CN1076616C - Pure natural health-care article for eliminating smoke harm - Google Patents
Pure natural health-care article for eliminating smoke harm Download PDFInfo
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Abstract
The present invention relates to a health care product which is composed of the extracts of tea leaf, licorice root, wolfberry fruit, astragalus root, Boat-fruited Scaphium Seed, hippophae rhamnoides fruit, mint, gingko and rice bran, wherein the extracts of the tea leaf, licorice root, wolfberry fruit, astragalus root, Boat-fruited Scaphium Seed, hippophae rhamnoides fruit, gingko and rice bran adopt a carbon dioxide supercritical or alcohol-water method for extraction, and other plant extracts can adopt market sale. All the components are quantitatively mixed, added into water or the mixture of alcohol and water, uniformly mixed, added with auxiliary materials required for a dosage form to be prepared and made into a finished product according to a conventional technology. The present invention can prevent and cure oral and respiratory diseases, pneumonectasis, asthma, lung cancer and throat cancer caused by smoking, can quickly dispel various kinds of odor in oral cavities, dental spots and can prevent dental calculus.
Description
The present invention relates to a kind of body-care preparation, refer to a kind of novel purely natural health product that can prevent, eliminate or reduce especially because of halitosis, tooth macula lutea, respiratory system disease and canceration that smoking causes.
Dirty air, the disease of oral cavity, throat, trachea, bronchus and pulmonary that virus, bacterial infection, especially smoking cause affects the healthy of modern day by day.These diseases comprise oral ulcer, laryngopharynx swelling and pain inflammation, trachea and bronchitis, emphysema, asthma, pulmonary carcinoma, laryngocarcinoma.The probability that the smoker suffers from pulmonary carcinoma, laryngocarcinoma and oral cancer is than high several times even tens times of the people of non-smoking.In addition, smoking also causes tooth smoking patch, dental calculus and halitosis.China has 300,000,000 smokers at present approximately, and the annual various diseases that causes because of smoking has not only had a strong impact on their healthy and operate as normal, and will expend a large amount of wealth and go to cure these diseases; For reducing the generation of above-mentioned disease, the present means of taking are substantially: advocate smoking cessation, reduce methods such as tobacco tar content.Therefore, if can invent and a kind ofly can cause that neither the smoker dislikes conflict, can effectively prevent the health product of harmfulness of smoking again, will produce huge economic benefit and social benefit.
The inventor is engaged in the research and development of the health product of preventing and curing diseases for many years always, feel that if can to invent a kind of health product or medicine that can prevent and cure the above-mentioned disease that causes because of smoking will be very necessary and significant deeply, then study intensively with great concentration, consult a large amount of Chinese medicine works, and combine the theory and the research method of modern biomedical, primary study the smog that produced during result of combustion of tobacco harm details to human body, thereby developed the pure natural prescription that overcomes these harm targetedly.Contain 4,000 kinds of harmful substances in the smog of result of combustion of tobacco, 40 kinds of carcinogen are wherein arranged, they are the arch-criminals that cause these diseases.Now several harmful substances that mainly contain are simply described as follows: (1) nicotine: can damage tunica mucosa tracheae, cause tracheobronchitis; Simultaneously, cerebrovascular is shunk strongly, reduce big cerebral oxygen supply, cause cerebrovascular disease; (2) carbon monoxide: bigger 300 times than oxygen with the binding ability of hemoglobin, oxygen is taken the photograph in strong influence, causes cardiovascular and cerebrovascular disease and dizziness; (3) tar: contain multiple carcinogen, and be attached to trachea, bronchus and alveolar surface, stimulate pulmonary to produce mucus, the tracheal cilia that has adhered to tar can't move again and discharge these harmful substances, thus vicious cycle; (4) benzopyrene: a kind of strong carcinogen that hereditary material DNA is morphed; (5) radioactive substance: the radiosiotope as aluminum (210), polonium (201) can cause cell carcinogenesis; (6) irritant compound: as cyaniding, formaldehyde and acrylic aldehyde etc.; (7) poisonous metal:, can cause asthma, emphysema as hydrargyrum, cadmium, nickel, arsenic etc.; (8) other poisonous carcinogen: as N-nitrosodimethylamine, Methylethyl nitrosamine etc.In addition,, find that living radical makes that hereditary material morphs in cell injury and the cell, thereby cause a series of diseases such as canceration along with the development of modern biomedical.And produce a large amount of living radicals in the cigarette combustion, and they directly suck in oral cavity, throat, respiratory tract and the lung, and badly damaged their endotheliocyte causes oral ulcer, laryngopharyngitis, respiratory inflammation and pulmonary carcinoma.
