CN107582796A - A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx and preparation method thereof - Google Patents

A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx and preparation method thereof Download PDF

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CN107582796A
CN107582796A CN201710860984.4A CN201710860984A CN107582796A CN 107582796 A CN107582796 A CN 107582796A CN 201710860984 A CN201710860984 A CN 201710860984A CN 107582796 A CN107582796 A CN 107582796A
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chinese medicine
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王进
鲁宝东
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Anhui Yatai Pharmaceutical Co Ltd
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Anhui Yatai Pharmaceutical Co Ltd
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Abstract

The invention discloses a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx, include the raw material of following parts by weight:68 parts of lactose, 10 14 parts of sugar refinery, 48 parts of maltodextrin, 24 parts of honey, 57 parts of nourishing additive agent, 59 parts of hydroxypropyl cellulose, 12 parts of magnesium stearate, 15 20 parts of filler, wet and slippery dose 68 parts, 48 parts of fruit juice, 12 parts of Folium Forsythiae extract, 0.5 1 parts of flower mixed extract, 46 parts of phoenix-tail fern, 24 parts of dried orange peel, 46 parts of Chinese yam, 24 parts of Radix Angelicae Sinensis, 57 parts of Poria cocos, 46 parts of iron holly bark, 35 parts of American Ginseng, 24 parts of peppermint, 35 parts of radix glycyrrhizae, 24 parts of radix scutellariae.The present invention has reducing phlegm and fever, the effect of facilitaing lung cough-relieving, there is significant curative effect for abscess of throat, the pathogenic bacteria in oral cavity can be killed, fresh breath, suppress halitosis, the multiple nutritional components added in addition so that product of the present invention has certain health value, it is useful and harmless to human body, have no side effect.

Description

A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx and preparation method thereof
Technical field
The present invention relates to food processing technology field, and in particular to a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx and its system Preparation Method.
Background technology
Sore-throat is a kind of most common illness, and it is mainly in the cold season in 1 year, flu, tonsillitis, nasal sinus Inflammation, pertussis, sphagitis and virus infection are generally all with sore-throat.Most acute sore throat pains can be within a couple of days to several weeks certainly It is dynamic to disappear;However, if pain lasts exist or aggravated in several days, need to see the doctor.Because if do not controlled for a long time Treat, the disease may cause rheumatic fever, endanger heart and kidney.Any material for stimulating throat and oral mucosa may all cause pharynx Laryngalgia, including virus, bacterium infection, allergic reaction, dust, cigarette, waste gas, hot beverage or food, tooth or gingival infection have When can also involve throat, chronic cough, bone-dry environment, regurgitation of gastric juice and sound of speaking is excessive can equally stimulate throat, sound Hoarse sound is common side effect.As industrialization, urbanization process are accelerated, various waste gas, the continuous row of dust in air Put, air pollution is more serious.Although the environmental consciousness of people gradually strengthens, municipal pollution problem remains serious. Under this overall situation, it is a kind of very common upper respiratory infection that the incidence of disease of oral cavity and pharyngolaryngitis, which also gradually increases pharyngolaryngitis, Disease, among the medication of clinical treatment pharyngolaryngitis, antibiotics is widely used at present, this kind of medicine is although quick, But antibiosis extract for treating can only suppress or kill pharyngeal bacterium, it is impossible to eliminate former lesion, and side effect is also larger.
Secondly the Crack cause of halitosis is mainly due to eating and drinking without temperance, or eats spicy food too much, and overstrain mistake The splenic function exhaustion caused by bad life style such as degree, gastrointestinal function weaken, and food is normally digested in the intestine, Abundance of food waste matter can not excrete, and more product the more, forms toxin and enters intestinal wall blood, trigger various diseases so as to injure internal organs Disease.And depositing the length of food waste matter time one in the intestine will stagnate heat, foul smell is produced, upwards evaporation, pass through oral cavity and nose Pharyngeal position forms halitosis.Carious tooth, gingivitis, periodontitis and diseases of oral mucosa etc. can cause saprophytic bacteria fermentation production in oral cavity Raw stink forms halitosis.Secondly, oral cavity adjacent to infection of the upper respiratory tract disease for example suppurative tonsillitis, chronic maxillary sinusitis, Atrophic rhinitis etc., purulent secretion can be produced and stinked.
