CN105010424A - Disinfectant composition - Google Patents

Disinfectant composition Download PDF

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Publication number
CN105010424A
CN105010424A CN201510409526.XA CN201510409526A CN105010424A CN 105010424 A CN105010424 A CN 105010424A CN 201510409526 A CN201510409526 A CN 201510409526A CN 105010424 A CN105010424 A CN 105010424A
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China
Prior art keywords
parts
chrysanthemum
coptis
antiseptic composition
volatile oil
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Pending
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CN201510409526.XA
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Chinese (zh)
Inventor
吴友能
陈�光
吴丹
吴铎
曹子燚
郑新宇
张圣华
朱明峰
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Jiangsu Shentao Enviornmental Protection Science & Technology Co Ltd
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Jiangsu Shentao Enviornmental Protection Science & Technology Co Ltd
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Priority to CN201510409526.XA priority Critical patent/CN105010424A/en
Publication of CN105010424A publication Critical patent/CN105010424A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a disinfectant composition. The disinfectant composition is prepared from the following Chinese herbal medicine raw materials in parts by weight: 15-25 parts of cortex phellodendri , 15-25 parts of chrysanthemum flowers, 15-25 parts of coptidis rhizoma, 10-15 parts of lithospermum, 10-15 parts of fructus cnidii, 10-15 parts of melia azedarach flowers, 10-15 parts of lysimachia chiristinae hance, 5-10 parts ofcinnamon, 5-10 parts of tribulus terrestris, 5-10 parts of mint, 5-10 parts of ecucalytypus leaves and 5-10 parts of solidago virgaurea. The disinfectant composition disclosed by the invention has remarkable bactericidal effect, is short in sterilizing time, good in sterilizing effect, free of toxic or side effect, and suitable for sterilizing public places such as hospitals, kindergartens, schools, cinemas and the like for a long term.

