CN1154511C - 表现抗过氧化作用对人器官引起的损伤的保护作用的水包油乳液及其生产和应用 - Google Patents

表现抗过氧化作用对人器官引起的损伤的保护作用的水包油乳液及其生产和应用 Download PDF

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Publication number
CN1154511C
CN1154511C CNB998147478A CN99814747A CN1154511C CN 1154511 C CN1154511 C CN 1154511C CN B998147478 A CNB998147478 A CN B998147478A CN 99814747 A CN99814747 A CN 99814747A CN 1154511 C CN1154511 C CN 1154511C
Authority
CN
China
Prior art keywords
tocopherol
emulsion
oil
content
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB998147478A
Other languages
English (en)
Chinese (zh)
Other versions
CN1331606A (zh
Inventor
U
U·艾根雷奇
涡��
N·菲奇丁格
G·霍弗
K·施奥普
÷
K·索莫梅尔
A·沃姆
E·纳盖尔
��ά��ɭ
A·梅尔祖维尔森多夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Kabi Austria GmbH
Original Assignee
Fresenius Kabi Austria GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fresenius Kabi Austria GmbH filed Critical Fresenius Kabi Austria GmbH
Publication of CN1331606A publication Critical patent/CN1331606A/zh
Application granted granted Critical
Publication of CN1154511C publication Critical patent/CN1154511C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cosmetics (AREA)
CNB998147478A 1998-12-21 1999-12-18 表现抗过氧化作用对人器官引起的损伤的保护作用的水包油乳液及其生产和应用 Expired - Lifetime CN1154511C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19859045A DE19859045A1 (de) 1998-12-21 1998-12-21 Emulsion vom Typ Öl in Wasser mit Schutzwirkung gegen Peroxidationsschäden an menschlichen Organen, deren Herstellung und Verwendung
DE19859045.8 1998-12-21

Publications (2)

Publication Number Publication Date
CN1331606A CN1331606A (zh) 2002-01-16
CN1154511C true CN1154511C (zh) 2004-06-23

Family

ID=7891978

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB998147478A Expired - Lifetime CN1154511C (zh) 1998-12-21 1999-12-18 表现抗过氧化作用对人器官引起的损伤的保护作用的水包油乳液及其生产和应用

Country Status (10)

Country Link
US (1) US6676956B1 (enExample)
EP (1) EP1140195B1 (enExample)
JP (1) JP4624564B2 (enExample)
CN (1) CN1154511C (enExample)
AT (1) ATE235254T1 (enExample)
DE (2) DE19859045A1 (enExample)
DK (1) DK1140195T3 (enExample)
ES (1) ES2192098T3 (enExample)
PT (1) PT1140195E (enExample)
WO (1) WO2000037108A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0515888A (pt) * 2004-09-24 2008-08-12 Lipo Chemicals Inc sistema de liberação, composição para aplicação tópica em pele ou pêlo de mamìfero, e, método para tratar pele de mamìfero
CN100525753C (zh) * 2005-11-15 2009-08-12 董英杰 辅酶q10亚微乳注射液及制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4950124A (enExample) * 1972-09-27 1974-05-15
JPS57163313A (en) * 1981-03-31 1982-10-07 Nippon Shinyaku Co Ltd Vitamin e pharmaceutical and its preparation
JPS58162517A (ja) * 1982-03-19 1983-09-27 Green Cross Corp:The 脂溶性ビタミン含有脂肪乳剤
IT1191608B (it) * 1985-02-01 1988-03-23 Zambon Spa Composizione farmaceutica e forme farmaceutiche che la contengono
US4678808A (en) * 1985-10-15 1987-07-07 Baxter Travenol Laboratories, Inc. Rapid acting intravenous emulsions of omega-3 fatty acid esters
JPH0262829A (ja) * 1988-05-18 1990-03-02 Nippon Kayaku Co Ltd 虚血に基づく傷害の予防及び治療剤
US5693337A (en) * 1994-07-13 1997-12-02 Wakamoto Pharmaceutical Co., Ltd. Stable lipid emulsion
GB9514878D0 (en) 1995-07-20 1995-09-20 Danbiosyst Uk Vitamin E as a solubilizer for drugs contained in lipid vehicles
DE19758157A1 (de) * 1997-03-27 1998-10-01 Sueddeutsche Kalkstickstoff Homogene, Glycerophospholipide und polare oder lipophile Substanzen enthaltende, wasserfreie Formulierungen und Verfahren zu deren Herstellung
US6630161B1 (en) * 1998-05-07 2003-10-07 Ribi Immunochem Research, Inc. Adjuvant composition and methods for its use

Also Published As

Publication number Publication date
CN1331606A (zh) 2002-01-16
EP1140195B1 (de) 2003-03-26
PT1140195E (pt) 2003-08-29
JP2002532564A (ja) 2002-10-02
WO2000037108A1 (de) 2000-06-29
ES2192098T3 (es) 2003-09-16
US6676956B1 (en) 2004-01-13
ATE235254T1 (de) 2003-04-15
EP1140195A1 (de) 2001-10-10
DE19859045A1 (de) 2000-06-29
DK1140195T3 (da) 2003-06-23
JP4624564B2 (ja) 2011-02-02
HK1037527A1 (en) 2002-02-15
DE59904788D1 (de) 2003-04-30

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SE01 Entry into force of request for substantive examination
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GR01 Patent grant
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CX01 Expiry of patent term

Granted publication date: 20040623