At present, at the same treat halitosis and pharyngitis Chinese and Western medicine it is various in style, big multi-component complex, preparation technology difficulty is big, Although all having the effect of certain, therapeutic effect is not thorough, is also easy to recur after healing, and therapeutic domain is narrow, during medication Between it is long, it is impossible to reach the purpose treated both principal and secondary aspect of disease.
The content of the invention
The defects of for prior art, should it is an object of the invention to provide a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx The pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx has reducing phlegm and fever, the effect of facilitaing lung cough-relieving, has significant curative effect for abscess of throat, The pathogenic bacteria in oral cavity can be killed, fresh breath, suppress halitosis, the multiple nutritional components added in addition so that present invention production Product have certain health value, useful and harmless to human body, have no side effect, and raw material is easy to get, and cost is relatively low, and technique is concise, tool There are higher practical value and good application prospect.
The present invention solves technical problem and adopted the following technical scheme that:
The invention provides a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx, include the raw material of following parts by weight:
Lactose 6-8 parts, sugar refinery 10-14 parts, maltodextrin 4-8 parts, honey 2-4 parts, nourishing additive agent 5-7 parts, hydroxy propyl cellulose Plain 5-9 parts, magnesium stearate 1-2 parts, filler 15-20 parts, wet and slippery dose of 6-8 part, fruit juice 4-8 parts, Folium Forsythiae extract 1-2 Part, flower mixed extract 0.5-1 parts, phoenix-tail fern 4-6 parts, dried orange peel 2-4 parts, Chinese yam 4-6 parts, Radix Angelicae Sinensis 2-4 parts, Poria cocos 5-7 parts, Iron holly bark 4-6 parts, American Ginseng 3-5 parts, peppermint 2-4 parts, radix glycyrrhizae 3-5 parts, radix scutellariae 2-4 parts.
Preferably, the pure and fresh cough relief traditional Chinese medicine lozenge of the diminishing inflammation and clearing pharynx includes the raw material of following parts by weight:
7 parts of lactose, 12 parts of sugar refinery, 6 parts of maltodextrin, 3 parts of honey, 6 parts of nourishing additive agent, 7 parts of hydroxypropyl cellulose, stearic acid 1.5 parts of magnesium, 17 parts of filler, wet and slippery dose 7 parts, 1.5 parts of Folium Forsythiae extract, 6 parts of fruit juice, flower mixed extract 0.8 Part, 5 parts of phoenix-tail fern, 3 parts of dried orange peel, 5 parts of Chinese yam, 3 parts of Radix Angelicae Sinensis, 6 parts of Poria cocos, 5 parts of iron holly bark, 4 parts of American Ginseng, 3 parts of peppermint, radix glycyrrhizae 4 parts, 3 parts of radix scutellariae.
Preferably, the preparation method of the sugar refinery is:By granulated sugar and water according to weight ratio 2:1 is added in pot, and heating is dissolved, Boil, temper to liquid glucose in golden yellow to spend, obtain sugar refinery.
Preferably, the nourishing additive agent is wheat germ powder, fish skin powder, semen armeniacae amarae powder according to 3:3:The mixing of 2 compositions Thing.
Preferably, the filler be starch, flour, ground rice according to weight than 4:2:The mixture of 1 composition.
