CN115397838A - 溶瘤病毒样囊泡的组合物和使用方法 - Google Patents
溶瘤病毒样囊泡的组合物和使用方法 Download PDFInfo
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- CN115397838A CN115397838A CN202180020228.5A CN202180020228A CN115397838A CN 115397838 A CN115397838 A CN 115397838A CN 202180020228 A CN202180020228 A CN 202180020228A CN 115397838 A CN115397838 A CN 115397838A
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- C12N2770/36011—Togaviridae
- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
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- C12N2770/36111—Alphavirus, e.g. Sindbis virus, VEE, EEE, WEE, Semliki
- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36144—Chimeric viral vector comprising heterologous viral elements for production of another viral vector
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062959435P | 2020-01-10 | 2020-01-10 | |
| US62/959,435 | 2020-01-10 | ||
| PCT/US2021/012834 WO2021142366A1 (en) | 2020-01-10 | 2021-01-08 | Compositions and methods of use of oncolytic virus like vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115397838A true CN115397838A (zh) | 2022-11-25 |
Family
ID=74595378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180020228.5A Pending CN115397838A (zh) | 2020-01-10 | 2021-01-08 | 溶瘤病毒样囊泡的组合物和使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12577585B2 (https=) |
| EP (1) | EP4087858A1 (https=) |
| JP (1) | JP2023509966A (https=) |
| CN (1) | CN115397838A (https=) |
| WO (1) | WO2021142366A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024213051A1 (zh) * | 2023-04-11 | 2024-10-17 | 浙江自贸区红岸基地生物科技有限公司 | 一种saRNA递送系统及其制备方法和应用 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4460564A4 (en) * | 2022-01-08 | 2026-02-11 | Carogen Corp | MULTI-ANTIGEN THERAPEUTIC VACCINES TO TREAT OR PREVENT CHRONIC HEPATITIS B VIRUS INFECTION |
| JP2025508866A (ja) * | 2022-02-22 | 2025-04-10 | ヴァイロ バイオ インク. | 腫瘍溶解性ウイルスおよび使用方法 |
| CN119110727A (zh) * | 2022-02-22 | 2024-12-10 | 卡罗根公司 | 用于感染性疾病和癌症免疫疗法应用的多功能病毒样囊泡(vlv)平台 |
| US20260034208A1 (en) * | 2022-07-26 | 2026-02-05 | Yale University | Virus-like vesicles (vlvs) based vaccines and methods of preventing, ameliorating, and/or treating covid-19 and/or hepatocellular carcinoma (hcc) |
| IL320318A (en) * | 2022-10-19 | 2025-06-01 | Kalivir Immunotherapeutics Inc | Nucleic acids encoding tgf-beta inhibitor and il-12 and uses thereof |
| WO2024119388A1 (zh) * | 2022-12-07 | 2024-06-13 | 上海鑫湾生物科技有限公司 | 一种用于共表达多种目的基因的构建体及其用途 |
| WO2025208054A1 (en) * | 2024-03-28 | 2025-10-02 | Regeneron Pharmaceuticals, Inc. | Recombinant rhabdovirus encoding interleukin-12 (il-12) |
| CN120733012A (zh) * | 2024-08-20 | 2025-10-03 | 浙江大学 | 基于mRNA及蛋白编码的肿瘤药物、制备方法及应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008119827A1 (en) * | 2007-04-02 | 2008-10-09 | Fit Biotech Oy | Transreplicase constructs |
| CN106459997A (zh) * | 2014-05-16 | 2017-02-22 | 耶鲁大学 | 用于疫苗应用的高效价病毒样囊泡的进化 |
| WO2019057974A1 (en) * | 2017-09-22 | 2019-03-28 | Centre National De La Recherche Scientifique (Cnrs) | GLYCOPROTEIN MUTATED FROM VESICULAR STOMATITIS VIRUS |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1053751A1 (en) * | 1999-05-17 | 2000-11-22 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Compositions and methods for treating cell proliferation disorders |
| FR2862982B1 (fr) * | 2003-12-02 | 2006-04-28 | Genethon | Particules virales contenant un vecteur derive d'alpha-virus et procede de preparation de ladite particule virale. |
| ES2746960T3 (es) * | 2006-09-12 | 2020-03-09 | Alphavax Inc | Partículas de replicón de alfavirus que codifican IL-12 como adyuvantes inmunológicos |
| GB2460265A (en) * | 2008-05-23 | 2009-11-25 | Univ Dublin City | Detection assembly |
| AU2015259470A1 (en) | 2014-05-16 | 2016-11-10 | Yale University | Virus like vesicles (VLVs) based vaccines to prevent or treat chronic hepatitis B virus (HBV) infection |
| WO2017167317A1 (es) | 2016-03-31 | 2017-10-05 | Centro De Ingenieria Genetica Y Biotecnologia | Composición farmacéutica que comprende los antígenos de la superficie y de la nucleocápsida del virus de la hepatitis b |
| JP2019527737A (ja) * | 2016-08-09 | 2019-10-03 | アルケヤール, アルモハナッドALKAYYAL, Almohanad | Il12を発現する腫瘍溶解性ラブドウイルス |
-
2021
- 2021-01-08 EP EP21705306.5A patent/EP4087858A1/en active Pending
- 2021-01-08 WO PCT/US2021/012834 patent/WO2021142366A1/en not_active Ceased
- 2021-01-08 JP JP2022542209A patent/JP2023509966A/ja active Pending
- 2021-01-08 US US17/791,873 patent/US12577585B2/en active Active
- 2021-01-08 CN CN202180020228.5A patent/CN115397838A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008119827A1 (en) * | 2007-04-02 | 2008-10-09 | Fit Biotech Oy | Transreplicase constructs |
| CN106459997A (zh) * | 2014-05-16 | 2017-02-22 | 耶鲁大学 | 用于疫苗应用的高效价病毒样囊泡的进化 |
| WO2019057974A1 (en) * | 2017-09-22 | 2019-03-28 | Centre National De La Recherche Scientifique (Cnrs) | GLYCOPROTEIN MUTATED FROM VESICULAR STOMATITIS VIRUS |
Non-Patent Citations (2)
| Title |
|---|
| FAN JIA等: "Pseudo-typed Semliki Forest virus delivers EGFP into neurons", JOURNAL OF NEUROVIROLOGY, vol. 23, no. 2, 13 October 2016 (2016-10-13), pages 205 - 215, XP036182589, DOI: 10.1007/s13365-016-0486-8 * |
| TRACY D. REYNOLDS等: "Virus-Like Vesicle-Based Therapeutic Vaccine Vectors for Chronic Hepatitis B Virus Infection", JOURNAL OF VIROLOGY, vol. 89, no. 20, 5 August 2015 (2015-08-05), pages 10407 - 10415 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024213051A1 (zh) * | 2023-04-11 | 2024-10-17 | 浙江自贸区红岸基地生物科技有限公司 | 一种saRNA递送系统及其制备方法和应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2023509966A (ja) | 2023-03-10 |
| US12577585B2 (en) | 2026-03-17 |
| WO2021142366A1 (en) | 2021-07-15 |
| EP4087858A1 (en) | 2022-11-16 |
| US20230063041A1 (en) | 2023-03-02 |
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