CN114796362A - Biological preparation for rust scratch repair cells - Google Patents
Biological preparation for rust scratch repair cells Download PDFInfo
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- CN114796362A CN114796362A CN202210523098.3A CN202210523098A CN114796362A CN 114796362 A CN114796362 A CN 114796362A CN 202210523098 A CN202210523098 A CN 202210523098A CN 114796362 A CN114796362 A CN 114796362A
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- repair cells
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- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 title claims abstract description 19
- 230000008439 repair process Effects 0.000 title claims abstract description 11
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 18
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 13
- 241000037740 Coptis chinensis Species 0.000 claims abstract description 13
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- 229940116229 borneol Drugs 0.000 claims abstract description 13
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 13
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 13
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 15
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- 239000011707 mineral Substances 0.000 claims description 5
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- 239000006041 probiotic Substances 0.000 claims description 5
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- 239000011425 bamboo Substances 0.000 abstract description 2
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Classifications
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- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a biological preparation for repairing cells of rust scratches, which comprises the following components in parts by weight: 0.5-1 part of callicarpa; 1-2 parts of south bamboo; 1-3 parts of borneol; 0.5-1.5 parts of scutellaria; 1-2 parts of bolbostemma paniculatum; 0.5-1 part of coptis chinensis; 1-3 parts of American ginseng; 3-4 parts of radix angelicae; 1-1.5 parts of mint; 3-5 parts of tetanus bacillus; 3-5 parts of iodophor, wherein the pearl grass, the nandina domestica thumb, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng are crushed by using a crusher, the pearl grass, the nandina domestica thumb, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng are cleaned and dried before being crushed by the crusher, and the dryer is used for drying, wherein the temperature is set to be 60 ℃. The biological preparation for rust scratch repair cells has the effect of cooling skin, so that the preparation is more skin-friendly, peculiar smell is prevented from being generated due to long-time isolation with air after the preparation is coated and wrapped, the use comfort of a patient is improved, wound deterioration is avoided, pure plants are configured, skin absorption is benefited, the speed of wound healing is improved, and the curative effect is exact.
Description
Technical Field
The invention belongs to the technical field of biological preparations, and particularly relates to a biological preparation for repairing cells of rust scratches.
Background
Various preparations in various forms, which are prepared from various carbon-based organisms with medical and research values by the traditional technology or the modern biotechnology and are used for preventing (health care), treating and diagnosing various physiological symptoms of human bodies, are collectively called biological preparations.
The biological preparation is an "immune biological preparation" in the medical industry, and is a biological product which is processed by using effective antigen components of microorganisms (bacteria, rickettsia, viruses and the like) and metabolites thereof, animal toxins, blood or tissues of human beings or animals and the like and is used for preventing, treating and diagnosing corresponding infectious diseases or other related diseases.
The wound patient is easy to be invaded by various bacteria to cause wound infection because the natural barriers of skin and mucous membrane are lost, the wound infection is a pathological reaction of tissue injury pathological changes caused by pathogenic microorganisms invading the body through the wound, and particularly, the wound scratched by rust is more pertinently repaired.
Disclosure of Invention
The invention aims to provide a biological agent for repairing cells by rust scratching, so as to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme: a biological preparation for repairing cells of rust scratches comprises the following components in parts by weight: 0.5-1 part of callicarpa bodinieri, 1-2 parts of Nanzhu, 1-3 parts of borneol, 0.5-1.5 parts of scutellaria baicalensis, 1-2 parts of rhizoma bolbostemmae, 0.5-1 part of coptis chinensis, 1-3 parts of American ginseng, 3-4 parts of radix angelicae, 1-1.5 parts of mint, 3-5 parts of tetanus bacillus and 3-5 parts of iodophor.
Preferably, the pearl grass, the Nandina domestica, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng are crushed by a crusher.
Preferably, the pearl grass, the south bamboo, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng are cleaned and dried before being crushed by a crusher, and a dryer is used for drying, the temperature is set to be 60 ℃, the time is set to be 5min, and the added liquid is obtained for standby.
Preferably, the mint, the tetanus bacillus and the iodophor are put into a container, 2-3 times of water is added, the mixture is soaked for 10min and then stirred, mixed liquid is obtained and then put into high-temperature sterilization equipment for sterilization, and the sterilization is carried out by steam at the temperature of below 100 ℃.
