CN102792976B - Herbal disinfectant for space spray disinfection - Google Patents
Herbal disinfectant for space spray disinfection Download PDFInfo
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- CN102792976B CN102792976B CN201210302737XA CN201210302737A CN102792976B CN 102792976 B CN102792976 B CN 102792976B CN 201210302737X A CN201210302737X A CN 201210302737XA CN 201210302737 A CN201210302737 A CN 201210302737A CN 102792976 B CN102792976 B CN 102792976B
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Abstract
The invention discloses a herbal disinfectant for space spray disinfection. The herbal disinfectant is composed of fourteen pharmaceuticals including rhizoma atractylodis, rhubarb, coptidis rhizoma, herba artemisiae scopariae, radix angelicae dahuricae, cyrtomium rhizome, sweet wormwood herb, betel nuts, cloves, costustoot, borneol, mint, chrysanthemum, and agastache. The medicinal materials selected for the herbal disinfectant for space spray disinfection of the present invention have the functions of clearing heat and removing toxicity, removing miasmic toxin and dispelling filth, restoring consciousness and opening the orifices, supporting body healthy qi, and fending off evil. The volatile oils, alkaloids and other active ingredients contained in the medicinal materials have different levels of direct inhibition or killing function for a variety of bacteria, viruses, fungi, and spirochetes, mycoplasma, etc. The present invention utilizes a scientific method to extract total extract from the medicinal materials for preparing the space spray medicament, and has a good disinfection effect.
Description
Technical field
The present invention relates to a disinfectant of the autonomic drug for the space spraying disinfection.
Background technology
Air borne, droplet transmission are the main routes of transmission of many infectious diseases, as meningitis, varicella, influenza, Influenza A H1N1, Hand-Food-Mouth Disease etc., all in various degree pass through the air droplet transmission, therefore to the crowded interior space, particularly the more public place of Susceptible population such as the poor old man of physique, child, weak crowd carries out disinfection, kill airborne pathogenic microorganisms, being to prevent cross-infection, keep off infection and propagate and popular important measures, is also one of prevention and control infectious disease method now commonly used.
At present space disinfection method commonly used comprise that the medicine air is stifling, the methods such as medicine spraying and ultraviolet ray irradiation, ozone generator, common drug has the chemicalss such as Peracetic acid, lactic acid, hydrogen peroxide, formaldehyde, 84 thimerosals, glutaraldehyde, these medicines and sterilization method can be killed the space pathogenic microorganisms in various degree, obtain effect preferably, but all there is toxicity, to human body mucous membrane, skin irritation, to metal protection, the defects such as peculiar smell retains, affect health, during sterilization, personnel must leave the theatre, uncomfortable tenant in common's environment disinfected.Chinese traditional medicine is relatively paid attention to the space disinfection prevent disease always, modern study confirms, Chinese medicine not only can be treated disease, many TCM in Vitros have stronger antibiosis and antiviral functions, use rhizoma atractylodis, the Chinese medicines such as tarragon are made the fragrant burning of medicine, carrying out sootiness, to keep away pest be exactly the air disinfection method that the traditional Chinese medical science is traditional, folks of china also has the Dragon Boat Festival to commonly use rhizoma atractylodis, tarragon, realgars etc. fumigate a room to drive miasma, except dirty custom, but Chinese medicine burning chimney kiln also has weak point, the more smog that produces can cause side effect, the smoke particles contaminated air that suspends, respiratory mucosa is produced and stimulates.The present invention utilizes modern technologies, extract the total composition of Chinese medicine, make the autonomic drug disinfectant for the space spraying disinfection, have environmental protection, can when the indoor people of having, sterilize, kill air and the advantages such as the body surface microorganism effect is desirable, harmless, use safety, corrosion-free effect, and fragrant odour, have the fresh air effect.
Summary of the invention
The object of the invention is to provide a disinfectant of the autonomic drug for the space spraying disinfection.
In order to realize the foregoing invention purpose, raw material composition and weight proportion thereof that the present invention makes this effective ingredient are: 50 parts of rhizoma atractylodis, 15 parts of rheum officinales, 15 parts of the coptiss, 15 parts of oriental wormwoods, 10 parts of the roots of Dahurain angelica, 10 parts of rhizome of cyrtomium, 10 parts of sweet wormwoods, 5 parts of betel nuts, 5 parts of cloves, 10 parts of the banksia rose, 2 parts of borneols, 15 parts of peppermints, 10 parts of chrysanthemums, 15 parts of wrinkled giant hyssops.