Description

A kind of antiseptic composition
Technical field
The present invention relates to a kind of disinfectant, in particular to a kind of antiseptic composition.
Background technology
Disinfectant, for killing pathogenic microorganism on communication media, makes it reach innoxious requirement, is eliminated by pathogenic microorganism outside human body, cuts off the route of transmission of infectious disease, reaches the object controlling infectious disease.Disinfectant of the prior art, general employing " chemosterilant ", adopts chemical compound killing microorganisms to make it reach sterilizing requirement." chemosterilant " has spread effect to human body, taste is unpleasant, corrosivity is stronger, easily causes danger.People also adopt the mode of ultraviolet sterilization, and this mode needs to operate in unmanned situation.And although ultraviolet germicidal effect is comparatively strong, very weak to the penetration capacity of object.It is applicable to thermo-labile article and mesa surfaces sterilization, and ultraviolet sterilization is to air sterilization effect extreme difference.
Modern study confirms, Chinese medicine not only can disease therapy, many TCM in Vitros have stronger antibiosis and antiviral functions, the burning of medicine perfume is made with the Chinese medicine such as rhizoma atractylodis, tarragon, carrying out sootiness, to keep away pest be exactly the traditional air disinfection method of the traditional Chinese medical science, folks of china also has the Dragon Boat Festival to commonly use rhizoma atractylodis, tarragon, realgar etc. to fumigate a room to drive miasma, except dirty custom, but Chinese medicine burning chimney kiln also has weak point, the more smog produced can cause side effect, the smoke particles contaminated air suspended, produces respiratory mucosa and stimulates.And existing Chinese medicine antiseptic is compared with chemosterilant with ultraviolet sterilization, all there is the problems such as sterilization sterilization time is long, bactericidal effect is not remarkable.
Summary of the invention
The invention provides a kind of antiseptic composition, this antiseptic composition has significant bactericidal action, and sterilizing time is short, and bactericidal effect is good, has no side effect, and suitable prolonged application is in the sterilization of the public places such as hospital, kindergarten, school.
Particularly, one aspect of the present invention provides a kind of antiseptic composition, and this herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part.
In a specific embodiment of the present invention, its herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part, Asian puccoon 10-15 part, frutus cnidii 10-15 part.
In another embodiment of the present invention, its herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part, Asian puccoon 10-15 part, frutus cnidii 10-15 part, China tree 10-15 part, desmodium 10-15 part, Chinese cassia tree 5-10 part, puncture vine 5-10 part, peppermint 5-10 part, folium eucalypti 5-10 part, goldenrod 5-10 part.
Preferably, its herbal raw material comprises: golden cypress 15 parts, chrysanthemum 15 parts, the coptis 15 parts, Asian puccoon 10 parts, frutus cnidii 10 parts, China tree 10 parts, desmodium 10 parts, Chinese cassia tree 5 parts, puncture vine 5 parts, peppermint 5 parts, folium eucalypti 5 parts, goldenrod 5 parts.
Preferably, its herbal raw material comprises: golden cypress 25 parts, chrysanthemum 25 parts, the coptis 25 parts, Asian puccoon 15 parts, frutus cnidii 15 parts, China tree 15 parts, desmodium 15 parts, Chinese cassia tree 10 parts, puncture vine 10 parts, peppermint 10 parts, folium eucalypti 10 parts, goldenrod 10 parts.
Preferably, its herbal raw material comprises: golden cypress 15 parts, chrysanthemum 25 parts, the coptis 15 parts, Asian puccoon 15 parts, frutus cnidii 10 parts, China tree 15 parts, desmodium 10 parts, Chinese cassia tree 10 parts, puncture vine 5 parts, peppermint 10 parts, folium eucalypti 5 parts, goldenrod 10 parts.
The present invention's object is on the other hand the preparation method providing a kind of antiseptic composition, comprises the steps:
(1) golden cypress, chrysanthemum, the coptis, desmodium are added soak by water 2-3 time of medicinal material weight 8-15 times amount, each 1.5-2 hour, collecting decoction, filters, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod added in the ethanolic solution of 85% of medicinal material weight 8-15 times amount and extract 2-3 time, each 2-3 hour, filters, merging filtrate, reclaims ethanol, obtains filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Preferably, the soak by water 3 times of medicinal material weight 10 times amount is wherein added in step (1), each 1.5 hours; Add in step (2) in the ethanolic solution of 85% of medicinal material weight 10 times amount and extract 3 times, each 3 hours.
Application during the object of third aspect present invention is to provide a kind of antiseptic composition to sterilize in public places, wherein said public place is hospital, kindergarten, school, cinema.
The invention provides a kind of pure antiseptic composition, there is preparation method simple, be easy to suitability for industrialized production, cheap, and have significant bactericidal action to the various common pathogen such as staphylococcus aureus and Candida albicans, sterilizing time is short, and bactericidal effect is good, have no side effect, suitable prolonged application is in the sterilization of the public places such as hospital, kindergarten, school.
Below in conjunction with concrete embodiment, the invention will be further described.
Embodiment
Embodiment 1:
A kind of antiseptic composition, is made up of the herbal raw material of following parts by weight: golden cypress 15 parts, chrysanthemum 15 parts, the coptis 15 parts, Asian puccoon 10 parts, frutus cnidii 10 parts, China tree 10 parts, desmodium 10 parts, Chinese cassia tree 5 parts, puncture vine 5 parts, peppermint 5 parts, folium eucalypti 5 parts, goldenrod 5 parts;
