CN1155399A

CN1155399A - Natural anti-cancer and health-care beverage

Info

Publication number: CN1155399A
Application number: CN 96100704
Authority: CN
Inventors: 张灵
Original assignee: Individual
Current assignee: Individual
Priority date: 1996-01-25
Filing date: 1996-01-25
Publication date: 1997-07-30

Abstract

An anti-cancer beverage is prepared from cephalotaxine, enqlish yew phenol, actinidine and white sugar, and serves both as health-care beverage and to prevent and cure cancers.

Description

Natural anti-cancer health drink Shanmilu and compound method thereof

The invention belongs to a kind of health drink, particularly in a kind of beverage that extracts in natural plants with anticancer health-care effect.

Both at home and abroad natural anti-cancer drugs was extracted quite in recent years and paid attention to, country such as the U.S., Japan, Italy is at the brilliant product of 600 kilograms of taxols of the annual buying of China, every gram purity is 98.5% crystalline substance product, and price in the international market reaches 6,000 yuan to 12,000 yuans.Yet, in state-owned a large amount of plant resourceses, but Shang Weiyou is made into tablet or injection, have to be with the foreigner's medicine and got the patient of leukaemia, tumour.

Cepehalotaxus fortunei, Chinese yew and three kinds of natural plants of Kiwi berry, just on the books as far back as dynasties such as the Chinese, Song, units, can be used to prevent and treat the morbidity of asexual tumour, and effects such as heat-clearing, detoxifcation, anti-inflammatory, pain relieving are arranged, cure mainly pernicious, benign tumour.

The objective of the invention is to overcome problems of the prior art, propose a kind of natural anti-cancer health drink,, make a kind of cancer-prevention healthcare beverage extracting the composition of cancer-preventing health in sharp China fir, Chinese yew and three kinds of natural plants of Kiwi berry.

The key component and the weight thereof of natural anti-cancer health drink Shanmilu of the present invention are respectively:

Tricuspid sugi gum alkali 10g, Chinese yew phenol 1-2g, the high-alkali 10-15g of Kiwi berry, white sugar 10-15g, distilled water 100kg.

Wherein the purity of each component is respectively: tricuspid sugi gum alkali 80%, Chinese yew phenol and Kiwi berry are high-alkali to be 98%.

The technical process of natural anti-cancer health drink Shanmilu of the present invention is:

1, batching: tricuspid sugi gum alkali, Chinese yew, Kiwi berry is high-alkali, white sugar proportions with distilled water and stirs evenly into mixed liquor;

2, filter: above-mentioned mixed liquor is poured in the glass diafiltration bottle (about 1m height, diameter are 12cm) that absorbent cotton and filter paper are housed filtered;

3, evaporation: again filtrate is placed in the stainless steel evaporator and steams three times continuously, and reclaim distilled water with the glass cools device;

4, precipitation: in distilled water, add about 0.5% alum powder, precipitate about 10 days after, the liquid of gained is anticancer health-care beverage Shanmilu.

The component tricuspid sugi gum alkali extraction process of Shanmilu of the present invention is:

1, pulverize to soak: with the dry product of cepehalotaxus fortunei, pulverize and cross 60 mesh sieves as branch, leaf, fruit etc., per hundred kilograms of sieve powder are with immersion 4-6 days in watt cylinder of 300 kilograms of 95% ethanol;

2, filter evaporation: soak is filtered with 120 purpose talcum sand, and drip filter with the degreasing sheepskin, the glass round-bottomed flask that filtrate is risen at 5000-10000 is placed on evaporation recovery ethanol in 80 ℃ of hot water again;

3, add heat decoloring: the liquid of sloughing behind the ethanol becomes white after being heated to 30 ℃ of decolourings with active carbon in the flask;

4, diafiltration drying: the white liquid of pouring out after the decolouring is put into glass diafiltration bottle (the high 1m that filter paper is housed, diameter 6cm) filters in, on the filter paper face, be placed with 80 purpose talcum powder, at last that percolate is dry under 60 ℃ temperature, get final product to such an extent that purity is the white powder of 80% tricuspid sugi gum alkali.

