CN108553538A - The women bacteriostatic gel of anticancer function - Google Patents
The women bacteriostatic gel of anticancer function Download PDFInfo
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- CN108553538A CN108553538A CN201810377979.2A CN201810377979A CN108553538A CN 108553538 A CN108553538 A CN 108553538A CN 201810377979 A CN201810377979 A CN 201810377979A CN 108553538 A CN108553538 A CN 108553538A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses feminine hygiene articles technical field, specific field is the women bacteriostatic gel of anticancer function, and raw material composition and corresponding weight percent are：Kuh-seng 7%~8%, frutus cnidii 5%~7%, safflower 5%~6%, the fruit of summer cypress 4%~6%, Cortex Phellodendri 4%~5%, garden burnet 3%~5%, pear juice tunning 3%~5% etc., pear juice after lactobacillus leavening agent ferments is containing there are many organic acids, the vaginal environment being destroyed can be repaired, adjusting pH value makes it be conducive to the breeding of commensal bacteria, to inhibit harmful microorganism to breed, it is restricted each other between vaginal flora, inhibit pathologic bacterial action, restore the balance of vaginal flora, pear juice tunning plays a role for plurality of Chinese and provides good environment, to reach drug effect it is rapid while fungistatic effect it is also preferable, the symptom that women intravaginal occurs is set to be effected a radical cure rapidly, it prevents from now further deteriorating and causing the malignant diseases such as cervical carcinoma.
Description
Technical field
The present invention relates to feminine hygiene articles technical field, specific field is the women bacteriostatic gel of anticancer function.
Background technology
Women bacteriostatic gel is one of feminine hygiene articles, and the shield of washing for being mainly used for vulva and vagina cleans, main work(
Effect is, with cleaning bacteriostasis, vaginal flora is complex, and microorganism therein is divided into pathologic and commensalism in turn, various
It being grown between microorganism in same environment, there may be anti-effects short of money between each microorganism, when pH value is 3.8~4.2,
Be conducive to the breeding of commensal bacteria, especially Bacillus acidi lactici, to ensure the important strain of vaginal health, can inhibit harmful microorganism
It breeds, is restricted each other between vaginal flora, inhibit pathologic bacterial action, but once balance is destroyed, intravaginal pH value is uncomfortable
Lactobacillus growth is closed, Bacillus acidi lactici is lost ground, and pathologic bacterial reproduction then will appear symptom, and existing bacteriostatic gel is general
For Chinese medicine type or nutrient type, that there are bacteriostatic rates is slow for the bacteriostatic gel of Chinese medicine type, and auxotype bacteriostatic gel has suppression
The deficiency of bacterium effect difference, when the symptom occurred in vagina is unable to get rapid radical cure, it may appear that further deteriorate, sternly
Virus can be entered by vagina in uterine cavity when weight, cause the malignant diseases such as cervical carcinoma, need the female for developing anticancer function thus
Property bacteriostatic gel.
Invention content
It is mentioned above in the background art to solve the purpose of the present invention is to provide the women bacteriostatic gel of anticancer function
Problem.
To achieve the above object, the present invention provides the following technical solutions：The women bacteriostatic gel of anticancer function, raw material
Composition and corresponding weight percent are：Kuh-seng 7%~8%, frutus cnidii 5%~7%, safflower 5%~6%, the fruit of summer cypress 4%~
6%, Cortex Phellodendri 4%~5%, garden burnet 3%~5%, pear juice tunning 3%~5%, ethyl alcohol 2%~3%, glycerine 1%~3%,
Borneol 1%~1.5%, menthol 1%~1.5%, remaining is distilled water.
Preferably, the volume fraction of the ethyl alcohol is 70%~75%.
Preferably, the preparation method of the pear juice tunning is：
1) after cleaning pears then peeled and cored is squeezed the juice, and is filtered out the residue in pear juice using filtering gauze；
2) automatic electric heating pressure sterilization device is used to carry out high-temperature sterilization processing to the prepared product in step 1)；
3) prepared product in step 2) is positioned in fermentation tank, lactobacillus leavening agent, the lactobacillus ferment is then added
Agent is 1 with prepared product volume ratio in step 2):800~1000, fermentation jar temperature is set as 20~24 DEG C, fermentation time 7
It.