The present invention is comprised of rhizoma atractylodis, rheum officinale, the coptis, oriental wormwood, the root of Dahurain angelica, rhizome of cyrtomium, sweet wormwood, betel nut, cloves, the banksia rose, borneol, peppermint, chrysanthemum, 14 kinds of medicines of wrinkled giant hyssop for the autonomic drug disinfectant of space spraying disinfection, the present invention is for the selected medicinal material of autonomic drug disinfectant of space spraying disinfection, have clearing heat and detoxicating, be in harmonious proportion all gas, dampness elimination and in, the function such as eliminate dampness with aromatics, have and keep away dirty, consciousness regaining, help body healthy tendency, get rid of evils and keep away the effect of epidemic disease except miasma.modern study confirms, the volatile oil that above-mentioned medicinal material contains, the plurality of active ingredients such as alkaloid, can directly suppress multiple pathogenic microorganisms, to Staphylococcus epidermidis, micrococcus catarrhalis, bacillus anthracis, diphtheria bacillus, staphylococcus aureus, Pseudomonas aeruginosa, shigella dysenteriae, tubercle bacillus, Escherichia coli, first type and Bacillus paratyphosus B, comma bacillus, influenza virus, polyovirus, Coxsackie virus, rhinovirus, achorion, Candida albicans, trichophyta etc. various bacteria, virus, fungi and conveyor screw, mycoplasmas etc. have direct inhibition in various degree or kill function, in addition, some active ingredients contained in these medicinal materials have immunoregulation effect to human body, Effective Component of Chinese Medicine, by the suction of mouth and nose, can promote immunological regulation and the inducement interferon of leucocyte division, increase leucocyte number, participation body, improves the immunologic function of body.The present invention utilizes scientific method to extract medicinal substances extract, makes the space spraying medicament, the value that has better Disinfection Effect and prevent disease to propagate.
Autonomic drug for space spraying disinfection disinfectant provided by the present invention, its preparation method is, first with alcohol extract again the extraction method extracted of water extract medicinal ingredient, after rhizoma atractylodis in being about to fill a prescription, rheum officinale, the coptis, oriental wormwood, the root of Dahurain angelica, rhizome of cyrtomium, sweet wormwood, betel nut, cloves, the banksia rose, peppermint, chrysanthemum, wrinkled giant hyssop medicinal material clean and dry, mixed powder is broken into even meal, by following flow process, extracts drug ingedient:
1, medicinal material coarse powder is placed in the refluxing extraction device, adds proper amount of edible level absolute ethyl alcohol, heating and refluxing extraction 60 minutes, separating anhydrous ethanol extract, cooling standby;
2, by the medicinal material coarse powder after the absolute ethyl alcohol extraction, add proper amount of edible level 75% ethanol, heating and refluxing extraction 60 minutes, then the separating alcohol extract, add borneol to dissolve, and is cooling standby;
3, by the medicinal material coarse powder after 75% alcohol extract, then add appropriate distilled water, be heated to 100° centigrade, refluxing extraction 90 minutes, discard the dregs of a decoction, separates the distilled water extract, and is cooling standby;
4, cooled medicine absolute ethyl alcohol extract, 75% ethanol extract, distilled water extract are mixed, obtain the total extract of medicine;
5, with proper amount of edible level ethanol, distilled water, regulate the capacity that mixes rear total extract, remove by filter contamination precipitation, every 1 kilogram of medicinal material is finally made 2000 milliliters of extracts that contain amount of alcohol 30%, i.e. the present invention is for the autonomic drug disinfectant of space spraying disinfection, and lucifuge stores for future use.
Usage of the present invention is: spray-on process is carried out interior space sterilization, 100 milliliters of every 100 cubic metres of spraying consumptions.
The present invention is for the autonomic drug disinfectant of space spraying disinfection, the effect that the performance traditional Chinese medicine is prevented and cured diseases, use safety, and is harmless, nonirritant, can when the indoor people of having, sterilize, satisfactory for result, carry out space disinfection, especially at space, public arena spraying disinfections such as hospital, school, cinemas, the spread and epidemic that can keep off infection, and smell delicate fragrance has the fresh air effect, has great application value and market prospects.
The invention embodiment
By following medicament composing prescription consumption, prepare medicine: 50 kilograms of rhizoma atractylodis, 15 kilograms of rheum officinales, 15 kilograms of the coptiss, 15 kilograms of oriental wormwoods, 10 kilograms of the roots of Dahurain angelica, 10 kilograms of rhizome of cyrtomium, 10 kilograms of sweet wormwoods, 5 kilograms of betel nuts, 5 kilograms of cloves, 10 kilograms of the banksia rose, 2 kilograms of borneols, 15 kilograms of peppermints, 10 kilograms of chrysanthemums, 15 kilograms of wrinkled giant hyssops.After rhizoma atractylodis in formula, rheum officinale, the coptis, oriental wormwood, the root of Dahurain angelica, rhizome of cyrtomium, sweet wormwood, betel nut, cloves, the banksia rose, peppermint, chrysanthemum, the cleaning of wrinkled giant hyssop medicinal material are dried, mixed powder is broken into even meal, by following flow process, extract drug ingedient: 1, medicinal material coarse powder is placed in the refluxing extraction device, add proper amount of edible level absolute ethyl alcohol, heating and refluxing extraction 60 minutes, separating anhydrous ethanol extract, cooling standby; 2, by the medicinal material coarse powder after the absolute ethyl alcohol extraction, add proper amount of edible level 75% ethanol, heating and refluxing extraction 60 minutes, then the separating alcohol extract, add borneol to dissolve, and is cooling standby; 3, by the medicinal material coarse powder after 75% alcohol extract, then add appropriate distilled water, be heated to 100° centigrade, refluxing extraction 90 minutes, discard the dregs of a decoction, separates the distilled water extract, and is cooling standby; 4, cooled medicine absolute ethyl alcohol extract, 75% ethanol extract, distilled water extract are mixed, obtain the total extract of medicine; 5, with proper amount of edible level ethanol, distilled water, regulate capacity and the concentration of alcohol that mixes rear total extract, remove by filter contamination precipitation, finally make 374000 milliliters of solution that contain amount of alcohol 30%, be the disinfectant of the autonomic drug for the space spraying disinfection of the present invention, airtight, lucifuge, store for future use.