The component Chinese yew phenol extraction technology of Shanmilu of the present invention is:

1, pulverizes immersion: with the dry product of Chinese yew, be crushed to 20 powder materials,, in watt cylinder, soaked 2-4 days with 350 kilograms of the ethanol of per kilogram powder adding more than 95% as branch, leaf, sprouting etc.;

2, filter evaporation: soak is filtered with no mudstone sand, again filtrate is poured into round bottom glass flask (5000-10000 liter) and reclaim ethanol with 80 ℃ hot water evaporation;

3, quench and get precipitation: the liquid that reclaims behind the ethanol is poured into from bottle in watt cylinder, adds the ether of one times of amount of liquid again, stirs repeatedly to quench with rod and gets, and after 10-20 minute, quiescent setting 8-12 hour, emits the liquid ether of quenching;

4, filter exchange: the glass exchange column bottle of one kilogram of left and right sides discolour silica gel is housed (as high 1m in using, diameter is 8cm), the liquid of will quenching drips diafiltration by silica gel, also is placed with the activated carbon of about 5 money on the layer of silica gel in bottle, again phenol has been exchanged in silica gel after can decolouring like this, reclaimed ether;

5, clean and to dry in the shade: will reclaim silica gel behind the ether with 15-20 ℃ warm water cleaning silica gel, and till wash water Clear and Bright, then silica gel be dried in the shade;

6, drip and ooze drying: the silica gel after drying in the shade is put into vial (as high 1m, diameter is 8cm) in, ethanol with 95% drips and oozes, 30 milliliters of per minutes, then percolate is placed in the round-bottomed bottle of thousand milliliters of 3-5, reclaims ethanol with the evaporation of 75 ℃ hot water, the liquid that will reclaim at last behind the ethanol is poured out, 15-20 ℃ down dry, get final product purity greater than 98% Chinese yew phenol white powder.

The high-alkali extraction process of component Kiwi berry in the Shanmilu of the present invention is:

1, pulverize to soak: it is 100 kilograms of 120 purpose powders that dry products such as the root of Kiwi berry, skin are pulverized, putting into 50 kilograms 40 ℃ the hot water that is added with 10 kilograms of glauber salt placed about 24 hours, again raw material is put in watt cylinder, ethanol with 85% soaked 30-40 hour for 350 kilograms, emit soak precipitation about 24 hours, emit limpid immersion liquid then;

2, diafiltration exchange: limpid immersion liquid is placed on the repeatedly backflow diafiltration of percolation vat (as the steel alloy percolation vat) through about 48 hours with 5 kilograms of discolour silica gels, and actinidine has exchanged in silica gel like this, and ethanol is reclaimed in evaporation in 90 ℃ of hot water again;

3, clean diafiltration: clean repeatedly with refrigerant water through silica gel, directly fall limpid till, clean silica gel is placed under 15-20 ℃ dries again, more dried silica gel is put in the percolation vat, drip with 75% ethanol and ooze, about 120 dropping liquids of per minute;

4, evaporation drying: the dropping liquid through accepting, in 5,000 milliliters round bottom vial, ethanol is reclaimed in evaporation in 80 ℃ of temperature, and the article that reclaim behind the ethanol are dry under 15-20 ℃ of temperature, get final product to such an extent that purity reaches the high-alkali white powder of Kiwi berry more than 98%.

Shanmilu of the present invention proves through 600 many cases clinical testings such as Mianning County hospital, first and second hospital of state, the Liangshan Mountain, Panzhihua 410 hospitals, leukaemia, non-scrofula, pernicious and benign tumour there are effect unique, diseases such as lung cancer, liver cancer, intestinal cancer, the cancer of the uterus, cutaneum carcinoma are also had certain effect.And through the chemical examination of sanitary inspection unit, this product is the pure natural plant preparation, has no side effect, and promptly is a kind of health drink, again anti-curing cancers and tumour is had a significant effect.

Embodiment:

With 10g cephalotaxine fat, 1.5g Chinese yew phenol, the 12g Kiwi berry is high-alkali, the distilled water of 13g white sugar and 100kg mixes to mix well puts into the high 1m that absorbent cotton and filter paper are housed, diameter is to filter in the glass filter flask of 12cm, reclaim distilled water with the glass cools device after filtrate being put into stainless steel evaporator continuous evaporation three times again, add 0.5% alum powder precipitation then after 10 days in distilled water, the liquid of gained is Shanmilu of the present invention.

Claims

1, a kind of natural anti-cancer health drink is characterized in that its key component and weight thereof are respectively: tricuspid sugi gum alkali 10g, Chinese yew phenol 1-2g, the high-alkali 10-15g of Kiwi berry, white sugar 10-15g, distilled water 100kg.

2, a kind of compound method of natural anti-cancer health drink the steps include:

1), high-alkali, the white sugar of tricuspid sugi gum alkali, Chinese yew, Kiwi berry proportions with distilled water and stirs evenly into mixed liquor;

2), filter: above-mentioned mixed liquor is poured in the glass diafiltration bottle that absorbent cotton and filter paper are housed filtered;

3), evaporation: again filtrate is placed in the stainless steel evaporator and steams three times continuously, and reclaim distilled water with the glass cools device;

4), precipitation: in distilled water, add about 0.5% alum powder, precipitate about 10 days after, the liquid of gained is anticancer health-care beverage Shanmilu.