Preferably, the women bacteriostatic gel of anticancer function, preparation method are：
1) kuh-seng, frutus cnidii, safflower, the fruit of summer cypress, Cortex Phellodendri, garden burnet are thrown to Chinese medicine saucepan according to corresponding weight percent
In, distilled water is then added, distilled water is heated to boiling, after the 10~15min that boils, adjustment temperature is to 70~80 DEG C, while enduring
Side processed is stirred, and after 20~25min, is stopped stirring and heating, the dregs of a decoction is filtered out, medicine soup is spare；
2) ethyl alcohol and glycerine are added to by corresponding weight percent in step 1) prepared product, are stirring evenly and then adding into ice
Piece, menthol and pear juice tunning stir the mixture for uniformly again；
3) it after prepared product in step 2) being positioned over 20~40min under room temperature, can be used in gel state.
The beneficial effects of the invention are as follows：The women bacteriostatic gel of anticancer function, kuh-seng, frutus cnidii, safflower, the fruit of summer cypress, Huang
Cypress, garden burnet are the Chinese medicine for having effects that inhibiting bacteria and diminishing inflammation, in vagina various symptoms abnormal leucorrhea, itch, cusalgia,
There are peculiar smell and redness etc., there is elimination effect, wherein kuh-seng and frutus cnidii have effects that heat-clearing and damp-drying drug, cures mainly itch, redness, in vain
Band exception and trichomonas vaginitis, safflower have function of promoting blood circulation to disperse blood clots, have effects that dissipate wet effect going to swell, the fruit of summer cypress and Cortex Phellodendri have clear
It is pyrolyzed toxic action, cures mainly itch, peculiar smell, garden burnet has effects that inhibit a variety of cure the disease microorganism and tumours, using plurality of Chinese
It is used in conjunction with each other, vaginal symptoms can be made effectively to be effected a radical cure, the addition of ethyl alcohol and glycerine improves borneol and menthol is mixing
Solubility in object, borneol and menthol have refrigerant antipruritic, clearing heat and detoxicating effect, it is non-stimulated to vagina simultaneously, can be rapid
Mitigate female private part sense of discomfort, the quick-acting of the women bacteriostatic gel of anticancer function is improved, after lactobacillus leavening agent ferments
Pear juice contains there are many organic acid, can repair the vaginal environment being destroyed, and adjusting pH value makes it be conducive to the breeding of commensal bacteria, to
Inhibit harmful microorganism breeding, restricted each other between vaginal flora, inhibit pathologic bacterial action, restores the flat of vaginal flora
Weighing apparatus, pear juice tunning are that plurality of Chinese plays a role and provides good environment, to reach drug effect it is rapid while fungistatic effect
Also preferably, so that the symptom that women intravaginal occurs is effected a radical cure rapidly, prevent from now further deteriorating and causing the evils such as cervical carcinoma
Property disease.
Specific implementation mode
Below in conjunction with the embodiment of the present invention, technical scheme of the present invention is clearly and completely described, it is clear that institute
The embodiment of description is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention,
Every other embodiment obtained by those of ordinary skill in the art without making creative efforts, belongs to this hair
The range of bright protection.
Embodiment 1：
Pear juice tunning is prepared first：
1) after cleaning pears then peeled and cored is squeezed the juice, and is filtered out the residue in pear juice using filtering gauze；
2) automatic electric heating pressure sterilization device is used to carry out high-temperature sterilization processing to the prepared product in step 1)；
3) prepared product in step 2) is positioned in fermentation tank, lactobacillus leavening agent, the lactobacillus ferment is then added
Agent is 1 with prepared product volume ratio in step 2):800, fermentation jar temperature is set as 20 DEG C, fermentation time is 7 days.
