CN105767587A - Traditional Chinese medicine microecological preparation for improving laying hen performance and preparation method of traditional Chinese medicine microecological preparation for improving laying hen performance - Google Patents
Traditional Chinese medicine microecological preparation for improving laying hen performance and preparation method of traditional Chinese medicine microecological preparation for improving laying hen performance Download PDFInfo
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/169—Plantarum
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a traditional Chinese medicine microecological preparation for improving laying hen performance and a preparation method of the traditional Chinese medicine microecological preparation for improving the laying hen performance. The traditional Chinese medicine microecological preparation is prepared from fermentative strains and raw materials by means of mixed fermentation, wherein the raw materials include, by weight, 15-20 parts of Radix Astragali, 7-10 parts of Herba Epimedii, 50-60 parts of Folium Artemisiae Argyi, 8-12 parts of Fructus Jujubae and 7-10 parts of yeast cell wall polysaccharide, and as for every 15-20 g of Radix Astragali, 10-15 mL of bacillus subtilis, 3-5 mL of bacillus licheniformis, 5-10 mL of lactobacillus plantarum and 20-25 mL of enterococcus faecium are added correspondingly. The traditional Chinese medicine microecological preparation has the advantages that the traditional Chinese medicine microecological preparation is high in drug utilization ratio and remarkable in efficacy and solves the problems of bacterial drug resistance, drug residue, contamination of mycotoxins to feed and the like, laying hen immunity and intestinal tract digestion-absorption functions are enhanced, egg laying rate of laying hens is increased while egg quality is improved, and elimination time is prolonged, so that the laying hen performance is improved on the whole.
Description
Technical field
The invention belongs to traditional Chinese medicine for livestock microbial ecological agent technical field, be specifically related to a kind of Chinese medicine microecological preparation for improving production performance of layer chicken, the preparation method also relating to a kind of Chinese medicine microecological preparation for improving production performance of layer chicken.
Background technology
Egg production is to weigh the important indicator of performance in layers, is also the key affecting breeding layer chicken economic benefit.Egg Production of Laying Hens enters middle and late stage, on the one hand, the Intervention of its internal secretion reproductive hormone day by day fails, various reproductive hormones such as follicule-stimulating hormone (FSH), interstitialcellstimulating hormone (ICSH) isoconcentration are gradually lowered, and follicular development has the prolactin level of direct repression constantly rise, causing that in egg fowl ovary, the growth promoter of follicle is suppressed gradually, ovulation amount reduces, and laying rate declines;On the other hand, the production of high intensity makes laying hen be in stress sensitive state, and the immunologic function of body, function of intestinal canal etc. reduce, and the sensitivity of pathogenic microorganism is improved, and sickness rate and death rate raise.
The method in the past solving the problems such as egg laying performance decline, sickness rate rising mainly adds antibiotic in feedstuff and drinking-water, but the interpolation of long-term, high-dose result in a lot of problem, as the generation of Resistant strain, egg drug residue exceed standard, cause serious environmental pollution and threaten the health of people.Chinese herbal medicine replaces antibiotic can effectively reduce drug residue problem in animal feeding process.
nullIn prior art,CN103704515B discloses a kind of feed additive for improving Layer Production Performance,It is made up of the raw medicinal material of following parts by weight: Herba Epimedii 10-20 part、Radix Morindae Officinalis 10-20 part、Herba Leonuri 15-25 part、Fructus Ligustri Lucidi 10-20 part、Flos Rosae Chinensis 10-20 part、Fructus Psoraleae 15-25 part、Radix Codonopsis 10-20 part、Radix Rehmanniae Preparata 15-20 part、Radix Angelicae Sinensis 10-20 part、Fructus Jujubae 10-20 part、Herba Cistanches 15-20 part、Semen Cuscutae 10-15 part、Fructus Lycii 10-20 part、Rhizoma Atractylodis Macrocephalae 10-20 part、Radix Astragali 10-20 part、Folium Artemisiae Argyi 10-20 part、Radix Glycyrrhizae 10-20 part、DAWANHUA 10-20 part、Swing skin ginseng 15-25 part、Stigma Croci 10-15 part、Fructus Aurantii 15-20 part and Herba Oryzae Reproductii 10-20 part;Its preparation method is to adopt twice water to carry rear merging filtrate, and concentration gets dry extract, and is crushed to less than 30 μm, it is thus achieved that feed additive powder.This feed additive improves Layer Production Performance to a certain extent, has pure natural, has no drug resistance, the advantage that toxic and side effects is little.
