CN115282218A - Herbal atomized composition for relieving eye fatigue and preparation method thereof - Google Patents

Herbal atomized composition for relieving eye fatigue and preparation method thereof Download PDF

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CN115282218A
CN115282218A CN202210741583.8A CN202210741583A CN115282218A CN 115282218 A CN115282218 A CN 115282218A CN 202210741583 A CN202210741583 A CN 202210741583A CN 115282218 A CN115282218 A CN 115282218A
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mass
herbal
traditional chinese
chinese medicine
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杨鹏
苏磊
唐泽龙
刘巍俊
胡旺顺
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Shenzhen Aipu Biotechnology Co ltd
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Shenzhen Aipu Biotechnology Co ltd
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Abstract

The application provides a herbal atomized composition for relieving eye fatigue and a preparation method thereof; the herbal atomized composition comprises the following components in parts by weight: 60-80 parts of alcohols, 1-3 parts of essence, 0.2-0.6 part of sweetener, 0.1-0.5 part of lutein, 0.1-0.5 part of vitamins and 2-6 parts of traditional Chinese medicine extract; wherein the traditional Chinese medicine extract is extracted from traditional Chinese medicines with the effect of protecting eyes. The application provides the herbal atomization composition has the effect of relieving eye fatigue, and can meet the health care requirement of a user on eyes.

Description

Herbal atomized composition for relieving eye fatigue and preparation method thereof
Technical Field
The application relates to the technical field of herbal atomization, in particular to a herbal atomization composition for relieving eye fatigue and a preparation method thereof.
Background
With the economic development and the improvement of living standard, people generally face sub-health problems while enjoying modern civilization achievements. According to the survey of the world health organization, the number of people really healthy is only 5 percent, the number of people suffering from diseases is 20 percent, and the rest 75 percent of people are in sub-health state. People in sub-health state are prone to feeling uncomfortable, fatigue, slow response, reduced vitality, reduced adaptability and the like.
At present, medical atomizers and aerosol inhalation preparations including traditional Chinese medicines become conventional tools for treating diseases such as respiratory tract diseases. Herbal atomization is a technology for dissolving micromolecule effective components obtained after the purification treatment of traditional herbal raw materials into atomized liquid and enabling the prepared herbal atomized liquid to be inhaled by a human body in an atomization mode on the basis of a new generation of atomization technology. Compared with other tobacco tar on the market, the herbal atomized liquid is healthier and harmless, and can be used for protecting the health of the electronic atomizer user better.
However, the herbal atomized liquid on the market at present has a single function, only can play a role in wetting the throat and clearing away the lung-heat, but does not have an effect of relieving eye fatigue, and is difficult to meet the health care requirements of users on eyes.
Disclosure of Invention
In view of the problems described, the present application is proposed to provide an herbal aerosolized composition for alleviating eye fatigue and a method for preparing the same, which overcomes or at least partially solves the problems described above, comprising:
a herbal atomization composition for relieving eye fatigue comprises the following components in parts by weight: 60-80 parts of alcohols, 1-3 parts of essence, 0.2-0.6 part of sweetener, 0.1-0.5 part of lutein, 0.1-0.5 part of vitamins and 2-6 parts of traditional Chinese medicine extract; wherein the traditional Chinese medicine extract is extracted from traditional Chinese medicines with the effect of protecting eyes; the Chinese medicinal materials include at least one of semen Cassiae, flos Chrysanthemi Indici, fructus Lycii, herba Taraxaci, grape seed, folium Mori, flos Eriocauli, periostracum Cicadae and Concha Margaritifera.
Preferably, the vitamins include at least one of riboflavin, vitamin C and vitamin E.
Preferably, the vitamin substances comprise the following components in parts by mass: 1-1.5 parts of riboflavin, 2-3 parts of vitamin C and 1-1.5 parts of vitamin E.
Preferably, the traditional Chinese medicine comprises the following components in parts by weight: 10-20 parts of cassia seed, 10-20 parts of wild chrysanthemum flower, 10-20 parts of wolfberry fruit, 5-10 parts of dandelion, 5-10 parts of grape seed, 5-10 parts of mulberry leaf, 5-10 parts of pipewort, 5-10 parts of cicada slough and 5-10 parts of mother of pearl.