Preparation method is:
(1) golden cypress, chrysanthemum, the coptis, desmodium are added the soak by water 3 times of medicinal material weight 10 times amount, each 1.5 hours, collecting decoction, filtered, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod are added in the ethanolic solution of 85% of medicinal material weight 10 times amount extract 3 times, each 3 hours, filter, merging filtrate, reclaim ethanol, obtain filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Embodiment 2:
A kind of antiseptic composition, is made up of the herbal raw material of following parts by weight: golden cypress 25 parts, chrysanthemum 25 parts, the coptis 25 parts, Asian puccoon 15 parts, frutus cnidii 15 parts, China tree 15 parts, desmodium 15 parts, Chinese cassia tree 10 parts, puncture vine 10 parts, peppermint 10 parts, folium eucalypti 10 parts, goldenrod 10 parts.
Preparation method is:
(1) golden cypress, chrysanthemum, the coptis, desmodium are added the soak by water 2 times of medicinal material weight 8 times amount, each 2 hours, collecting decoction, filtered, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod are added in the ethanolic solution of 85% of medicinal material weight 8 times amount extract 3 times, each 3 hours, filter, merging filtrate, reclaim ethanol, obtain filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Embodiment 3:
A kind of antiseptic composition, is made up of the herbal raw material of following parts by weight: golden cypress 15 parts, chrysanthemum 25 parts, the coptis 15 parts, Asian puccoon 15 parts, frutus cnidii 10 parts, China tree 15 parts, desmodium 10 parts, Chinese cassia tree 10 parts, puncture vine 5 parts, peppermint 10 parts, folium eucalypti 5 parts, goldenrod 10 parts.
(1) golden cypress, chrysanthemum, the coptis, desmodium are added the soak by water 2 times of medicinal material weight 15 times amount, each 1.5 hours, collecting decoction, filtered, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod are added in the ethanolic solution of 85% of medicinal material weight 15 times amount extract 2 times, each 2 hours, filter, merging filtrate, reclaim ethanol, obtain filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Reference examples 1:
A kind of antiseptic composition, is made up of the herbal raw material of following parts by weight: golden cypress 15 parts, chrysanthemum 15 parts, the coptis 15 parts, Asian puccoon 10 parts, frutus cnidii 10 parts, China tree 10 parts, desmodium 10 parts, Chinese cassia tree 5 parts, peppermint 5 parts, folium eucalypti 5 parts;
Preparation method is:
(1) golden cypress, chrysanthemum, the coptis, desmodium are added the soak by water 3 times of medicinal material weight 10 times amount, each 1.5 hours, collecting decoction, filtered, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree are added in the ethanolic solution of 85% of medicinal material weight 10 times amount extract 3 times, each 3 hours, filter, merging filtrate, reclaim ethanol, obtain filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Reference examples 2:
A kind of antiseptic composition, is made up of the herbal raw material of following parts by weight: golden cypress 15 parts, Asian puccoon 10 parts, frutus cnidii 10 parts, China tree 10 parts, desmodium 10 parts, Chinese cassia tree 5 parts, puncture vine 5 parts, peppermint 5 parts, folium eucalypti 5 parts, goldenrod 5 parts;
Preparation method is:
(1) golden cypress, desmodium are added the soak by water 3 times of medicinal material weight 10 times amount, each 1.5 hours, collecting decoction, filtered, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod are added in the ethanolic solution of 85% of medicinal material weight 10 times amount extract 3 times, each 3 hours, filter, merging filtrate, reclaim ethanol, obtain filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
Embodiment 4: bactericidal effect experiment of the present invention
The hospital outpatient transfusion room selecting flow of the people larger is place to use, room height 3.5m, area 45m 2, indoor temperature 23 ~ 26 DEG C, relative moisture 40% ~ 60%.After being closed by door and window, under personnel's proper flow state, use antiseptic composition to add in high-pressure sprayer, spray-on process carries out interior space sterilization.
The antiseptic composition using the embodiment of the present invention 1, reference examples 1, reference examples 2 to prepare respectively carries out disinfection, sampling in latter 60 minutes of sterilizing first 30 minutes and sterilize, and carries out air microbe and cultivates controlled observation Disinfection Effect.Sampling method is, use the Micro-Organism Culture Dish of diameter 90mm, 1 point is respectively got at the heart and four angular distance wall 1m places in a room, height is apart from ground 90cm, and Micro-Organism Culture Dish is exposed in air after 5 minutes, and row microorganism is cultivated, put 37 DEG C of incubators and cultivate 48 hours, statistics clump count.Bacterial inactivation rate is calculated by the regulation in Ministry of Public Health's " hospital disinfection technical specification ".Continuous controlled observation three days, adds up the Disinfection Effect of antiseptic composition of the present invention.
Two, result
Before sterilization, 30min and the rear 60min air microbe cultivation results of sterilization are in table 1.Result shows, antiseptic composition of the present invention is for good to the killing effect of bacterium during spraying disinfection.There is not any bad reaction in on-the-spot crowd, and smell is pure and fresh, can clean air.Also find that the embodiment of the present invention 1 prepares reference examples 1 and the reference examples 2 that disinfectant comparatively omits two taste Chinese herbal medicines by this experiment, Disinfection Effect will be got well.
Table 1 air jet flow microbe colony number result

