CN1385205A

CN1385205A - Soft-extract for treating hepatitis B and preparation process thereof

Info

Publication number: CN1385205A
Application number: CN 02115928
Authority: CN
Inventors: 孟昭强; 丁亚萍
Original assignee: Individual
Current assignee: Individual
Priority date: 2002-06-04
Filing date: 2002-06-04
Publication date: 2002-12-18
Anticipated expiration: 2022-06-04
Also published as: CN1150936C

Abstract

The present invention belongs to a pure Chinese medicine preparation for curing aucte and chronic hepatitis B and its preparation process. It is made of 8 Chinese medicinal materials of phyllanthus, capillaris, schisandra berry, pseudostellaria root, Japanase ardisia stem and leaf and others. Said medicine preparation is a soft-extract, and possesses the actions of protecting liver, resisting fibrosis of liver and resisting hepatitis B virus, and is high in therapeutic effect and has no toxic side effect.

Description

Soft-extract for treating hepatitis B and preparation method

Affiliated technical field

The present invention relates to a kind of Chinese medicine preparation for the treatment of hepatitis B and preparation method thereof.

Background technology

The hepatitis B patient is more, morbidity is slow, progress is slow, recover slow, and the medicine that is used for the acute hepatitis B (AHB) and light, medium-sized chronic viral hepatitis B (CHB) state of an illness clinically is more, and most of medicine has side effect and medicine valency expensive, be difficult for being accepted by extensive patients, the preparation that has is more complicated then.

Summary of the invention

In order to overcome the existing deficiency of controlling hepatitis B medicine, the invention provides the treatment hepatitis B honey cream that a kind of making is taken simply, curative effect is higher, the medicine source is extensive, with low cost.

The technical scheme that the present invention takes is: a kind of soft-extract for treating hepatitis B is characterized in that its prescription following (weight in grams): Herba Phyllanthi Urinariae 10-30 Herba Artemisiae Scopariae 10-40 Fructus Schisandrae Chinensis 10-30 Radix Pseudostellariae 10-25 Herba Ardisiae Japonicae 10-30 Fructus Crataegi 10-30 Fructus Ligustri Lucidi 10-30 Rhizoma Imperatae 10-30 Rhizoma Smilacis Glabrae 10-30 Radix Et Rhizoma Rhei 10-30 Radix Bupleuri 5-15 Radix Angelicae Sinensis 5-25 Semen Phaseoli 10-30 Radix Salviae Miltiorrhizae 10-30 Rhizoma Polygoni Cuspidati 5-20 Fructus Phyllanthi 5-25 Radix Isatidis 10-30 Radix Scutellariae 10-30

Above-mentioned prescription medicine is followed the prescribed rules by the pharmacopeia regulation, is made into soft-extract for treating hepatitis B as follows.

Getting prescription medicine cleans, the water logging of heating bubble 1 hour, decoct extracting juice after 2 hours (juice for the first time), medicinal residues decoct with water (slow fire) 1 hour extracting juice (juice for the second time) again behind the extracting juice, with twice medicine juice hybrid filtering, precipitate 24 hours, it is stand-by to get supernatant, again this stand-by liquid is added Mel 1000 grams and concentrate, in fast one-tenth cream, change cryoconcentration and become sweet cream, packaging sterilizing.

The present invention is on the basis of following the traditional Chinese medical science principles of formulating prescriptions, applied in a flexible way again monarch, minister, help, make the principle of concerted application of drugs, selected first-class Chinese crude drug is used as medicine, according to hepatitis B pathogenesis basis and clinical manifestation, acute hepatitis is many because of damp-heat in the spleen and stomach, select Herba Artemisiae Scopariae, Radix Et Rhizoma Rhei, Rhizoma Imperatae etc. in the event side for use, also used some heat-clearing and diuresis-promoting drugs such as Radix Scutellariae, Radix Isatidis.The main disease type of chronic hepatitis has stagnation of liver-QI with deficiency of the spleen, qi depression to blood stasis, the hepatic and renal YIN deficiency etc., Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Fructus Ligustri Lucidi etc. are arranged in the side, and it all is that the hepatitis B patient can't obtain from other drug that used Mel contains abundant glucose, protein, vitamin, trace element or the like.

The invention has the beneficial effects as follows, year surplus being used for clinical ten, to anxious slow hepatitis B patient determined curative effect, the abnormal liver function person is taken soft-extract for treating hepatitis B can make 90% in 1 month, it is normal that the patient recovers liver function, has 42% to turn out cloudy to HBV-DNA positive person, and special case is passed through the tracing study of clothes soft-extract for treating hepatitis B, do not find to suffer from hepatitis interstitialis chronica, so explanation has anti-hepatic fibrosis, hepatoprotective effect.Acute hepatitis B patient liver function, HBV-DNA measured values such as (+) surpass 2.5 times of normal values, double to obey soft-extract for treating hepatitis B, 3-6 month general course of treatment.Technology of preparing of the present invention is simple, need not special installation, and taking convenience.

