CN114651832A - Air refreshing disinfectant extracted from plants and preparation method thereof - Google Patents

Air refreshing disinfectant extracted from plants and preparation method thereof Download PDF

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CN114651832A
CN114651832A CN202210220804.7A CN202210220804A CN114651832A CN 114651832 A CN114651832 A CN 114651832A CN 202210220804 A CN202210220804 A CN 202210220804A CN 114651832 A CN114651832 A CN 114651832A
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disinfectant
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air
air freshening
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江植成
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/12Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08Magnoliopsida [dicotyledons]
    • A01N65/22Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L9/00Disinfection, sterilisation or deodorisation of air
    • A61L9/01Deodorant compositions
    • A61L9/013Deodorant compositions containing animal or plant extracts, or vegetable material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2209/00Aspects relating to disinfection, sterilisation or deodorisation of air
    • A61L2209/20Method-related aspects
    • A61L2209/21Use of chemical compounds for treating air or the like

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention provides a plant-extracted air-refreshing disinfectant and a preparation method thereof. The invention belongs to the technical field of air disinfection. Comprises 10 to 20 parts of rhizoma atractylodis, 5 to 10 parts of folium artemisiae argyi, 3 to 8 parts of folium isatidis, 3 to 8 parts of agastache rugosus, 5 to 10 parts of mint and 5 to 10 parts of honeysuckle according to the parts by mass. Cleaning the above raw materials, oven drying, pulverizing, soaking, filtering, distilling with steam, sterilizing, and inspecting to obtain air refreshing disinfectant. Compared with the prior art, the air refreshing disinfectant is prepared by adopting Chinese medicinal materials extracted from plants, has no toxic or side effect, and can quickly reduce pathogenic microorganisms in space and reduce indoor air pollution; the preparation process disclosed by the invention is simple in flow, easy to operate, environment-friendly, pollution-free, low in production cost and capable of improving the production efficiency.

Description

Air refreshing disinfectant extracted from plants and preparation method thereof
Technical Field
The invention belongs to the technical field of air disinfection, and relates to an air refreshing disinfectant extracted from plants and a preparation method thereof.
Background
With the high development of social material civilization, air pollution, especially indoor air pollution, is greatly increased in degree, so that the disease frequency of a part of human respiratory diseases is increased, and symptoms such as dizziness, fatigue and nausea are caused, so that troubles and troubles are brought to the work and life of many people, the health of people is greatly threatened, and the problem that people have to face how to eliminate and prevent indoor virus and bacterial infection and relieve air pollution is solved.
Based on this, a wide variety of air freshening and disinfecting products are available on the market. The air disinfectants and fresheners in the market at present have larger problems and defects, firstly, most products are only added with some chemical essences, and the products only have aromatic odor and do not have the effects of sterilization and disinfection when sprayed in the air; secondly, the existing products usually adopt chemical products as raw materials, and although the existing products have a certain refreshing and disinfecting function, new pollution is increased; third, traditional medical air disinfection products, although having strong disinfection and sterilization effects, often smell bad (like soda water) and are not acceptable by general people, or disinfection with hydrofluoric acid is easy to cause damage to human body and cannot completely improve indoor air environment.
Disclosure of Invention
In order to solve the problems, the invention aims to provide the air refreshing disinfectant extracted from plants, which has no toxic or side effect, can quickly reduce pathogenic microorganisms in a space and reduce indoor air pollution;
the invention aims to provide a preparation method of the plant-extracted air freshening disinfectant, which has the advantages of simple and easily-operated process flow, low production cost and improved production efficiency.
In order to achieve the purpose, the technical scheme of the invention is as follows:
the invention provides a plant-extracted air freshening disinfectant, which comprises, by mass, 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint and 5-10 parts of honeysuckle.
