CN1150936C

CN1150936C - Soft-extract for treating hepatitis B and preparation process thereof

Info

Publication number: CN1150936C
Application number: CNB021159289A
Authority: CN
Inventors: 孟昭强; 丁亚萍
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-06-04
Filing date: 2002-06-04
Publication date: 2004-05-26
Anticipated expiration: 2022-06-04
Also published as: CN1385205A

Abstract

The present invention belongs to a pure Chinese medicinal preparation for treating acute and chronic hepatitis B and a preparation technology. Dry Chinese medicine materials comprising phyllanthus, artemisiae scopariae, schisandra fruit, pseudostellaria root, japanese ardisia, hawthorn, glossy privet fruit, smilacis glabrae, etc. are prepared into hepatitis B honey paste. The preparation has strong functions of protecting the liver and resisting hepatic fibrosis and hepatitis B viruses. The preparation can be used for treating hepatitis B, and has the advantages of good curative effect, no toxic or side effect, convenient taking, rich medicinal sources, simple preparation and low cost.

Description

A kind of sweet cream for the treatment of hepatitis B

Affiliated technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of hepatitis B and preparation method thereof.

Background technology

The hepatitis B patient is more, morbidity is slow, progress is slow, recover slow, and the medicine that is used for the acute hepatitis B (AHB) and light, medium-sized chronic viral hepatitis B (CHB) state of an illness clinically is more, and most of medicine has side effect and medicine valency expensive, be difficult for being accepted by extensive patients, the preparation that has is more complicated then.

Summary of the invention

In order to overcome the existing deficiency of controlling hepatitis B medicine, the invention provides that a kind of making is taken simply, curative effect is higher, former treatment hepatitis B extensive, the with low cost honey of medicine cream.

The technical scheme that the present invention takes is: a kind of sweet cream for the treatment of hepatitis B is characterized in that being being made by the crude drug of following weight:

Herba Phyllanthi Urinariae 10-30g Herba Artemisiae Scopariae 10-40g Fructus Schisandrae Chinensis 10-30g Radix Pseudostellariae 10-25g

Herba Ardisiae Japonicae 10-30g Fructus Crataegi 10-30g Fructus Ligustri Lucidi 10-30g Rhizoma Imperatae 10-25g

Rhizoma Smilacis Glabrae 10-30g Radix Et Rhizoma Rhei 10-30g Radix Bupleuri 5-15g Radix Angelicae Sinensis 5-25g

Semen Phaseoli 10-30g Radix Salviae Miltiorrhizae 10-30g Rhizoma Polygoni Cuspidati 5-20g Fructus Phyllanthi 5-25g

Radix Isatidis 10-30g Radix Scutellariae 10-30g.

Above-mentioned prescription medicine is followed the prescribed rules by the pharmacopeia regulation, is made into soft-extract for treating hepatitis B as follows.

Crude drug in the prescription is cleaned, the water logging of heating bubble 1 hour, decoct and carry out the extracting juice first time after 2 hours, medicinal residues add water again and carry out the extracting juice second time after 1 hour with slow fire boiling behind the extracting juice, with twice medicine juice hybrid filtering, precipitate 24 hours, it is stand-by to get supernatant, this stand-by liquid is added Mel 1000 grams again and concentrate, cryoconcentration becomes sweet cream, packaging sterilizing in fast one-tenth cream.

The present invention is on the basis of following the traditional Chinese medical science principles of formulating prescriptions, applied in a flexible way again monarch, minister, help, make the principle of concerted application of drugs, selected first-class Chinese crude drug is used as medicine, according to hepatitis B pathogenesis basis and clinical manifestation, acute hepatitis is many because of damp-heat in the spleen and stomach, select Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Rhizoma Imperatae etc. in the event side for use, also used some heat-clearing and diuresis-promoting drugs such as Radix Scutellariae, Radix Isatidis.The main disease type of chronic hepatitis has stagnation of liver-QI with deficiency of the spleen, qi depression to blood stasis, the hepatic and renal YIN deficiency etc., Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi etc. are arranged in the side, and it all is that the hepatitis B patient can't obtain from other drug that used Mel contains abundant glucose, protein, vitamin, trace element or the like.

