JP2025516089A - アスパラギン酸デヒドロゲナーゼを発現する遺伝子組換え細菌、及び発酵によってビタミンb5を生産するための方法 - Google Patents
アスパラギン酸デヒドロゲナーゼを発現する遺伝子組換え細菌、及び発酵によってビタミンb5を生産するための方法 Download PDFInfo
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- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
- C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
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- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
- C12Y104/01021—Aspartate dehydrogenase (1.4.1.21)
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- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- C12R2001/19—Escherichia coli
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- C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
- C12Y104/01—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with NAD+ or NADP+ as acceptor (1.4.1)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210214588.5 | 2022-03-07 | ||
| CN202210214588.5A CN115595314B (zh) | 2022-03-07 | 2022-03-07 | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
| PCT/CN2023/076669 WO2023169176A1 (zh) | 2022-03-07 | 2023-02-17 | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025516089A true JP2025516089A (ja) | 2025-05-27 |
| JP2025516089A5 JP2025516089A5 (https=) | 2025-12-12 |
Family
ID=84841728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024553524A Pending JP2025516089A (ja) | 2022-03-07 | 2023-02-17 | アスパラギン酸デヒドロゲナーゼを発現する遺伝子組換え細菌、及び発酵によってビタミンb5を生産するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20260002182A1 (https=) |
| EP (1) | EP4458960A1 (https=) |
| JP (1) | JP2025516089A (https=) |
| CN (1) | CN115595314B (https=) |
| WO (1) | WO2023169176A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115595328B (zh) * | 2022-03-07 | 2026-02-13 | 中国科学院微生物研究所 | 天冬氨酸脱羧酶在发酵生产维生素b5中的应用 |
| CN115595314B (zh) * | 2022-03-07 | 2025-06-24 | 中国科学院微生物研究所 | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
| CN116024278B (zh) * | 2022-12-16 | 2024-05-07 | 黑龙江新和成生物科技有限公司 | 一种发酵法制备d-泛酸的方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100421088B1 (ko) * | 1995-09-13 | 2004-06-04 | 바스프 악티엔게젤샤프트 | 디-판토산및디-판토텐산또는그의염의생성방법 |
| DE19855314A1 (de) * | 1998-12-01 | 2000-06-08 | Degussa | Verfahren zur fermentiven Herstellung von D-Pantothensäure unter Verwendung von Stämmen der Familie Enterobacteriaceae |
| EP2163629B1 (en) * | 1999-09-21 | 2017-03-08 | Basf Se | Methods and microorganisms for production of panto-compounds |
| CA2491145A1 (en) * | 2002-07-03 | 2004-01-15 | Basf Aktiengesellschaft | Microorganisms and processes for enhanced production of pantothenate |
| JP2004254544A (ja) * | 2003-02-25 | 2004-09-16 | Ajinomoto Co Inc | 新規リジンデカルボキシラーゼ遺伝子及びl−リジンの製造法 |
| CN108728470B (zh) * | 2017-04-14 | 2022-01-11 | 中国科学院微生物研究所 | 产β-丙氨酸的重组菌及其构建方法与应用 |
| CN109306343A (zh) * | 2017-07-26 | 2019-02-05 | 中国科学院微生物研究所 | 新型天冬氨酸脱氢酶及在天冬氨酸族氨基酸生产上的应用 |
| CN112625985B (zh) * | 2020-12-04 | 2022-05-31 | 浙江工业大学 | 一种高产β-丙氨酸的基因工程菌及共培养制备D-泛酸 |
| CN115595328B (zh) * | 2022-03-07 | 2026-02-13 | 中国科学院微生物研究所 | 天冬氨酸脱羧酶在发酵生产维生素b5中的应用 |
| CN115595314B (zh) * | 2022-03-07 | 2025-06-24 | 中国科学院微生物研究所 | 表达天冬氨酸脱氢酶的工程菌及发酵生产维生素b5的方法 |
-
2022
- 2022-03-07 CN CN202210214588.5A patent/CN115595314B/zh active Active
-
2023
- 2023-02-17 WO PCT/CN2023/076669 patent/WO2023169176A1/zh not_active Ceased
- 2023-02-17 EP EP23765754.9A patent/EP4458960A1/en active Pending
- 2023-02-17 JP JP2024553524A patent/JP2025516089A/ja active Pending
- 2023-02-17 US US18/841,611 patent/US20260002182A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN115595314B (zh) | 2025-06-24 |
| WO2023169176A1 (zh) | 2023-09-14 |
| EP4458960A1 (en) | 2024-11-06 |
| CN115595314A (zh) | 2023-01-13 |
| US20260002182A1 (en) | 2026-01-01 |
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