Preferably, described wet and slippery dose be stearate, polyethylene glycol and mannitol according to weight ratio 2:1:The mixing of 3 compositions Thing;
The preparation method of the fruit juice is:According to weight than 3:1:2 pyrus nivalis, pawpaw, apple are added water to cook it is secondary, first Secondary amount of water is the 15% of fruit gross mass, decocts 2-3 hours, is filtrated to get decocting liquid A;Second of amount of water is fruit quality 55%, decoct 1-2 hours, be filtrated to get decocting liquid B, collecting decoction A and decocting liquid B, fruit juice is arrived in low temperature concentration.
Preferably, the preparation method of the Folium Forsythiae extract is:Folium Forsythia be crushed into 50 mesh sieves, load extractor; It is 30 DEG C in temperature, under the conditions of pressure is 18MPa, makes CO2It is Nebulized that gas from gas is changed into liquid, adds weight percent afterwards Specific concentration be 3% ethanol, 2 hours retention times;Then material inflow separator is separated, by the dregs of a decoction and extract Separation;Isolated mixed extract is adsorbed, adsorption time is 4 hours, and Folium Forsythiae extract is obtained after absorption.
Preferably, the preparation method of the flower mixed extract is:According to weight than 2:2:1 by honeysuckle, chrysanthemum, osmanthus Flower thick stick is cleaned, chopping, and the water for being put into 3-5 times of its quality of addition in container is put into ultrasonic extraction instrument, extracts 8-10 minutes, mistake Flower mixed extract is arrived in filter, concentration.
The present invention also provides a kind of preparation method of the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx, comprises the following steps:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, immersion 20-30 minutes in container are poured into, add water as 6-8 times of medicine gross weight, be cooked by slow fire after boiling Boil 1-2 hours, filter, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, 75-85 DEG C is heated to, with speed of agitator 250-350r/ Min stirs 15-17 minutes, is cooled to 65-75 DEG C, addition honey, nourishing additive agent continue to stir 7-9 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir at 40-50 DEG C 20-40 minutes, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 50-60 DEG C, add thick paste C, magnesium stearate prepared by step 4 while stirring, speed of agitator 250-350r/min, 2-3 hours are stirred, obtained mixture are subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine of diminishing inflammation and clearing pharynx that sterilization packaging is invented contains Piece.
Preferably, the preparation process of the pure and fresh cough relief traditional Chinese medicine lozenge of the diminishing inflammation and clearing pharynx is:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, pour into container and soak 25 minutes, add water as 7 times of medicine gross weight, 1.5 are cooked by slow fire after boiling Hour, filtering, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, are heated to 80 DEG C, is stirred with speed of agitator 300r/min 16 minutes, 70 DEG C are cooled to, addition honey, nourishing additive agent continue stirring 8 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir 30 minutes at 45 DEG C, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 55 DEG C, to add thick paste C, magnesium stearate prepared by step 4, speed of agitator 300r/min, stirring 2.5 while stirring Hour, obtained mixture is subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx that sterilization packaging is invented.
Compared with prior art, the present invention has following beneficial effect:
(1)A variety of Chinese herbal medicines are used in a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention, pass through decoction filtering so that Active ingredient is fully extracted so that lozenge plays cough-relieving, resolving sputum, subsides a swelling, and detoxifies, analgesia, and the effect of eliminating the phlegm, cough is treated to people Cough, abscess of throat, laryngalgia, particularly to cough and expectoration, abscess of throat have significant curative effect.
(2)A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention introduces fruit juice and flower mixing extraction Liquid so that the nutritional ingredient of the lozenge of preparation is more rich, rich in vitamin, B family vitamins and vitamin E inorganic salts etc. into Point, can meet the needs of human body is to a variety of essential amino acids, a large amount of electrolytes and minerals simultaneously.
(3)A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention is mainly wheat embryo using nourishing additive agent Powder, fish skin powder, semen armeniacae amarae powder, these materials are high protein, homovitamin E, low-heat, low fat, the nutriment of low cholesterol, are contained There is vitamin B complex, vitamin D, unrighted acid, nucleic acid, folic acid, n-octacosanol and calcium, iron, zinc, selenium etc. more than 10 to plant ore deposit Material etc., it is the supply source of ideal minor metallic element.
