-15 parts of divaricate saposhnikovia root, 1-10 parts of baical skullcap root, 1-8 parts of moxibustion ephedra, 1-8 parts of asarum and 1-12 parts of liquorice.
2. The traditional Chinese medicine for treating allergic rhinitis according to claim 1, which is characterized by further comprising the following components in parts by weight: 1-11 parts of cicada slough, 1-11 parts of salvia miltiorrhiza, 1-8 parts of cinnamon, 1-11 parts of madder, 5-15 parts of earthworm and 5-15 parts of cocklebur fruit.
3. The traditional Chinese medicine for treating allergic rhinitis according to claim 1, wherein the traditional Chinese medicine is prepared from 5 parts of radix angelicae, 5 parts of flos magnoliae, 15 parts of radix astragali, 5 parts of rhizoma atractylodis macrocephalae, 5 parts of radix saposhnikoviae, 1 part of radix scutellariae, 1 part of ephedra, 1 part of asarum and 1 part of liquorice.
4. The traditional Chinese medicine for treating allergic rhinitis according to claim 2, wherein the traditional Chinese medicine is prepared from 5 parts of radix angelicae, 5 parts of flos magnoliae, 15 parts of radix astragali, 5 parts of rhizoma atractylodis macrocephalae, 5 parts of radix saposhnikoviae, 1 part of radix scutellariae, 1 part of ephedra, 1 part of asarum, 1 part of liquorice, 1 part of periostracum cicada, 1 part of radix salviae miltiorrhizae, 1 part of cortex cinnamomi, 1 part of radix rubiae, 5 parts of lumbricus and 5 parts of fructus xanth.
5. The traditional Chinese medicine for treating allergic rhinitis according to claim 2, which is characterized by comprising 15 parts of radix angelicae, 15 parts of flos magnoliae, 25 parts of radix astragali, 15 parts of rhizoma atractylodis macrocephalae, 15 parts of radix saposhnikoviae, 10 parts of radix scutellariae, 8 parts of ephedra, 8 parts of asarum, 12 parts of liquorice, 11 parts of periostracum cicada, 11 parts of radix salviae miltiorrhizae, 8 parts of cortex cinnamomi, 11 parts of radix rubiae, 15 parts of lumbricus and 15 parts of fructus xanthii.
6. The traditional Chinese medicine for treating allergic rhinitis according to claim 2, wherein the traditional Chinese medicine comprises 10 parts of radix angelicae, 10 parts of flos magnoliae, 20 parts of radix astragali, 10 parts of rhizoma atractylodis macrocephalae, 10 parts of radix saposhnikoviae, 5 parts of radix scutellariae, 3 parts of ephedra, 3 parts of asarum, 6 parts of liquorice, 6 parts of periostracum cicada, 6 parts of radix salviae miltiorrhizae, 3 parts of cortex cinnamomi, 6 parts of radix rubiae, 10 parts of lumbricus and 10 parts of fructus xanthii.
7. The traditional Chinese medicine for treating allergic rhinitis according to any one of claims 1 to 6, wherein the traditional Chinese medicine is granules or mixture.
CN201911242578.7A 2019-12-06 2019-12-06 Traditional Chinese medicine for treating allergic rhinitis Pending CN110721219A (en)

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CN111714542A (en) * 2020-07-30 2020-09-29 上海中医药大学 Formula and application of moxibustion strip or moxibustion column for treating allergic rhinitis
CN113384638A (en) * 2021-07-09 2021-09-14 上海交通大学医学院附属上海儿童医学中心 Traditional Chinese medicine composition for allergic rhinitis, patch and preparation method of patch
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