The specific embodiment

Restrain (percentage by weight) in following prescription and the selected first-class process of preparing Chinese medicine Chinese crude drug 300 of ratio: Herba Phyllanthi Urinariae 10.3 Herba Artemisiae Scopariaes 10.3 Fructus Schisandrae Chinensis 5.2 Radix Pseudostellariaes 4.1 Herba Ardisiae Japonicaes 6.9 Fructus Crataegis 5.2 Fructus Ligustri Lucidi 5.2 Rhizoma Imperataes 5.2 Rhizoma Smilacis Glabraes 6.9 Radix Et Rhizoma Rhei 4.1 Radix Bupleuri 2.1 Radix Angelicae Sinensis 3.4 Semen Phaseolis 6.9 Radix Salviae Miltiorrhizaes 5.2 Rhizoma Polygoni Cuspidati 3.4 Fructus Phyllanthis 3.4 Radix Isatidis 6.9 Radix Scutellariaes 5.2

Getting said medicine cleans, the water logging of heating bubble 1 hour, decoct and get medicine juice for the first time after 2 hours, decoct with water (slow fire) again and get medicine juice for the second time after 1 hour, with twice medicine juice hybrid filtering, precipitate 24 hours, get supernatant and add Mel 1000 gram and concentrate, in fast one-tenth cream, change cryoconcentration and become sweet cream, packaging sterilizing.

Instructions of taking: adult's secondary every day, each 20 grams, the patient with severe symptoms at each 40 grams of physician guidance following every day of secondary, takes after mixing it with hot water, and children's follows the doctor's advice.Model case

Example one, Chen, man, 28 years old, people from Ezhou look into trouble hepatitis B, HBsAg (+) HBeAg (+) in April, 2000, TBIL68umol/L, ALT680u/L, HB V-DNA (+), abdominal distention is detested oil, yellow urine, myasthenia of limbs, diet are not good, begin to take soft-extract for treating hepatitis B after 1 month April, liver function recovery is normal, take 2 months again after, HBeAg (-), adhere to clothes after 6 months, HBsAg (±), HBV-DNA (-).

Example two, Zhang, woman, 9 years old, people from Daye City look into trouble hepatitis B, HBsAg (+) in May, 2000, HBeAg (+), anti-HBc (+), diet is depressed, right rib pain, bitter taste, body of the tongue is light red, the deep-thready pulse string, clothes soft-extract for treating hepatitis B 2 months, transference cure was obeyed soft-extract for treating hepatitis B 1 month again, look into HBeAg (-), liver function is normal.

Example three, Liu, man, 50 years old, Jiangxia District people look into trouble hepatitis B, HBsAg (+) in March, 2000, anti-HBe (+), anti-HBc (+), ALT150u/L, asymptomatic, began to obey soft-extract for treating hepatitis B 2 months March, ALT40u/L, the HBsAg titre descends, and obeys 2 months again, HBv-DNA (-), the HBsAg titre continues to descend.

Claims

1, a kind of soft-extract for treating hepatitis B is characterized in that making (weight in grams) by following prescription Chinese medicine: Herba Phyllanthi Urinariae 10-30 Herba Artemisiae Scopariae 10-40 Fructus Schisandrae Chinensis 10-30 Radix Pseudostellariae 10-25 Herba Ardisiae Japonicae 10-30 Fructus Crataegi 10-30 Fructus Ligustri Lucidi 10-30 Rhizoma Imperatae 10-25 Rhizoma Smilacis Glabrae 10-30 Radix Et Rhizoma Rhei 10-30 Radix Bupleuri 5-15 Radix Angelicae Sinensis 5-25 Semen Phaseoli 10-30 Radix Salviae Miltiorrhizae 10-30 Rhizoma Polygoni Cuspidati 5-20 Fructus Phyllanthi 5-25 Radix Isatidis 10-30 Radix Scutellariae 10-30

2, soft-extract for treating hepatitis B according to claim 1, it is characterized in that preparation method is: the medicine in the prescription is cleaned, the water logging of heating bubble 1 hour decocts extracting juice after 2 hours (juice for the first time), and medicinal residues decoct with water (slow fire) extracting juice (the juice second time) after 1 hour again behind the extracting juice, with twice medicine juice hybrid filtering, precipitate 24 hours, it is stand-by to get supernatant, this stand-by liquid is added Mel 1000 grams again and concentrates, in fast one-tenth cream, change cryoconcentration and become sweet cream, packaging sterilizing.