Further, according to the parts by weight, the optimal effect is achieved when the atractylodes rhizome is 20 parts, the folium artemisiae argyi is 10 parts, the folium isatidis is 4 parts, the agastache rugosus is 6 parts, the mint is 5 parts and the honeysuckle is 8 parts.
Furthermore, the air freshening disinfectant also comprises 3-6 parts of common andrographis herb, 2-6 parts of lemon, 3-8 parts of lavender and 3-8 parts of ephedra herb by mass.
Further, in the present invention, the atractylodes rhizome is pungent and bitter in flavor and warm in nature; it enters spleen, stomach and liver meridians. As early as the Han dynasty, Zhang Zhongjing says that the rhizoma atractylodis can avoid all bad breath. Ming Dynasty Li Shizhen also recorded in Ben Cao gang mu that cang Zhu can remove bad breath, ancient and modern diseases and old Dan, and often burns cang Zhu to remove evil qi when entering home, so the disease of epidemic is used more. Recently Zhang shan Lei (materia Medica) records that rhizoma Atractylodis is fragrant and can avoid dirty, and can take the four seasons of abnormal qi, so it is used for epidemic diseases. Most effectively removing foul and foul smell. In the area of haze, it is advisable to burn the material in a long-term open room and then live in the house. Rhizoma Atractylodis has effects of eliminating dampness, invigorating spleen, dispelling pathogenic wind and dampness, improving eyesight, and eliminating dampness and stagnation of exterior; has obvious effects on eczema itching, impetigo, keratosis, tuberculosis and preventing and controlling malaria symptoms. Rhizoma atractylodis has strong smell, so people often use the rhizoma atractylodis for removing dirt, preventing diseases and indoor air disinfection. The rhizoma atractylodis volatile oil is composed of a series of sesquiterpenes. 55 components have now been isolated and characterized. The main components are as follows: d is elemene, B-ocimene, atractylone, atractyl alcohol, cineol and the like, has obvious sterilization effect on tubercle bacillus, pneumococcus, staphylococcus aureus, large intestine, hay bacillus, pseudomonas aeruginosa, fungi and the like, and is similar to formalin; but is superior to the disinfection of ultraviolet rays and lactic acid.
The rhizoma atractylodis has the efficacy of damp toxin depression and has obvious effects on eczema itching, impetigo, keratosis, tuberculosis and malaria prevention and control. The research on the components of the rhizoma atractylodis mainly focuses on the volatile oil, and the volatile oil mainly contains the components of xanthatin, atractylis lancea alcohol, eucalyptol and the like. Rhizoma atractylodis has strong smell, so people often use the rhizoma atractylodis for removing dirt, preventing diseases and indoor air disinfection. For example, the perfume bag for children at noon festival takes rhizoma atractylodis as main perfume, the rhizoma atractylodis and folium artemisiae argyi are fumigated to kill mosquitoes and flies and sterilize indoors, and the perfume bag has obvious sterilization effect on tubercle bacillus, pneumococcus, staphylococcus aureus, large intestine, hay bacillus, pseudomonas aeruginosa, fungi and the like and is similar to formalin; but is superior to the disinfection of ultraviolet rays and lactic acid. Has certain inhibiting effect on staphylococcus aureus, colon bacillus and pseudomonas aeruginosa.
Folium Artemisiae Argyi is pungent, bitter and warm, and enters liver, spleen and kidney meridians. Warming channels to stop bleeding, dispelling cold and relieving pain; externally used for eliminating dampness and relieving itching. Mainly contains flavonoid, tannin, triterpenes, polysaccharide, trace elements and the like, and has wide pharmacological effects of relieving asthma and cough, resisting allergy, easing pain and diminishing inflammation, enhancing immunity, resisting bacteria and viruses, stopping bleeding and the like. The oleum folium Artemisiae Argyi has inhibiting and killing effects on Staphylococcus aureus, Streptococcus A, Neisseria and pneumococcus, and has certain inhibiting effect on most gram-negative bacteria.