Preferably, the obtained sterilized mixed liquid is reacted in a reaction kettle, when the temperature in the reaction kettle exceeds 100 ℃, cooling water is introduced into a water jacket between a magnetic stirrer and a kettle cover when the temperature is ensured to be lower than 35 ℃, 2-3 parts of honeysuckle, 0.5-1.5 parts of beeswax and 2-3 parts of rhizoma arisaematis are added, and the mixed liquid is obtained after the reaction.
Preferably, the obtained mixed liquid is taken out from the reaction kettle and mixed and stirred with the standby added liquid, and the mixed liquid is placed into a container for standing for 1 to 2 days and then is placed into a fermentation tank for fermentation.
Preferably, 3-5 parts of plant culture solution is added into a fermentation tank in the fermentation process, 5-10% of probiotics are inoculated into the fermentation tank, the fermentation time is 23-38 ℃, and the fermentation time is 45-60 days.
Preferably, mineral trace elements are added after fermentation is finished, and 1-5% of nutrient solution is supplemented to obtain the biological preparation.
The invention has the technical effects and advantages that: this a biological agent for rust fish tail repairing cells, make the treatment to skin wound better through the improvement to biological agent, disinfect to the rust, avoid rust irritation wound to cause secondary damage, play positive effect to skin treatment, the effect of cool skin still has simultaneously, make preparation more skin-friendly, avoid smearing to wrap the back because of the isolated peculiar smell that produces of long-time and air, promote patient's use comfort, avoid the wound to worsen, and the configuration of pure plant processing, be of value to skin absorption, improve wound healing's speed, the curative effect is exact, there is not other side effects.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The technical scheme of the invention is further explained by combining the embodiment as follows:
example one
The manufacturing process of the degradable water-resistant pulp molded lunch box in the embodiment comprises the following steps:
the components in parts by weight are as follows: 1-2 parts of callicarpa bodinieri, 2-3 parts of Nanzhu, 2-4 parts of borneol, 2-3 parts of scutellaria baicalensis, 1-2 parts of rhizoma bolbostemmae, 0.5-1 part of coptis chinensis, 2-3 parts of American ginseng, 3-5 parts of angelica dahurica, 0.5-2 parts of mint, 3-5 parts of tetanus bacillus and 3-4 parts of iodophor.
Crushing the chloranthus japonicus, the Nandina domestica, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng by using a crusher.
Cleaning herba Phyllanthi Urinariae, Nandina domestica, Borneolum Syntheticum, radix Scutellariae, rhizoma Bolbostematis, rhizoma Coptidis, and radix Panacis Quinquefolii, oven drying at 50 deg.C for 8min to obtain an additive liquid.
Putting herba Menthae, tetanus bacillus and iodophor into a container, adding 1.5-2 times of water, soaking for 12min, stirring to obtain a mixed liquid, sterilizing in a high temperature sterilization device, and sterilizing with steam at 100 deg.C or below.
And (3) reacting the obtained sterilized mixed liquid in a reaction kettle, wherein when the temperature in the reaction kettle exceeds 100 ℃, cooling water is introduced into a water jacket between a magnetic stirrer and a kettle cover when the temperature is ensured to be lower than 35 ℃, 3-4 parts of honeysuckle, 1-2 parts of beeswax and 1.5-2.5 parts of rhizoma arisaematis are added, and the mixed liquid is obtained after the reaction.
Taking out the obtained mixed liquid from the reaction kettle, mixing and stirring the mixed liquid with the standby added liquid, placing the mixed liquid into a container for standing for 1-2 days, and then placing the mixed liquid into a fermentation tank for fermentation.
Adding 3-5 parts of plant culture solution into a fermentation tank during fermentation, inoculating 15-130% of probiotic groups into the fermentation tank, and fermenting at 17-28 deg.C for 45-50 days.
After fermentation, mineral trace elements are added and 1-5% of nutrient solution is supplemented to obtain the biological preparation.
Example two
The manufacturing process of the degradable water-resistant pulp molded lunch box in the embodiment comprises the following steps:
the components in parts by weight are as follows: 1.5-2 parts of callicarpa bodinieri, 0.5-1.5 parts of nandina, 3-5 parts of borneol, 1-3 parts of scutellaria baicalensis, 0.5-1.5 parts of rhizoma bolbostemmae, 4-6 parts of coptis chinensis, 2-3 parts of American ginseng, 3-4 parts of radix angelicae, 1-1.5 parts of mint, 2-3.5 parts of tetanus bacillus and 4-6 parts of iodophor.
