CN114869819A - Composition with anti-wrinkle effect and preparation method thereof - Google Patents

Abstract

The invention discloses a composition with anti-wrinkle effect and a preparation method thereof, belonging to the technical field of cosmetics. The composition with anti-wrinkle effect includes the following ingredients: sodium hyaluronate, yeast extract, sunflower seed extract, rose flower extract, hydrolyzed soybean protein, sesame seed oil, cetearyl alcohol and water. The invention adopts multiple plant extracts for compounding, has high safety, good product stability, good anti-wrinkle effect, and has a good market prospect.

Description

A kind of composition with anti-wrinkle effect and preparation method thereof

technical field

The invention relates to the technical field of cosmetics, in particular to a composition with anti-wrinkle effect and a preparation method thereof.

Background technique

There are many reasons for wrinkles. First, with the increase of age, the metabolism of the human body begins to slow down, the water and subcutaneous fat decrease, the elastic fibers gradually thicken, the skin becomes wrinkled, and the luster fades. Skin aging is a prominent manifestation of the aging of the whole body. Among them, facial skin aging is particularly obvious. The number of fibroblasts in the human body gradually decreases, and the collagen and elastin secreted by them are gradually reduced and broken due to oxidation, which supports the epidermis. The effect disappears, causing uneven collapse, the dermis begins to thin, the skin becomes less elastic, and wrinkles begin to appear gradually. Furthermore, the ultraviolet rays in the sun can also damage the dermis, causing it to dry and form small breaks, which are manifested in small wrinkles on the outside. In addition, habitual facial movements can exacerbate the appearance of wrinkles. For example, people who like to meditate have more wrinkles between their foreheads and brows; people who are emotionally rich and love to cry and laugh are prone to eye tail lines. There are also environmental pollution and work stress, smoking and drinking, weight changes, etc. can lead to wrinkles. Therefore, there is a high demand for skin care products with anti-wrinkle effects at present.

In the cosmetics market, Chinese herbal cosmetics account for about 30-40%, and people's needs for skin care are more comprehensive. Natural, safe, and less side effects are more favored by consumers. Due to the difficulty of developing traditional pure compound ingredients, long cycle, high cost, and easy to produce large irritating effects, natural Chinese herbal medicine has the advantages of being safer and easier to prepare. For example, Chinese patent application CN201910553174.3 discloses a moisturizing and anti-wrinkle composition and a skin care product. The moisturizing and anti-wrinkle composition of the present invention is composed of sodium hyaluronate, malto-oligosaccharide glucoside, mirorwood extract, etc. The compounding of seven components can make each component produce a significant synergistic effect. Skin care products containing the moisturizing and anti-wrinkle composition can achieve moisturizing by hydrating the skin with the small-molecule moisturizing components, and locking the skin through the macro-molecule moisturizing components. Moisture; at the same time, it promotes the production of hyaluronic acid through anti-aging ingredients, improves skin elasticity, increases the synthesis of collagen and elastic fibers, promotes cell activity, reduces muscle contraction, and has significant moisturizing and anti-wrinkle effects. The effect is short and the effect is obvious and lasting.

Sunflower seed oil is an important base oil raw material for cosmetics and has the effect of lubricating the skin. It has an activating effect on peroxidase-activated receptors, and has an anti-inflammatory effect that promotes skin wound healing; it can promote the decomposition of fat cells and has the effect of losing weight; it has a certain inhibitory effect on tyrosinase, and has a certain whitening effect. Rose flower extract plays a role in moisturizing and beautifying, skin care and beauty in cosmetics. Mullein, also known as ox-ear grass, big hairy leaf, one-pillar incense, tiger tail whip, bully whip, etc., is a biennial herb, up to 1.5 meters, and the whole plant is covered with dense and thick light gray-yellow star-shaped hairs. Basal leaves and lower cauline leaves are oblanceolate-oblong, base attenuates into short petioles, up to 15 cm long, 6 cm wide, with shallow crenulate margins, and upper stem leaves gradually narrow and gradually become Oblong to ovate-oblong, base extending into narrow wings. Its extract contains a variety of functional ingredients, which have the functions of anti-inflammatory and hemostasis, heat-clearing and detoxification, etc. When used in daily chemical products, it has the functions of tightening pores and moisturizing the skin, so that the skin can maintain a youthful state. In addition, there are studies proving that it has UV protection properties.

