CN115595314B - 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 - Google Patents

表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 Download PDF

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CN115595314B
CN115595314B CN202210214588.5A CN202210214588A CN115595314B CN 115595314 B CN115595314 B CN 115595314B CN 202210214588 A CN202210214588 A CN 202210214588A CN 115595314 B CN115595314 B CN 115595314B
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CN115595314A (zh
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刘树文
温廷益
孙佳慧
李忠财
张芸
邓爱华
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Institute of Microbiology of CAS
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Priority to EP23765754.9A priority patent/EP4458960A1/en
Priority to US18/841,611 priority patent/US20260002182A1/en
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    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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CN202210214588.5A 2022-03-07 2022-03-07 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 Active CN115595314B (zh)

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Application Number Priority Date Filing Date Title
CN202210214588.5A CN115595314B (zh) 2022-03-07 2022-03-07 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法
EP23765754.9A EP4458960A1 (en) 2022-03-07 2023-02-17 Engineering bacterium for expressing aspartate dehydrogenase and method for producing vitamin b5 by fermentation
US18/841,611 US20260002182A1 (en) 2022-03-07 2023-02-17 Engineering bacteria expressing aspartate dehydrogenase and method for producing vitamin b5 by fermentation
JP2024553524A JP2025516089A (ja) 2022-03-07 2023-02-17 アスパラギン酸デヒドロゲナーゼを発現する遺伝子組換え細菌、及び発酵によってビタミンｂ５を生産するための方法
PCT/CN2023/076669 WO2023169176A1 (zh) 2022-03-07 2023-02-17 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法

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CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN115595314B (zh) * 2022-03-07 2025-06-24 中国科学院微生物研究所 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法
CN116024278B (zh) * 2022-12-16 2024-05-07 黑龙江新和成生物科技有限公司 一种发酵法制备d-泛酸的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108728470A (zh) * 2017-04-14 2018-11-02 中国科学院微生物研究所 产β-丙氨酸的重组菌及其构建方法与应用
CN109306343A (zh) * 2017-07-26 2019-02-05 中国科学院微生物研究所 新型天冬氨酸脱氢酶及在天冬氨酸族氨基酸生产上的应用

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KR100421088B1 (ko) * 1995-09-13 2004-06-04 바스프 악티엔게젤샤프트 디-판토산및디-판토텐산또는그의염의생성방법
DE19855314A1 (de) * 1998-12-01 2000-06-08 Degussa Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae
EP2163629B1 (en) * 1999-09-21 2017-03-08 Basf Se Methods and microorganisms for production of panto-compounds
CA2491145A1 (en) * 2002-07-03 2004-01-15 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
JP2004254544A (ja) * 2003-02-25 2004-09-16 Ajinomoto Co Inc 新規リジンデカルボキシラーゼ遺伝子及びｌ−リジンの製造法
CN112625985B (zh) * 2020-12-04 2022-05-31 浙江工业大学 一种高产β-丙氨酸的基因工程菌及共培养制备D-泛酸
CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN115595314B (zh) * 2022-03-07 2025-06-24 中国科学院微生物研究所 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108728470A (zh) * 2017-04-14 2018-11-02 中国科学院微生物研究所 产β-丙氨酸的重组菌及其构建方法与应用
CN109306343A (zh) * 2017-07-26 2019-02-05 中国科学院微生物研究所 新型天冬氨酸脱氢酶及在天冬氨酸族氨基酸生产上的应用

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EP4458960A1 (en) 2024-11-06
CN115595314A (zh) 2023-01-13
JP2025516089A (ja) 2025-05-27
US20260002182A1 (en) 2026-01-01

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