CN108261515A - It is a kind of to be used to prevent Chinese medicine composition, Chinese medicine microecological preparation of cad pig and its preparation method and application - Google Patents
It is a kind of to be used to prevent Chinese medicine composition, Chinese medicine microecological preparation of cad pig and its preparation method and application Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
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- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/233—Bupleurum
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
Abstract
The present invention relates to a kind of for preventing Chinese medicine composition, Chinese medicine microecological preparation of cad pig and its preparation method and application, belong to veterinary drug technical field.The Chinese medicine composition for being used to prevent cad pig of the present invention, is made of the component of following parts by weight：50~70 parts of Radix Astragali, 50~70 parts of Radix Angelicae Sinensis, 50~70 parts of Radix Codonopsis, 50~70 parts of honeysuckle, 50~70 parts of the coptis, 50~70 parts of rhizoma atractylodis, 30~40 parts of Rhizoma Atractylodis Macrocephalae, 30~40 parts of cimicifugae foetidae, 30~40 parts of radix bupleuri, 30~40 parts of Poria cocos, 20~30 parts of green peel, 20~30 parts of dried orange peel, 15~25 parts of hawthorn, 15~25 parts of malt, 15~25 parts of Medicated Leaven.The Chinese medicine composition for being used to prevent cad pig of the present invention has the effects that strengthen immunity, rich in nutrition, stomach invigorating promote digestion, antiviral, antibacterial, resisting stress, and by improving piglet disease-resistant power, to prevent piglet disease occurs for adjustment piglet spleen and stomach function.
Description
Technical field
The present invention relates to a kind of for preventing Chinese medicine composition, Chinese medicine microecological preparation of cad pig and preparation method thereof and answering
With belonging to veterinary drug technical field.
Background technology
At present, early weaning piglet technology is widely used, and substantially increases the reproductive efficiency of sow, still, due to piglet
Weaning Age is more early, and autoimmunity and premunition are poor, and various diseases easily occur, and causes piglet slow-growing or even is formed
A large amount of cad pigs reduce the culture efficiency on pig farm.The formation of cad pig has following reason：(1) wean before and after stress, due to itself
Immunity is poor, virus and bacterial infection easily occurs, such as smoothing filter operator, swine fever, colibacillosis are that piglet is normal
Send out disease；(2) piglet abilities of digestive and absorption is weaker, and weaning stress often results in it and pathogenicity or trophism diarrhea occurs, and causes son
Pig appetite is depressed, mental status is poor or even disease occurs；(3) it is prevention and treatment weanling pig morbidity, often feeds a large amount of antibiosis
Element causes organ damage；(4) nursing period and feeding management, nutrition condition after wean are poor.More than reason interacts, if not
It can properly settle, the probability that piglet forms cad pig greatly increases, and finally improves the mortality of the sick and weak piglet in pig farm.
Invention content
The object of the present invention is to provide a kind of for preventing the Chinese medicine composition of cad pig, improves the growth speed of sick and weak porkling
Degree reduces the quantity of cad pig.
The present invention also provides a kind of for preventing Chinese medicine microecological preparation of cad pig and its preparation method and application.
In order to achieve the goal above, technical solution is used by the Chinese medicine composition for being used to prevent cad pig of the present invention：
A kind of Chinese medicine composition for being used to prevent cad pig, is made of the component of following parts by weight：50~70 parts of Radix Astragali, Radix Angelicae Sinensis
50~70 parts, 50~70 parts of Radix Codonopsis, 50~70 parts of honeysuckle, 50~70 parts of the coptis, 50~70 parts of rhizoma atractylodis, 30~40 parts of Rhizoma Atractylodis Macrocephalae,
30~40 parts of cimicifugae foetidae, 30~40 parts of radix bupleuri, 30~40 parts of Poria cocos, 20~30 parts of green peel, 20~30 parts of dried orange peel, hawthorn 15~25
Part, 15~25 parts of malt, 15~25 parts of Medicated Leaven.
In the Chinese medicine composition for being used to prevent cad pig of the present invention, the characteristic of each component is as follows：
Radix Astragali is warm-natured, sweet in flavor.Returns spleen, lung channel.With tonifying Qi and lifting yang, invigorating qi for consolidating superficies, promoting pus discharge and tissue regeneration, inducing diuresis for removing edema work(
Effect.Veterinary clinic effect be mainly shown as Immune-enhancing effect, promote hematopoiesis, liver protection shield kidney, it is anti-oxidant the effects that.
Radix Angelicae Sinensis is warm-natured, sweet in flavor.Return liver, the heart, the spleen channel.Have the function of to enrich blood, invigorate blood circulation, relieve pain, moisturize laxation etc..Radix Angelicae Sinensis can promote
Into the hematopoiesis function of body, antithrombotic, reducing blood lipid, the dual regulation to uteri excitation and inhibition, liver protection shield kidney and adjust immune
Function etc..
Radix Codonopsis is warm-natured, sweet in flavor.Returns spleen, lung channel.Have effects that invigorating the lung and benefiting vital QI, invigorating the spleen promote the production of body fluid.Clinical main function performance
For there is adjustment effect to spleen, stomach function, liver, strengthen immunity, resisting stress and antioxidation are protected.