Andrographis paniculata Nees has the effects of clearing away heat and toxic materials, cooling blood and relieving swelling. Can be used for treating acute bacillary dysentery, gastroenteritis, common cold, epidemic cerebrospinal meningitis, tracheitis, pneumonia, pertussis, pulmonary tuberculosis, lung abscess, cholecystitis, hypertension, epistaxis, swelling and pain of oral pharynx, skin ulcer, furuncle, carbuncle, scald due to water and fire, and venomous snake bite. The leaf contains diterpene lactone compounds; in vitro tests, the decoction of herba Andrographitis and the coarse crystal separated from it all have inhibitory or killing effect on some types of leptospira, and the decoction has certain inhibitory effect on pneumococcus, Streptococcus unguis and Catalpa; diterpenoid compounds with andrographolide structure skeleton have obvious effect on severe acute respiratory syndrome caused by virus, and can be used for treating and preventing diseases caused by SARS virus.
The dyers woad leaf is bitter and cold in nature, mainly has the effects of clearing heat, removing toxicity, cooling blood and dissolving spots, is mainly used for treating respiratory system infection, mainly contains indirubine B, indigo, indirubin, tryptophan, tryptanthrin and the like, and has the pharmacological effects of resisting pathogenic microorganisms, resisting endotoxin, resisting inflammation, enhancing immunologic function, relieving fever and the like. The traditional Chinese medicine composition is clinically used for treating epidemic encephalitis B, preventing and treating upper respiratory infection and the like. Folium Isatidis has effects on various bacterial and viral diseases.
Huoxiang fragrant, resolving turbidity, regulating the middle warmer, arresting vomiting, relieving exterior syndrome and relieving summer-heat. Can be used for treating damp turbidity obstruction in middle warmer, abdominal distention emesis, summer-heat dampness exterior syndrome, early stage of damp-warm syndrome, fever and listlessness, chest distress and discomfort, cold-dampness retention of summer-heat, abdominal pain, vomiting and diarrhea, nasosinusitis and headache. Agastache rugosus has obvious antifungal effect; has inhibitory effect on various pathogenic fungi such as Trichophyton schoenleinii; can inhibit multiple pathogenic fungi; anti-leptospira effect, and antiviral effect. The flavonoids in herba Agastaches have antiviral effect. Can inhibit the growth and reproduction of upper respiratory tract pathogen, rhinovirus; agastache rugosus has the function of sterilization, and can be used for removing halitosis, preventing infectious diseases and being used as preservative.
The herba Menthae has pure fragrance, can exanthema and depression, and has effects of refreshing, dispelling pathogenic wind, eliminating inflammation, relieving pain and exciting. It is a pungent and cool sweating and antipyretic medicine, and has antibacterial, antiinflammatory, skin softening, refreshing and refreshing effects. Menthol has different degrees of bacteriostasis to various fungi and bacteria, and staphylococcus epidermidis and bacillus subtilis are sensitive to the menthol.
The honeysuckle has the efficacy of clearing away heat and toxic materials. Can be used for treating wind-heat common cold or fever due to epidemic febrile disease, sunstroke, toxic heat, dysentery, carbuncle, furuncle, pharyngitis, and various infectious diseases. Contains abundant chlorogenic acid, has wide antibacterial effect, luteolin also has antibacterial effect, and other components such as inositol, saponin, tannic acid, etc. have inhibitory effect on various pathogenic bacteria because they contain a large amount of reducing groups. The pathogenic bacteria include Staphylococcus aureus, hemolytic streptococcus, pneumococcus, meningococcus causing heat toxin syndrome in traditional Chinese medicine, typhoid bacillus, paratyphoid bacillus, Shigella, dysentery bacillus, cholera bacillus, Pseudomonas aeruginosa, Escherichia coli, tubercle bacillus and the like causing acute heat infection of intestinal tract.