In view of the current situation that the anti-wrinkle effect of traditional Chinese medicine extract cosmetics is uneven, the present application provides a new composition with anti-wrinkle effect and a preparation method thereof. The traditional Chinese medicine extract is used for compounding to obtain better anti-wrinkle effect and product characteristics.

SUMMARY OF THE INVENTION

The purpose of the present invention is to provide a new composition with anti-wrinkle effect and a preparation method thereof, which are compounded by a variety of plant extracts, and have high safety, good product stability and good anti-wrinkle effect.

For realizing the above-mentioned purpose of the invention, the technical scheme of the present invention is as follows:

First, the present invention provides a composition with anti-wrinkle effect, comprising the following components: sodium hyaluronate, yeast extract, sunflower seed extract, rose flower extract, hydrolyzed soybean protein, sesame seed oil, cetearyl alcohol and water.

Preferably, the composition with anti-wrinkle effect comprises the following components in percentage by weight:

Sodium Hyaluronate 5-15%, Yeast Extract 8-15%, Sunflower Seed Extract 0.5-5%, Rose Flower Extract 10-15%, Hydrolyzed Soy Protein 0.2-1%, Sesame Seed Oil 0.5-5% , cetearyl alcohol 0.5-1.5% and water.

Further preferably, the composition with anti-wrinkle effect comprises the following components in percentage by weight:

Sodium Hyaluronate 10%, Yeast Extract 10-12%, Sunflower Seed Extract 1-3%, Rose Flower Extract 12%, Hydrolyzed Soy Protein 0.4-0.6%, Sesame Seed Oil 1-3%, Cetacean Hard Fatty alcohol 0.8-1.2% and water.

Most preferably, the composition with anti-wrinkle effect comprises the following components in percentage by weight:

Sodium Hyaluronate 10%, Yeast Extract 11%, Sunflower Seed Extract 2%, Rose Flower Extract 12%, Hydrolyzed Soy Protein 0.5%, Sesame Seed Oil 2%, Cetearyl Alcohol 1.0% and Water.

Preferably, the above-mentioned composition with anti-wrinkle effect further comprises Verbasil flower extract.

Further preferably, the weight ratio of the mullein extract and the sunflower seed extract is 1-3:1, more preferably 1.5:1.

Experiments have proved that adding mullein extract can further improve the anti-wrinkle effect of the composition. After adjusting different addition amounts, it is found that the anti-wrinkle effect is the best when the weight ratio of mullein extract and sunflower seed extract is 1-3:1.

Furthermore, the present invention provides the above-mentioned preparation method of the composition with anti-wrinkle effect, comprising the following steps:

(1) drop the sunflower seed extract of formula consumption, mullein extract, sesame seed oil, hydrolyzed soybean protein, cetearyl alcohol and water into stirring pot, heat, add yeast extract, homogenize, cool;

(2) After cooling, put the rose flower extract and sodium hyaluronate of the formula dosage into the mixer and stir to obtain the composition with the anti-wrinkle effect.

Preferably, in step (1), the heating temperature is 70-80°C.

Preferably, in step (1), the homogenization conditions are: 1200-18000r/min homogenization for 3-5min.

Preferably, in step (2), the stirring conditions are: stirring at a slow speed at room temperature for 0.5-1 h. in,

Slow stirring usually means that the stirring speed is below 500r/min.

Finally, the present invention provides the application of the above-mentioned composition with anti-wrinkle effect in the preparation of skin care products.

Wherein, the skin care products are toner, toner, toner, nutritional lotion, nutritional cream, massage cream, essence, eye cream, cleansing cream, cleansing foam, cleansing lotion, facial mask, powder cake, body lotion, At least one of a body cream, a body oil, and a body lotion.

The beneficial effects of the present invention are:

The invention provides a composition with anti-wrinkle effect, which has good anti-wrinkle effect; the composition of the formula is simple, and the compounding of traditional Chinese medicine extract components improves the safety; at the same time, the product has high stability and is convenient for storage and transportation; source of raw materials It is widely available in the market and has a good application prospect.

Detailed ways

In order to make the technical means, creative features, achievement goals and effects realized by the present invention easy to understand, the present invention will be further illustrated below in conjunction with specific embodiments, but the following embodiments are only preferred embodiments of the present invention, not all. Based on the examples in the implementation manner, other examples obtained by those skilled in the art without creative work shall fall within the protection scope of the present invention. In the following examples, unless otherwise specified, the operation methods used are conventional operation methods, the equipment used are conventional equipment, and the equipment materials used in each embodiment are the same.