Honeysuckle is cold in nature, sweet in flavor.Return lung, the heart, stomach.There are heat-clearing solution, expelling wind and cold pathogens.Cure mainly warm disease heating,
Anemofrigid cold, cough with lung heat, abscess of throat etc..Clinical signs go out the works such as good antiviral, antibacterial and toxin, antipyretic and anti-inflammatory
With.
The coptis is cold in nature, bitter.The thoughts of returning home, liver, stomach, large intestine channel.There is heat-clearing and damp-drying drug, purging intense heat and detonicating.It cures mainly damp and hot
All diseases, heart-fire hyperactivity, sore Huang pyogenic infections etc..Clinic is usually used in damp-heat dysentery, knowledge swelling and pain, aphthae etc..
Rhizoma atractylodis are warm-natured, acrid flavour, hardship.Returns spleen, stomach, Liver Channel.There is invigorating the spleen to dry, expelling wind and clearing away cold, improving eyesight.It cures mainly wet
Hinder the diseases such as taste, abdominal fullness and distention, diarrhea oedema.It is clinical manifestations are liver protection, antiulcer, antibacterial, Li Shui, hypoglycemic, anti-swollen
The effects that knurl and adjustment gastrointestinal motility.
Rhizoma Atractylodis Macrocephalae is warm-natured, sweet in flavor, bitter.Returns spleen, stomach.Have effects that invigorate the spleen and benefit qi, eliminate dampness and have diuretic effect, strengthening exterior and reducing sweat.It cures mainly
Splenasthenic diarrhea, oedema, spontaneous perspiration and fetal irritability etc..
Cimicifugae foetidae cold nature, acrid flavour, micro-sweet.Return lung, spleen, stomach, large intestine channel.With deliver promoting eruption, it is clearing heat and detoxicating, rise lift yang-energy
The effect of.Cure mainly beans rash, sore swollen toxin, rush down prolapse of the anus for a long time.There are clinic the pharmacology such as antibacterial, antiviral, anti-inflammatory, antipyretic, analgesia to make
With.
Radix bupleuri cold nature, bitter.Return liver, gallbladder channel.Have effects that deliver and bring down a fever, soothing liver-qi stagnation, rise and lift yang-energy.It cures mainly cold
Hot contact, incoordination between the liver and the spleen, rush down prolapse of the anus for a long time, the prolapse of uterus.It is clinically micro- with antipyretic cooling, anti-inflammatory, calm, analgesia, disease-resistant original
The pharmacological actions such as biology and Immune-enhancing effect.
Poria cocos is mild-natured, sweet in flavor, light.The thoughts of returning home, lung, spleen, kidney channel.There is clearing damp and promoting diuresis, invigorating the spleen, antitoxic heart-soothing and sedative.It is main
Harness the river swollen oliguria, loose stool diarrhea, have no peace of mind.Clinical effect is mainly shown as Li Shui, tranquilizing the mind, anti-inflammatory, antibacterial, antitumor, guarantor
The effects that liver and strengthen immunity.
Green peel is warm-natured, acrid flavour, hardship.Return liver, courage, stomach.With the effect of soothing the liver relieving stagnant Qi, dissipating bindization is stagnant, while also one
Fixed sweating, cold dispelling effect.Cure mainly the cards such as distending pain in the chest and hypochondrium, hernia, newborn core, acute mastitis, having indigestion abdominal pain.
Dried orange peel is warm-natured, acrid flavour, hardship.Returns spleen, lung channel.There is regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm.Cure mainly chest gastral cavity turgor,
Deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.
Hawthorn slightly warm in nature, it is sour, sweet.Returns spleen, stomach, Liver Channel.With promoting digestion and removing indigestion, stomach invigorating, promoting the circulation of qi, promoting blood circulation to remove blood stasis work(
Effect.Cure mainly meat stagnation, diarrhea dysentery abdominal pain, stasis blocking chest and abdomen pain etc..
Malt is mild-natured, sweet in flavor.Returns spleen, stomach, Liver Channel.There is reinforcing spleen to promote digestion, delaactation dissipate-swelling.Clinic is usually used in getting ill from overeating
The diseases such as stagnant, swollen breasts, epigastric pain, cold of insufficiency type rush down dysentery.
Medicated Leaven is warm-natured, sweet in flavor, pungent.Returns spleen, stomach.With food digesting stomach fortifying and the effect of middle antidiarrheal.Cure mainly having indigestion not
The diseases such as change, abdominal fullness and distention, nausea and vomiting, borborygmus diarrhea.
The Chinese medicine composition for being used to prevent cad pig of the present invention, there is strengthen immunity, rich in nutrition, stomach invigorating rush to digest,
By improving piglet disease-resistant power, adjustment piglet spleen and stomach function, to prevent piglet disease occurs for the effects that antiviral, antibacterial, resisting stress
Disease improves the speed of growth of sick and weak piglet, reduces the quantity of cad pig.
Preferably, it is described for preventing the Chinese medicine composition of cad pig, it is made of the component of following parts by weight：60 parts of Radix Astragali,
60 parts of Radix Angelicae Sinensis, 60 parts of Radix Codonopsis, 60 parts of honeysuckle, 60 parts of the coptis, 60 parts of rhizoma atractylodis, 40 parts of Rhizoma Atractylodis Macrocephalae, 30 parts of cimicifugae foetidae, 30 parts of radix bupleuri, Fu
30 parts of Siberian cocklebur, 25 parts of green peel, 25 parts of dried orange peel, 20 parts of hawthorn, 20 parts of malt, 20 parts of Medicated Leaven.