In the prior art, there is Chinese patent application to disclose with tea polyphenols and vitamin C (1: 1) in number 95116865.7 (publication number CN1145206A, open day on March 19th, 97) and joins in the cigarette filter, can remove free radical well.But the smoker is very fastidious to medicated cigarette taste and brand, and the smoker who enjoys this medicated cigarette is very little, and in addition, this medicated cigarette can not be removed other harmful substance beyond the free radical.Other has Chinese patent application number 9411840.1 (publication number CN1115616A, open day on January 31st, 1996) a kind of smokers health product and goods are disclosed in, it is the method with merceration or heating, extracts the mixture that contains active ingredient from plants such as DEN, IBS, Herb Gynostemmae Pentaphylli, Fructus Schisandrae Chinensis, Fructus Hippophae, Radix Glycyrrhizae, Pericarpium Citri Reticulatae, Fructus Crataegi, Fructus Mume, the Flos Sophorae Immaturus, green tea, Fructus Lycii, Folium Perillae, Fructus Foeniculi, Flos Caryophylli, Fructus Ligustri Lucidi, Semen Ziziphi Spinosae, Cortex Cinnamomi, Semen Raphani.It is indeterminate that the very complicated mixture of this composition must comprise curative effect, and certain toxic and side effects and impurity such as undesirable abnormal smells from the patient and taste are arranged, and can't realize the scientific quantitative compatibility.Therefore, its effect and difficult quality guarantee.
The objective of the invention is for overcoming the deficiencies in the prior art, by the known meticulous screening that the Chinese medicinal herbs plant of the function of well preventing and curing diseases arranged, utilization high-tech technological means essence being carried active ingredient and rationally composite to active ingredient in the plant, and then provide a kind of novel purely natural health product that can effectively prevent, eliminate or reduce because of halitosis, tooth macula lutea, respiratory system disease and canceration that smoking causes.
For this reason, the special health-care article for eliminating smoke harm of developing of the present invention with following two big characteristics:
1) utilizes high-tech plant extract technology (as carbon dioxide supercritical fluid extraction, chromatography etc.), extract the active ingredient in the natural plants such as Folium Camelliae sinensis, Radix Glycyrrhizae, Fructus Lycii, Semen Ginkgo, the Radix Astragali, Testa oryzae, Semen Sterculiae Lychnophorae and Fructus Hippophae, and these active ingredients are carried out reasonably composite, produce control above-mentioned disease highly effective health food.Because the present invention has abandoned traditional Chinese medicinal plant and only leached the method for crude extract with water alcohol, thereby have Chinese medicine west system, determined curative effect has no side effect, stay-in-grade characteristics.
2) according to Chinese medical theory and the pharmacological achievement in research of modern natral plant ingredients, other composition compatibility in astragalus polysaccharides that utilization is extracted from the Radix Astragali and astragaloside and the prescription, energy and tea polyphenols, tea catechin, lycium barbarum polysaccharide, Angelica Polysaccharide, glycyrrhizin etc. produce immune synergism, and immunocompetence is multiplied.
Concrete technical scheme of the present invention is: a kind of pure natural health-care article for eliminating smoke harm is characterized in that comprising in the component extracts of following plants: Folium Camelliae sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Semen Sterculiae Lychnophorae and Fructus Hippophae; Wherein said Folium Camelliae sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Semen Sterculiae Lychnophorae and Fructus Hippophae extract are to adopt CO 2 supercritical or the extractive method of pure water to extract; Compositions of the present invention adds uniform mixing in entry or the ethanol water mixture by quantitative compatibility, adds and desires the required necessary adjuvant of preparation type, makes finished product by the technology of this dosage form routine.