Then the women bacteriostatic gel of anticancer function is prepared：
1) it is 7% kuh-seng, 5% frutus cnidii, 5% safflower, 4% fruit of summer cypress, 4% Cortex Phellodendri, the throwing of 3% garden burnet by weight percent
It puts into Chinese medicine saucepan, 64% distilled water is then added, distilled water is heated to boiling, after the 10min that boils, adjustment temperature to 70
DEG C, it is stirred in tanning, after 20min, stops stirring and heating, the dregs of a decoction are filtered out, medicine soup is spare；
2) it is that 2% ethyl alcohol and 1% glycerine are added in step 1) prepared product by weight percent, is stirring evenly and then adding into
1% borneol, 1% menthol and 3% pear juice tunning stir the mixture for uniformly again；
3) it after prepared product in step 2) being positioned over 20min under room temperature, can be used in gel state.
Embodiment 2：
Pear juice tunning is prepared first：
1) after cleaning pears then peeled and cored is squeezed the juice, and is filtered out the residue in pear juice using filtering gauze；
2) automatic electric heating pressure sterilization device is used to carry out high-temperature sterilization processing to the prepared product in step 1)；
3) prepared product in step 2) is positioned in fermentation tank, lactobacillus leavening agent, the lactobacillus ferment is then added
Agent is 1 with prepared product volume ratio in step 2):900, fermentation jar temperature is set as 22 DEG C, fermentation time is 7 days.
Then the women bacteriostatic gel of anticancer function is prepared：
1) it is 7.5% kuh-seng, 6% frutus cnidii, 5.5% safflower, 5% fruit of summer cypress, 4.5% Cortex Phellodendri, 4% by weight percent
Garden burnet is thrown in Chinese medicine saucepan, and 56% distilled water is then added, and distilled water is heated to boiling, after the 12min that boils, adjustment temperature
Degree is stirred to 75 DEG C in tanning, after 22min, is stopped stirring and heating, the dregs of a decoction is filtered out, medicine soup is spare；
2) it is that 2.5% ethyl alcohol and 2% glycerine are added in step 1) prepared product by weight percent, is stirring evenly and then adding into
1.5% borneol, 1.5% menthol and 4% pear juice tunning stir the mixture for uniformly again；
3) it after prepared product in step 2) being positioned over 30min under room temperature, can be used in gel state.
Embodiment 3：
Pear juice tunning is prepared first：
1) after cleaning pears then peeled and cored is squeezed the juice, and is filtered out the residue in pear juice using filtering gauze；
2) automatic electric heating pressure sterilization device is used to carry out high-temperature sterilization processing to the prepared product in step 1)；
3) prepared product in step 2) is positioned in fermentation tank, lactobacillus leavening agent, the lactobacillus ferment is then added
Agent is 1 with prepared product volume ratio in step 2):1000, fermentation jar temperature is set as 24 DEG C, fermentation time is 7 days.
Then the women bacteriostatic gel of anticancer function is prepared：
1) it is 8% kuh-seng, 7% frutus cnidii, 6% safflower, 6% fruit of summer cypress, 5% Cortex Phellodendri, the throwing of 5% garden burnet by weight percent
It puts into Chinese medicine saucepan, 49% distilled water is then added, distilled water is heated to boiling, after the 15min that boils, adjustment temperature to 80
DEG C, it is stirred in tanning, after 25min, stops stirring and heating, the dregs of a decoction are filtered out, medicine soup is spare；
2) it is that 3% ethyl alcohol and 3% glycerine are added in step 1) prepared product by weight percent, is stirring evenly and then adding into
1.5% borneol, 1.5% menthol and 5% pear juice tunning stir the mixture for uniformly again；
3) it after prepared product in step 2) being positioned over 40min under room temperature, can be used in gel state.