Technical solution is used by the Chinese medicine microecological preparation for being used to prevent cad pig of the present invention：
A kind of Chinese medicine microecological preparation for being used to prevent cad pig, it is mainly former by fermenting microbe and the Chinese medicine of following parts by weight
Material mixed fermentation is made：50~70 parts of Radix Astragali, 50~70 parts of Radix Angelicae Sinensis, 50~70 parts of Radix Codonopsis, 50~70 parts of honeysuckle, the coptis 50~
70 parts, 50~70 parts of rhizoma atractylodis, 30~40 parts of Rhizoma Atractylodis Macrocephalae, 30~40 parts of cimicifugae foetidae, 30~40 parts of radix bupleuri, 30~40 parts of Poria cocos, green peel 20
~30 parts, 20~30 parts of dried orange peel, 15~25 parts of hawthorn, 15~25 parts of malt, 15~25 parts of Medicated Leaven.
The present invention for preventing the Chinese medicine microecological preparation of cad pig, the Chinese medicine composition of use have strengthen immunity,
The effects that rich in nutrition, stomach invigorating promote digestion, antiviral, antibacterial and resisting stress, by improving porkling premunition, adjustment porkling taste
Function occurs disease to prevent porkling, improves the speed of growth of sick and weak porkling, reduce the quantity of cad pig；To the Chinese medicine group of use
It closes object and carries out beneficial microbe fermentation, improve the function and effect of drug, reduce dosage, improve the palatability of feed；Through micro-
Containing a large amount of beneficial bacterium and its metabolite in Chinese medicine microecological preparation after biofermentation, it is extensive to be conducive to porkling intestinal flora
Multiple or holding balance, improves the ability that porkling enteron aisle digests and assimilates nutriment.The present invention is used to prevent the micro- life of Chinese medicine of cad pig
State preparation reduces the new city of cad pig, improves the production performance of weaned piglets by the effect of more than several respects.
Preferably, it is above-mentioned for preventing the Chinese medicine microecological preparation of cad pig, by fermenting microbe and following parts by weight
Medicine raw material mixed fermentation is made：It is 60 parts of Radix Astragali, 60 parts of Radix Angelicae Sinensis, 60 parts of Radix Codonopsis, 60 parts of honeysuckle, 60 parts of the coptis, 60 parts of rhizoma atractylodis, white
40 parts of art, 30 parts of cimicifugae foetidae, 30 parts of radix bupleuri, 30 parts of Poria cocos, 25 parts of green peel, 25 parts of dried orange peel, 20 parts of hawthorn, 20 parts of malt, Medicated Leaven
20 parts.
The fermenting microbe is by lactobacillus plantarum strain, enterococcus faecium strain, S. cervisiae strain, bacillus subtilis
Strain and Bacillus licheniformis strain composition.The fermenting microbe has the property that：
Lactobacillus plantarum, enterococcus faecium：Anaerobic type bacterium can generate organic acid in metabolic process, reduce gastrointestinal tract soda acid
Degree, promotes the generation of digestive ferment and improves the activity of enzyme, meanwhile, acidic environment can inhibit growth of pathogenic bacteria to breed；Fermenting microbe
In containing a large amount of enzyme, the degradation of plant medicine cell wall can be promoted, improve the dissolution rate of active ingredient.
S. cervisiae：Belong to facultative anaerobic bacteria, abundant enzyme can be generated in fermentation process, promote plant medicine thin
The degradation of cell wall improves the dissolution rate of active ingredient, simultaneously, moreover it is possible to improve the flavor of tunning, improve the palatability of Chinese medicine.
Bacillus subtilis, bacillus licheniformis：Aerobic bacteria can cause enteron aisle anaerobism by the oxygen consumed in enteron aisle
Environment is conducive to the growth and breeding of intestinal beneficial anaerobic bacteria flora such as Bifidobacterium, lactic acid bacteria etc., maintains intestinal flora balance；Together
When, growth and breeding generates a large amount of cellulase, amylase etc. and is conducive to improve digestion suction of the animal to nutriment in the process
Receive function；Other metabolites such as bacteriocin can inhibit the growth and breeding of the harmful bacterias such as Escherichia coli；To animal intestinal tract development and
Enteron aisle local immunity has facilitation.
The lactobacillus plantarum strain is lactobacillus plantarum bacterium solution, and enterococcus faecium strain is enterococcus faecium bacterium solution, ferment of making wine
Female bacterium strain be S. cervisiae bacterium solution, Bacillus subtilis strain be bacillus subtilis bacterium powder, Bacillus licheniformis strain
For Bacillus licheniformis powder.The dosage of the fermenting microbe is：The Radix Astragali of every 50~70g, which corresponds to, adds in lactobacillus plantarum strain
100~120mL, 100~120mL of enterococcus faecium strain, 100~120mL of S. cervisiae strain, Bacillus subtilis strain 10
~20g, 5~10g of Bacillus licheniformis strain.
Preferably, the dosage of the fermenting microbe is：Radix Astragali per 60g, which corresponds to, adds in lactobacillus plantarum strain 100mL, dung
Enterococcal species 100mL, S. cervisiae strain 120mL, Bacillus subtilis strain 15g, Bacillus licheniformis strain 5g.