Lemon, sour and sweet in taste, cool in nature, enters stomach and lung meridians. Promote the production of body fluid, relieve summer-heat, harmonize stomach and prevent abortion. The pharmacological effects are as follows: antibacterial, antiviral and anti-inflammatory; hemostasis is carried out; has antioxidant effect. The citrus lemon extract has obvious inhibiting effect on staphylococcus aureus and killing effect on bacteria capable of forming a biological membrane. The research reports indicate that the extract can not accumulate in any organ whether orally taken or injected by human and animals, the lemon extract is considered to have no toxic and side effects at present and can be taken in a large amount, and the lemon extract has no mutagenicity proved by different detection end points by applying a mouse somatic cell, germ cell and microorganism detection system.
Lavender, pungent in flavor and cool in nature; clearing away heat and toxic material, dispelling wind and relieving itching; has tranquilizing, hypnotic, spasmolytic, antibacterial, antioxidant, and neuroprotective effects. The lavender essential oil has analgesic, anti-convulsion, anti-depression, antiinflammatory, antirheumatic, antibacterial, antispasmodic, antiviral, antibacterial, flatulence removing, choleretic, scar promoting, exciting, and cell activity promoting effects. Simultaneously has the functions of resisting lipid peroxidation and benefiting gallbladder, also has the characteristics of dispelling wind, resisting flatulence and acute abdominal pain, and has good effect of killing mosquitoes.
Ma Huang is pungent and bitter in flavor and warm in nature. Unprocessed with strong sweating ability, stir-baked with honey slightly slowly, enters lung and bladder meridians. The pharmacological effects are wide, and the reported effects include sweating, diuresis, cough relieving, asthma relieving, antiallergic, blood pressure increasing, central nervous system exciting, antipyretic, antiviral and neuromuscular transmission influencing. In recent years, ephedra has been found to have the effects of improving chronic renal failure, promoting fat synthesis of fat cells, influencing cellular immunity, scavenging oxygen free radicals, and resisting formation of acute blood stasis.
The invention provides a preparation method of a plant-extracted air freshening disinfectant, which comprises the following steps:
s1: cleaning and drying: selecting the raw materials, respectively cleaning and drying;
s2: crushing: respectively crushing the dried traditional Chinese medicine raw materials in the step S1;
s3: soaking: respectively weighing the crushed traditional Chinese medicine raw materials in the S2 according to a certain weight ratio, mixing, and then soaking with clean water at normal temperature for one time to form liquid medicine with precipitates;
s4: and (3) filtering: filtering the liquid medicine soaked in the S3 coarse filter, fine filter and filtering precipitate;
s5: steam distillation: extracting the filtered liquid medicine in the step S4 by a steam distillation method;
s6: and (3) sterilization: sterilizing the distillate obtained by distilling in the S5 by using an instant sterilizer;
s7: and (4) checking: packaging and inspecting to obtain the finished product.
Further, the amount of the clean water in the step S3 is 6 times of the weight of the mixed medicine.
Further, the using method of the air sterilization freshener comprises the following steps: adopting an electronic spraying or ultrasonic spraying method, and mixing the liquid medicine according to the proportion of 1: 1 is diluted by clear water or added into an electronic spraying device or an ultrasonic atomizer directly by stock solution to be atomized and dispersed in indoor space, can effectively reduce the number of viruses and bacteria in the space in a short time and act on a human body to form a protective medicine film on the skin and the surface layer of respiratory mucosa, thereby being capable of treating various respiratory diseases, preventing the cross propagation of bacterial and viral respiratory diseases, refreshing air, expelling parasites and relieving itching.