(4)A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention has very strong resist using Folium Forsythiae extract Scorching, antibacterial, regulation is immune, removes free radical, oxidation resistant effect.Radix scutellariae can suppress cariogenic bacteria, can effectively reduce bacterium class poison Element, the prevention and treatment available for periodontitis.Umbellate rockjasmine herb or fruit has the effect for the treatment of tonsillitis, sphagitis, stomatitis.Myrobalan couple There is unique curative effect in treatment chronic pharyngitis, abscess of throat, cough due to deficiency of the lung etc..
(5)A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention contains the raw materials such as peppermint, dried orange peel, effective to improve The effect of Traditional Chinese medicine lozenge treatment halitosis so that the Traditional Chinese medicine lozenge of preparation have therapeutic effect is good, it is fast to play a role, it is convenient at any time The advantages of taking everywhere.
(6)A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention has reducing phlegm and fever, the effect of facilitaing lung cough-relieving, right There is significant curative effect in abscess of throat, the pathogenic bacteria in oral cavity can be killed, fresh breath, suppress halitosis, what is added in addition is more Kind nutritional ingredient so that product of the present invention has certain health value, useful and harmless to human body, has no side effect, and raw material is easy , cost is relatively low, and technique is concise, has higher practical value and good application prospect.
Embodiment
With reference to specific embodiment, the technical scheme in the embodiment of the present invention is clearly and completely described, shown So, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Based on the reality in the present invention Example is applied, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, is all belonged to In the scope of protection of the invention.
Embodiment 1.
A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, include the raw material of following parts by weight:
6 parts of lactose, 10 parts of sugar refinery, 4 parts of maltodextrin, 2 parts of honey, 5 parts of nourishing additive agent, 5 parts of hydroxypropyl cellulose, stearic acid 1 part of magnesium, 15 parts of filler, wet and slippery dose 6 parts, 4 parts of fruit juice, 1 part of Folium Forsythiae extract, 0.5 part of flower mixed extract, phoenix Tail grass 4 parts, 2 parts of dried orange peel, 4 parts of Chinese yam, 2 parts of Radix Angelicae Sinensis, 5 parts of Poria cocos, 4 parts of iron holly bark, 3 parts of American Ginseng, 2 parts of peppermint, 3 parts of radix glycyrrhizae, 2 parts of radix scutellariae.
The preparation method of sugar refinery in the present embodiment is:By granulated sugar and water according to weight ratio 2:1 adds in pot, and heating is molten Change, boil, temper to liquid glucose in golden yellow to spend, obtain sugar refinery.
Nourishing additive agent in the present embodiment is wheat germ powder, fish skin powder, semen armeniacae amarae powder are according to 3:3:The mixing of 2 compositions Thing.
Filler in the present embodiment is starch, flour, ground rice according to weight than 4:2:The mixture of 1 composition.
Wet and slippery dose in the present embodiment is stearate, polyethylene glycol and mannitol according to weight ratio 2:1:3 compositions mix Compound;
The preparation method of fruit juice in the present embodiment is:According to weight than 3:1:2 add water to cook pyrus nivalis, pawpaw, apple Secondary, first time amount of water is the 15% of fruit gross mass, decocts 2 hours, is filtrated to get decocting liquid A;Second of amount of water is water The 55% of fruit quality, decoct 1 hour, be filtrated to get decocting liquid B, collecting decoction A and decocting liquid B, fruit juice is arrived in low temperature concentration.
The preparation method of Folium Forsythiae extract in the present embodiment is:Folium Forsythia be crushed into 50 mesh sieves, load extractor; It is 30 DEG C in temperature, under the conditions of pressure is 18MPa, makes CO2It is Nebulized that gas from gas is changed into liquid, adds weight percent afterwards Specific concentration be 3% ethanol, 2 hours retention times;Then material inflow separator is separated, by the dregs of a decoction and extract Separation;Isolated mixed extract is adsorbed, adsorption time is 4 hours, and Folium Forsythiae extract is obtained after absorption.