Described each plant extract is meant definite active component, and they are respectively: Folium Camelliae sinensis extract mainly is meant tea polyphenols, tea catechin and theophylline or removes the tea polyphenols of theophylline, the mixture of tea catechin; Radix Glycyrrhizae extract mainly is meant Angelica Polysaccharide and glycyrrhizin; Wolfberry fruit extract mainly is meant lycium barbarum polysaccharide; Radix Astragali extract mainly is meant astragalus polysaccharides and astragaloside; Semen Sterculiae Lychnophorae extract mainly is meant the Semen Sterculiae Lychnophorae polysaccharide; Fructus Hippophae extract mainly refers to contain the Oleum Hippophae of unsaturated aldehyde, unsaturated fatty acid, Ai Miliu lipidol class, vitamin C, vitamin E, beta-carotene.
Above-mentioned each component content is: 0.2-50% Folium Camelliae sinensis extract or Folium Camelliae sinensis remove the theophylline extract; The 0.1-20% Radix Glycyrrhizae extract; The 0.1-30% wolfberry fruit extract; The 0.1-20% Radix Astragali extract; The 0.3-5% Semen Sterculiae Lychnophorae extract; 0.1-15% Fructus Hippophae extract, surplus are pharmaceutical adjunct, and all percents are percetage by weight.
Optionally add Folium Menthae extract, Semen Ginkgo extrac and/or Testa oryzae extract in addition, wherein Semen Ginkgo extrac, Testa oryzae extract are to take the method for CO 2 supercritical or pure water extracting and chromatography to extract, and Folium Menthae extract is commercially available.Wherein each component content is: 0.1-5% Folium Menthae extract, 0.2-25% Semen Ginkgo extrac; 0.1-5% Testa oryzae extract; All percents are percetage by weight.
The Main Ingredients and Appearance of above-mentioned each plant extract is respectively: Semen Ginkgo extrac mainly is meant ginkgetin and ginkgolide; Folium Menthae extract mainly refers to Mentholum and Oleum menthae; The Testa oryzae extract mainly is meant rice bran polysaccharide (RBP) and lipids.
Can be added with the steviosin (weight meter) of 0.0001-0.01% in addition.
The present invention can be made into buccal tablet, confection, chewing gum, spray or aerosol, oral liquid, tablet or capsule formulation.
Carbon dioxide supercritical fluid extraction (CO among the present invention
2The SFE software that-SFE) technological process provides by Beijing supercritical fluid technology institute carries out.CO
2-SFE extracting method can be removed the oxious component in the plant, and for example, the Semen Ginkgo acids in the Semen Ginkgo is a toxic ingredient, can cause clonospasm, neural paralysis etc., and general extracting method Semen Ginkgo acids is residual about 2%, CO
2After-SFE extracted, the residual quantity of ginkgoic acid reached harmless degree less than 0.02%.Each kind of plant is through CO
2-SFE does not almost detect residual pesticide after extracting in its extract.In addition, CO
2Temperature is lower than 65 ℃ all the time in the-SFE leaching process, and its spe medium carbon dioxide is an inert substance, and to the readily oxidizable substance that will extract, especially materials such as antioxidant (vitamin C, vitamin E), unsaturated fatty acid play the effect of protection.Heavy metal pollution is to influence the main cause that Chinese medicine and Chinese medicine health care product are sold the America and Europe, and CO
2-SFE extraction method is to avoid the very effective method of heavy metal pollution.
Pure water extraction process of the present invention is undertaken by the general extraction process of Chinese medicine.
The pharmacological action of each component is described below respectively in the present invention's prescription:
Mentholum/Oleum menthae is used as oral cavity deodorant, clearing away lung-heat cough caused by dryness, anti-inflammatory analgetic, refrigerant tasty and refreshing effect with regard to record in " occupying diet with breath composes " in ancient times.