Below while by practical example, illustrating autonomic drug disinfectant of the present invention for the space spraying disinfection to the killing effect of bacterium.
One, using method
Get the present invention and add high-pressure sprayer for the autonomic drug disinfectant of space spraying disinfection, spray-on process is carried out interior space sterilization, 100 milliliters of every 100 cubic metres of spraying consumptions.
Selecting the larger hospital outpatient transfusion room of flow of the people is place to use, the high 3.5m in room, area 45m
2, 23～26 ℃ of indoor temperatures, relative moisture 40%～60%.After door and window is closed, under personnel's proper flow state, use autonomic drug disinfectant of the present invention to add in high-pressure sprayer, spray-on process is carried out interior space sterilization.
Use autonomic drug disinfectant sterilization of the present invention first 30 minutes and the sampling in latter 60 minutes of sterilizing, carry out air microbe and cultivate the controlled observation Disinfection Effect.Sampling method is, uses the Micro-Organism Culture Dish of diameter 90mm, at the center, room and four angular distance wall 1m places respectively get 1 point, height is apart from ground 90cm, and Micro-Organism Culture Dish was exposed in air after 5 minutes, and row is cultivated by microorganism, put 37 ℃ of incubators and cultivated 48 hours, the statistics clump count.By the regulation in Ministry of Public Health's " hospital disinfection technical specification ", calculate bacterial inactivation rate.Controlled observation is three days continuously, adds up autonomic drug disinfectant space disinfection effect of the present invention.
Two, result
Before sterilization, the rear 60min air microbe cultivation results of 30min and sterilization is in Table one.Result shows, autonomic drug disinfectant of the present invention is good to the killing effect of bacterium during for the space spraying disinfection.Any bad reaction does not appear in on-the-spot crowd, and smell is pure and fresh, can clean air.
Table one air is cultivated microbe colony and is counted result
| Project | First day | Second day | The 3rd day | The 4th day |
| (cfu/m before sterilization 3) | 563 | 468 | 481 | 412 |
| (cfu/m after sterilization 3) | 69 | 32 | 43 | 29 |
| Bacterial inactivation rate | 87.7％ | 93.2％ | 91.1％ | 93.0％ |
In a word, autonomic drug for space spraying disinfection disinfectant of the present invention, have the advantages such as application safety, easy and simple to handle, cheap, economical and practical, environmental protection, be applicable to the public arenas such as family and hospital, school, cinema and carry out the space spraying disinfection, the value that has better Disinfection Effect and prevent disease to propagate.
Claims (1)
1. the disinfectant of the autonomic drug for the space spraying disinfection, is characterized in that ingredients and the weight proportion thereof of making this autonomic drug disinfectant are: 50 parts of rhizoma atractylodis, 15 parts of rheum officinales, 15 parts of the coptiss, 15 parts of oriental wormwoods, 10 parts of the roots of Dahurain angelica, 10 parts of rhizome of cyrtomium, 10 parts of sweet wormwoods, 5 parts of betel nuts, 5 parts of cloves, 10 parts of the banksia rose, 2 parts of borneols, 15 parts of peppermints, 10 parts of chrysanthemums, 15 parts of wrinkled giant hyssops.
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| CN1168765A (en) * | 1996-06-17 | 1997-12-31 | 安永 | Strong deodorizing and sterilizing agent |
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
| CN101745142A (en) * | 2008-12-21 | 2010-06-23 | 赵伶 | Chinese medicine sterilizing and bacteriostasis coating material for medical instruments |
| CN101530112A (en) * | 2009-03-23 | 2009-09-16 | 深圳市武大金球中药现代化工程技术研究中心 | An air sterilization freshener, a preparation method and a using method thereof |
| CN101829260B (en) * | 2009-07-10 | 2012-01-18 | 南京中医药大学 | Chinese medicine sachet for preventing and treating influenza and preparation method thereof |
| CN101658190B (en) * | 2009-08-29 | 2011-11-30 | 夏焰明 | Liquid preparation with combination of vinegar and air-disinfecting traditional Chinese medicines |
| CN102349991A (en) * | 2011-05-29 | 2012-02-15 | 王红芳 | Composition for killing virus and preventing influenza and cold prevention plaster prepared by composition |
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| CN106259489A (en) * | 2015-05-18 | 2017-01-04 | 青海亚华生物科技有限公司 | A kind of novel skin antibacterial liquid and clothes soak |
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