The preparation method of flower mixed extract in the present embodiment is:According to weight than 2:2:1 by honeysuckle, chrysanthemum, Sweet osmanthus thick stick is cleaned, chopping, and the water for being put into 3-5 times of its quality of addition in container is put into ultrasonic extraction instrument, extracts 8-10 minutes, Flower mixed extract is arrived in filtering, concentration.
A kind of preparation method of the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, comprises the following steps:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, pour into container and soak 20 minutes, add water as 6 times of medicine gross weight, it is small to be cooked by slow fire 1 after boiling When, filtering, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, are heated to 75 DEG C, is stirred with speed of agitator 250r/min 15 minutes, 65 DEG C are cooled to, addition honey, nourishing additive agent continue stirring 7 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir 20 minutes at 40 DEG C, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 50 DEG C, to add thick paste C, magnesium stearate prepared by step 4 while stirring, speed of agitator 250r/min, it is small stirring 2 When, obtained mixture is subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx that sterilization packaging is invented.
Embodiment 2.
A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, include the raw material of following parts by weight:
8 parts of lactose, 14 parts of sugar refinery, 8 parts of maltodextrin, 4 parts of honey, 7 parts of nourishing additive agent, 9 parts of hydroxypropyl cellulose, stearic acid 2 parts of magnesium, 20 parts of filler, wet and slippery dose 8 parts, 8 parts of fruit juice, 2 parts of Folium Forsythiae extract, 1 part of flower mixed extract, phoenix tail 6 parts of grass, 4 parts of dried orange peel, 6 parts of Chinese yam, 4 parts of Radix Angelicae Sinensis, 7 parts of Poria cocos, 6 parts of iron holly bark, 5 parts of American Ginseng, 4 parts of peppermint, 5 parts of radix glycyrrhizae, Huang 4 parts of a kind of reed mentioned in ancient books.
The preparation method of sugar refinery in the present embodiment is:By granulated sugar and water according to weight ratio 2:1 adds in pot, and heating is molten Change, boil, temper to liquid glucose in golden yellow to spend, obtain sugar refinery.
Nourishing additive agent in the present embodiment is wheat germ powder, fish skin powder, semen armeniacae amarae powder are according to 3:3:The mixing of 2 compositions Thing.
Filler in the present embodiment is starch, flour, ground rice according to weight than 4:2:The mixture of 1 composition.
Wet and slippery dose in the present embodiment is stearate, polyethylene glycol and mannitol according to weight ratio 2:1:3 compositions mix Compound;
The preparation method of fruit juice in the present embodiment is:According to weight than 3:1:2 add water to cook pyrus nivalis, pawpaw, apple Secondary, first time amount of water is the 15% of fruit gross mass, decocts 3 hours, is filtrated to get decocting liquid A;Second of amount of water is water The 55% of fruit quality, decoct 2 hours, be filtrated to get decocting liquid B, collecting decoction A and decocting liquid B, fruit juice is arrived in low temperature concentration.
The preparation method of Folium Forsythiae extract in the present embodiment is:Folium Forsythia be crushed into 50 mesh sieves, load extractor; It is 30 DEG C in temperature, under the conditions of pressure is 18MPa, makes CO2It is Nebulized that gas from gas is changed into liquid, adds weight percent afterwards Specific concentration be 3% ethanol, 2 hours retention times;Then material inflow separator is separated, by the dregs of a decoction and extract Separation;Isolated mixed extract is adsorbed, adsorption time is 4 hours, and Folium Forsythiae extract is obtained after absorption.
The preparation method of flower mixed extract in the present embodiment is:According to weight than 2:2:1 by honeysuckle, chrysanthemum, Sweet osmanthus thick stick is cleaned, chopping, and the water for being put into 3-5 times of its quality of addition in container is put into ultrasonic extraction instrument, extracts 8-10 minutes, Flower mixed extract is arrived in filtering, concentration.