Folium Camelliae sinensis extract mainly is tea polyphenols, tea catechin and theophylline.Pharmacological research both domestic and external and clinical proof tea polyphenols and tea catechin have following effect: remove oxygen-derived free radicals and suppress lipid peroxidation (" Chinese Pharmacological Bulletin, He Bing etc., 1998,14 (3), 270-272); Prevent the variation of hereditary material in the cell, and anticancer (" Zhejiang Medical university journal ", 1997,26 (3), 97-99); Repair the cell of damage, mutation, radioprotective, blood fat reducing (" tumor ", 1996,16 (1), 46-49; " modern preventive medicine ", 1997,24 (3), 367-369); Suppress carcinogenic precursor compound and form termination cancer thing, the formation (" medicine thing daily paper " 1997,22 (9) 5 (days)) that suppresses to urge the cancer thing and block cancerous cell; Tea polyphenols acts on antibacterial, can solidify protein of bacteria, antibacterial is killed, to bacillary stomatitis, fester, laryngopharynx swelling and pain has certain curative effect; Theophylline has the effect of heart tonifying, spasmolytic, relaxing smooth muscle, can remove bronchospasm, and blood circulation promoting is the good ancillary drug of treatment bronchial asthma, relieving cough and resolving phlegm; Tea catechin can be removed tooth smoking patch and pre-dental calculus preventing effectively.
Semen Ginkgo extrac mainly is flavone and ginkgolide, inhibitory action to the carcinogenic startup factor (TPA) surpasses the retinoic acid with strong inhibition TPA, can remove free radical and suppress aging metabolite, ginkgolide can be prevented and treated emphysema, asthma effectively and become the poverty-stricken disease of human respiratory, oral cavity and respiratory tract to noxious substance damage in the medicated cigarette have significant repair (" modern Application pharmacy " 1995,12 (6) 5-9).
Semen Sterculiae Lychnophorae has the effect of heat-clearing and toxic substances removing, pharynx-clearing throat-benefiting in the traditional Chinese medical science.The pure water extract of Semen Sterculiae Lychnophorae can suppress xanthine oxidase, and when 100ppm, suppression ratio 80.6% has the effect of good inhibition tumor.
Radix Glycyrrhizae has relieving spasm to stop pain, moistening and cleaning throat in Chinese medicine, the effect of coordinating the actions of various ingredients in a prescription.Angelica Polysaccharide in the Radix Glycyrrhizae extract has antioxidation, immunomodulating, anti-inflammatory analgetic and anti-cancer, anticancer effect.Sweetener in its extract is lasting more, long-drawn-out lighter than sweet tastes such as sucrose, not damage tooth.
Fructus Lycii is cured record in the nationality " property of medicine opinion " at Gu: " the smart various symptoms and signs of deficiency of energy tonification, easily color bleaches, and makes eye bright, and calms the nerves." wolfberry fruit extract lycium barbarum polysaccharide (LBP) has following several function: 1. increase lymhocyte transformation rate and macrophage phagocytic function that immune function: LBP can improve laboratory animal; LBP has than strong selectivity immunity pharmacological reaction the T lymphocyte, can increase the quantity of T cell and strengthen that it is active and immune system is produced regulating action.LBP can also resist and remove the heavy metal that sucks in the lung, immunotoxicities such as tardy paraphilia reaction that the inhibition heavy metal causes and reduction antibody titer.Experiment shows that LBP can significantly improve the vigor of lysozyme in the oral cavity.2. antitumor: LBP has antimutagen, has to resist and block mutagenic action; LBP also has the effect of obvious suppression growth of cancer cells, breeding.3. LBP is to safeguarding the repair ability of cell normal development, raising DNA; promote senile cell, mutant to develop to rejuvenation, normalization: LBP can change the content of SOD in the blood, LPO and Hb; SOD raises 48%; Hb raises 12%; LPO then reduces by 65%, shows that LBP has the effect of very strong antioxidation, anti-cell aging.
The Testa oryzae extract is the mixture very widely of research both at home and abroad, has good antitumor and immunoregulatory effect.Rice bran polysaccharide (RBP) RBS wherein has the reticuloendothelial propagation function of enhancing, repairs the endotheliocyte that smoking damages, and in addition, furfural has the very strong effect that prevents and dispel halitosis.