Preferably, the alcohol substance comprises the following components in parts by weight: 45-80 parts of propylene glycol and 1-30 parts of glycerol.
Preferably, the essence comprises at least one of vanillin, ethyl maltol, citronellol, ethyl acetate, geraniol, linalool, rhodinol, beta-damascenone and benzyl alcohol.
Preferably, the sweetener comprises at least one of neotame and sucralose.
A process for the preparation of an herbal aerosolized composition according to any preceding claim, comprising:
adding an extraction solvent into the crushed traditional Chinese medicines, mixing, soaking and refluxing to obtain a traditional Chinese medicine extracting solution;
filtering and concentrating the traditional Chinese medicine extracting solution to obtain the traditional Chinese medicine extract;
uniformly stirring 60-80 parts by mass of the alcohol substance, 1-3 parts by mass of the essence, 0.2-0.6 part by mass of the sweetener, 0.1-0.5 part by mass of the lutein, 0.1-0.5 part by mass of the vitamin substance and 2-6 parts by mass of the traditional Chinese medicine extract to obtain the herbal atomized composition.
Preferably, the extraction solvent comprises a C2-C5 alcohol and water; wherein the volume ratio of the C2-C5 alcohol to the water is 1.
Preferably, the mass ratio of the traditional Chinese medicine to the extraction solvent is 1.
The application has the following advantages:
in the embodiment of the application, 60 to 80 parts of alcohol substances, 1 to 3 parts of essence, 0.2 to 0.6 part of sweetener, 0.1 to 0.5 part of lutein, 0.1 to 0.5 part of vitamin substances and 2 to 6 parts of traditional Chinese medicine extract are used as raw materials; the traditional Chinese medicine extract is extracted from a traditional Chinese medicine with an eye protection effect, so that the herbal atomized composition has the effect of relieving eye fatigue, and the health care requirement of a user on eyes can be met.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, the present application is described in further detail with reference to the following embodiments. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments in the present application without making any creative effort belong to the protection scope of the present application.
It should be noted that in any of the examples herein, the herbal aerosolized composition is applied to a low temperature nebulizer that produces an aerosol at 65 ℃, such as an ultrasonic nebulizer, a compression nebulizer, and the like. The low temperature atomizer not only has better atomizing function, can avoid simultaneously effective substance among the herbaceous atomizing composition loses efficacy because of pyrolysis.
In an embodiment of the application, a herbal atomized composition for relieving eye fatigue is provided, which comprises the following components in parts by weight: 60-80 parts of alcohols, 1-3 parts of essence, 0.2-0.6 part of sweetener, 0.1-0.5 part of lutein, 0.1-0.5 part of vitamins and 2-6 parts of traditional Chinese medicine extract; wherein the traditional Chinese medicine extract is extracted from traditional Chinese medicines with the effect of protecting eyes.
In the embodiment of the application, 60-80 parts of alcohol substances, 1-3 parts of essence, 0.2-0.6 part of sweetener, 0.1-0.5 part of lutein, 0.1-0.5 part of vitamin substances and 2-6 parts of traditional Chinese medicine extract are used; the traditional Chinese medicine extract is extracted from a traditional Chinese medicine with an eye protection effect, so that the herbal atomized composition has the effect of relieving eye fatigue, and the health care requirement of a user on eyes can be met.
An herbal aerosolized composition for alleviating eye fatigue in the present exemplary embodiment will be further described below.
In this embodiment, the vitamin substances include at least one of riboflavin, vitamin C, and vitamin E, and preferably riboflavin, vitamin C, and vitamin E. The riboflavin is also called as vitamin B2, is a component of the prosthetic group of the internal enzymes (the xanthase plays a hydrogen transfer role in biological oxidation reduction), when the riboflavin is deficient, the biological oxidation of the organism is influenced, the metabolism is disturbed, and the pathological changes of the riboflavin are mostly expressed by inflammation of the oral, ocular and external genitalia parts, such as angular cheilitis, glossitis, conjunctivitis, scrotitis and the like, so the riboflavin can be used for preventing and treating the diseases. The vitamin C has the effects of resisting oxidation, improving immunity, preventing aging, resisting respiratory tract infectious diseases, and reducing incidence of common cold. The vitamin E can regulate the hormone of a human body and is also one of important antioxidants.