The extract used in the present invention can be directly purchased raw materials on the market, or can be extracted through a certain process.

In the following examples, sodium hyaluronate is purchased from Guangzhou Yabao Chemical Co., Ltd., and the article number is

YBJC018;

Yeast lysate extract was purchased from Guangzhou Mingtu Biotechnology Co., Ltd.;

Sunflower seed extract was purchased from Guangzhou Lanyu Trading Co., Ltd.;

Rose flower extract was purchased from Guangzhou Mingtu Biotechnology Co., Ltd.;

Hydrolyzed soybean protein was purchased from Guangzhou Lanyu Trading Co., Ltd.;

Sesame seed oil was purchased from Guangzhou Yabao Chemical Co., Ltd., the item number is YBZT006;

Cetearyl alcohol was purchased from Guangzhou Yabao Chemical Co., Ltd., item number is YBJC009;

The mullein extract was prepared according to the following process: the mullein (provided by Yabao Chemical Industry) was extracted with 50% methanol, the material-to-liquid ratio was 1:10, the extract was heated in a water bath at 60° C., and concentrated to 1/3 of the original volume to obtain Mullein flower extract for use;

The water used was deionized water.

Preparation of the extract of Example 1

(1) Weigh the sunflower seed extract, mullein extract, sesame seed oil, hydrolyzed soybean protein, cetearyl alcohol and appropriate amount of water in the formula amount and put them into the stirring pot, heat to 75°C, and then add the yeast lysate The extract was homogenized by a homogenizer for 5min (the homogenization speed was 8000r/min);

(2) After cooling, put the rose extract and sodium hyaluronate into the mixer, and stir at a slow speed for 0.5h at normal temperature to prepare a composition with anti-aging effect.

The specific formula is shown in the following table:

Table 1.

result detection

1. Security test

The human skin closed patch test was carried out according to the human skin patch test stipulated in the "Safety Technical Specification for Cosmetics" (2015 edition). 35 volunteers were selected, and there were no suspicious reactions and positive reactions to the formula product of the present invention, which proved that the product of the present invention was safe and had no adverse reactions.

2. Stability test:

Detection method: Alternate cold and heat test, the obtained product is sealed and stored at 45°C, 25°C, -15°C for 24h in turn, after 5 cycles, placed at 25°C for 12h, and the product and the corresponding product newly prepared by the same method are thinly painted in black. Observe the board, compare the appearance, and grade as follows:

Table 2.

color (transparency) precipitation Layered Uniformity of application (compared to original product) 0 no change none none same 1 slightly changed small amount, difficult to distinguish Slightly layered Slightly uneven application 2 Significant change obvious precipitation Significant stratification Visibly difficult to apply evenly

The test results are as follows:

table 3.

The results in Table 3 show that the formulations A-L in the present invention have good stability, and there are no problems such as precipitation, discoloration, and delamination after the alternating cold and heat experiment.

3. Anti-wrinkle effect test

Detection method: skin elasticity test

130 volunteers, aged 43-55 years old, were selected and randomly divided into 13 groups with 10 participants in each group. Each group used the products prepared by formula A-L respectively, and one group did not use any product at the test site as a control. When using, apply 1mL of the product evenly to the entire inner forearm (about 10cm from the base of the palm, with an area of about 5 × 10cm), massage until fully absorbed, use it once a day in the morning and evening, and use it continuously for 4 weeks, during which no other skin care products are used in this area . The control group was scrubbed with water every morning and evening. The skin elasticity tester measures the elasticity of the application site before and after 4 weeks of use. The test of the same subject is carried out by the same instrument and the same tester. Before each measurement, clean the probe, and at the same time, the subject should wash the part to be tested with clean water, keep relaxed, sit still for 10 minutes, and accept the test.

