CN115398210B - 光学测定装置及光学测定方法 - Google Patents

光学测定装置及光学测定方法

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Publication number
CN115398210B
CN115398210B CN202180026082.5A CN202180026082A CN115398210B CN 115398210 B CN115398210 B CN 115398210B CN 202180026082 A CN202180026082 A CN 202180026082A CN 115398210 B CN115398210 B CN 115398210B
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CN
China
Prior art keywords
light
signal
irradiation
detection
calibration
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CN202180026082.5A
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English (en)
Chinese (zh)
Other versions
CN115398210A (zh
Inventor
近藤房宣
岩田直树
松村朋和
竹下照雄
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Hamamatsu Photonics KK
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Hamamatsu Photonics KK
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Publication of CN115398210A publication Critical patent/CN115398210A/zh
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/8483—Investigating reagent band
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N2021/473—Compensating for unwanted scatter, e.g. reliefs, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756—Sensor type
    • G01N2021/7759—Dipstick; Test strip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN202180026082.5A 2020-04-01 2021-01-21 光学测定装置及光学测定方法 Active CN115398210B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020-066069 2020-04-01
JP2020066069A JP6931730B1 (ja) 2020-04-01 2020-04-01 光学測定装置及び光学測定方法
PCT/JP2021/002104 WO2021199605A1 (ja) 2020-04-01 2021-01-21 光学測定装置及び光学測定方法

Publications (2)

Publication Number Publication Date
CN115398210A CN115398210A (zh) 2022-11-25
CN115398210B true CN115398210B (zh) 2025-11-07

Family

ID=77549888

Family Applications (1)

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CN202180026082.5A Active CN115398210B (zh) 2020-04-01 2021-01-21 光学测定装置及光学测定方法

Country Status (7)

Country Link
US (1) US20230124819A1 (enExample)
EP (1) EP4123291A4 (enExample)
JP (2) JP6931730B1 (enExample)
KR (1) KR20220159971A (enExample)
CN (1) CN115398210B (enExample)
TW (1) TWI895383B (enExample)
WO (1) WO2021199605A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6923702B1 (ja) * 2020-04-01 2021-08-25 浜松ホトニクス株式会社 光学測定装置及び光学測定方法
TW202245178A (zh) 2021-01-21 2022-11-16 日商邦德科技股份有限公司 接合方法、接合裝置及接合系統
WO2024085899A1 (en) * 2022-10-19 2024-04-25 Wang ying ting Methods and apparatuses for fluorospectrometric measurements of low photon budget samples
TWI849658B (zh) * 2022-12-29 2024-07-21 致茂電子股份有限公司 複合式校正片

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WO1990009637A1 (en) * 1989-02-13 1990-08-23 Research Corporation Technologies, Inc. Method and means for parallel frequency acquisition in frequency domain fluorometry
JPH04106470A (ja) * 1990-08-28 1992-04-08 Hitachi Ltd 粒子免疫測定方法及びその装置
US5270548A (en) * 1992-07-31 1993-12-14 The United States Of America As Represented By The United States Department Of Energy Phase-sensitive flow cytometer
JP3483217B2 (ja) * 1994-02-08 2004-01-06 チノン株式会社 画像読取装置
JPH1151856A (ja) * 1997-08-07 1999-02-26 Nippon Telegr & Teleph Corp <Ntt> フォトリフレクタンスマッピング測定法
CA2310672A1 (en) * 1997-11-19 1999-05-27 University Of Washington High throughput optical scanner
US6251688B1 (en) * 1998-03-20 2001-06-26 Ia, Inc. Method and apparatus for measurement of binding between a protein and a nucleotide
JP2001137173A (ja) * 1999-11-11 2001-05-22 Fuji Photo Film Co Ltd 蛍光画像測定方法および装置
JP4660691B2 (ja) * 2005-04-08 2011-03-30 コニカミノルタセンシング株式会社 蛍光試料の光学特性測定方法及びこれを用いた光学特性測定装置
JP2010518394A (ja) 2007-02-06 2010-05-27 ナンヤン・テクノロジカル・ユニバーシティー 基板上に置かれた蛍光サンプルを分析するための装置および方法
US7630072B2 (en) * 2007-06-20 2009-12-08 Carestream Health, Inc. Fluorescence calibrator for multiple band flat field correction
JP5094484B2 (ja) * 2008-03-11 2012-12-12 富士フイルム株式会社 蛍光検出方法および蛍光検出装置
JP5239442B2 (ja) * 2008-03-25 2013-07-17 コニカミノルタオプティクス株式会社 蛍光試料の光学特性測定方法および装置
US20100032582A1 (en) * 2008-08-07 2010-02-11 General Electric Company Fluorescence detection system and method
CN102150035A (zh) * 2008-09-19 2011-08-10 三井造船株式会社 采用强度调制激光的荧光检测装置和荧光检测方法
JP5558178B2 (ja) * 2010-04-07 2014-07-23 オリンパス株式会社 蛍光観察装置
JP5487150B2 (ja) * 2011-03-31 2014-05-07 富士フイルム株式会社 光学的測定方法および光学的測定装置
JP2013200125A (ja) * 2012-03-23 2013-10-03 Mitsui Eng & Shipbuild Co Ltd 蛍光検出装置及び蛍光検出方法
JP5944843B2 (ja) * 2013-02-04 2016-07-05 浜松ホトニクス株式会社 分光測定装置及び分光測定方法
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TW201512648A (zh) * 2013-09-27 2015-04-01 Frank Jiann-Fu Yang 智慧型自動化化學物質定性及定量之檢測裝置及檢測方法
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Also Published As

Publication number Publication date
EP4123291A4 (en) 2024-04-24
WO2021199605A1 (ja) 2021-10-07
JP2021162509A (ja) 2021-10-11
KR20220159971A (ko) 2022-12-05
US20230124819A1 (en) 2023-04-20
TW202141022A (zh) 2021-11-01
JP7348933B2 (ja) 2023-09-21
TWI895383B (zh) 2025-09-01
JP6931730B1 (ja) 2021-09-08
EP4123291A1 (en) 2023-01-25
JP2021179447A (ja) 2021-11-18
CN115398210A (zh) 2022-11-25

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