In this embodiment, the vitamin substances include the following components in parts by mass: 1-1.5 parts of riboflavin, 2-3 parts of vitamin C and 1-1.5 parts of vitamin E. The vitamin substances are combined according to the proportion, so that the effects of relieving eye fatigue and promoting eye health can be realized.
In this embodiment, the Chinese herbal medicine includes at least one of cassia seed, wild chrysanthemum flower, wolfberry fruit, dandelion, grape seed, mulberry leaf, pipewort, cicada slough and mother-of-pearl, preferably cassia seed, wild chrysanthemum flower, wolfberry fruit, dandelion, grape seed, mulberry leaf, pipewort, cicada slough and mother-of-pearl. The semen Cassiae has effects of removing liver fire, improving eyesight, and loosening bowel to relieve constipation. The flos Chrysanthemi Indici has effects of clearing heat, detoxicating, calming liver and improving eyesight. The fructus Lycii has effects of nourishing liver and kidney, replenishing vital essence, improving eyesight, moistening lung, and relieving cough. The herba Taraxaci has effects of clearing away heat and toxic materials, resolving carbuncle, resolving hard mass, and resisting virus. The grape seed has effects of resisting oxidation, improving blood pressure and blood lipid, and protecting brain. The folium Mori has effects of dispelling pathogenic wind, clearing heat, removing liver fire, improving eyesight, cooling blood, and stopping bleeding. The flos Eriocauli has effects of dispelling pathogenic wind and heat, improving eyesight and removing nebula. The periostracum Cicadae has effects of dispelling pathogenic wind heat, dispelling toxic substance, promoting eruption, improving eyesight, removing nebula, dispelling pathogenic wind, and relieving spasm. The Concha Margaritifera has effects of suppressing hyperactive liver, subsiding yang, removing liver fire, improving eyesight, tranquilizing mind.
In the embodiment, the traditional Chinese medicine comprises the following components in parts by mass: 10-20 parts of cassia seed, 10-20 parts of wild chrysanthemum flower, 10-20 parts of medlar, 5-10 parts of dandelion, 5-10 parts of grape seed, 5-10 parts of mulberry leaf, 5-10 parts of pipewort, 5-10 parts of cicada slough and 5-10 parts of mother-of-pearl. According to the embodiment, the traditional Chinese medicines with the eye protection effect are selected according to the theory of traditional Chinese medicine and combined according to a specific proportion, so that the herbal atomized composition has the effect of relieving eye fatigue; the direct inhalation through the nebulization process improves the medication comfort and allows a rapid onset of efficacy.
In this embodiment, the alcohol substance comprises the following components in parts by mass: 45-80 parts of propylene glycol and 1-30 parts of glycerol. Preferably, the propylene glycol and the glycerol are both food grade or pharmaceutical grade products. The propylene glycol is an important solvent for improving the working stability of the herbal aerosolized composition. The glycerol can increase the viscosity and improve the aerosol state after atomization.
In this embodiment, the essence includes at least one of vanillin, ethyl maltol, citronellol, ethyl acetate, geraniol, linalool, rhodinol, β -damascenone, and benzyl alcohol. The aroma and mouthfeel of the herbal aerosolized composition may be further adjusted by the fragrance.
In this embodiment, the sweetener comprises at least one of neotame and sucralose. Through adopting have high sweetness and the sweet natural the neotame with sucralose carries out the compounding, is favorable to improving the smoking experience of herbaceous atomizing composition.
In an embodiment of the present application, there is also provided a method for preparing an herbal aerosolized composition according to any one of the above embodiments, comprising:
adding an extraction solvent into the crushed traditional Chinese medicines, mixing, soaking and refluxing to obtain a traditional Chinese medicine extracting solution;
filtering and concentrating the traditional Chinese medicine extracting solution to obtain the traditional Chinese medicine extract;
uniformly stirring 60-80 parts by mass of the alcohol substance, 1-3 parts by mass of the essence, 0.2-0.6 part by mass of the sweetener, 0.1-0.5 part by mass of the lutein, 0.1-0.5 part by mass of the vitamin substance and 2-6 parts by mass of the traditional Chinese medicine extract to obtain the herbal atomized composition.