A kind of preparation method of the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, comprises the following steps:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, pour into container and soak 30 minutes, add water as 8 times of medicine gross weight, it is small to be cooked by slow fire 2 after boiling When, filtering, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, are heated to 85 DEG C, is stirred with speed of agitator 350r/min 17 minutes, 75 DEG C are cooled to, addition honey, nourishing additive agent continue stirring 9 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir 40 minutes at 50 DEG C, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 60 DEG C, to add thick paste C, magnesium stearate prepared by step 4 while stirring, speed of agitator 350r/min, it is small stirring 3 When, obtained mixture is subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx that sterilization packaging is invented.
Embodiment 3.
A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, include the raw material of following parts by weight:
7 parts of lactose, 12 parts of sugar refinery, 6 parts of maltodextrin, 3 parts of honey, 6 parts of nourishing additive agent, 7 parts of hydroxypropyl cellulose, stearic acid 1.5 parts of magnesium, 17 parts of filler, wet and slippery dose 7 parts, 1.5 parts of Folium Forsythiae extract, 6 parts of fruit juice, flower mixed extract 0.8 Part, 5 parts of phoenix-tail fern, 3 parts of dried orange peel, 5 parts of Chinese yam, 3 parts of Radix Angelicae Sinensis, 6 parts of Poria cocos, 5 parts of iron holly bark, 4 parts of American Ginseng, 3 parts of peppermint, radix glycyrrhizae 4 parts, 3 parts of radix scutellariae.
The preparation method of sugar refinery in the present embodiment is:By granulated sugar and water according to weight ratio 2:1 adds in pot, and heating is molten Change, boil, temper to liquid glucose in golden yellow to spend, obtain sugar refinery.
Nourishing additive agent in the present embodiment is wheat germ powder, fish skin powder, semen armeniacae amarae powder are according to 3:3:The mixing of 2 compositions Thing.
Filler in the present embodiment is starch, flour, ground rice according to weight than 4:2:The mixture of 1 composition.
Wet and slippery dose in the present embodiment is stearate, polyethylene glycol and mannitol according to weight ratio 2:1:3 compositions mix Compound;
The preparation method of fruit juice in the present embodiment is:According to weight than 3:1:2 add water to cook pyrus nivalis, pawpaw, apple Secondary, first time amount of water is the 15% of fruit gross mass, decocts 2.5 hours, is filtrated to get decocting liquid A;Second of amount of water be The 55% of fruit quality, decoct 1.5 hours, be filtrated to get decocting liquid B, collecting decoction A and decocting liquid B, fruit is arrived in low temperature concentration Juice.
The preparation method of Folium Forsythiae extract in the present embodiment is:Folium Forsythia be crushed into 50 mesh sieves, load extractor; It is 30 DEG C in temperature, under the conditions of pressure is 18MPa, makes CO2It is Nebulized that gas from gas is changed into liquid, adds weight percent afterwards Specific concentration be 3% ethanol, 2 hours retention times;Then material inflow separator is separated, by the dregs of a decoction and extract Separation;Isolated mixed extract is adsorbed, adsorption time is 4 hours, and Folium Forsythiae extract is obtained after absorption.
The preparation method of flower mixed extract in the present embodiment is:According to weight than 2:2:1 by honeysuckle, chrysanthemum, Sweet osmanthus thick stick is cleaned, chopping, and the water for being put into 4 times of its quality of addition in container is put into ultrasonic extraction instrument, is extracted 9 minutes, filtering, Flower mixed extract is arrived in concentration.