Claims (10)

1. an antiseptic composition, is characterized in that, its herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part.
2. a kind of antiseptic composition according to claim 1, its herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part, Asian puccoon 10-15 part, frutus cnidii 10-15 part.
3. a kind of antiseptic composition according to claim 1, its herbal raw material comprises: golden cypress 15-25 part, chrysanthemum 15-25 part, coptis 15-25 part, Asian puccoon 10-15 part, frutus cnidii 10-15 part, China tree 10-15 part, desmodium 10-15 part, Chinese cassia tree 5-10 part, puncture vine 5-10 part, peppermint 5-10 part, folium eucalypti 5-10 part, goldenrod 5-10 part.
4. a kind of antiseptic composition according to claim 1, its herbal raw material comprises: golden cypress 15 parts, chrysanthemum 15 parts, the coptis 15 parts, Asian puccoon 10 parts, frutus cnidii 10 parts, China tree 10 parts, desmodium 10 parts, Chinese cassia tree 5 parts, puncture vine 5 parts, peppermint 5 parts, folium eucalypti 5 parts, goldenrod 5 parts.
5. a kind of antiseptic composition according to claim 1, its herbal raw material comprises: golden cypress 25 parts, chrysanthemum 25 parts, the coptis 25 parts, Asian puccoon 15 parts, frutus cnidii 15 parts, China tree 15 parts, desmodium 15 parts, Chinese cassia tree 10 parts, puncture vine 10 parts, peppermint 10 parts, folium eucalypti 10 parts, goldenrod 10 parts.
6. a kind of antiseptic composition according to claim 1, its herbal raw material comprises: golden cypress 15 parts, chrysanthemum 25 parts, the coptis 15 parts, Asian puccoon 15 parts, frutus cnidii 10 parts, China tree 15 parts, desmodium 10 parts, Chinese cassia tree 10 parts, puncture vine 5 parts, peppermint 10 parts, folium eucalypti 5 parts, goldenrod 10 parts.
7. the preparation method of the antiseptic composition described in claim 1-6, is characterized in that comprising the steps:
(1) golden cypress, chrysanthemum, the coptis, desmodium are added soak by water 2-3 time of medicinal material weight 8-15 times amount, each 1.5-2 hour, collecting decoction, filters, obtains filtrate (I) for subsequent use;
(2) Asian puccoon, frutus cnidii, China tree, puncture vine, goldenrod added in the ethanolic solution of 85% of medicinal material weight 8-15 times amount and extract 2-3 time, each 2-3 hour, filters, merging filtrate, reclaims ethanol, obtains filtrate (II) for subsequent use;
(3) Chinese cassia tree cleaned up, peppermint, folium eucalypti are extracted with steam distillation respectively, extract Cortex Cinnamomi volatile oil, Herba Menthae Haplocalycis volatile oil and folium eucalypti volatile oil, mixing, obtains mixture of volatile oil for subsequent use;
(4) by filtrate (I), filtrate (II) mixing, and add the mixture of volatile oil that step (3) obtains, stir, to obtain final product.
8. preparation method according to claim 7, wherein adds the soak by water 3 times of medicinal material weight 10 times amount, each 1.5 hours in step (1); Add in step (2) in the ethanolic solution of 85% of medicinal material weight 10 times amount and extract 3 times, each 3 hours.
9. the antiseptic composition described in claim 1-6 sterilize in public places in application.
10. application according to claim 9, wherein said public place is hospital, kindergarten, school, cinema.
CN201510409526.XA 2015-07-13 2015-07-13 Disinfectant composition Pending CN105010424A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107094807A (en) * 2017-06-05 2017-08-29 太仓优活生物技术有限公司 A kind of harmless disinfectant of Chinese herbal medicine green
CN107668091A (en) * 2017-09-30 2018-02-09 河南科技大学第附属医院 A kind of clinical microbiology laboratory technique Chinese medicine antiseptic and preparation method thereof
CN107853332A (en) * 2017-09-20 2018-03-30 连云港柘达消毒科技有限公司 A kind of environment-friendly high-efficiency disinfectant

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446531A (en) * 2002-03-22 2003-10-08 董景平 Disinfection attendance liquid prepared from Chinese herbal medicine and its production methods
CN101658190A (en) * 2009-08-29 2010-03-03 夏焰明 Liquid preparation with combination of vinegar and air-disinfecting traditional Chinese medicines
CN101692837A (en) * 2009-11-09 2010-04-14 王建国 Pure Chinese medicine disinfectant and process for preparing same
CN103444801A (en) * 2013-08-19 2013-12-18 河北省科学技术情报研究院 Traditional Chinese medicinal bactericidal freshening preparation for sterilizing library

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1446531A (en) * 2002-03-22 2003-10-08 董景平 Disinfection attendance liquid prepared from Chinese herbal medicine and its production methods
CN101658190A (en) * 2009-08-29 2010-03-03 夏焰明 Liquid preparation with combination of vinegar and air-disinfecting traditional Chinese medicines
CN101692837A (en) * 2009-11-09 2010-04-14 王建国 Pure Chinese medicine disinfectant and process for preparing same
CN103444801A (en) * 2013-08-19 2013-12-18 河北省科学技术情报研究院 Traditional Chinese medicinal bactericidal freshening preparation for sterilizing library

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107094807A (en) * 2017-06-05 2017-08-29 太仓优活生物技术有限公司 A kind of harmless disinfectant of Chinese herbal medicine green
CN107853332A (en) * 2017-09-20 2018-03-30 连云港柘达消毒科技有限公司 A kind of environment-friendly high-efficiency disinfectant
CN107668091A (en) * 2017-09-30 2018-02-09 河南科技大学第附属医院 A kind of clinical microbiology laboratory technique Chinese medicine antiseptic and preparation method thereof

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Application publication date: 20151104