The preparation method of the herbal atomized composition is simple to operate, and the activity of each component in the lutein, the vitamin substances and the traditional Chinese medicine extract can be effectively reserved.
In this embodiment, the extraction solvent comprises a C2-C5 alcohol and water; wherein the volume ratio of the C2-C5 alcohol to the water is 1. The C2-C5 alcohol is at least one of ethanol, propanol, butanol and pentanol. Preferably, the extraction solvent comprises the ethanol and the water, wherein the ethanol is 75-100% by volume.
In the embodiment, the mass ratio of the traditional Chinese medicine to the extraction solvent is 1; the soaking operation time is 2-4 hours; the time of the reflux operation is 4 to 8 hours.
In this embodiment, the filtering operation is performed by using a buchner funnel, the concentrating operation is performed by vacuum concentration, and the volume of the filtered filtrate is reduced to 1/10 of the original volume.
Example one
Weighing 10 parts by mass of semen cassiae, 10 parts by mass of wild chrysanthemum, 10 parts by mass of fructus lycii, 5 parts by mass of dandelion, 5 parts by mass of grape seeds, 5 parts by mass of mulberry leaves, 5 parts by mass of pipewort, 5 parts by mass of periostracum cicada and 5 parts by mass of mother-of-pearl, cleaning, crushing by using a crusher, adding a mixed solution of ethanol and water with the volume content of 90% of ethanol into a flask according to the mass ratio of 1.
Respectively adding 60 parts by mass of the alcohol substance, 1 part by mass of the essence, 0.2 part by mass of the sweetener, 0.1 part by mass of the lutein, 0.1 part by mass of the vitamin substance and 2 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance includes 45 parts by mass of propylene glycol and 1 part by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool, 1 part by mass of rhodinol, 1 part by mass of beta-damascenone and 1 part by mass of benzyl alcohol; the sweetener comprises 1 part by mass of neotame and 3 parts by mass of sucralose.
Example two
Weighing 15 parts by mass of semen cassiae, 15 parts by mass of wild chrysanthemum flower, 15 parts by mass of wolfberry fruit, 6 parts by mass of dandelion, 6 parts by mass of grape seed, 8 parts by mass of mulberry leaf, 8 parts by mass of pipewort, 8 parts by mass of periostracum cicada and 8 parts by mass of mother-of-pearl, cleaning, crushing by a crusher, adding a mixed solution of ethanol and water with the ethanol volume content of 90% into a flask according to the material liquid mass ratio of 1.
Respectively adding 70 parts by mass of the alcohol substance, 2 parts by mass of the essence, 04 parts by mass of the sweetener, 0.2 part by mass of the lutein, 0.3 part by mass of the vitamin substance and 3 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance comprises 60 parts by mass of propylene glycol and 20 parts by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool and 1 part by mass of rhodinol; the sweetener comprises 1 part by mass of neotame and 3 parts by mass of sucralose.
EXAMPLE III
Weighing 12 parts by mass of semen cassiae, 12 parts by mass of wild chrysanthemum flower, 12 parts by mass of wolfberry fruit, 6 parts by mass of dandelion, 6 parts by mass of grape seed, 6 parts by mass of mulberry leaf, 6 parts by mass of pipewort, 6 parts by mass of periostracum cicada and 6 parts by mass of mother-of-pearl, cleaning, crushing by a crusher, adding a mixed solution of ethanol and water with the ethanol volume content of 90% into a flask according to the material liquid mass ratio of 1.
Respectively adding 65 parts by mass of the alcohol substance, 1 part by mass of the essence, 0.2 part by mass of the sweetener, 0.2 part by mass of the lutein, 0.2 part by mass of the vitamin substance and 3 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance comprises 50 parts by mass of propylene glycol and 10 parts by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool, 1 part by mass of rhodinol, 1 part by mass of beta-damascenone and 1 part by mass of benzyl alcohol; the sweetener comprises 1 part by mass of neotame and 3 parts by mass of sucralose.