Crushing the chloranthus japonicus, the Nandina domestica, the borneol, the scutellaria baicalensis, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng by using a crusher.
Cleaning and drying herba Phyllanthi Urinariae, Nanzhu, Borneolum Syntheticum, Scutellariae radix, rhizoma Bolbostematis, Coptidis rhizoma, and radix Panacis Quinquefolii before crushing with a crusher, and drying with a dryer at 55 deg.C for 15min to obtain an additive liquid.
Putting herba Menthae, tetanus bacillus and iodophor into a container, adding 3-4 times of water, soaking for 15min, stirring to obtain a mixed liquid, and sterilizing in a high temperature sterilization device with steam sterilization at 100 deg.C or below.
And (3) reacting the obtained sterilized mixed liquid in a reaction kettle, wherein when the temperature in the reaction kettle exceeds 100 ℃, cooling water is introduced into a water jacket between a magnetic stirrer and a kettle cover when the temperature is ensured to be lower than 35 ℃, 2-3 parts of honeysuckle, 0.5-1.5 parts of beeswax and 1.5-2.5 parts of rhizoma arisaematis are added, and the mixed liquid is obtained after the reaction.
Taking out the obtained mixed liquid from the reaction kettle, mixing and stirring the mixed liquid with the standby added liquid, placing the mixed liquid into a container for standing for 2-3 days, and then placing the mixed liquid into a fermentation tank for fermentation.
Adding 3-5 parts of plant culture solution into a fermentation tank during fermentation, inoculating 5-10% of probiotic flora into the fermentation tank, and fermenting at 30-40 deg.C for 50-55 days.
After fermentation, mineral trace elements are added and 5-10% of nutrient solution is supplemented to obtain the biological preparation.
EXAMPLE III
The manufacturing process of the degradable water-resistant pulp molded lunch box in the embodiment comprises the following steps:
the components in parts by weight are as follows: 2-3 parts of callicarpa bodinieri, 4-6 parts of Nanzhu, 3-5 parts of borneol, 2-3 parts of scutellaria baicalensis, 2-3 parts of rhizoma bolbostemmae, 3-5 parts of coptis chinensis, 3-5 parts of American ginseng, 2-3 parts of radix angelicae, 2-3 parts of mint, 5-5 parts of tetanus bacillus and 2-3 parts of iodophor.
Pulverizing ZHUCAO, Nanzhu, Borneolum Syntheticum, Scutellariae radix, rhizoma Bolbostematis, Coptidis rhizoma, and radix Panacis Quinquefolii with a crusher.
Cleaning herba Phyllanthi Urinariae, Nandina domestica, Borneolum Syntheticum, radix Scutellariae, rhizoma Bolbostematis, rhizoma Coptidis, and radix Panacis Quinquefolii, oven drying at 70 deg.C for 4min to obtain an additive liquid.
Putting herba Menthae, tetanus bacillus and iodophor into a container, adding 1-3 times of water, soaking for 13min, stirring to obtain a mixed liquid, sterilizing in a high temperature sterilization device, and sterilizing with steam at 100 deg.C or below.
And (3) reacting the obtained sterilized mixed liquid in a reaction kettle, wherein when the temperature in the reaction kettle exceeds 100 ℃ in working, cooling water is introduced into a water jacket between a magnetic stirrer and a kettle cover, the water temperature is ensured to be lower than 35 ℃, 0.5-2 parts of honeysuckle, 1-3 parts of beeswax and 3-5 parts of rhizoma arisaematis are added, and the mixed liquid is obtained after reaction.
Taking out the obtained mixed liquid from the reaction kettle, mixing and stirring the mixed liquid with the standby added liquid, placing the mixed liquid into a container for standing for 4 days, and then placing the mixed liquid into a fermentation tank for fermentation.
Adding 5 parts of plant culture solution into a fermentation tank during fermentation, inoculating 15-10% of probiotic groups into the fermentation tank, and fermenting at 23-38 deg.C for 60 days.
After fermentation, mineral trace elements are added and 15% of nutrient solution is supplemented to obtain the biological preparation.
The preparation can be applied by cotton bud, and wound is allowed to stand, or the preparation is applied to wound and wrapped with gauze, and the preparation is stored in cool and dry place to avoid exposure to sunlight.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments or portions thereof without departing from the spirit and scope of the invention.