Compared with the prior art, the invention has the beneficial effects that:
firstly, the air freshening disinfectant comprises Chinese medicinal components such as rhizoma atractylodis, folium artemisiae argyi, folium isatidis, agastache rugosus, mint, honeysuckle, common andrographis herb, lemon, lavender, ephedra herb and the like. The rhizoma atractylodis comprises the following main components: d is elemene, B-ocimene, atractylone, atractyl alcohol, cineol and the like, has obvious sterilization effect on tubercle bacillus, pneumococcus, staphylococcus aureus, large intestine, hay bacillus, pseudomonas aeruginosa, fungi and the like, and is similar to formalin; the folium artemisiae argyi contains complex chemical components, mainly contains volatile oil, and then flavonoid, tannin, triterpenes, polysaccharides, trace elements and the like, and has wide pharmacological effects of relieving asthma and cough, easing pain and diminishing inflammation, enhancing immunity, resisting allergy, bacteria, viruses, stopping bleeding and the like; the volatile oil has the effects of inhibiting and killing staphylococcus aureus, streptococcus A, Neisseria and pneumococcus and has certain effect of inhibiting most gram-negative bacteria; the herba Agastaches volatile oil contains patchouli alcohol and flavonoids, and can inhibit growth and reproduction of most of skin pathogenic bacteria, especially responsible bacteria related to human body bromhidrosis and loempe; can stimulate gastric mucosa, promote gastric secretion, and enhance digestive ability; has obvious effects of relieving cough, eliminating phlegm, resisting inflammation and relieving pain. Folium Isatidis mainly contains indirubine B, indigo, indirubin, tryptophan, tryptanthrin, etc.; the pharmacological actions of the traditional Chinese medicine composition mainly comprise resisting pathogenic microorganisms, resisting endotoxin, resisting inflammation, enhancing immunologic function, relieving fever and the like; it can be used for treating various bacterial and viral diseases. The honeysuckle volatile oil has strong in-vitro antibacterial effect; has obvious bacteriostatic effect on staphylococcus aureus, bacillus subtilis and staphylococcus haemolyticus. Linalool, geraniol and alpha-terpineol also have antibacterial and antiviral effects. Linalool can relieve asthma and cough, and treat infantile pneumonia and tonsillitis. The main chemical components of the mint volatile oil are alcohol, ketone, ester, terpene and terpene alkane compounds, and the mint volatile oil has obvious inhibiting effect on bacteria and fungi such as pseudomonas aeruginosa, staphylococcus aureus, beer yeast, escherichia coli, rhizopus, aspergillus niger and the like.
In summary, through the organic combination of the medicines, the main effective components of the medicines in the formula are various, but all the medicines have obvious antibacterial, bactericidal and antiviral effects and treatment effects on various respiratory diseases; after the components are combined together, the effects are wider; after being prepared according to specific proportion and amount, the medicine achieves the aims of fragrance, no toxicity and improved curative effect. In the prescription, the rhizoma atractylodis and the folium artemisiae argyi are pungent, bitter and warm in taste, and are mainly used for eliminating dampness and dispelling cold; agastache rugosus is pungent in flavor and slightly warm in nature, and is used for assisting in resolving turbidity with aromatics; honeysuckle flower, flos Lonicerae, sweet in taste and cold in nature, and dyers woad leaf, bitter in taste and cold in nature, are used for clearing heat and removing toxicity; mint is pungent in flavor and cool in nature, and is used to dispel wind and release exterior. The whole formula has the effects of eliminating dampness and cold, clearing away heat and toxic materials, dispelling wind and relieving exterior syndrome. The whole preparation is both pungent, bitter, sweet and salty in coordination with the addition and blending of sodium chloride at the later stage of the preparation; the temperature and the cooling are moderate; the medicine enters the middle meridians and is good for heart, liver, spleen, lung and kidney; the medicine property is not biased, so that the patients are not too cold or too warm; and the disinfectant is disinfected and sterilized only in a spraying and atomizing mode in a specific space or environment, has aromatic smell and no toxicity, and slightly acts on skin and mucosa in an aerosol state, so that the safety is extremely high.