Example four
Weighing 18 parts by mass of semen cassiae, 18 parts by mass of wild chrysanthemum, 18 parts by mass of fructus lycii, 8 parts by mass of dandelion, 8 parts by mass of grape seeds, 8 parts by mass of mulberry leaves, 8 parts by mass of pipewort, 8 parts by mass of periostracum cicada and 8 parts by mass of mother-of-pearl, cleaning, crushing by a crusher, adding a mixed solution of ethanol and water with the volume content of 90% of ethanol into a flask according to the mass ratio of 1.
Respectively adding 75 parts by mass of the alcohol substance, 2 parts by mass of the essence, 0.2 part by mass of the sweetener, 0.1 part by mass of the lutein, 0.1 part by mass of the vitamin substance and 3 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance comprises 75 parts by mass of propylene glycol and 25 parts by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool, 1 part by mass of rhodinol, 1 part by mass of beta-damascenone and 1 part by mass of benzyl alcohol; the sweetener is neotame.
EXAMPLE five
Weighing 17 parts by mass of semen cassiae, 16 parts by mass of wild chrysanthemum, 19 parts by mass of fructus lycii, 7 parts by mass of dandelion, 6 parts by mass of grape seeds, 8 parts by mass of mulberry leaves, 8 parts by mass of pipewort, 7 parts by mass of periostracum cicada and 7 parts by mass of mother-of-pearl, cleaning, crushing by using a crusher, adding a mixed solution of ethanol and water with the volume content of 90% of ethanol into a flask according to the mass ratio of 1.
Respectively adding 78 parts by mass of the alcohol substance, 2 parts by mass of the essence, 0.6 part by mass of the sweetener, 0.4 part by mass of the lutein, 0.1-0.5 part by mass of the vitamin substance and 2 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance comprises 55 parts by mass of propylene glycol and 15 parts by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool and 1 part by mass of rhodinol; the sweetener is sucralose.
EXAMPLE six
Weighing 20 parts by mass of semen cassiae, 20 parts by mass of wild chrysanthemum, 20 parts by mass of fructus lycii, 10 parts by mass of dandelion, 10 parts by mass of grape seeds, 10 parts by mass of mulberry leaves, 10 parts by mass of pipewort, 10 parts by mass of periostracum cicada and 10 parts by mass of mother-of-pearl, cleaning, crushing by using a crusher, adding a mixed solution of ethanol and water with the volume content of 90% of ethanol into a flask according to the mass ratio of 1.
Respectively adding 80 parts by mass of the alcohol substance, 3 parts by mass of the essence, 0.6 part by mass of the sweetener, 0.5 part by mass of the lutein, 0.5 part by mass of the vitamin substance and 6 parts by mass of the traditional Chinese medicine extract into a clean reaction kettle, and uniformly stirring to obtain the herbal atomized composition; wherein the alcohol substance comprises 80 parts by mass of propylene glycol and 30 parts by mass of glycerin; the essence comprises 1 part by mass of vanillin, 1 part by mass of ethyl maltol, 1 part by mass of citronellol, 1 part by mass of ethyl acetate, 1 part by mass of geraniol, 1 part by mass of linalool, 1 part by mass of rhodinol, 1 part by mass of beta-damascenone and 1 part by mass of benzyl alcohol; the sweetener comprises 1 part by mass of neotame and 3 parts by mass of sucralose.
Comparative example 1
The same as example 1, except that the preparation of the chinese herbal medicine extract was not performed, and the lutein, the vitamin substances, and the chinese herbal medicine extract were not added.
Comparative example No. two
The same as example 3, except that the preparation of the chinese herbal medicine extract was not performed, and the lutein, the vitamin substances, and the chinese herbal medicine extract were not added.
Comparative example No. three
The same as example 6, except that the preparation of the chinese herbal medicine extract was not performed, and the lutein, the vitamin substances, and the chinese herbal medicine extract were not added.