Claims (8)
1. A biological agent for rust scratch repair cells, which is characterized in that: the components in parts by weight are as follows: 0.5-1 part of callicarpa bodinieri, 1-2 parts of Nanzhu, 1-3 parts of borneol, 0.5-1.5 parts of scutellaria baicalensis, 1-2 parts of rhizoma bolbostemmae, 0.5-1 part of coptis chinensis, 1-3 parts of American ginseng, 3-4 parts of radix angelicae, 1-1.5 parts of mint, 3-5 parts of tetanus bacillus and 3-5 parts of iodophor.
2. The biological agent for rust scratch repair cells according to claim 1, wherein: the Phyllanthus niruri, Nandina domestica, Borneolum Syntheticum, radix Scutellariae, rhizoma Bolbostematis, rhizoma Coptidis, and radix Panacis Quinquefolii are crushed by a crusher.
3. The biological agent for rust scratch repair cells according to claim 2, wherein: cleaning and drying the chloranthus japonicus, the Nandina domestica Thunb, the borneol, the radix scutellariae, the rhizoma bolbostemmae, the coptis chinensis and the American ginseng before crushing by a crusher, and drying by using a dryer at the temperature of 60 ℃ for 5min to obtain an added liquid for later use.
4. The biological agent for rust scratch repair cells according to claim 3, wherein: putting the mint, the tetanus bacillus and the iodophor into a container, adding 2-3 times of water, soaking for 10min, stirring to obtain a mixed liquid, putting the mixed liquid into high-temperature sterilization equipment for sterilization, and performing steam sterilization at the temperature of below 100 ℃.
5. The biological agent for rust scratch repair cells according to claim 4, wherein: and reacting the obtained sterilized mixed liquid in a reaction kettle, wherein when the temperature in the kettle exceeds 100 ℃ in work, cooling water is introduced into a water jacket between a magnetic stirrer and a kettle cover, the water temperature is ensured to be less than 35 ℃, and 2-3 parts of honeysuckle, 0.5-1.5 parts of beeswax and 2-3 parts of rhizoma arisaematis are added to obtain the mixed liquid after reaction.
6. The biological agent for rust scratch repair cells according to claim 5, wherein: taking out the obtained mixed liquid from the reaction kettle, mixing and stirring the mixed liquid with the standby added liquid, placing the mixed liquid into a container for standing for 1-2 days, and then placing the mixed liquid into a fermentation tank for fermentation.
7. The biological agent for rust scratch repair cells according to claim 6, wherein: adding 3-5 parts of plant culture solution into a fermentation tank during fermentation, inoculating 5-10% of probiotic flora into the fermentation tank, and fermenting at 23-38 deg.C for 45-60 days.
8. The biological agent for rust scratch repair cells according to claim 7, wherein: after fermentation, mineral trace elements are added and 1-5% of nutrient solution is supplemented to obtain the biological preparation.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721529A (en) * | 2010-01-26 | 2010-06-09 | 江苏天际药业有限公司 | Composition with functions of clearing heat and detoxicating and preparation method thereof |
| CN104857312A (en) * | 2015-06-19 | 2015-08-26 | 王桂霞 | Traditional Chinese medicine composition for preventing and controlling wound infection and promoting wound repair |
| CN108272959A (en) * | 2018-03-26 | 2018-07-13 | 华南农业大学 | A kind of herbal mixture and its preparation method and application |
| CN111265594A (en) * | 2018-12-04 | 2020-06-12 | 苏州沃立医疗科技有限公司 | Medicinal preparation for repairing wound and preparation method thereof |
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2022
- 2022-05-13 CN CN202210523098.3A patent/CN114796362A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101721529A (en) * | 2010-01-26 | 2010-06-09 | 江苏天际药业有限公司 | Composition with functions of clearing heat and detoxicating and preparation method thereof |
| CN104857312A (en) * | 2015-06-19 | 2015-08-26 | 王桂霞 | Traditional Chinese medicine composition for preventing and controlling wound infection and promoting wound repair |
| CN108272959A (en) * | 2018-03-26 | 2018-07-13 | 华南农业大学 | A kind of herbal mixture and its preparation method and application |
| CN111265594A (en) * | 2018-12-04 | 2020-06-12 | 苏州沃立医疗科技有限公司 | Medicinal preparation for repairing wound and preparation method thereof |
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| 上海第二医学院主编, 人民卫生出版社 * |
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Application publication date: 20220729 |