CN115698713A - 改性hdl的定量方法以及用于该定量方法的分析用试剂 - Google Patents

改性hdl的定量方法以及用于该定量方法的分析用试剂 Download PDF

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Publication number
CN115698713A
CN115698713A CN202180037523.1A CN202180037523A CN115698713A CN 115698713 A CN115698713 A CN 115698713A CN 202180037523 A CN202180037523 A CN 202180037523A CN 115698713 A CN115698713 A CN 115698713A
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modified hdl
hdl
protein
modified
factor
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Chinese (zh)
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泽村达也
垣野明美
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Sawamura Tatsuya
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Shinshu University NUC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7456—Factor V
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00—Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04—Sandwich assay format
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CN202180037523.1A 2020-03-30 2021-03-29 改性hdl的定量方法以及用于该定量方法的分析用试剂 Pending CN115698713A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020059965 2020-03-30
JP2020-059965 2020-03-30
PCT/JP2021/013229 WO2021200797A1 (ja) 2020-03-30 2021-03-29 変性ｈｄｌの定量方法、及びそれに用いる分析用試薬

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CN115698713A true CN115698713A (zh) 2023-02-03

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CN202180037523.1A Pending CN115698713A (zh) 2020-03-30 2021-03-29 改性hdl的定量方法以及用于该定量方法的分析用试剂

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US (1) US20230288437A1 (https=)
EP (1) EP4130030A4 (https=)
JP (1) JP7628320B2 (https=)
CN (1) CN115698713A (https=)
WO (1) WO2021200797A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003279571A (ja) * 2002-03-20 2003-10-02 Kyowa Hakko Kogyo Co Ltd 炎症性疾患検出方法、検出薬、およびその予防治療薬探索方法
CN1543476A (zh) * 2001-08-17 2004-11-03 ��˹��ŵ�� 用于将蛋白定向到胞外体的方法和化合物
CN109580960A (zh) * 2019-01-14 2019-04-05 周明 细胞外囊泡的分离方法、以及检测细胞外囊泡表面标志物的方法和试剂盒
WO2019159934A1 (ja) * 2018-02-14 2019-08-22 国立大学法人信州大学 融合タンパク質、及びそれを用いた高密度リポタンパク質の測定キット

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2200980C (en) 1994-11-30 2009-09-22 Tatsuya Sawamura Mammalian receptors for modified low-density lipoprotein
JP3436444B2 (ja) * 1995-07-21 2003-08-11 ヤマサ醤油株式会社 酸化ｈｄｌの測定法及びキット
WO2003006989A1 (fr) * 2001-07-12 2003-01-23 Kyowa Medex Co., Ltd. Procede de quantification de lipoproteines denaturees, reactifs pour la quantification de lipoproteines denaturees, procede de detection de maladies du systeme circulatoire et reactifs pour la detection de maladies du systeme circulatoire
JP4671823B2 (ja) * 2004-09-27 2011-04-20 シスメックス株式会社 血液凝固因子の不活化方法及び血液凝固因子不活化試料
FI20075245A0 (fi) * 2007-04-11 2007-04-11 Markku Ahotupa Menetelmä oksidatiivisen metabolian arvioimiseksi
JP5706669B2 (ja) 2010-11-10 2015-04-22 独立行政法人国立循環器病研究センター 融合タンパク質、核酸、ベクター、細胞、ｌａｂの測定方法、並びに、ｌａｂ測定用キット
JP6231307B2 (ja) 2013-06-27 2017-11-15 中野 恵正 機能不全ｈｄｌの測定方法、機能不全ｈｄｌ測定用キット、並びに、生活習慣病マーカーの測定方法
JP6362209B2 (ja) * 2013-12-27 2018-07-25 国立研究開発法人国立循環器病研究センター 抗血液凝固剤
JP6096360B1 (ja) 2016-08-12 2017-03-15 旭サナック株式会社 ワーク姿勢変更装置および多工程圧造機
JP7084590B2 (ja) * 2016-10-31 2022-06-15 国立大学法人大阪大学 脂質異常症治療が必要な被検者の選別方法及び選別用試薬

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1543476A (zh) * 2001-08-17 2004-11-03 ��˹��ŵ�� 用于将蛋白定向到胞外体的方法和化合物
JP2003279571A (ja) * 2002-03-20 2003-10-02 Kyowa Hakko Kogyo Co Ltd 炎症性疾患検出方法、検出薬、およびその予防治療薬探索方法
WO2019159934A1 (ja) * 2018-02-14 2019-08-22 国立大学法人信州大学 融合タンパク質、及びそれを用いた高密度リポタンパク質の測定キット
CN109580960A (zh) * 2019-01-14 2019-04-05 周明 细胞外囊泡的分离方法、以及检测细胞外囊泡表面标志物的方法和试剂盒

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
AKEMI KAKINO ET AL.: "Developmental Endothelial Locus-1 (Del-1) Inhibits Oxidized Low-Density Lipoprotein Activity by Direct Binding, and Its Overexpression Attenuates Atherogenesis in Mice", 《CIRCULATION JOURNAL》, 31 December 2016 (2016-12-31), pages 2541 - 2549 *

Also Published As

Publication number Publication date
EP4130030A4 (en) 2024-03-27
EP4130030A1 (en) 2023-02-08
JP7628320B2 (ja) 2025-02-10
WO2021200797A1 (ja) 2021-10-07
US20230288437A1 (en) 2023-09-14
JPWO2021200797A1 (https=) 2021-10-07

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Effective date of registration: 20230817

Address after: No.1, No.1, No.1, xusandingmu, Matsumoto, Nagano, Japan

Applicant after: Sawamura Tatsuya

Address before: No.1, No.1, No.1, xusandingmu, Matsumoto, Nagano, Japan

Applicant before: SHINSHU University