Examples of the experiments
The herbal atomized compositions prepared by the preparation methods of examples one, three and six and comparative examples one, two and three are sequentially labeled as type 1, type 2, type 3, type 4, type 5 and type 6.
Selecting 300 volunteers (age 40-45 years) with the tobacco age of more than 10 years, randomly dividing 300 volunteers into 6 groups, wherein each group comprises 50 persons, the volunteers in the 1 st group smoke the herbal atomized composition in the 1 st group, the volunteers in the 2 nd group smoke the herbal atomized composition in the 2 nd group, the volunteers in the 3 rd group smoke the herbal atomized composition in the 3 rd group, the volunteers in the 4 th group smoke the herbal atomized composition in the 4 th group, the volunteers in the 5 th group smoke the herbal atomized composition in the 5 th group, the volunteers in the 6 th group smoke the herbal atomized composition in the 6 th group, and each volunteer smoke the herbal atomized composition in 80 mouths each day; the improvement of eye fatigue of each group of volunteers during the smoking period was continuously recorded, and the number of persons for each condition was recorded as shown in table 1.
Figure BDA0003718189970000091
Figure BDA0003718189970000101
TABLE 1
As can be seen from table 1, the eye health condition of the volunteers in groups 4 to 6 is not significantly improved, while the condition of the volunteers in groups 1 to 3 is significantly better than that of the volunteers in groups 4 to 6, and it is obvious that the herbal atomized composition provided by the present application can effectively alleviate the eye fatigue of the user by adding the lutein, the vitamins and the herbal extract.
While preferred embodiments of the present application have been described, additional variations and modifications of these embodiments may occur to those skilled in the art once they learn of the basic inventive concepts. Therefore, it is intended that the appended claims be interpreted as including the preferred embodiment and all changes and modifications that fall within the true scope of the embodiments of the present application.
Finally, it should also be noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "include", "including" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article, or terminal device including a series of elements includes not only those elements but also other elements not explicitly listed or inherent to such process, method, article, or terminal device. Without further limitation, an element defined by the phrases "comprising one of \ 8230; \8230;" does not exclude the presence of additional like elements in a process, method, article, or terminal device that comprises the element.
The herbal atomized composition for relieving eye fatigue and the preparation method thereof provided by the application are introduced in detail, and specific examples are applied to explain the principle and the implementation mode of the application, and the description of the examples is only used for helping to understand the method and the core idea of the application; meanwhile, for a person skilled in the art, according to the idea of the present application, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present application.

Claims (10)

1. The herbal atomization composition for relieving eye fatigue is characterized by comprising the following components in parts by weight: 60-80 parts of alcohols, 1-3 parts of essence, 0.2-0.6 part of sweetener, 0.1-0.5 part of lutein, 0.1-0.5 part of vitamins and 2-6 parts of traditional Chinese medicine extract; wherein the traditional Chinese medicine extract is extracted from traditional Chinese medicines with the effect of protecting eyes; the Chinese medicinal materials include at least one of semen Cassiae, flos Chrysanthemi Indici, fructus Lycii, herba Taraxaci, grape seed, folium Mori, flos Eriocauli, periostracum Cicadae and Concha Margaritifera.
2. The herbal atomizing composition of claim 1, wherein the vitamins include at least one of riboflavin, vitamin C, and vitamin E.
3. The herbal atomization composition as claimed in claim 2, wherein the vitamins comprise the following components in parts by mass: 1-1.5 parts of riboflavin, 2-3 parts of vitamin C and 1-1.5 parts of vitamin E.
4. The herbal atomization composition as claimed in claim 1, wherein the traditional Chinese medicine comprises the following components in parts by mass: 10-20 parts of cassia seed, 10-20 parts of wild chrysanthemum flower, 10-20 parts of wolfberry fruit, 5-10 parts of dandelion, 5-10 parts of grape seed, 5-10 parts of mulberry leaf, 5-10 parts of pipewort, 5-10 parts of cicada slough and 5-10 parts of mother of pearl.
5. The herbal atomized composition of claim 1, wherein the alcohol comprises the following components in parts by weight: 45-80 parts of propylene glycol and 1-30 parts of glycerol.
