CN115216475A - 用于调节基因表达的寡核苷酸及其用途 - Google Patents
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| PCT/IB2013/051410 WO2013124807A2 (en) | 2012-02-24 | 2013-02-21 | Oligonucleotides for modulating gene expression and uses thereof |
| CN201380009360.1A CN104169421A (zh) | 2012-02-24 | 2013-02-21 | 用于调节基因表达的寡核苷酸及其用途 |
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| JP2015518712A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | Ｍｅｃｐ２発現を調節するための組成物及び方法 |
| JP2015518713A (ja) | 2012-05-16 | 2015-07-06 | ラナ セラピューティクス インコーポレイテッド | Ｕｔｒｎ発現を調節するための組成物及び方法 |
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| CN104583401A (zh) | 2012-05-16 | 2015-04-29 | Rana医疗有限公司 | 用于调节atp2a2表达的组合物和方法 |
| EP2850188A4 (en) | 2012-05-16 | 2016-01-20 | Rana Therapeutics Inc | COMPOSITIONS AND METHOD FOR MODULATING THE EXPRESSION OF THE HEMOGLOBIN GENE FAMILIES |
| WO2013173638A1 (en) | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating smn gene family expression |
| CA3047076A1 (en) * | 2016-12-13 | 2018-06-21 | Am Sciences Inc | Pharmaceutical composition for preventing or treating hepatitis b |
| US20250205341A1 (en) * | 2022-03-22 | 2025-06-26 | Bion Inc. | Protein delivery composition containing bile salt and cationic peptide and use thereof |
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| US20030096739A1 (en) * | 2001-04-13 | 2003-05-22 | Morris Patricia L. | Nuclear receptor-mediated introduction of a PNA into cell nuclei |
| WO2003070917A2 (en) * | 2002-02-20 | 2003-08-28 | Sirna Therapeutics, Inc. | Rna interference mediated inhibition of myc and myb genes or genes of their respective pathways |
| US20060074041A1 (en) * | 1997-08-20 | 2006-04-06 | Somagenics, Inc. | Antisense and antigene therapeutics with improved binding properties and methods for their use |
| US20090324587A1 (en) * | 2005-12-01 | 2009-12-31 | Neal Clifford Goodwin | Cancer Therapies and Pharmaceutical Compositions Used Therein |
| US20110105422A1 (en) * | 2008-02-05 | 2011-05-05 | Gary Acton | Use of g-rich oligonucleotides for treating neoplastic diseases |
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| AU2001235019A1 (en) | 2000-02-14 | 2001-08-27 | Arthur P Bollon | Libraries of optimum subsequence regions of mRNA and genomic DNA for control of gene expression |
| CA2447052A1 (en) * | 2001-05-17 | 2002-11-21 | Avi Biopharma, Inc. | Combined approach to treatment of cancer using a c-myc antisense oligomer |
| ITMI20030860A1 (it) * | 2003-04-29 | 2004-10-30 | Univ Bologna | Metodo per l'inibizione selettiva del gene n-myc |
| WO2005045032A2 (en) * | 2003-10-20 | 2005-05-19 | Sima Therapeutics, Inc. | RNA INTERFERENCE MEDIATED INHIBITION OF EARLY GROWTH RESPONSE GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| GB0415263D0 (en) * | 2004-07-07 | 2004-08-11 | Norwegian Radium Hospital Res | Method |
| MX2007004968A (es) * | 2004-10-25 | 2007-06-15 | Novartis Ag | Polinucleotidos y polipeptidos torc, y metodos de uso. |
| US7625874B2 (en) * | 2006-04-11 | 2009-12-01 | The Regents Of The University Of California | Compositions and methods for treating diseases associated with T-box and N-Myc |
| US20080038783A1 (en) * | 2006-06-29 | 2008-02-14 | Applera Corporation | Compositions and Methods Pertaining to Guanylation of PNA Oligomers |
| US20090047295A1 (en) * | 2007-07-12 | 2009-02-19 | Berry David A | Methods and Compositions for Reducing Stemness in Oncogenesis |
| EP2370582B1 (en) * | 2008-12-04 | 2017-05-10 | CuRNA, Inc. | Treatment of tumor suppressor gene related diseases by inhibition of natural antisense transcript to the gene |
| CN102058535B (zh) * | 2010-12-21 | 2013-05-01 | 中国人民解放军总医院 | 叶酸受体靶向的新型脂质体 |
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