A kind of preparation method of the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present embodiment, comprises the following steps:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, pour into container and soak 25 minutes, add water as 7 times of medicine gross weight, 1.5 are cooked by slow fire after boiling Hour, filtering, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, are heated to 80 DEG C, is stirred with speed of agitator 300r/min 16 minutes, 70 DEG C are cooled to, addition honey, nourishing additive agent continue stirring 8 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir 30 minutes at 45 DEG C, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 55 DEG C, to add thick paste C, magnesium stearate prepared by step 4, speed of agitator 300r/min, stirring 2.5 while stirring Hour, obtained mixture is subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx that sterilization packaging is invented.
A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx of the present invention has reducing phlegm and fever, the effect of facilitaing lung cough-relieving, for Abscess of throat has significant curative effect, can kill the pathogenic bacteria in oral cavity, fresh breath, suppress halitosis, what is added in addition is a variety of Nutritional ingredient so that product of the present invention has certain health value, useful and harmless to human body, has no side effect, and raw material is easy to get, Cost is relatively low, and technique is concise, has higher practical value and good application prospect.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie In the case of without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power Profit requires rather than described above limits, it is intended that all in the implication and scope of the equivalency of claim by falling Change is included in the present invention.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (10)

1. a kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx, it is characterised in that include the raw material of following parts by weight:
Lactose 6-8 parts, sugar refinery 10-14 parts, maltodextrin 4-8 parts, honey 2-4 parts, nourishing additive agent 5-7 parts, hydroxy propyl cellulose Plain 5-9 parts, magnesium stearate 1-2 parts, filler 15-20 parts, wet and slippery dose of 6-8 part, fruit juice 4-8 parts, Folium Forsythiae extract 1-2 Part, flower mixed extract 0.5-1 parts, phoenix-tail fern 4-6 parts, dried orange peel 2-4 parts, Chinese yam 4-6 parts, Radix Angelicae Sinensis 2-4 parts, Poria cocos 5-7 parts, Iron holly bark 4-6 parts, American Ginseng 3-5 parts, peppermint 2-4 parts, radix glycyrrhizae 3-5 parts, radix scutellariae 2-4 parts.
A kind of 2. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1, it is characterised in that the diminishing inflammation and clearing pharynx Pure and fresh cough relief traditional Chinese medicine lozenge includes the raw material of following parts by weight:
7 parts of lactose, 12 parts of sugar refinery, 6 parts of maltodextrin, 3 parts of honey, 6 parts of nourishing additive agent, 7 parts of hydroxypropyl cellulose, stearic acid 1.5 parts of magnesium, 17 parts of filler, wet and slippery dose 7 parts, 1.5 parts of Folium Forsythiae extract, 6 parts of fruit juice, flower mixed extract 0.8 Part, 5 parts of phoenix-tail fern, 3 parts of dried orange peel, 5 parts of Chinese yam, 3 parts of Radix Angelicae Sinensis, 6 parts of Poria cocos, 5 parts of iron holly bark, 4 parts of American Ginseng, 3 parts of peppermint, radix glycyrrhizae 4 parts, 3 parts of radix scutellariae.
A kind of 3. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that the sugar refinery Preparation method be:By granulated sugar and water according to weight ratio 2:1 is added in pot, and heating is dissolved, and is boiled, and is tempered to liquid glucose in golden yellow For degree, sugar refinery is obtained.
A kind of 4. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that the nutrition Additive is wheat germ powder, fish skin powder, semen armeniacae amarae powder according to 3:3:The mixture of 2 compositions.
A kind of 5. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that the filling Agent be starch, flour, ground rice according to weight than 4:2:The mixture of 1 composition.
6. the pure and fresh cough relief traditional Chinese medicine lozenge of a kind of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that described wet and slippery Agent is stearate, polyethylene glycol and mannitol according to weight ratio 2:1:The mixture of 3 compositions;
The preparation method of the fruit juice is:According to weight than 3:1:2 pyrus nivalis, pawpaw, apple are added water to cook it is secondary, first Secondary amount of water is the 15% of fruit gross mass, decocts 2-3 hours, is filtrated to get decocting liquid A;Second of amount of water is fruit quality 55%, decoct 1-2 hours, be filtrated to get decocting liquid B, collecting decoction A and decocting liquid B, fruit juice is arrived in low temperature concentration.