The viable count of the lactobacillus plantarum strain is (1.0~10.0) × 108CFU/mL, the enterococcus faecium strain
Viable count is (5.0~10.0) × 108CFU/mL, the viable count of the S. cervisiae strain is (1.0~2.0) × 109CFU/
ML, the viable count of the Bacillus subtilis strain is (1.0~2.0) × 1011CFU/g, the Bacillus licheniformis strain
Viable count is (1.0~2.0) × 1011CFU/g。
Preferably, the viable count of the lactobacillus plantarum strain is 5.0 × 108CFU/mL, the enterococcus faecium strain
Viable count is 1.0 × 109CFU/mL, the viable count of the S. cervisiae strain is 1.5 × 109CFU/mL, the withered grass gemma
The viable count of bacillus species is 1.5 × 1011CFU/g, the viable count of the Bacillus licheniformis strain is 1.0 × 1011CFU/g。
The present invention for prevent cad pig the preparation method of Chinese medicine microecological preparation used by technical solution be：
A kind of preparation method of the above-mentioned Chinese medicine microecological preparation for being used to prevent cad pig, the Chinese medicine material including taking formula ratio
Powder and fermenting microbe mixing, in 25~35 DEG C of sealed fermentings 7~30 days.
The present invention for preventing the preparation method of the Chinese medicine microecological preparation of cad pig, it is at low cost, simple for process, convenient for pushing away
Wide application.
Preferably, the sealed fermenting is in 28 DEG C of sealed fermentings 15 days.
Preferably, the Chinese medicine material powder crosses 60~120 mesh sieve before use.
Application used technology of the Chinese medicine microecological preparation as feed addictive for being used to prevent cad pig of the present invention
Scheme is：
A kind of above-mentioned application of the Chinese medicine microecological preparation as feed addictive for being used to prevent cad pig.
It is above-mentioned for preventing application of the Chinese medicine microecological preparation as feed addictive of cad pig, Chinese medicine in every 1 ton of feed
The additive amount of probiotics is 3kg.When preventing cad pig, the feed of 7 days addition Chinese medicine microecological preparations is used in conjunction, deactivates 7 days,
Then the feed of 7 days addition Chinese medicine microecological preparations is used in conjunction again；When treating cad pig, 20 days addition Traditional Chinese drug microecologies are used in conjunction
The feed of preparation.
Specific embodiment
Technical scheme of the present invention is further described below in conjunction with specific embodiment.
Lactobacillus plantarum strain employed in specific embodiment is lactobacillus plantarum bacterium solution, and enterococcus faecium strain is dung
Enterococcus bacterium solution, S. cervisiae strain are S. cervisiae bacterium solution, and Bacillus subtilis strain is bacillus subtilis bacterium powder,
Bacillus licheniformis strain is Bacillus licheniformis powder.
Embodiment 1
The Chinese medicine composition for being used to prevent cad pig of the present embodiment, is made of the component of following parts by weight：60 parts of Radix Astragali,
60 parts of Radix Angelicae Sinensis, 60 parts of Radix Codonopsis, 60 parts of honeysuckle, 60 parts of the coptis, 60 parts of rhizoma atractylodis, 40 parts of Rhizoma Atractylodis Macrocephalae, 30 parts of cimicifugae foetidae, 30 parts of radix bupleuri, Fu
30 parts of Siberian cocklebur, 25 parts of green peel, 25 parts of dried orange peel, 20 parts of hawthorn, 20 parts of malt, 20 parts of Medicated Leaven.
The present embodiment for preventing the Chinese medicine composition of cad pig when in use, each Chinese medicine that formula ratio is taken to sieve with 100 mesh sieve
It is used in incorporation feed after component mixing.When preventing cad pig, above-mentioned Chinese medicine composition 3kg is added in feed per ton, is used in conjunction 7
My god, it deactivates 7 days, then be used in conjunction 7 days；During for treating cad pig, above-mentioned Chinese medicine composition 3kg is added in feed per ton, is used in conjunction
20 days.
The Chinese medicine microecological preparation for being used to prevent cad pig of the present embodiment, by the Chinese traditional medicine composition of fermenting microbe and the present embodiment
Object mixed fermentation is made；The dosage of the fermenting microbe is：Radix Astragali per 60g, which corresponds to, adds in lactobacillus plantarum strain 100mL, dung
Enterococcal species 100mL, S. cervisiae strain 120mL, Bacillus subtilis strain 15g, Bacillus licheniformis strain 5g；Institute
The viable count of lactobacillus plantarum strain used is 5.0 × 108CFU/mL, the viable count of enterococcus faecium strain for 1.0 ×
109CFU/mL, the viable count of S. cervisiae strain is 1.5 × 109CFU/mL, the viable count of Bacillus subtilis strain is 1.5
×1011CFU/g, the viable count of Bacillus licheniformis strain is 1.0 × 1011CFU/g。
The preparation method for being used to prevent the Chinese medicine microecological preparation of cad pig of the present embodiment, includes the following steps：In each
Medicine component crushes, sieves with 100 mesh sieve to obtain each Chinese medicine material powder respectively, takes each Chinese medicine material powder and fermenting microbe of formula ratio
Mixed, at 28 DEG C sealed fermenting 15 days to get.