But, due to the restriction of the digestive system of laying hen, traditional Chinese herbal and crude drugs preparations exists that action effect is slow, utilization rate is low, the unconspicuous problem of medicinal effects;And the appearance of biofermentation traditional Chinese medicine technology, make the drug effect of Chinese herbal medicine be greatly improved, and show comparatively significantly effect gradually in prevention disease and raising production performance etc..
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine microecological preparation for improving production performance of layer chicken, absorbance is high, and medicinal effects is notable, it is possible to significantly improve the economic benefit of breeding layer chicken.
The preparation method that second purpose of the present invention is to provide a kind of Chinese medicine microecological preparation for improving production performance of layer chicken.
In order to realize object above, the technical solution adopted in the present invention is:
A kind of Chinese medicine microecological preparation for improving production performance of layer chicken, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 15~20 parts, Herba Epimedii 7~10 parts, Folium Artemisiae Argyi 50~60 parts, 8~12 parts of Fructus Jujubae, yeast cell wall polysaccharide 7~10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 15~20g adds Bacillus subtilis strain 10~15mL, Bacillus licheniformis strain 3~5mL, Lactobacillus plantarum strain 5~10mL, enterococcus faecalis strain 20~25mL.
Preferably, the described Chinese medicine microecological preparation for improving production performance of layer chicken, it is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 18 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 60 parts, 12 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 18g adds Bacillus subtilis strain 15mL, Bacillus licheniformis strain 3mL, Lactobacillus plantarum strain 5mL, enterococcus faecalis strain 25mL.
Described fermentation is solid fermentation.
The viable count of described Bacillus subtilis strain is (1.0~3.0) × 109CFU/mL, the viable count of Bacillus licheniformis strain is (1.0~3.0) × 109CFU/mL, the viable count of Lactobacillus plantarum strain is (1.0~5.0) × 108CFU/mL, the viable count of enterococcus faecalis strain is (1.0~5.0) × 108CFU/mL。
Preferably, the viable count of described Bacillus subtilis strain is 1.5 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 2.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 1.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 4.0 × 108CFU/mL。
Wherein, the component content (mass percent) of described yeast cell wall polysaccharide is: protein≤35%, beta glucan 20%~40%, total sugar >=40%, moisture≤9%.
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention, the characteristic of each raw material is as follows:
The Radix Astragali: warm in nature, sweet in the mouth;Return lung, spleen channel;There is tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, effect of promoting pus discharge and tissue regeneration strengthening.Modern pharmacological research shows, its Main Function composition is astragalus polysaccharides, flavone, saponin etc., and its Main Function has: strengthens normal heart and shrinks, and the heart of exhaustion is had cardiotonic, expands whole body peripheral vessel, improve microcirculation;Protect the liver and protect kidney, neutralize a toxin;Promote the growth of immune organ, improve the activity of immunocyte, improve the effect of vaccine immunity;Intestinal beneficial bacterium is had facilitation, improves intestinal microenvironment;Antiviral, it is possible to stimulate the generation of interferon, the pathogen such as escherichia coli are had inhibitory action.
Herba Epimedii: warm in nature, acrid in the mouth, sweet;Return liver, kidney channel;There is kidney invigorating and YANG supporting, expelling wind and removing dampness, effect of relieving cough and asthma.Modern pharmacological research shows, its Main Function composition is icariin, demethyl icariin etc., and its Main Function has: blood pressure lowering, improves microcirculation and hypoglycemic effect;Can promote and two-ways regulation immunologic function;Antibacterial, the antiinflammatory of energy, and inducement interferon, significantly inhibit effect to poliovirus;Promote bone growth, stop calcium loss, pre-preventing bone rarefaction;Still there are defying age, antioxidation, antineoplastic prospect.