The Main Ingredients and Appearance of Radix Astragali extract is astragalus polysaccharides and astragaloside, astragalus polysaccharides is had very strong immunoregulation effect by a large amount of animals and medical clinical test proof, not only self can produce a large amount of cellular immunization factors by stimulating immune system, and can produce immune synergism with above-mentioned tea polyphenols, tea catechin, lycium barbarum polysaccharide, Angelica Polysaccharide etc., their immunocompetence is multiplied.
The Fructus Hippophae extract Oleum Hippophae has following major function: 1. various cancers are all had the obvious suppression effect through modern medicine study and Tumour Inst., Chinese Medical Academy, a large amount of clinical verifications of Beijing Tumour Hospital; 2. be used for the treatment of multiple ulcer, as gastroduodenal ulcer, oral ulcer; 3. be used for the treatment of multiple inflammation, as pharyngolaryngitis, tonsillitis, periodontitis etc.; 4. but noxious substance is discharged in the acceleration bodies; 5. the pain to mucosal ulcer has analgesic effect.
Ratio among the present invention between each component is very important.Rationally the proper proportion relation just can be given full play to the effect of various components and the mutual synergism between the various component.If the improper effect of component ratio will reduce greatly.The present invention with Folium Camelliae sinensis extract as monarch drug, other composition with the monarch drug be main carry out composite.Collaborative pharmacology result after composite can be summarized as follows:
1) strong radical scavenging activity
Folium Camelliae sinensis extract, Radix Glycyrrhizae extract, wolfberry fruit extract, Fructus Hippophae extract, Testa oryzae are carried in the prescription
Get thing, Radix Astragali extract self all has free radical resisting oxidability preferably.But above-mentioned several
After the kind extract is rationally composite, its free radical resisting oxidability and protection cell mitochondrial liposome
The all remarkable oxidation resistance of peroxidation greater than independent extract.Test data of the present invention
As follows:
The A sample: (each percentages of ingredients is a weight percent to 100% Folium Camelliae sinensis extract in the sample
Ratio, as follows);
B sample: 100% Radix Astragali extract;
C sample: 70% Folium Camelliae sinensis extract+30% Radix Astragali extract;
The D sample: 50% Folium Camelliae sinensis extract+15% Radix Astragali extract+10% wolfberry fruit extract+10% is sweet
Grass extract+10% Fructus Hippophae extract+5% Testa oryzae extract.
Experiment is with reference to (" CHINA JOURNAL OF CHINESE MATERIA MEDICA " 1996,21 (12), 746-748 such as Shen Wenhai
" Acta Pharmacologica Sinica " 1994,10 (2) 129-132) adopts rat perfusion, sampling
Back ESR test free-radical contents.The result of free radical scavenging activity is that the A sample is 45.7%, B
Sample is 32.8%, and the C sample is 62.0%, and the D sample is 81.3%.Obviously, the Radix Astragali has one
Fixed cooperative effect.After each extract was composite, the clearance rate of free radical was greatly improved again.
2) strong immunostimulant ability
Hou Yun moral academician just finds that as far back as the eighties a small amount of Radix Astragali can improve interferon very significantly
Antiviral and immunocompetence, the Radix Astragali and immune system have a kind of special immunne response relation.
The present invention finds that equally also a spot of Radix Astragali extract can significantly strengthen the immunity of other extract
Ability.The sample of the present invention's experiment is composed as follows:
A sample: 100% Folium Camelliae sinensis extract;
B sample: 100% Radix Astragali extract;
C sample: 85% Folium Camelliae sinensis extract+15% Radix Astragali extract;
The D sample: 60% Folium Camelliae sinensis extract+15% Radix Astragali extract+5% wolfberry fruit extract+10% is sweet
Grass extract+10% Fructus Hippophae extract.
Experimental technique adopts popular in the world MTT (the blue azoles of thiazole bromide) staining, surveys
The apoptosis of examination gastric carcinoma cells (MGC).The attack concentration of each sample is 0.5mg/ml all, attacks
Hit 24 hours time, the apoptotic result of MGC is: A sample 18.8%, and B sample 8.2%,
C sample 33.1%, D sample 56.9%.This shows that Radix Astragali extract has significant cooperative effect.