It invites 50 subjects to use the women bacteriostatic gel of the anticancer function of Examples 1 to 3 preparation respectively, uses Chinese medicine
The existing women bacteriostatic gel of type and nutrient type as a comparison case 1 and comparative example 2, frequency of use is 1 time a day, to investigate
Symptom is itch, cusalgia and secretion exception etc., and record result is as follows,
As seen from the experiment, the women bacteriostatic gel of anticancer function of the present invention is in contrast to existing women bacteriostatic gel drug effect
Rapid and good antimicrobial effect, makes the symptom that women intravaginal occurs be effected a radical cure rapidly, prevents from now further deteriorating and causing
The malignant diseases such as cervical carcinoma.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with
Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace
And modification, the scope of the present invention is defined by the appended.
Claims (4)
1. the women bacteriostatic gel of anticancer function, it is characterised in that：Its raw material forms and corresponding weight percent is：Kuh-seng
7%~8%, frutus cnidii 5%~7%, safflower 5%~6%, the fruit of summer cypress 4%~6%, Cortex Phellodendri 4%~5%, garden burnet 3%~
5%, pear juice tunning 3%~5%, ethyl alcohol 2%~3%, glycerine 1%~3%, borneol 1%~1.5%, menthol 1%~
1.5%, remaining is distilled water.
2. the women bacteriostatic gel of anticancer function according to claim 1, it is characterised in that：The volume fraction of the ethyl alcohol
It is 70%~75%.
3. the women bacteriostatic gel of anticancer function according to claim 1, it is characterised in that：The pear juice tunning
Preparation method is：
1) after cleaning pears then peeled and cored is squeezed the juice, and is filtered out the residue in pear juice using filtering gauze；
2) automatic electric heating pressure sterilization device is used to carry out high-temperature sterilization processing to the prepared product in step 1)；
3) prepared product in step 2) is positioned in fermentation tank, is then added lactobacillus leavening agent, the lactobacillus leavening agent with
Prepared product volume ratio is 1 in step 2):800~1000, fermentation jar temperature is set as 20~24 DEG C, fermentation time is 7 days.
4. the women bacteriostatic gel of anticancer function according to claim 1, it is characterised in that：Preparation method is：
1) kuh-seng, frutus cnidii, safflower, the fruit of summer cypress, Cortex Phellodendri, garden burnet are thrown to according to corresponding weight percent in Chinese medicine saucepan,
Then distilled water is added, distilled water is heated to boiling, after the 10~15min that boils, adjustment temperature is to 70~80 DEG C, in tanning
It stirs, after 20~25min, stops stirring and heating, the dregs of a decoction are filtered out, medicine soup is spare；
2) ethyl alcohol and glycerine are added to by corresponding weight percent in step 1) prepared product, are stirring evenly and then adding into borneol, thin
Lotus brain and pear juice tunning stir the mixture for uniformly again；
3) it after prepared product in step 2) being positioned over 20~40min under room temperature, can be used in gel state.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810377979.2A CN108553538A (en) | 2018-04-25 | 2018-04-25 | The women bacteriostatic gel of anticancer function |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110613839A (en) * | 2019-10-28 | 2019-12-27 | 田兰 | Chinese medicinal biological preparation for acting on female reproductive system and preparation method thereof |
| CN111000955A (en) * | 2019-12-30 | 2020-04-14 | 重庆宫妙生物科技有限公司 | Firming antibacterial gel and preparation method thereof |
| CN111000954A (en) * | 2019-12-30 | 2020-04-14 | 重庆宫妙生物科技有限公司 | Antibacterial gel and preparation method thereof |
| CN111012859A (en) * | 2019-12-30 | 2020-04-17 | 重庆宫妙生物科技有限公司 | Bacteriostatic external pill of composite biological preparation |
| CN111053893A (en) * | 2019-12-30 | 2020-04-24 | 重庆宫妙生物科技有限公司 | Antibacterial effervescent tablet and preparation method thereof |
| CN111053872A (en) * | 2019-12-30 | 2020-04-24 | 重庆宫妙生物科技有限公司 | Antibacterial liquid and preparation method thereof |
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| CN107375068A (en) * | 2017-07-25 | 2017-11-24 | 广州铭心化妆品有限公司 | A kind of hormone is releived Essence and preparation method thereof |
Cited By (6)
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