Folium Artemisiae Argyi: warm in nature, bitter in the mouth, pungent;Return liver,spleen,kidney warp;There is warming the meridian for stopping bleeding, cold expelling regulating menstruation, antiabortive effect.Modern pharmacological research shows, its Main Function composition is volatile oil, has cineole, linalool etc., and its Main Function has: reduces capillary permeability, fibrinolysis, plays anastalsis;There is the effect of obvious antitussive, calmness and eliminating phlegm and relieving asthma;Staphylococcus aureus, beta hemolytic streptococcus and escherichia coli etc. are all killed or inhibitory action by antiallergic.
Fructus Jujubae: warm in nature, sweet in the mouth;Return spleen, stomach warp;There is invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, relax effect of the property of medicine.Modern study shows, its primary medicinal component is alkaloids, flavonoid, amino acids, organic acid and vitamin, can put on weight and muscular strength, protect the liver, antiallergic and sedation.
Yeast cell wall polysaccharide: the macromole carbohydrate polymer extracted from yeast cell wall, mainly has glucosan and mannan.Main Function has: the immunologic function of enhancing body, lymphocytic propagation in stimulating animal body, strengthens the action function of macrophage, natural killer cell;Promote the propagation of intestinal beneficial bacterium, regulate animal alimentary canal microecological balance, improve function of intestinal canal;Mycotoxin in feedstuff there is stronger adsorption;Prevention and adjuvant treatment of diseases, promote ill poultry rehabilitation, reduce antibiotic use.
Bacillus subtilis, Bacillus licheniformis: belong to aerobic-type antibacterial, can breed rapidly when aerobic, the oxygen consumed in environment causes anaerobic environment, and can produce to promote the beneficial bacteria factor of lactic acid bacteria, bifidobacterium growth, thus maintaining the superiority of the intrinsic bacterium of the intestinal such as lactic acid bacteria, bacillus bifidus, keep the balance of intestinal microenvironment;Sweat produces various enzyme, is conducive to fermentation substrate and the degraded of intestinal food, increases operation rate;Such as pathogenic microorganism is had inhibitory action to metabolite by subtilin, bacitracin;The generation of ammonia can be reduced, improve the environment of growth of animals or poultry.
Lactobacillus plantarum, enterococcus faecalis: belong to anaerobic type antibacterial, metabolic process produces organic acid and the digestive enzyme such as substantial amounts of acetic acid, propanoic acid, reducing gastrointestinal pH, contribute to activation and improve pepsic activity, sour environment can effectively suppress growth of pathogenic bacteria to breed;Escherichia coli, Salmonella etc. are had suppression or killing action by the lactein in metabolite;Improve intestinal microenvironment, stimulate the growth of intestinal immune tissue, improve intestinal immunity.
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention, the Radix Astragali selected by raw material, Fructus Jujubae etc. are mainly QI invigorating qi-restoratives, protect the liver the Chinese medicine protecting kidney class, with four kinds of probiotic bacterias, Chinese medicine composition medicated powder is carried out solid fermentation, first, can effectively degrade Chinese medicinal plant cell wall, it is beneficial to the release of effective ingredient, utilization rate and the drug effect of medicine can be improved, reduce dosage;Secondly, fermentation probiotic bacteria strain and laying hen intestinal autochthonous flora are respectively provided with growth promoting function by the Radix Astragali, it is possible to improve the quantity of probiotic bacteria in this preparation, and improve laying hen intestinal microenvironment, promote intestinal microbial population balance;Finally, probiotic bacteria produces the metabolites such as organic acid, bacteriocin and vitamin during the fermentation, has biologic activity widely, the raising of Layer Production Performance is had facilitation.
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention, adopts the Radix Astragali, Herba Epimedii, Folium Artemisiae Argyi, this 4 taste Chinese medicine of Fructus Jujubae to coordinate with yeast cell wall polysaccharide, utilizes fermented bacterium to make through solid fermentation.Side reuses Folium Artemisiae Argyi, warming the meridian for stopping bleeding, cold expelling regulating menstruation, antiabortive, improve eggshell, yolk color, improve egg size and also improve pouity dwelling place abnormal smells from the patient;The Radix Astragali, Fructus Jujubae invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind;Herba Epimedii and the same use of the Radix Astragali, synergism each other, tonifying Qi and lifting yang, expelling wind and removing dampness, hidroschesis consolidating superficial resistance.The Chinese medicine microecological preparation prepared through probiotics fermention after each taste Chinese medicine and yeast cell wall polysaccharide composite, from the aspect of medication, improves the effect of former Chinese medicine, extends its action function and the problem solving drug residue and drug resistance after fermentation;From the aspect of nutrition, yeast cell wall polysaccharide component can absorbing mycotoxin, improve feed quality;Applying effect aspect from laying hen itself, improve the immunity of body, improve the balance of function that intestinal digests and assimilates and flora, its integral production efficiency is improved.