Simultaneously, the anticancer effect of each extract after composite is desirable more.
Above-mentioned various component proves without any malicious pair and stimulation through a large amount of animals and clinical trial.
The present invention had once done 62 routine clinical trials and had observed.Laboratory sample is pressed following embodiment six preparations substantially.The sample of experiment is a smoking history more than 5 years, is condition more than one bag of smoking for each person every day.The results are shown in Table one: table one
This disease that shows that the present invention causes smoking has outstanding curative effect.
In sum, the present invention has following effect:
1. dispel halitosis, especially the stink of Nicotiana tabacum L.; And keep oral cavity fresh and cool, nice and cool and delicate fragrance;
2. eliminate the living radical that sucks in the intravital smoke from cigarette rapidly, protection oral cavity, respiratory tract
Epithelial cell;
3. increase the immunocompetence in pulmonary, throat and oral cavity, repair the lung that damages by smoking, trachea,
Stomatocyte prevents or reduces the cancered probability of gene mutation;
4. control the smoking trachea, oral cavity, pharyngolaryngitis and the detoxifcation that cause are eliminated the phlegm;
5. protect and repair the tracheobronchial cilium that smoking damages, so that discharge medicated cigarette particle etc.
Poisonous carcinogen;
6. protection alveolar and terminal bronchus reduce the disease that smokings such as suffering from emphysema, asthma causes;
7. the discharge of radioactive substance and heavy metal in the medicated cigarette of radioprotective and acceleration pulmonary deposition;
8. eliminate the tooth smoking patch and prevent the tooth calculus.
Use that prescription of the present invention can be made spray, the agent of dusting, buccal tablet, chewing gum, confection etc., and oral liquid, electuary, tablet and capsular additive.The agent of wherein spraying, dust is best to the effect of bronchus, trachea and pulmonary; Buccal tablet is best to the effect in throat, oral cavity.Comprehensively best with the effect of spraying.
The following examples can make those skilled in the art more fully understand the present invention, but do not limit the present invention in any way.
Embodiment one
Make refrigerant strong larynx buccal tablet.Natural Folium Menthae extract (Mentholum with 1.2%, Oleum menthae), 15% Folium Camelliae sinensis extract (tea polyphenols, tea catechin, the mixture of theophylline), 4% Semen Ginkgo extrac (flavone and ginkgolide mixture), 2.5% Radix Astragali extract, 1.5% Semen Sterculiae Lychnophorae extract, 10% wolfberry fruit extract, 2% Radix Glycyrrhizae extract, 5% Fructus Hippophae extract, 2% Testa oryzae extract, 0.001% steviosin, remainder adds the pure water mix homogeneously, adds and makes the required conventional adjuvant of buccal tablet, contains the blade technolgy making routinely and gets final product.(above-mentioned percent is to be percetage by weight, and is as follows)
Embodiment two
Make tasty and refreshing mouth-keeping tablet for reliving sore-throat.Natural Folium Menthae extract with 2.5%, 13% Folium Camelliae sinensis extract (composition), 1.5% Radix Glycyrrhizae extract with embodiment one, 5% Semen Ginkgo extrac, 4.5% Radix Astragali extract, 0.5% Testa oryzae extract, 15% wolfberry fruit extract, 5% Semen Sterculiae Lychnophorae extract, 12% Fructus Hippophae extract, 3% chlorophyll, add 2% edible glue, remainder adds the starch mix homogeneously, and tabletting promptly can be made into tasty and refreshing mouth-keeping tablet for reliving sore-throat.
Embodiment three
Make anti-cancer lung heat clearing spray.With 0.8% natural Folium Menthae extract, 12% Folium Camelliae sinensis extract (tea polyphenols that contains purity 95%, the tea catechin of purity 65%, the trace caffeine), 2.5% Radix Glycyrrhizae extract, 0.5% Semen Ginkgo extrac (component is with embodiment one), 10% Radix Astragali extract, 1% Semen Sterculiae Lychnophorae extract, 8% wolfberry fruit extract, 8% Fructus Hippophae extract, 0.5% Testa oryzae extract, remainder is crossed 0.2 μ m film degerming after adding the pure water mixing, and the aseptic aerosol apparatus of packing into gets final product.