6. An herbal aerosolized composition as claimed in claim 1, wherein the perfume includes at least one of vanillin, ethyl maltol, citronellol, ethyl acetate, geraniol, linalool, rhodinol, β -damascone, and benzyl alcohol.
7. An herbal aerosolized composition as claimed in claim 1, characterised in that the sweetener includes at least one of neotame and sucralose.
8. A process for the preparation of herbal aerosolized composition of any one of claims 1-7, comprising:
adding an extraction solvent into the crushed traditional Chinese medicines, mixing, soaking and refluxing to obtain a traditional Chinese medicine extracting solution;
filtering and concentrating the traditional Chinese medicine extracting solution to obtain the traditional Chinese medicine extract;
uniformly stirring 60-80 parts by mass of the alcohol substance, 1-3 parts by mass of the essence, 0.2-0.6 part by mass of the sweetener, 0.1-0.5 part by mass of the lutein, 0.1-0.5 part by mass of the vitamin substance and 2-6 parts by mass of the traditional Chinese medicine extract to obtain the herbal atomized composition.
9. The method of claim 8, wherein the extraction solvent comprises a C2-C5 alcohol and water; wherein the volume ratio of the C2-C5 alcohol to the water is 1.
10. The preparation method according to claim 8, wherein the mass ratio of the traditional Chinese medicine to the extraction solvent is 1.
CN202210741583.8A 2022-06-28 2022-06-28 Herbal atomized composition for relieving eye fatigue and preparation method thereof Pending CN115282218A (en)

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716278A (en) * 2012-05-31 2012-10-10 苏学军 Eye ointment for improving eyesight
CN103417733A (en) * 2013-09-10 2013-12-04 南方医科大学 Medicine composition for relieving eyestrain
CN107279646A (en) * 2017-06-20 2017-10-24 刘忠波 Anti- eye fatigue chrysanthemum cream and preparation method thereof
CN107519338A (en) * 2016-06-22 2017-12-29 郑州市新视明科技工程有限公司 A kind of Chinese medicine composition of external application protection eyesight
CN108567910A (en) * 2017-03-13 2018-09-25 陕西新视明医药生物科技有限公司 The Chinese medicine composition of eye strain is alleviated in a kind of external application
CN108635461A (en) * 2018-06-11 2018-10-12 郑冬冬 Dry eyes atomized liquid
CN111450179A (en) * 2019-01-18 2020-07-28 任玉娟 Eyesight improving and eye protecting composition and application and preparation method thereof
CN113826894A (en) * 2021-08-30 2021-12-24 成都营养屋健康科技有限公司 Capsule for relieving visual fatigue and preparation method thereof
CN114366775A (en) * 2020-12-07 2022-04-19 慧眸国际生物科技(广东)有限公司 Eye-protecting nutrient solution

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102716278A (en) * 2012-05-31 2012-10-10 苏学军 Eye ointment for improving eyesight
CN103417733A (en) * 2013-09-10 2013-12-04 南方医科大学 Medicine composition for relieving eyestrain
CN107519338A (en) * 2016-06-22 2017-12-29 郑州市新视明科技工程有限公司 A kind of Chinese medicine composition of external application protection eyesight
CN108567910A (en) * 2017-03-13 2018-09-25 陕西新视明医药生物科技有限公司 The Chinese medicine composition of eye strain is alleviated in a kind of external application
CN107279646A (en) * 2017-06-20 2017-10-24 刘忠波 Anti- eye fatigue chrysanthemum cream and preparation method thereof
CN108635461A (en) * 2018-06-11 2018-10-12 郑冬冬 Dry eyes atomized liquid
CN111450179A (en) * 2019-01-18 2020-07-28 任玉娟 Eyesight improving and eye protecting composition and application and preparation method thereof
CN114366775A (en) * 2020-12-07 2022-04-19 慧眸国际生物科技(广东)有限公司 Eye-protecting nutrient solution
CN113826894A (en) * 2021-08-30 2021-12-24 成都营养屋健康科技有限公司 Capsule for relieving visual fatigue and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
国家食品药品监督管理总局 等, 中国医药科技出版社 *

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