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention, select 4 kinds and can improve blood circulation, slow down aging, improve the Chinese medicine of reproductive capability and immunocompetence, cooperation has feedstuff and takes off the polysaccharide of mould effect, utilize microbial solid fermentation technology Chinese herbal medicine, probiotic bacteria to be combined, make the Chinese medicine microecological preparation of a kind of fermented type.This Chinese medicine microecological preparation utilization ratio of drug is high, drug effect is notable, rapid-action, first solves the problem that Chinese traditional herbs action effect is slow, utilization rate is low;Secondly, it is possible to reduce antibiotic application, make bacterial drug resistance, drug residue and feedstuff are readily solved by problems such as mycotoxin contaminations;Finally, enhance immunity of layer chicken and intestinal digestive and absorptive functions so that it is body is in health status, and then improves the quality of laying rate of laying hen and egg, postpone the time of eliminating, reach on the whole to improve performance in layers, create the purpose of economic worth for breeding layer chicken industry.
The preparation method of a kind of above-mentioned Chinese medicine microecological preparation for improving production performance of layer chicken, after mixing including the raw material and fermented bacterium that take formula ratio, under 25~40 DEG C of conditions, sealed fermenting 7~30 days, to obtain final product.
Preferably, the preparation method of the described Chinese medicine microecological preparation for improving production performance of layer chicken, after mixing including the raw material and fermented bacterium that take formula ratio, under 32 DEG C of conditions, sealed fermenting 20 days, to obtain final product.
The Radix Astragali in described raw material, Herba Epimedii, Folium Artemisiae Argyi, Fructus Jujubae are pulverized in advance and cross 100~200 mesh sieves, obtain medicated powder standby.Gained medicated powder is mixed with yeast cell wall polysaccharide and fermented bacterium again and ferments.
Preferably, the Radix Astragali in described raw material, Herba Epimedii, Folium Artemisiae Argyi, Fructus Jujubae are pulverized in advance and cross 200 mesh sieves, obtain medicated powder standby.
Wherein, the component content (mass percent) of yeast cell wall polysaccharide used is: protein≤35%, beta glucan 20%~40%, total sugar >=40%, moisture≤9%.
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention, is Chinese medicine, yeast cell wall polysaccharide are made through solid fermentation after mixing with fermented bacterium;The method is easy and simple to handle, and without harmful substances such as three industrial wastes after fermentation, utilization rate is high, and feasibility is good, it is adaptable to large-scale industrial production, has good application value.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present invention is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;Treatment performance in layers reduce time, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the present invention is further illustrated.
In detailed description of the invention, the component content (mass percent) of yeast cell wall polysaccharide used is: protein≤35%, beta glucan 20%~40%, total sugar >=40%, moisture≤9%.
Embodiment 1
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 15 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 50 parts, 8 parts of Fructus Jujubae, yeast cell wall polysaccharide 7 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 15g adds Bacillus subtilis strain 10mL, Bacillus licheniformis strain 3mL, Lactobacillus plantarum strain 5mL, enterococcus faecalis strain 20mL.
Wherein, the viable count of described Bacillus subtilis strain is 1.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 3.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 1.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 5.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: crosses 100 mesh sieves after taking the former material pulverizing of Chinese medicine of formula ratio, obtains medicated powder;After being mixed homogeneously with yeast cell wall polysaccharide and fermented bacterium by gained medicated powder, under 25 DEG C of conditions, sealed fermenting 30 days, to obtain final product.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;Treatment performance in layers reduce time, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Embodiment 2
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 20 parts, Herba Epimedii 10 parts, Folium Artemisiae Argyi 60 parts, 12 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 20g adds Bacillus subtilis strain 15mL, Bacillus licheniformis strain 5mL, Lactobacillus plantarum strain 10mL, enterococcus faecalis strain 25mL.