3, method as claimed in claim 2 is characterized in that preparation method's step of described tricuspid sugi gum alkali is:

1), pulverize to soak: with the dry product of cepehalotaxus fortunei, pulverize and cross 60 mesh sieves as branch, leaf, fruit etc., per hundred kilograms of sieve powder are with immersion 4-6 days in watt cylinder of 300 kilograms of 95% ethanol;

2), filter evaporation: filter with 120 purpose talcum sand through soak, and drip filter with the degreasing sheepskin, the glass round-bottomed flask that filtrate is risen at 5000-10000 is placed on evaporation recovery ethanol in 80 ℃ of hot water again;

3), add heat decoloring: the liquid of sloughing behind the ethanol becomes white after being heated to 30 ℃ of decolourings with active carbon in the flask;

4), diafiltration drying: pour out white liquid after the decolouring and put into the glass diafiltration bottle that filter paper is housed and filter, on the filter paper face, be placed with 80 purpose talcum powder powder.At last that percolate is dry under 60 ℃ temperature, get final product to such an extent that purity is the white powder of 80% tricuspid sugi gum alkali.

4, method as claimed in claim 2, its feature in preparation method's step of doing described Chinese yew phenol is:

1), pulverizes and soak: with the dry product of Chinese yew, be crushed to 20 powder materials,, in watt cylinder, soaked 2-4 days with 350 kilograms of the ethanol of per kilogram powder adding more than 95% as branch, leaf, sprouting etc.;

2), filter evaporation: soak is filtered with no mudstone sand, again filtrate is poured into the hot water with 80 ℃ evaporates recovery ethanol in the round bottom glass flask;

3), quench and get precipitation: the liquid behind the recovery ethanol is poured into from bottle in watt cylinder, adds the ether of one times of amount of liquid again, stirs repeatedly to quench with rod and gets, and after 10-20 minute, quiescent setting 8-12 hour, emits the liquid ether of quenching;

4), filter exchange: the glass exchange column bottle of one kilogram of left and right sides discolour silica gel is housed in using, and the liquid of will quenching drips diafiltration by silica gel, also is placed with the activated carbon of about 5 money on the layer of silica gel in bottle, phenol has been exchanged in silica gel after can decolouring so again, has reclaimed ether;

5), clean and to dry in the shade: will reclaim silica gel behind the ether with 15-20 ℃ warm water cleaning silica gel, and till wash water Clear and Bright, then silica gel be dried in the shade;

6), drip and to ooze drying: the silica gel after drying in the shade is put into vial, and the ethanol with 95% drips and oozes, and 30 milliliters of per minutes are placed on percolate in the round-bottomed bottle then, the hot water recovery ethanol with 75%, the liquid that will reclaim at last behind the ethanol is poured out.15-20 ℃ down dry, get final product purity greater than 98% Chinese yew phenol white powder.

5, the method described in claim 2 is characterized in that the high-alkali preparation method's step of described Kiwi berry is:

1), pulverize to soak: it is 100 kilograms of 120 purpose powders that dry products such as the root of Kiwi berry, skin are pulverized, putting into 50 kilograms 40 ℃ the hot water that is added with 10 kilograms of glauber salt placed about 24 hours, again raw material is put in watt cylinder, ethanol with 85% soaked 30-40 hour for 350 kilograms, emit soak precipitation about 24 hours, emit limpid immersion liquid then;

2), diafiltration exchange: limpid immersion liquid is placed on the repeatedly backflow diafiltration of percolation vat through about 48 hours with 5 kilograms of discolour silica gels, and actinidine is to have exchanged in silica gel like this, and ethanol is reclaimed in evaporation in 90 ℃ of hot water again;

3), clean diafiltration: clean repeatedly with refrigerant water through silica gel, directly fall limpid till, clean silica gel is placed under 15-20 ℃ dries again, more dried silica gel is put in the percolation vat, drip with 75% ethanol and ooze, about 120 dropping liquids of per minute;

4), evaporation drying: the dropping liquid through accepting, in the round bottom vial, ethanol is reclaimed in evaporation in 80 ℃ of temperature, the article that reclaim behind the ethanol are dry under 15-20 ℃ of temperature, get final product to such an extent that purity reaches the high-alkali white powder of Kiwi berry more than 98%.