It when being used as feed addictive for preventing the Chinese medicine microecological preparation of cad pig of the present embodiment, is added in feed per ton
Compound material is made in 3kg Chinese medicine microecological preparations.During for preventing cad pig, 7 days compound materials are used in conjunction, deactivating 7 days, then are used in conjunction 7 days again
Close material.During for treating cad pig, 20 days compound materials are used in conjunction.
Embodiment 2
The Chinese medicine composition for being used to prevent cad pig of the present embodiment, is made of the component of following parts by weight：50 parts of Radix Astragali,
70 parts of Radix Angelicae Sinensis, 70 parts of Radix Codonopsis, 50 parts of honeysuckle, 50 parts of the coptis, 70 parts of rhizoma atractylodis, 30 parts of Rhizoma Atractylodis Macrocephalae, 40 parts of cimicifugae foetidae, 35 parts of radix bupleuri, Fu
30 parts of Siberian cocklebur, 20 parts of green peel, 30 parts of dried orange peel, 15 parts of hawthorn, 25 parts of malt, 25 parts of Medicated Leaven.
The Chinese medicine microecological preparation for being used to prevent cad pig of the present embodiment, by the Chinese traditional medicine composition of fermenting microbe and the present embodiment
Object mixed fermentation is made；The dosage of the fermenting microbe is：Radix Astragali per 50g, which corresponds to, adds in lactobacillus plantarum strain 110mL, dung
Enterococcal species 120mL, S. cervisiae strain 100mL, Bacillus subtilis strain 20g, Bacillus licheniformis strain 10g；
The viable count of used lactobacillus plantarum strain is 1.0 × 109CFU/mL, the viable count of enterococcus faecium strain for 5.0 ×
108CFU/mL, the viable count of S. cervisiae strain is 2.0 × 109CFU/mL, the viable count of Bacillus subtilis strain is 2.0
×1011CFU/g, the viable count of Bacillus licheniformis strain is 2.0 × 1011CFU/g。
The preparation method for being used to prevent the Chinese medicine microecological preparation of cad pig of the present embodiment, includes the following steps：In each
Medicine component crushes respectively, 120 mesh excessively sieve to obtain each Chinese medicine material powder, takes each Chinese medicine material powder and fermenting microbe of formula ratio
Mixed, at 35 DEG C sealed fermenting 7 days to get.
When being used to prevent cad pig for preventing the Chinese medicine microecological preparation of cad pig of the present embodiment, adds in feed per ton
Compound material is made in 3kg Chinese medicine microecological preparations.During for preventing cad pig, 7 days compound materials are used in conjunction, being discontinued 7 days, then are used in conjunction 7 days again
Close material.During for treating cad pig, 20 days compound materials are used in conjunction.
Embodiment 3
The Chinese medicine composition for being used to prevent cad pig of the present embodiment, is made of the component of following parts by weight：70 parts of Radix Astragali,
50 parts of Radix Angelicae Sinensis, 50 parts of Radix Codonopsis, 70 parts of honeysuckle, 70 parts of the coptis, 50 parts of rhizoma atractylodis, 35 parts of Rhizoma Atractylodis Macrocephalae, 35 parts of cimicifugae foetidae, 40 parts of radix bupleuri, Fu
40 parts of Siberian cocklebur, 30 parts of green peel, 20 parts of dried orange peel, 25 parts of hawthorn, 15 parts of malt, 25 parts of Medicated Leaven.
The Chinese medicine microecological preparation for being used to prevent cad pig of the present embodiment, by the Chinese traditional medicine composition of fermenting microbe and the present embodiment
Object mixed fermentation is made；The dosage of the fermenting microbe is：Radix Astragali per 70g, which corresponds to, adds in lactobacillus plantarum strain 120mL, dung
Enterococcal species 110mL, S. cervisiae strain 110mL, Bacillus subtilis strain 10g, Bacillus licheniformis strain 10g；
The viable count of used lactobacillus plantarum strain is 1.0 × 108CFU/mL, the viable count of enterococcus faecium strain for 1.0 ×
109CFU/mL, the viable count of S. cervisiae strain is 1.0 × 109CFU/mL, the viable count of Bacillus subtilis strain is 1.0
×1011CFU/g, the viable count of Bacillus licheniformis strain is 1.0 × 1011CFU/g。
The preparation method for being used to prevent the Chinese medicine microecological preparation of cad pig of the present embodiment, includes the following steps：In each
Medicine component crushes respectively, 60 mesh excessively sieve to obtain each Chinese medicine material powder, takes each Chinese medicine material powder and fermenting microbe of formula ratio
Mixed, at 25 DEG C sealed fermenting 30 days to get.
It when being used as feed addictive for preventing the Chinese medicine microecological preparation of cad pig of the present embodiment, is added in feed per ton
Compound material is made in 3kg Chinese medicine microecological preparations.During for preventing cad pig, 7 days compound materials are used in conjunction, deactivating 7 days, then are used in conjunction 7 days again
Close material.During for treating cad pig, 20 days compound materials are used in conjunction.