Wherein, the viable count of described Bacillus subtilis strain is 3.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 1.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 5.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 1.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: crosses 120 mesh sieves after taking the former material pulverizing of Chinese medicine of formula ratio, obtains medicated powder;After being mixed homogeneously with yeast cell wall polysaccharide and fermented bacterium by gained medicated powder, under 40 DEG C of conditions, sealed fermenting 7 days, to obtain final product.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;Treatment performance in layers reduce time, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Embodiment 3
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 17 parts, Herba Epimedii 8 parts, Folium Artemisiae Argyi 55 parts, 10 parts of Fructus Jujubae, yeast cell wall polysaccharide 8 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 17g adds Bacillus subtilis strain 13mL, Bacillus licheniformis strain 4mL, Lactobacillus plantarum strain 7mL, enterococcus faecalis strain 23mL.
Wherein, the viable count of described Bacillus subtilis strain is 2.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 2.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 4.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 3.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: crosses 150 mesh sieves after taking the former material pulverizing of Chinese medicine of formula ratio, obtains medicated powder;After being mixed homogeneously with yeast cell wall polysaccharide and fermented bacterium by gained medicated powder, under 37 DEG C of conditions, sealed fermenting 15 days, to obtain final product.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;Treatment performance in layers reduce time, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Embodiment 4
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 18 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 60 parts, 12 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 18g adds Bacillus subtilis strain 15mL, Bacillus licheniformis strain 3mL, Lactobacillus plantarum strain 5mL, enterococcus faecalis strain 25mL.
Wherein, the viable count of described Bacillus subtilis strain is 1.5 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 2.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 1.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 4.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: crosses 200 mesh sieves after taking the former material pulverizing of Chinese medicine of formula ratio, obtains medicated powder;After being mixed homogeneously with yeast cell wall polysaccharide and fermented bacterium by gained medicated powder, under 32 DEG C of conditions, sealed fermenting 20 days, to obtain final product.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;During treatment, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Embodiment 5
The Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment, is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 15 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 60 parts, 10 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 15g adds Bacillus subtilis strain 10mL, Bacillus licheniformis strain 5mL, Lactobacillus plantarum strain 10mL, enterococcus faecalis strain 25mL.
Wherein, the viable count of described Bacillus subtilis strain is 1.0 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 1.5 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 3.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 2.0 × 108CFU/mL。
The preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: crosses 200 mesh sieves after taking the former material pulverizing of Chinese medicine of formula ratio, obtains medicated powder;After being mixed homogeneously with yeast cell wall polysaccharide and fermented bacterium by gained medicated powder, under 30 DEG C of conditions, sealed fermenting 25 days, to obtain final product.
The usage of the Chinese medicine microecological preparation for improving production performance of layer chicken of the present embodiment is: when prevention performance in layers reduces, feedstuff per ton adds this product 2000g, is used in conjunction 7~10 days every time, every 10~15 days repeated drug takings once;Treatment performance in layers reduce time, feedstuff per ton adds this product 4000g, within 7~10 days, is a course for the treatment of, each course for the treatment of 3 days, interval.
Comparative example
The Chinese medicine preparation of this comparative example is made up of the raw material of following parts by weight: the Radix Astragali 18 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 60 parts, 12 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;200 mesh sieves crossed by the former material of Chinese medicine after pulverizing, mix homogeneously and get final product.The same above-described embodiment of usage.
Experimental example
The Chinese medicine microecological preparation the improving production performance of layer chicken performance of preventing and treating in laying hen feeds that is used for of embodiment 1-5 gained is detected by this experimental example.
(1) in prevention laying rate reduction:
Within 2015, carry out contrast experiment in Hebi City laying hen field, Henan Province, 700 60 weeks laying hens of navigating are randomly divided into 7 groups, often group 100, organize the feedstuff of the 1-5 method feeding successively according to the embodiment 1-5 Chinese medicine microecological preparation containing embodiment 1-5, group 6 then feeding is containing the feedstuff of comparative example Chinese medicine preparation, and using method is identical with group 1-5's.Group 7 is blank group, the not any medicine of feeding.Recording the egg laying performance of laying hen after 1 week, continuously record 1 week, preventive effect is table 1 such as.