Secondly, the preparation method of the air refreshing disinfectant is simpler, the process flow is simple and easy to operate, the preparation cost is reduced, and the production efficiency is improved; in addition, the medicinal components of the liquid medicine are protected from being damaged in the preparation process, and the medicinal effect of the prepared traditional Chinese medicine liquid is ensured; in the storage process, the deposit is not easy to generate, the inspection regulation of the product on visible foreign matters is met, and the safety of medicine is ensured.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In order to realize the purpose, the technical scheme of the invention is as follows:
example 1: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint and 5-10 parts of honeysuckle.
Example 2: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle and 2-6 parts of lemon.
Example 3: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle and 3-8 parts of lavender.
Example 4: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle and 3-6 parts of common andrographis herb.
Example 5: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle, 3-6 parts of andrographis paniculata and 2-6 parts of lemon.
Example 6: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle, 3-6 parts of andrographis paniculata and 3-8 parts of lavender.
Example 7: 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint, 5-10 parts of honeysuckle, 3-6 parts of common andrographis herb and 3-8 parts of ephedra herb.
The finished product is prepared by adopting the processes of cleaning, drying, crushing, soaking, filtering, sterilizing and inspecting in the above examples 1-7.
Control test: the air-freshening and purifying solutions prepared in examples 1 to 7 (test group) were compared with the conventional peracetic acid fumigation method (control group 1), and the burning disinfection method of atractylodes rhizome and artemisia leaf (control group 2) and the ultraviolet lamp irradiation disinfection method (control group 3).
Control group 1: 15.9% peroxyacetic acid from Jilin Cornell, Inc.
Control group 2: raw rhizoma atractylodis and folium artemisiae argyi.
Control group 3: 30W ultraviolet lamp.
The test site comprises: an operating room: 4 operating rooms with the same volume (5m x 5m x 3m) and completely consistent indoor structures (doors, windows and indoor facilities) are selected as disinfection objects and randomly drawn during the test. 4 sickbeds in a common ward (2.5m x 5m x 3 m); dressing room (3m x 4.5.5 4.5m x 3 m).
The test method comprises the following steps:
test groups: the test was divided into 4 groups, using the test groups prepared in examples 1 to 7, by means of an electric ultra-micro-particle nebulizer, respectively in amounts per cubic meter: 0.25g, 0.5g, 1.0g, 2.0g air sanitization was performed on 4 operating rooms drawn at random. Each group was tested in parallel 15 times.
Control group 1: the method for disinfecting air fumigated by peracetic acid comprises the following steps: taking 15.9 percent of peroxyacetic acid stock solution 8mbm-3Heating and fumigating by alcohol lamp.
Control group 2: the air sterilization method for burning rhizoma atractylodis and folium artemisiae argyi comprises the following steps: soaking rhizoma Atractylodis and folium Artemisiae Argyi in 95% ethanol 1 part for 24 hr, placing in a bowl, and directly igniting to smoke.
Control group 3: one 30W ultraviolet lamp tube directly irradiates for 1h, and the lamp tube is 2.5m away from the ground.
The 4 methods are compared and tested for 15 times.
The experimental results are as follows:
the disinfection effect of the 4 air disinfection methods is shown in table 1. The results show that the disinfection effect of the test group is better than that of the control group.
Table 1: comparison of the Disinfection Effect of 4 air Disinfection methods (i + -s, n ═ 15)
Figure BDA0003537279580000081
Note: p <0.01 compared to peracetic acid fumigation; p <0.01 compared to the uv lamp set; compared with the atractylodes rhizome and artemisia leaf burning group, P is less than 0.05.