Embodiment four
Make anti-cancer moistening and cleaning throat chewing gum additive.With 0.5% natural Folium Menthae extract, 10% Folium Camelliae sinensis extract (component is with embodiment one), 1.2% Radix Glycyrrhizae extract, 2% Semen Sterculiae Lychnophorae extract, 20% wolfberry fruit extract, 1% Testa oryzae extract, 5% Radix Astragali extract, 2% Fructus Hippophae extract, all the other add the water mix homogeneously, as the additive of chewing gum.
Embodiment five
Make the cigarette companion spray.With 0.2% natural Folium Menthae extract, 25% Folium Camelliae sinensis extract (component is with embodiment three), 2% Radix Glycyrrhizae extract, 0.1% Testa oryzae extract, 0.5% Semen Sterculiae Lychnophorae extract, 20% wolfberry fruit extract, 5% Semen Ginkgo extrac, 5% Fructus Hippophae extract, 2% Radix Astragali extract, remainder adds the water mixing, makes the spraying powder after the spray drying.
Embodiment six
Make refrigerant strong lung spray.With 0.1% Folium Menthae extract, 20% Folium Camelliae sinensis extract, 8% Radix Glycyrrhizae extract, 12% wolfberry fruit extract, 5% Semen Sterculiae Lychnophorae extract, 1% Radix Astragali extract, 3% Fructus Hippophae extract, all the other add 20% ethanol water, aseptic filtration, the aerosol apparatus of packing into gets final product.
Embodiment seven
Make smoker's Bao oral liquid.25% Folium Camelliae sinensis is removed the theophylline extract, 1% Radix Glycyrrhizae extract, 5% wolfberry fruit extract, 10% Fructus Hippophae extract, 3% Radix Astragali extract, 0.5% Semen Sterculiae Lychnophorae extract, 5% Semen Ginkgo extrac, 0.01% steviosin, all the other are conventional oral liquid adjuvants, flash-sterilization, and bottling gets final product.
Embodiment eight
Make damage by fume dissolved granule clearly.5% Folium Camelliae sinensis is removed the theophylline extract, 0.3% Radix Glycyrrhizae extract, 6% wolfberry fruit extract, 10% Fructus Hippophae extract, 4% Radix Astragali extract, 0.5% Semen Sterculiae Lychnophorae extract, 0.02% steviosin, 35% dissolved granule is used adjuvant always, all the other are water, behind the mix homogeneously, the technology of dissolved granule is made routinely, gets final product.
Embodiment nine
Make throat clearing and moistening sugar.With 1% Folium Menthae extract, 7% Folium Camelliae sinensis extract, 2% Radix Glycyrrhizae extract, 10% wolfberry fruit extract, 8% Fructus Hippophae extract, 2% Radix Astragali extract, 1% Semen Sterculiae Lychnophorae extract, all the other add entry, and the remaining common process of pressing confection is made, and gets final product.
Embodiment ten
Make and remove the damage by fume capsule.Folium Camelliae sinensis extract with 25%, 1% Radix Glycyrrhizae extract, 25% wolfberry fruit extract, 15% Fructus Hippophae extract, 5% Radix Astragali extract, 1% Semen Sterculiae Lychnophorae extract, all the other add entry, behind the mix homogeneously, the microwave instantaneously sterilising after the spray drying, incapsulates, and gets final product.
Although the present invention has been done detailed explanation and some instantiations is provided, to those skilled in the art, only otherwise leave that the spirit and scope of the present invention can be done various variations or correction is obvious.