Skin elasticity improvement rate = (Elasticity value after use - Elasticity value before use) / Elasticity value before use × 100%

The variation of the subject's elasticity value of formula B is shown in the following table:

Table 4.

subject number Elasticity value before use Elasticity value after use Elasticity increase value Skin elasticity improvement rate (%) 1 0.594 0.668 0.074 12.46% 2 0.436 0.48 0.044 10.09% 3 0.416 0.467 0.051 12.26% 4 0.534 0.591 0.057 10.67% 5 0.452 0.49 0.038 8.41% 6 0.483 0.545 0.062 12.84% 7 0.521 0.574 0.053 10.17% 8 0.514 0.553 0.039 7.59% 9 0.479 0.541 0.062 12.94% 10 0.558 0.609 0.051 9.14%

It can be seen that after the subject uses the product B of the present invention, the skin elasticity is significantly improved, the elasticity improvement value can reach 0.074, and the elasticity improvement rate can reach 12.94%. The compositions of the present application demonstrate that significant anti-wrinkle effects can be achieved.

The variation of the subject's elasticity value of formula G is shown in the following table:

table 5.

It can be seen that the improvement value of the skin elasticity of the subjects who use the product G is further improved compared to the subjects who use the product B, the improvement value of the skin elasticity can reach 0.127, and the improvement rate of the skin elasticity can reach 21.82%. It was proved that the addition of mullein extract further improved skin elasticity.

The measurement results of all formulations are as follows:

Table 6.

formula Skin elasticity improvement rate (%) control -0.24±1.32 A 9.51±3.37 B 10.66±1.92 C 10.83±1.73 D 11.75±1.66 E 11.59±2.38 F 14.37±1.82 G 15.12±3.82 H 14.61±2.14 I 13.90±1.54 J 3.85±2.14 K 1.34±0.85 L 2.72±1.13

It can be seen from the above results that the average skin elasticity improvement rate of formula A-I products can reach more than 9%, which has a good anti-wrinkle effect. Among them, the average skin elasticity improvement rate of formulas F-I can reach more than 13%, but H and I should not be selected considering the cost of mass production. On the whole, formulas F and G have the best anti-wrinkle effect.

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the scope of the present invention. within the scope of protection.

Claims (10)

1. The composition with the anti-wrinkle effect is characterized by comprising the following components: sodium hyaluronate, yeast extract, sunflower seed extract, rose extract, hydrolyzed soy protein, sesame seed oil, cetostearyl alcohol and water.

2. The composition with anti-wrinkle effect according to claim 1, wherein preferably the composition with anti-wrinkle effect comprises the following components in percentage by weight:

5-15% of sodium hyaluronate, 8-15% of yeast extract, 0.5-5% of sunflower seed extract, 10-15% of rose extract, 0.2-1% of hydrolyzed soybean protein, 0.5-5% of sesame seed oil, 0.5-1.5% of cetearyl alcohol and water.

3. The composition with anti-wrinkle effect according to claim 2, wherein the composition with anti-wrinkle effect comprises the following components in percentage by weight:

10% of sodium hyaluronate, 10-12% of yeast extract, 1-3% of sunflower seed extract, 12% of rose extract, 0.4-0.6% of hydrolyzed soybean protein, 1-3% of sesame seed oil, 0.8-1.2% of cetearyl alcohol and water.

4. The composition with anti-wrinkle effect according to claim 1, further comprising a mullein extract.

5. The composition with anti-wrinkle effect according to claim 4, wherein the weight ratio of the mullein extract to the sunflower seed extract is 1-3: 1.

6. the composition with anti-wrinkle effect according to claim 5, wherein the weight ratio of the mullein extract to the sunflower seed extract is 1.5: 1.

7. method for the preparation of a composition with anti-wrinkle effect according to any of claims 1 to 6, characterized in that it comprises the following steps:

(1) adding sunflower seed extract, mullein extract, oleum Sesami, hydrolyzed soybean protein, cetostearyl alcohol and water into a stirring pot, heating, adding yeast extract, homogenizing, and cooling;

(2) and cooling, putting the rose extract and the sodium hyaluronate into a mixer according to the formula dosage, and stirring to obtain the composition with the anti-wrinkle effect.

8. The method according to claim 7, wherein in the step (1), the heating temperature is 70-80 ℃, and the homogenizing conditions are as follows: homogenizing at 1200-.

9. The production method according to claim 7, wherein in the step (2), the stirring conditions are: stirring slowly at normal temperature for 0.5-1 h.

10. Use of the composition having an anti-wrinkle effect according to any one of claims 1 to 6 for the preparation of a skin care product, which is at least one of a toner, a smoothing toner, a firming toner, a nourishing lotion, a nourishing cream, a massage cream, a essence, an eye cream, a cleansing foam, a cleansing water, a mask, a pack, a body lotion, a body cream, a body oil and a body milk.