Table 1 is respectively organized preventive effect and is compared
(note: laying rate raising value is the laying rate absolute value with the difference of the laying rate of group 7 of group 1-6, egg size raising value is the average egg weight absolute value with the difference of group 7 average egg weights of group 1-6)
As it can be seen from table 1 compared with conventional Chinese drug-treated group and blank group, after taking the Chinese medicine microecological preparation of embodiment 1-5, the laying rate of laying hen does not improve in 5.28%-7.71% scope not etc., average egg production raising 6.48%;Egg size improves at 3.29-5.05g, and average egg weight improves 4.04g.Test result indicate that, the Chinese medicine microecological preparation of the present invention has remarkable result in prevention laying rate of laying hen reduction, egg laying performance decline.
Type testing example 1:2015 carries out contrast test in laying hen field, Neihuang County, Henan Province, 6000 65 weeks blue brown laying hens in sea are randomly divided into 2 groups, respectively test group and matched group, often group 3000, test group feeds the feedstuff of the Chinese medicine microecological preparation containing embodiment 3, and method method as described in Example 3 feeds;Matched group feeding Normal Goods feedstuff, feeding and management is scheduled for by field.The egg laying performance of laying hen is recorded, continuously record 1 week after 1 week.Result is as follows, the average egg production of test group and egg size respectively 83.26%, 65.21g, the average egg production of matched group and egg size respectively 72.68%, 61.63g.Compared with matched group, the average egg production of test group and egg size have been respectively increased 10.58%, 3.58g.
(2) in treatment performance in layers reduction:
Within 2015, in laying hen field, Neihuang County, Henan Province, the 48 blue brown laying hen sudden onset in week old seas, feed intake declines, and the mental status is deteriorated, laying rate decline 20%-30%, and eggshell is without color and luster, and broken egg, soft egg increases, and is the egg drop syndrome of chicken through Disease Diagnosis of Veterinary.Randomly selecting 700 sick chickens and be divided into 7 groups, often group 100, organize the feedstuff of the 1-5 method feeding successively according to the embodiment 1-5 Chinese medicine microecological preparation containing embodiment 1-5, group 6 then feeding is containing the feedstuff of comparative example Chinese medicine preparation, and using method is identical with group 1-5's.Group 7 is blank group, the not any medicine of feeding.Recording the egg laying performance of laying hen after 1 week, continuously record 1 week, therapeutic effect is table 2 such as.
The therapeutic effect that table 2 is respectively organized
(note: laying rate raising value, average egg weight raising value and residual egg rate decreasing value respectively organize the absolute value of the laying rate of 1-6, average egg weight and residual egg rate and the difference of the laying rate of group 7, average egg weight and residual egg rate)
From table 2 it can be seen that compared with conventional Chinese drug-treated group and blank group, after taking the Chinese medicine microecological preparation of embodiment 1-5, laying rate of laying hen does not improve in 17.71%-20.29% scope not etc., average egg production raising 19.03%;Egg size improves at 4.66-5.38g, and average egg weight improves 4.98g, and residual egg rate reduces at 3.71%-3.94%, average out to 3.84%.Result of the test shows, the Chinese medicine microecological preparation of the present invention has remarkable result in treatment Layer Production Performance decline.
Type testing example 2:2015 is in laying hen field, Shouguang county of Shandong Province, 35 week old are navigated laying hen sudden onset, feed intake declines, diarrhoea, indivedual chickens have cough with asthma symptom, and laying rate declines about 25%, egg size alleviates, eggshell is without color and luster, and broken egg, soft egg, abnormal-shape egg increase, and is reload suddenly to cause that the egg laying performance that stress cause declines through Disease Diagnosis of Veterinary.Adopting the Chinese medicine microecological preparation of embodiment 5, feedstuff per ton adds 4kg, is used in conjunction 4 days, and full group's laying hen disease disappears, and laying rate is recovered to premorbid, is about 87%, and egg size average out to 63.56g, residual egg rate is down to 2.3%.