A kind of 7. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that the capsule of weeping forsythia The preparation method of leaf extract is:Folium Forsythia be crushed into 50 mesh sieves, load extractor;It is 30 DEG C in temperature, pressure 18MPa Under the conditions of, make CO2Gas is changed into the ethanol that liquid is Nebulized, and rear addition weight percent concentration is 3%, retention time from gas 2 hours;Then material inflow separator is separated, the dregs of a decoction and extract is separated;By isolated mixed extract Adsorbed, adsorption time is 4 hours, and Folium Forsythiae extract is obtained after absorption.
A kind of 8. pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 1 or 2, it is characterised in that the flower The preparation method of mixed extract is:According to weight than 2:2:1 by honeysuckle, chrysanthemum, sweet osmanthus thick stick is clean, shreds, and is put into container The interior water for adding 3-5 times of its quality is put into ultrasonic extraction instrument, extracts 8-10 minutes, filtering, and concentration carries to flower mixing Take liquid.
A kind of 9. method for preparing the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx as claimed in claim 1 or 2, it is characterised in that Comprise the following steps:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, immersion 20-30 minutes in container are poured into, add water as 6-8 times of medicine gross weight, be cooked by slow fire after boiling Boil 1-2 hours, filter, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, 75-85 DEG C is heated to, with speed of agitator 250-350r/ Min stirs 15-17 minutes, is cooled to 65-75 DEG C, addition honey, nourishing additive agent continue to stir 7-9 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir at 40-50 DEG C 20-40 minutes, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 50-60 DEG C, add thick paste C, magnesium stearate prepared by step 4 while stirring, speed of agitator 250-350r/min, 2-3 hours are stirred, obtained mixture are subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine of diminishing inflammation and clearing pharynx that sterilization packaging is invented contains Piece.
A kind of 10. preparation method of the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx according to claim 9, it is characterised in that The step is:
Step 1, weigh prepare each component raw material on request;
Step 2, phoenix-tail fern, dried orange peel, Chinese yam and angelica, Poria cocos, iron holly bark, American Ginseng, peppermint, radix glycyrrhizae, radix scutellariae are added and crushed Co-grinding in machine, pour into container and soak 25 minutes, add water as 7 times of medicine gross weight, 1.5 are cooked by slow fire after boiling Hour, filtering, obtain filtrate A;
Step 3, lactose, sugar refinery, maltodextrin are added in reactor, are heated to 80 DEG C, is stirred with speed of agitator 300r/min 16 minutes, 70 DEG C are cooled to, addition honey, nourishing additive agent continue stirring 8 minutes, obtain mixture B;
Step 4, fruit juice, forsythia suspense extraction, flower mixture extract solution, filler are added in homogenizer, in temperature Spend to stir 30 minutes at 45 DEG C, then filtrate is condensed into the thick paste C that relative density at 55 DEG C is 1.2;
Step 5:The mixture B of step 3 preparation, hydroxypropyl cellulose, wet and slippery dose of mixing are added in homogenizer, in temperature Spend at 55 DEG C, to add thick paste C, magnesium stearate prepared by step 4, speed of agitator 300r/min, stirring 2.5 while stirring Hour, obtained mixture is subjected to tabletting, the pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx that sterilization packaging is invented.
CN201710860984.4A 2017-09-21 2017-09-21 A kind of pure and fresh cough relief traditional Chinese medicine lozenge of diminishing inflammation and clearing pharynx and preparation method thereof Pending CN107582796A (en)

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Publication number Priority date Publication date Assignee Title
CN109512740A (en) * 2018-12-20 2019-03-26 扬州倍加洁日化有限公司 Oral cavity composition and its application containing licorice and Cortex Ilicis Rotundae extract
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Application publication date: 20180116