CN115444849B - 具有改善的防腐效力或光稳定性的眼科药物组合物 - Google Patents

具有改善的防腐效力或光稳定性的眼科药物组合物 Download PDF

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Publication number
CN115444849B
CN115444849B CN202211127527.1A CN202211127527A CN115444849B CN 115444849 B CN115444849 B CN 115444849B CN 202211127527 A CN202211127527 A CN 202211127527A CN 115444849 B CN115444849 B CN 115444849B
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China
Prior art keywords
pharmaceutically acceptable
acceptable salt
carteolol
composition
proper amount
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CN202211127527.1A
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English (en)
Chinese (zh)
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CN115444849A (zh
Inventor
长滨良治
近藤文雄
大八木优
平田雄树
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Otsuka Pharmaceutical Co Ltd
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Otsuka Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202211127527.1A 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物 Active CN115444849B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2016-162611 2016-08-23
JP2016162611 2016-08-23
CN201780049806.1A CN109641059B (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物
PCT/JP2017/029934 WO2018038102A1 (en) 2016-08-23 2017-08-22 Ophthalmic pharmaceutical composition with improved preservative effectiveness or light stability

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201780049806.1A Division CN109641059B (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物

Publications (2)

Publication Number Publication Date
CN115444849A CN115444849A (zh) 2022-12-09
CN115444849B true CN115444849B (zh) 2025-07-01

Family

ID=59812062

Family Applications (3)

Application Number Title Priority Date Filing Date
CN202211127527.1A Active CN115444849B (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物
CN202211126345.2A Pending CN115463130A (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物
CN201780049806.1A Active CN109641059B (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN202211126345.2A Pending CN115463130A (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物
CN201780049806.1A Active CN109641059B (zh) 2016-08-23 2017-08-22 具有改善的防腐效力或光稳定性的眼科药物组合物

Country Status (4)

Country Link
JP (3) JP7123034B2 (enExample)
CN (3) CN115444849B (enExample)
TW (4) TW202332446A (enExample)
WO (1) WO2018038102A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022131565A (ja) * 2021-02-26 2022-09-07 ロート製薬株式会社 水性医薬組成物
CN114788809B (zh) * 2022-01-25 2023-04-14 江苏广承药业有限公司 一种氯雷他定液体制剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772337B2 (en) * 2007-07-20 2014-07-08 Laboratoires Thea Preservative-free prostaglandin-based ophthalmic solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01135887A (ja) * 1987-11-20 1989-05-29 Lion Corp 紫外線吸収剤組成物
FR2777189B1 (fr) * 1998-04-09 2001-04-06 Chauvin Lab Sa Composition ophtalmique comprenant un beta-bloquant
JP4361294B2 (ja) * 2003-02-25 2009-11-11 ロート製薬株式会社 ケトチフェン含有組成物
JP5711957B2 (ja) * 2003-09-30 2015-05-07 ロート製薬株式会社 透明包装体入りトラニラスト含有医薬製剤
KR20060102282A (ko) * 2005-03-22 2006-09-27 테이카 세이야쿠 가부시키가이샤 점안제
US20070077302A1 (en) * 2005-09-30 2007-04-05 Azaam Alli Methods for stabilizing ophthalmic compositions
JP5661456B2 (ja) * 2008-04-23 2015-01-28 大塚製薬株式会社 点眼剤及び使用方法
CN101461780A (zh) 2009-01-06 2009-06-24 河北科技大学 不含抑菌剂的盐酸卡替洛尔滴眼液及其制备方法
TW201109325A (en) 2009-07-30 2011-03-16 Wakamoto Pharma Co Ltd Aqueous composition for eye drops
CN103079595B (zh) * 2010-08-27 2015-11-25 若素制药株式会社 滴眼用水性组合物
CN104136019A (zh) * 2012-02-27 2014-11-05 日本乐敦制药株式会社 眼科用组合物试剂盒

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772337B2 (en) * 2007-07-20 2014-07-08 Laboratoires Thea Preservative-free prostaglandin-based ophthalmic solution

Also Published As

Publication number Publication date
TW202513068A (zh) 2025-04-01
TWI814709B (zh) 2023-09-11
TW201811331A (zh) 2018-04-01
CN115444849A (zh) 2022-12-09
CN115463130A (zh) 2022-12-13
JP2022172124A (ja) 2022-11-15
JP7123034B2 (ja) 2022-08-22
JP2024112862A (ja) 2024-08-21
JP2019526549A (ja) 2019-09-19
TW202332446A (zh) 2023-08-16
TW202231276A (zh) 2022-08-16
CN109641059A (zh) 2019-04-16
CN109641059B (zh) 2022-08-30
TWI828025B (zh) 2024-01-01
WO2018038102A1 (en) 2018-03-01

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