Type testing example 3:2015 is in common chicken field, Taiqian County, Henan Province, 45 week old left and right chicken sudden onset, laying rate falls to approximately 40% from about 70%, full group's chicken spirit is depressed, through understanding the state of an illness, reason be mainly change in weather stress caused by, add feedstuff and caused chicken house to fall ill by mould contamination, the reason such as unclean of drinking water.Adopting the Chinese medicine microecological preparation of embodiment 4, feedstuff per ton adds 4kg, is used in conjunction 3 days, and full group's chicken spirit takes a turn for the better, and feed intake increases, and after 5 days, laying rate is recovered to premorbid, is about 70%, egg size average out to 50g.
Claims (8)
1. the Chinese medicine microecological preparation being used for improving production performance of layer chicken, it is characterised in that: it is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 15~20 parts, Herba Epimedii 7~10 parts, Folium Artemisiae Argyi 50~60 parts, 8~12 parts of Fructus Jujubae, yeast cell wall polysaccharide 7~10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 15~20g adds Bacillus subtilis strain 10~15mL, Bacillus licheniformis strain 3~5mL, Lactobacillus plantarum strain 5~10mL, enterococcus faecalis strain 20~25mL.
2. the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 1, it is characterised in that: it is made up of the raw material mixed fermentation of fermented bacterium and following parts by weight: the Radix Astragali 18 parts, Herba Epimedii 7 parts, Folium Artemisiae Argyi 60 parts, 12 parts of Fructus Jujubae, yeast cell wall polysaccharide 10 parts;The consumption of described fermented bacterium is: the Radix Astragali correspondence of every 18g adds Bacillus subtilis strain 15mL, Bacillus licheniformis strain 3mL, Lactobacillus plantarum strain 5mL, enterococcus faecalis strain 25mL.
3. the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 1 and 2, it is characterised in that: the viable count of described Bacillus subtilis strain is (1.0~3.0) × 109CFU/mL, the viable count of Bacillus licheniformis strain is (1.0~3.0) × 109CFU/mL, the viable count of Lactobacillus plantarum strain is (1.0~5.0) × 108CFU/mL, the viable count of enterococcus faecalis strain is (1.0~5.0) × 108CFU/mL。
4. the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 3, it is characterised in that: the viable count of described Bacillus subtilis strain is 1.5 × 109CFU/mL, the viable count of Bacillus licheniformis strain is 2.0 × 109CFU/mL, the viable count of Lactobacillus plantarum strain is 1.0 × 108CFU/mL, the viable count of enterococcus faecalis strain is 4.0 × 108CFU/mL。
5. an as claimed in claim 1 preparation method for improving the Chinese medicine microecological preparation of production performance of layer chicken, it is characterised in that: after the raw material including taking formula ratio and fermented bacterium mixing, under 25~40 DEG C of conditions, sealed fermenting 7~30 days, to obtain final product.
6. the preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 5, it is characterised in that: the raw material including taking formula ratio and after fermented bacterium mixing, under 32 DEG C of conditions, sealed fermenting 20 days, to obtain final product.
7. the preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 5 or 6, it is characterised in that: the Radix Astragali in described raw material, Herba Epimedii, Folium Artemisiae Argyi, Fructus Jujubae are pulverized in advance and cross 100~200 mesh sieves, obtain medicated powder standby.
8. the preparation method of the Chinese medicine microecological preparation for improving production performance of layer chicken according to claim 7, it is characterised in that: the Radix Astragali in described raw material, Herba Epimedii, Folium Artemisiae Argyi, Fructus Jujubae are pulverized in advance and cross 200 mesh sieves, obtain medicated powder standby.