The invention has the beneficial effects as follows, year surplus being used for clinical ten, to anxious slow hepatitis B patient determined curative effect, the abnormal liver function person is taken soft-extract for treating hepatitis B, and to make 90% patient recover liver function in 1 month normal, have 42% to turn out cloudy to HBV-DNA positive person, special case by the tracing study of clothes soft-extract for treating hepatitis B, is not found to suffer from hepatitis interstitialis chronica, so explanation has anti-hepatic fibrosis, hepatoprotective effect.Acute hepatitis B patient liver function, HBV-DNA measured values such as (+) surpass 2.5 times of normal values, double to obey soft-extract for treating hepatitis B, 3-6 month general course of treatment.Technology of preparing of the present invention is simple, need not special installation, and taking convenience.

The specific embodiment:

Restrain (percentage by weight) in following prescription and the selected first-class process of preparing Chinese medicine Chinese crude drug 300 of ratio:

Herba Phyllanthi Urinariae 10.3 Herba Artemisiae Scopariaes 10.3 Fructus Schisandrae Chinensis 5.2 Radix Pseudostellariaes 4.1

Herba Ardisiae Japonicae 6.9 Fructus Crataegis 5.2 Fructus Ligustri Lucidi 5.2 Rhizoma Imperataes 5.2

Rhizoma Smilacis Glabrae 6.9 Radix Et Rhizoma Rhei 4.1 Radix Bupleuri 2.1 Radix Angelicae Sinensis 3.4

Semen Phaseoli 6.9 Radix Salviae Miltiorrhizaes 5.2 Rhizoma Polygoni Cuspidati 3.4 Fructus Phyllanthis 3.4

Radix Isatidis 6.9 Radix Scutellariaes 5.2

Crude drug in the prescription is cleaned, the water logging of heating bubble 1 hour, decoct and carry out the extracting juice first time after 2 hours, medicinal residues add water again and carry out the extracting juice second time after 1 hour with slow fire boiling behind the extracting juice, with twice medicine juice hybrid filtering, precipitate 24 hours, get supernatant and add Mel 1000g and concentrate, in fast one-tenth cream, change cryoconcentration and become sweet cream, packaging sterilizing.

Instructions of taking: adult's secondary every day, each 20 grams, the patient with severe symptoms at each 40 grams of physician guidance following every day of secondary, takes after mixing it with hot water, and children's follows the doctor's advice.

Model case:

Example one, Chen, man, 28 years old, people from Ezhou, look into trouble hepatitis B, HBsAg (+) HBeAg (+), TBIL68umo/L, ALT680/L in April, 2000, HBV-DNA (+), abdominal distention is detested oil, yellow urine, myasthenia of limbs, diet are not good, begin to take soft-extract for treating hepatitis B after 1 month April, liver function recovery is normal, take 2 months again after, HBeAg (-), adhere to clothes after 6 months, HBsAg (±), HBV-DNA (-).

Example two, Zhang, woman, 9 years old, people from Daye City looks into trouble hepatitis B, HBsAg (+) in May, 2000, HBeAg (+), anti-HBc (+), diet is depressed, right rib pain, bitter taste, body of the tongue is light red, the deep-thready pulse string, clothes soft-extract for treating hepatitis B 2 months, transference cure, obeyed soft-extract for treating hepatitis B again 1 month, and looked into HBeAg (-), liver function is normal.

Example three, Liu, the man, the Jiangxia District people looks into trouble hepatitis B, HBsAg (+) in March, 2000, anti-HBe (+), anti-HBc (+), ALT150u/L, asymptomatic, began to obey soft-extract for treating hepatitis B 2 months March, ALT40u/L, the HBsAg titre descends, obeyed again 2 months, HBV-DNA (-), the HBsAg titre continues to descend.

Claims

1, a kind of sweet cream for the treatment of hepatitis B is characterized in that being being made by the crude drug of following weight:

Radix Isatidis 10-30g Radix Scutellariae 10-30g.

2, a kind of sweet cream for the treatment of hepatitis B according to claim 1, it is characterized in that its preparation method is: the crude drug in the prescription is cleaned, the water logging of heating bubble 1 hour decocts and carries out the extracting juice first time after 2 hours, and medicinal residues add water again and carry out the extracting juice second time after 1 hour with slow fire boiling behind the extracting juice, with twice medicine juice hybrid filtering, precipitate 24 hours, it is stand-by to get supernatant, this stand-by liquid is added Mel 1000 grams again and concentrates, in fast one-tenth cream, change cryoconcentration and become sweet cream, packaging sterilizing.