The disinfection effect of the test group applied to the general ward and the dressing room in other areas of the hospital is shown in the table 2 (the disinfection effect is shown in the table 2)
TABLE 2 disinfectant effect of air freshening and purifying liquid (l + -s, n ═ 15)
Figure BDA0003537279580000091
Note: p <0.01 compared to before sterilization
The 4 disinfection methods are respectively performed for 30 min, 60 min, 120 min and 240min before and after disinfection, and air samples are collected according to a standard sedimentation method by referring to a microbial contamination monitoring technology in disinfection technical specification (2002), namely, a blood agar plate with the diameter of 9cm is placed at a fixed position (3 points are selected from the middle point and two ends of the diagonal line of an operating room to be 1m away from the wall), placed at a height level of 1m away from the ground and exposed for 5min, covered, sent to a culture room for culture, cultured in a 37T incubator for 48h, then subjected to colony counting (unit cfu) under an optical microscope, and the average value of the colony counts of 3 culture dishes is taken as an index. And carrying out conventional bacteria culture and detection according to 'epidemic prevention microorganism detection operation rules'.
As a result: the effect of the test group is better than that of the control group, and the expected effect is achieved when the test group is applied to different areas. And (4) conclusion: the experimental group has definite air disinfection effect, low price and no toxic or side effect on human body.
And (4) effect judgment:
according to various environmental air sanitation standards in the Disinfection technical Specification of the ministry of health. The general operating room belongs to the U-class environment, the number of bacteria in the air is required to be W200 cfu-m- \ ward, the dressing room belongs to the HI-class environment, and the number of bacteria in the air is required to be W500 cfu-m-30.
Discussion of the results:
the rhizoma atractylodis and the folium artemisiae argyi are both commonly used traditional Chinese medicines, the rhizoma atractylodis is dry rhizome of rhizoma atractylodis of compositae, the folium artemisiae argyi is dry leaf of folium artemisiae argyi of compositae, the medicinal history is long, the rhizoma atractylodis and the folium artemisiae argyi are respectively recorded in Shennong herbal classic and famous medical records, and the rhizoma atractylodis, the folium artemisiae argyi and the folium artemisiae argyi have the effects of relieving cough, eliminating phlegm, relieving asthma, resisting allergy and the like when being taken orally. In the morning, people can use the smoke of burning two medicines to disinfect air, and recently, people have conducted intensive research on the method for disinfecting air by burning rhizoma atractylodis and folium artemisiae argyi. The main bactericidal components include atractylol, atractyl, leaf alcohol, etc. The effective components of rhizoma Atractylodis and folium Artemisiae Argyi are extracted for air sterilization, and can kill and inhibit Staphylococcus aureus, type B hemolytic streptococcus, Escherichia coli, Bacillus proteus, Bacillus diphtheriae, and Bacillus tuberculosis. The hydrogen peroxide is mainly used for sterilizing through oxidation, and nascent oxygen generated by decomposition of the hydrogen peroxide is oxidized to convert sulfhydryl of bacterial protein into disulfide, so that the bacterial metabolic disorder is dead, and no residual toxicity exists after decomposition. Comparing the air disinfection with the traditional burning method of the rhizoma atractylodis and the folium artemisiae argyi and the peroxyacetic acid fumigation and ultraviolet lamp irradiation disinfection methods which are clinically used at present, the results show that the operating room disinfected by the 4 disinfection methods all reaches the II and III environmental air sanitation standards in the disinfection technical Specification, and the disinfection effect of the air freshening purifying liquid spray is superior to that of the control group.
The air purifying and refreshing liquid is used for air disinfection, is not limited by time, temperature and humidity, emits light aromatic traditional Chinese medicine smell in the air during disinfection, can play a role of humidifying the air while disinfecting, has no stimulation or other toxic and side effects on human skin, mucous membrane and respiratory tract, can be accepted by patients and workers, and has the advantages of abundant material-taking resources, stable property and simple use. The patient does not need to be moved during the disinfection period, and the medical staff can also treat and nurse the patient as usual, so the method is also suitable for air disinfection in various places (such as crowded places of people such as markets, movie theaters, waiting rooms and the like), and is particularly suitable for air disinfection of wards with more critical patients and inconvenience for the patient and the medical staff to leave, and the time and the labor are saved.