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106191044A (en) * | 2016-08-05 | 2016-12-07 | 福建农林大学 | A kind of gene engineering method improving lactein plnK yield |
CN106343262A (en) * | 2016-08-30 | 2017-01-25 | 武汉华扬动物药业有限责任公司 | Method for immune enhancing agent for raising procambarus clarkii and the preparing method thereof and application |
CN106994157A (en) * | 2017-03-24 | 2017-08-01 | 哈尔滨中科生物工程有限公司 | A kind of herb fermenting preparation, its preparation method and application for improving performance in layers |
CN107467404A (en) * | 2017-10-23 | 2017-12-15 | 潍坊华光数码设备有限公司 | A kind of feed addictive for laying hen health care and preparation method thereof |
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CN110463856A (en) * | 2019-09-05 | 2019-11-19 | 广东驱动力生物科技股份有限公司 | A kind of feed addictive improving Layer Production Performance |
CN113080335A (en) * | 2021-05-18 | 2021-07-09 | 郑州赛科药业科技有限公司 | Fermented traditional Chinese medicine additive for improving egg poultry production performance and preparation method thereof |
CN114617202A (en) * | 2022-03-29 | 2022-06-14 | 江苏三仪生物工程有限公司 | Compound microecological preparation for improving disease resistance and production performance of ducks as well as preparation method and application of compound microecological preparation |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104161206A (en) * | 2013-07-17 | 2014-11-26 | 河南联合英伟饲料有限公司 | Feed additive for increasing egg yield of hens and preparation method thereof |
CN104171421A (en) * | 2014-08-08 | 2014-12-03 | 河南牧翔动物药业有限公司 | Feed additive for conditioning intestines of animals |
CN104739919A (en) * | 2015-03-30 | 2015-07-01 | 山东宝来利来生物工程股份有限公司 | Fermented astragalus composite preparation as well as preparation method and application thereof |
CN105053593A (en) * | 2015-07-15 | 2015-11-18 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine residues prepared poultry feed additive and preparation method thereof |
CN105076864A (en) * | 2015-09-14 | 2015-11-25 | 石家庄维尔利动物药业有限公司 | Compound preparation used for improving quality of egg shells and preparation method of compound preparation |
CN105146205A (en) * | 2013-08-20 | 2015-12-16 | 沈阳科丰牧业科技有限公司 | Method for improving broiler chicken production performance by means of microecological preparations for broiler chickens |
-
2016
- 2016-04-29 CN CN201610278338.2A patent/CN105767587B/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104161206A (en) * | 2013-07-17 | 2014-11-26 | 河南联合英伟饲料有限公司 | Feed additive for increasing egg yield of hens and preparation method thereof |
CN105146205A (en) * | 2013-08-20 | 2015-12-16 | 沈阳科丰牧业科技有限公司 | Method for improving broiler chicken production performance by means of microecological preparations for broiler chickens |
CN104171421A (en) * | 2014-08-08 | 2014-12-03 | 河南牧翔动物药业有限公司 | Feed additive for conditioning intestines of animals |
CN104739919A (en) * | 2015-03-30 | 2015-07-01 | 山东宝来利来生物工程股份有限公司 | Fermented astragalus composite preparation as well as preparation method and application thereof |
CN105053593A (en) * | 2015-07-15 | 2015-11-18 | 北京生泰尔科技股份有限公司 | Traditional Chinese medicine residues prepared poultry feed additive and preparation method thereof |
CN105076864A (en) * | 2015-09-14 | 2015-11-25 | 石家庄维尔利动物药业有限公司 | Compound preparation used for improving quality of egg shells and preparation method of compound preparation |
Non-Patent Citations (4)
Title |
---|
乔宏兴等: "黄芪-枯草芽孢杆菌复合发酵制剂对肉鸡生产性能及免疫功能的影响", 《中国兽医学报》 * |
武书庚等: "酵母培养物对产蛋鸡生产性能和蛋品质的影响", 《动物营养学报》 * |
赵晓静等: "酵母多糖的生理功能及其在鸡生产中的应用", 《饲料博览》 * |
高明燕等: "微生态制剂对蛋鸡生产性能及蛋品质的影响", 《黑龙江畜牧兽医》 * |
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CN106994157A (en) * | 2017-03-24 | 2017-08-01 | 哈尔滨中科生物工程有限公司 | A kind of herb fermenting preparation, its preparation method and application for improving performance in layers |
CN107467404A (en) * | 2017-10-23 | 2017-12-15 | 潍坊华光数码设备有限公司 | A kind of feed addictive for laying hen health care and preparation method thereof |
CN108576479A (en) * | 2018-05-17 | 2018-09-28 | 杨凌职业技术学院 | A kind of feed addictive of layer chicken and preparation method thereof |
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