Embodiment 4
The Chinese medicine composition for being used to prevent cad pig of the present embodiment, is made of the component of following parts by weight：50 parts of Radix Astragali,
50 parts of Radix Angelicae Sinensis, 50 parts of Radix Codonopsis, 70 parts of honeysuckle, 70 parts of the coptis, 50 parts of rhizoma atractylodis, 30 parts of Rhizoma Atractylodis Macrocephalae, 40 parts of cimicifugae foetidae, 40 parts of radix bupleuri, Fu
30 parts of Siberian cocklebur, 30 parts of green peel, 30 parts of dried orange peel, 20 parts of hawthorn, 20 parts of malt, 15 parts of Medicated Leaven.
The Chinese medicine microecological preparation for being used to prevent cad pig of the present embodiment, by the Chinese traditional medicine composition of fermenting microbe and the present embodiment
Object mixed fermentation is made；The dosage of the fermenting microbe is：Radix Astragali per 50g, which corresponds to, adds in lactobacillus plantarum strain 100mL, dung
Enterococcal species 120mL, S. cervisiae strain 110mL, Bacillus subtilis strain 15g, Bacillus licheniformis strain 8g；Institute
The viable count of lactobacillus plantarum strain used is 3.0 × 108CFU/mL, the viable count of enterococcus faecium strain for 8.0 ×
108CFU/mL, the viable count of S. cervisiae strain is 2.0 × 109CFU/mL, the viable count of Bacillus subtilis strain is 1.5
×1011CFU/g, the viable count of Bacillus licheniformis strain is 1.5 × 1011CFU/g。
The preparation method for being used to prevent the Chinese medicine microecological preparation of cad pig of the present embodiment, includes the following steps：In each
Medicine component crushes respectively, 80 mesh excessively sieve to obtain each Chinese medicine material powder, takes each Chinese medicine material powder and fermenting microbe of formula ratio
Mixed, at 32 DEG C sealed fermenting 20 days to get.
It when being used as feed addictive for preventing the Chinese medicine microecological preparation of cad pig of the present embodiment, is added in feed per ton
Compound material is made in 3kg Chinese medicine microecological preparations.During for preventing cad pig, 7 days compound materials are used in conjunction, deactivating 7 days, then are used in conjunction 7 days again
Close material.During for treating cad pig, 20 days compound materials are used in conjunction.
Embodiment 5
The Chinese medicine composition for being used to prevent cad pig of the present embodiment, is made of the component of following parts by weight：70 parts of Radix Astragali,
70 parts of Radix Angelicae Sinensis, 70 parts of Radix Codonopsis, 60 parts of honeysuckle, 60 parts of the coptis, 70 parts of rhizoma atractylodis, 40 parts of Rhizoma Atractylodis Macrocephalae, 35 parts of cimicifugae foetidae, 35 parts of radix bupleuri, Fu
40 parts of Siberian cocklebur, 20 parts of green peel, 20 parts of dried orange peel, 25 parts of hawthorn, 25 parts of malt, 15 parts of Medicated Leaven.
The present embodiment is used to prevent the Chinese medicine microecological preparation of cad pig, by fermenting microbe and the Chinese medicine composition of the present embodiment
Mixed fermentation is made；The dosage of the fermenting microbe is：Radix Astragali per 70g, which corresponds to, adds in lactobacillus plantarum strain 120mL, dung intestines
Coccus strain 100mL, S. cervisiae strain 120mL, Bacillus subtilis strain 20g, Bacillus licheniformis strain 5g；It is adopted
The viable count of lactobacillus plantarum strain is 8.0 × 108CFU/mL, the viable count of enterococcus faecium strain is 1.0 × 109CFU/
ML, the viable count of S. cervisiae strain is 1.5 × 109CFU/mL, the viable count of Bacillus subtilis strain for 2.0 ×
1011CFU/g, the viable count of Bacillus licheniformis strain is 1.0 × 1011CFU/g。
The preparation method for being used to prevent the probiotics of cad pig of the present embodiment, includes the following steps：By each Chinese medicine group
Divide and crush respectively, sieve with 100 mesh sieve to obtain each Chinese medicine material powder, each Chinese medicine material powder and fermenting microbe for taking formula ratio carry out
Mixing, at 30 DEG C sealed fermenting 10 days to get.
It when being used as feed addictive for preventing the Chinese medicine microecological preparation of cad pig of the present embodiment, is added in feed per ton
Compound material is made in 3kg Chinese medicine microecological preparations.During for preventing cad pig, 7 days compound materials are used in conjunction, deactivating 7 days, then are used in conjunction 7 days again
Close material.During for treating cad pig, 20 days compound materials are used in conjunction.
Experimental example 1
This experimental example investigate Examples 1 to 5 for prevent the Chinese medicine microecological preparation of cad pig and embodiment 1 for preventing
Control function and effect of the Chinese medicine composition of cad pig in quality cad pig, weak pig.
1) experiment material
Experiment reagent：Examples 1 to 5 for prevent the Chinese medicine microecological preparation of cad pig, embodiment 1 for preventing deadlock
The Chinese medicine composition of pig；
Experimental animal：Diarrhea, smoothing filter operator occur during delivery room, the 33 age in days child care without serious conditions are weak after treatment
Piglet.Pig integral status：It is listless, feed intake is relatively low, hair slightly disorderly, it is slow-growing.Experimental animal is by Guizhou Province Danzhai
County pig farm provides.