The above embodiments are only for illustrating the present invention, and the scope of the present invention is not limited to the above embodiments. The objectives of the present invention can be achieved by the ordinary skilled person in the art according to the disclosure of the present invention and the ranges of the parameters.

Claims (9)

1. The plant-extracted air freshening disinfectant is characterized by comprising, by mass, 10-20 parts of rhizoma atractylodis, 5-10 parts of folium artemisiae argyi, 3-8 parts of folium isatidis, 3-8 parts of agastache rugosus, 5-10 parts of mint and 5-10 parts of honeysuckle.
2. The plant-extracted air freshening disinfectant of claim 1 wherein the atractylodes rhizome is 20 parts, the artemisia leaf is 10 parts, the isatis leaf is 4 parts, the agastache rugosus is 6 parts, the mint is 5 parts, and the honeysuckle is 8 parts.
3. A plant extract air freshening disinfectant as claimed in claim 1 which further includes 2-6 parts lemon.
4. The plant-derived air freshening disinfectant of claim 1 further comprising 3-6 parts of andrographis paniculata.
5. The plant-derived air freshening disinfectant of claim 1 further comprising lavender 3-8 parts.
6. The plant-derived air freshening disinfectant of claim 1 further comprising 3-6 parts of andrographis paniculata, 3-8 parts of lavender.
7. The plant-derived air freshening disinfectant of claim 1 further comprising 3-6 parts of andrographis paniculata, and 3-8 parts of ephedra.
8. A method of preparing a plant-derived air freshening disinfectant as claimed in any one of claims 1 to 7, including the steps of:
s1: cleaning and drying: selecting the raw materials, respectively cleaning and drying;
s2: crushing: respectively crushing the dried traditional Chinese medicine raw materials in the step S1;
s3: soaking: respectively weighing the crushed traditional Chinese medicine raw materials in the S2 according to a certain weight ratio, mixing, and then soaking with clean water at normal temperature for one time to form liquid medicine with precipitates;
s4: and (3) filtering: filtering the liquid medicine soaked in the S3 coarse filter, fine filter and filtering precipitate;
s5: steam distillation: extracting the filtered liquid medicine in the step S4 by a steam distillation method;
s6: and (3) sterilization: sterilizing the distillate obtained by distilling in the S5 by using an instant sterilizer;
s7: and (4) checking: packaging and inspecting to obtain the finished product.
9. The method of claim 8, wherein the amount of cleaning water used in S3 is 6 times the weight of the mixed medicines.
CN202210220804.7A 2022-03-08 2022-03-08 Air refreshing disinfectant extracted from plants and preparation method thereof Pending CN114651832A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1156540A (en) * 1996-09-24 1997-08-13 南召县供销合作社联合社 Air pure and fresh disinfectant using folium artemisiae argyi oil as main and preparing process thereof
CN101530112A (en) * 2009-03-23 2009-09-16 深圳市武大金球中药现代化工程技术研究中心 An air sterilization freshener, a preparation method and a using method thereof
CN103444801A (en) * 2013-08-19 2013-12-18 河北省科学技术情报研究院 Traditional Chinese medicinal bactericidal freshening preparation for sterilizing library
CN111134148A (en) * 2020-02-06 2020-05-12 宋小冰 Traditional Chinese medicine aromatherapy air disinfectant

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1156540A (en) * 1996-09-24 1997-08-13 南召县供销合作社联合社 Air pure and fresh disinfectant using folium artemisiae argyi oil as main and preparing process thereof
CN101530112A (en) * 2009-03-23 2009-09-16 深圳市武大金球中药现代化工程技术研究中心 An air sterilization freshener, a preparation method and a using method thereof
CN103444801A (en) * 2013-08-19 2013-12-18 河北省科学技术情报研究院 Traditional Chinese medicinal bactericidal freshening preparation for sterilizing library
CN111134148A (en) * 2020-02-06 2020-05-12 宋小冰 Traditional Chinese medicine aromatherapy air disinfectant

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Title
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