Claims (6)
1. a pure natural health-care article for eliminating smoke harm is characterized in that it comprises following plants: the extract of Folium Camelliae sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Semen Sterculiae Lychnophorae and Fructus Hippophae; The content of each component is respectively: 0.2-50% Folium Camelliae sinensis extract or Folium Camelliae sinensis remove the theophylline extract, and main active princlple is tea polyphenols, tea catechin and theophylline or removes the tea polyphenols of theophylline, the mixture of tea catechin; The 0.1-20% Radix Glycyrrhizae extract, main active princlple is Angelica Polysaccharide and glycyrrhizin; The 0.1-30% wolfberry fruit extract, main active princlple is a lycium barbarum polysaccharide; The 0.1-20% Radix Astragali extract, main active princlple is astragalus polysaccharides and astragaloside; The 0.3-5% Semen Sterculiae Lychnophorae extract, main active princlple is the Semen Sterculiae Lychnophorae polysaccharide; The 0.1-15% Fructus Hippophae extract, main effective ingredient is the Oleum Hippophae that contains unsaturated aldehyde, unsaturated fatty acid, Ai Miliu lipidol class, vitamin C, vitamin E, beta-carotene, surplus is a pharmaceutical adjunct, all percents are percetage by weight, and wherein said Folium Camelliae sinensis, Radix Glycyrrhizae, Fructus Lycii, the Radix Astragali, Semen Sterculiae Lychnophorae and Fructus Hippophae extract are to adopt CO 2 supercritical or the extractive method of pure water to extract.
2. health product according to claim 1, it is characterized in that optionally adding in addition Folium Menthae extract, Semen Ginkgo extrac and/or Testa oryzae extract, wherein Semen Ginkgo extrac, Testa oryzae extract are to take the method for CO 2 supercritical or pure water extracting and chromatography to extract, and the Semen Ginkgo extrac Main Ingredients and Appearance is ginkgetin and ginkgolide; The Folium Menthae extract Main Ingredients and Appearance is Mentholum and Oleum menthae; Testa oryzae extract Main Ingredients and Appearance is rice bran polysaccharide (RBP) and lipids.
3. health product according to claim 2 is characterized in that the each component content that is added is: 0.1-5% Folium Menthae extract, 0.2-25% Semen Ginkgo extrac; 0.1-5% Testa oryzae extract; All percents are percetage by weight.
4. according to each described health product of claim 1 to 3, it is characterized in that being added with in addition the steviosin of 0.0001-0.01%.
5. according to each described health product of claim 1 to 3, it is characterized in that described health product are to make buccal tablet, confection, chewing gum, spray or aerosol, oral liquid, tablet or capsule formulation.
6. health product according to claim 4 is characterized in that described health product are to make buccal tablet, confection, chewing gum, spray or aerosol, oral liquid, tablet or capsule formulation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99108070 CN1076616C (en) | 1999-06-07 | 1999-06-07 | Pure natural health-care article for eliminating smoke harm |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99108070 CN1076616C (en) | 1999-06-07 | 1999-06-07 | Pure natural health-care article for eliminating smoke harm |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1242999A CN1242999A (en) | 2000-02-02 |
| CN1076616C true CN1076616C (en) | 2001-12-26 |
Family
ID=5273118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 99108070 Expired - Fee Related CN1076616C (en) | 1999-06-07 | 1999-06-07 | Pure natural health-care article for eliminating smoke harm |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1076616C (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002063982A1 (en) * | 2001-02-09 | 2002-08-22 | New Chapter, Inc. | Composition and method for smoke detoxification |
| US20080166307A1 (en) * | 2007-01-10 | 2008-07-10 | Jose Eder Fontana | Oral Care Compositions Comprising a Hippophae Extract |
| CN101926430B (en) * | 2010-08-06 | 2013-01-23 | 陈森全 | Polyphenol buccal tablets and preparation method thereof |
| CN103301309B (en) * | 2013-07-02 | 2014-09-17 | 赖育标 | Traditional Chinese herbal medicine for treating laryngocarcinoma and esophagus cancer |
| CN106561899A (en) * | 2016-10-24 | 2017-04-19 | 湖北省农业科学院果树茶叶研究所 | Tea buccal tablet capable of protecting liver, and preparation method thereof |
| CN107149028A (en) * | 2017-04-17 | 2017-09-12 | 廖华勇 | Include the gum of micro tobacco flavor |
-
1999
- 1999-06-07 CN CN 99108070 patent/CN1076616C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1242999A (en) | 2000-02-02 |
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