2) experimental method
Single factor test completely randomized design is taken in experiment, sets 7 groups, every group of 30 piglets altogether.Wherein experimental group 1~5 is distinguished
Feed the feed of the Chinese medicine microecological preparation of incorporation Examples 1 to 5；Experimental group 6 feeds the Chinese medicine composition of incorporation embodiment 1
Feed, group 7 are blank group, do not feed any drug.Experimental period is 20 days.
The feeding method of Examples 1 to 5 Chinese medicine microecological preparation：The Chinese medicine of corresponding embodiment is mixed in feed per ton addition
Probiotics 3kg is used in conjunction 20 days.
The feeding method of the Chinese medicine composition of embodiment 1：The Chinese medicine composition of embodiment 1 is mixed in feed per ton
3kg,；It is used in conjunction 20 days.
Clinical therapeutic efficacy is shown in Table 1.
After 1 each group medication of table to child care sick and weak weaned piglets effect
Clinical effectiveness：As shown in Table 1, the average end of group 1~6 be respectively increased 12.26% than 7 (blank groups) of group again,
11.72%th, 10.56%, 10.97%, 10.69%, 4.22%, average total feed intake has been respectively increased 9.37%, 11.90%,
11.06%th, 10.50%, 9.84%, 1.41%, average total augment weight has been respectively increased 29.24%, 28.36%, 26.46%,
27.63%th, 26.02%, 9.94%, feedstuff-meat ratio is below blank group, tests whole 6 dead 1 of pig of experiment of group, 7 experiment of group
Dead 3 of pig, other experimental groups are without injures and deaths.The result shows that Chinese medicine composition of the invention, Chinese medicine microecological preparation are used for
When sick and weak piglet, prevention cad pig form, improve sick and weak weaned piglets, have obvious effects on, it is special for the Chinese medicine for being the present invention
Probiotics function and effect are notable.
Experimental example 2
This experimental example investigate Examples 1 to 5 for prevent the Chinese medicine microecological preparation of cad pig and embodiment 1 with it is anti-
Control function and effect of the Chinese medicine composition of cad pig when preventing weaned piglets and reducing.
1) experiment material
Experiment reagent：Examples 1 to 5 for prevent the Chinese medicine microecological preparation of cad pig and embodiment 1 for preventing
The Chinese medicine composition of cad pig；
Experimental animal：28 age in days weanling pigs, pig integral status is normal, but smoothing filter operator, blue otopathy, branch in pig farm
Pneumonias and colibacillosis are higher in child care stage incidence, cause the death and culling rate that the child care stage is higher.Experimental animal by
Henan Province Huaiyang County pig farm provides.
2) experimental method
Single factor test completely randomized design is taken in experiment, sets 7 groups, every group of 30 piglets altogether.Wherein experimental group 1~5 is fed
The feed for being used to treat the Chinese medicine microecological preparation of cad pig of incorporation Examples 1 to 5, experimental group 6 feed the use of incorporation embodiment 1
In the feed of the Chinese medicine composition for the treatment of cad pig；Group 7 is blank group, does not feed any drug.Experiment periods are 20 days.
The feeding method for being used to prevent the Chinese medicine microecological preparation of cad pig of Examples 1 to 5：Feed addition per ton is corresponding real
The Chinese medicine microecological preparation 3kg of example is applied, is used in conjunction 7 days, is discontinued 7 days, then be used in conjunction 7 days.
The feeding method for being used to prevent the Chinese medicine composition of cad pig of embodiment 1：It is mixed in embodiment 1 in feed per ton
Drug composition 3kg is used in conjunction 7 days, is discontinued 7 days, then be used in conjunction 7 days.
Clinical prophylactic performance is shown in Table 2.
Production Performance of Weaning Pigs is influenced after 2 each group medication of table
Clinical effectiveness：As shown in Table 2, the average end of group 1~6 be respectively increased 15.40% than 7 (blank groups) of group again,
15.28%th, 14.36%, 12.89%, 14.29%, 3.19%, average total feed intake has been respectively increased 7.53%, 10.70%,
9.02%th, 9.42%, 9.91%, 2.68%, average total augment weight has been respectively increased 30.54%, 29.25%, 28.42%,
26.42%th, 28.18%, 7.19%, feedstuff-meat ratio is below blank group；The whole 6 experiment pig of group of experiment extremely washes in a pan 2,7 experiment of group
Pig extremely washes in a pan 3, other test groups are without injures and deaths.The result shows that Chinese medicine microecological preparation of the invention and Chinese medicine composition are used
Function and effect when preventing weaned piglets and reducing are apparent, and especially Chinese medicine microecological preparation function and effect of the invention are shown
It writes.
Claims (10)
1. a kind of Chinese medicine composition for being used to prevent cad pig, it is characterised in that：It is made of the component of following parts by weight：Radix Astragali 50~
70 parts, 50~70 parts of Radix Angelicae Sinensis, 50~70 parts of Radix Codonopsis, 50~70 parts of honeysuckle, 50~70 parts of the coptis, 50~70 parts of rhizoma atractylodis, Rhizoma Atractylodis Macrocephalae
30~40 parts, 30~40 parts of cimicifugae foetidae, 30~40 parts of radix bupleuri, 30~40 parts of Poria cocos, 20~30 parts of green peel, 20~30 parts of dried orange peel, mountain
15~25 parts of short, bristly hair or beard, 15~25 parts of malt, 15~25 parts of Medicated Leaven.
2. the Chinese medicine composition according to claim 1 for being used to prevent cad pig, it is characterised in that：By the group of following parts by weight
It is grouped as：60 parts of Radix Astragali, 60 parts of Radix Angelicae Sinensis, 60 parts of Radix Codonopsis, 60 parts of honeysuckle, 60 parts of the coptis, 60 parts of rhizoma atractylodis, 40 parts of Rhizoma Atractylodis Macrocephalae, cimicifugae foetidae
30 parts, 30 parts of radix bupleuri, 30 parts of Poria cocos, 25 parts of green peel, 25 parts of dried orange peel, 20 parts of hawthorn, 20 parts of malt, 20 parts of Medicated Leaven.
3. a kind of Chinese medicine microecological preparation for being used to prevent cad pig, it is characterised in that：Mainly by fermenting microbe and following parts by weight
Several Chinese medicine material mixed fermentations are made：50~70 parts of Radix Astragali, 50~70 parts of Radix Angelicae Sinensis, 50~70 parts of Radix Codonopsis, honeysuckle 50~70
Part, 50~70 parts of the coptis, 50~70 parts of rhizoma atractylodis, 30~40 parts of Rhizoma Atractylodis Macrocephalae, 30~40 parts of cimicifugae foetidae, 30~40 parts of radix bupleuri, Poria cocos 30~
40 parts, 20~30 parts of green peel, 20~30 parts of dried orange peel, 15~25 parts of hawthorn, 15~25 parts of malt, 15~25 parts of Medicated Leaven.
4. the Chinese medicine microecological preparation according to claim 3 for being used to prevent cad pig, it is characterised in that：The fermenting microbe
By lactobacillus plantarum strain, enterococcus faecium strain, S. cervisiae strain, Bacillus subtilis strain and Bacillus licheniformis
Kind composition.
5. the Chinese medicine microecological preparation according to claim 4 for being used to prevent cad pig, it is characterised in that：The fermenting microbe
Dosage be：The Radix Astragali of every 50~70g correspond to add in 100~120mL of lactobacillus plantarum strain, enterococcus faecium strain 100~
120mL, 100~120mL of S. cervisiae strain, 10~20g of Bacillus subtilis strain, Bacillus licheniformis strain 5~
10g。
6. the Chinese medicine microecological preparation according to claim 5 for being used to prevent cad pig, it is characterised in that：The plant breast bar
The viable count of bacterium strain is (1.0~10.0) × 108CFU/mL, the viable count of the enterococcus faecium strain is (5.0~10.0)
×108CFU/mL, the viable count of the S. cervisiae strain is (1.0~2.0) × 109CFU/mL, the bacillus subtilis
The viable count of strain is (1.0~2.0) × 1011CFU/g, the viable count of the Bacillus licheniformis strain for (1.0~2.0) ×
1011CFU/g。
7. a kind of preparation method of the Chinese medicine microecological preparation as claimed in claim 3 for being used to prevent cad pig, it is characterised in that：
Including taking the Chinese medicine material powder of formula ratio and fermenting microbe mixing, in 25~35 DEG C of sealed fermentings 7~30 days.
8. the preparation method of the Chinese medicine microecological preparation according to claim 7 for being used to prevent cad pig, it is characterised in that：Institute
It is in 28 DEG C of sealed fermentings 15 days to state sealed fermenting.
9. a kind of application of Chinese medicine microecological preparation as feed addictive as claimed in claim 3 for being used to prevent cad pig.
10. it is according to claim 9 for preventing application of the Chinese medicine microecological preparation as feed addictive of cad pig,
It is characterized in that：The additive amount of Chinese medicine microecological preparation is 3kg in every 1 ton of feed.
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| CN109566858A (en) * | 2019-01-23 | 2019-04-05 | 于长江 | A kind of poultry traditional Chinese medicine for livestock compound bio fermented feed and preparation method thereof |
| CN112741869A (en) * | 2021-03-18 | 2021-05-04 | 河南省帝一方生物制药有限公司 | Fermented traditional Chinese medicine preparation for strengthening body resistance and eliminating pathogenic factors of livestock and poultry and preparation method thereof |
| CN114504060A (en) * | 2022-03-31 | 2022-05-17 | 四川省旺达饲料有限公司 | Traditional Chinese medicine mixed pig feed and preparation method thereof |
| CN114848763A (en) * | 2022-03-25 | 2022-08-05 | 河南牧业经济学院 | Traditional Chinese medicine composition for sows in gestation period and/or lactation period, fermented traditional Chinese medicine preparation and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109010662A (en) * | 2018-10-30 | 2018-12-18 | 河南后羿实业集团有限公司 | A kind of rush digestion growth promotion probiotics and preparation method thereof |
| CN109566858A (en) * | 2019-01-23 | 2019-04-05 | 于长江 | A kind of poultry traditional Chinese medicine for livestock compound bio fermented feed and preparation method thereof |
| CN112741869A (en) * | 2021-03-18 | 2021-05-04 | 河南省帝一方生物制药有限公司 | Fermented traditional Chinese medicine preparation for strengthening body resistance and eliminating pathogenic factors of livestock and poultry and preparation method thereof |
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Application publication date: 20180710 |