CN103493853A - Disinfectant - Google Patents

Abstract

The invention discloses a disinfectant which is a mixture of the following raw materials by weight percent: 60-70 parts of extract of compound Chinese herbal medicines, 1.5-2.5 parts of chlorhexidine acetate, 60-70 parts of ethanol and the balance of water in 100 parts of disinfectant, wherein the compound Chinese herbal medicines comprise the following crude drugs in parts by weight: 20-25 parts of natural chrysanthemum, 10-15 parts of mint, 10-15 parts of root bark of white poplar, 10-15 parts of anemone hupehensis, 15-20 parts of folium isatidis, 15-20 parts of paris polyphylla, 10-15 parts of honeysuckle, 15-20 parts of pine needle, 10-15 parts of cortex dictamni, 7-12 parts of scutellaria baicalensis, 15-20 parts of rhizoma smilacis glabrae, 15-20 parts of fructus cnidii, 7-12 parts of bishopwood, 5-10 parts of hairyvein agrimony and 5-10 parts of cottonrose hibiscus. The disinfectant is reasonable in compatibility of medicines; the effects of clearing away heat and toxic materials, dispelling wind and eliminating dampness and sterilizing can be achieved by cooperative use.

Description

A kind of thimerosal

Technical field

The present invention relates to the thimerosal field, is exactly a kind of thimerosal.

Background technology

Disinfectant refers to for killing pathogenic microorganism on communication media, make it reach the preparation of innoxious requirement, it is different from antibiotic, and its Main Function in diseases prevention is that pathogenic microorganism is eliminated outside human body, cut off the route of transmission of infectious disease, reach the purpose of controlling infectious disease.The normal disinfectant claimed of people refers generally to " chemosterilant ".At present, disinfectant is applied very extensively, not only at medical field, and in our life.Medical disinfecting host commonly used is mainly the type disinfectants such as phenol, aldehyde, alcohol, acid, alkali, chlorinated product, Operand, heavy metal salt, surfactant.The side effects such as these disinfectants exist to some extent contaminated environment, medicament residue, develop immunity to drugs, part belongs to protoplasmic poison, restricted their extensive use.Find environmental sound emphatically and act on disinfectant fast various countries in recent years, wherein with safety, environmental protection, biological disinfectant, more attracts attention.

The generation of the outburst of SARS epidemic situation, H5N1 avian flu cases in recent years and Sichuan violent earthquake in 2008, and novel influenza A virus in 2009 is popular, again the disinfectant industry has been shifted onto to the forefront of epidemic prevention front.Under huge demand promotion, " disinfectant concept " starts completely, and earthquake objectively promotes the disinfectant industry development, and the disinfectant industry presents fast-developing trend.But, when having created unprecedented business opportunity, also stimulate the blindness of Chemistry In China disinfectant enterprise to start and capacity expansion revamping, consequently caused excess production capacity, the market competition aggravation, low in economic efficiency.

The subject matter that current Chinese disinfectant industry exists: the one, number of the enterprise is too many, multi-point and wide-ranging, and layout is unreasonable.The 2nd, enterprise's production scale is little.The annual sales amount of whole nation disinfection drug, medical instruments and amenities enterprise is crossed hundred million yuan, the enterprise of the up to ten million units of profit also with regard to 20 left and right, and the production scale of most enterprises is very little, or even small workshop mode.The 3rd, lack qualified technical personnel.Most enterprises do not have research and development institution.The 4th, production equipment is backward, technique is simple, factory building is simple and crude.At present, the problem that Chinese disinfectant exists aspect product also can not be ignored: the one, and the product development level is low, and kind is single, repetition.The 2nd, the kind of the bulk drug as Main Ingredients and Appearance that the production disinfectant is used is subject to certain limitation.

Summary of the invention

Purpose of the present invention, for existing defect, provides a kind of effective, the thimerosal that the preparation method is easy.

Above-mentioned purpose realizes by following scheme:

A kind of thimerosal, it is characterized in that: it is that raw material by following weight percentage makes: contain following weight portion composition in the thimerosal of its 100 weight portion and mix: the extract of 60-70 part compound Chinese medicine material, chlorhexidine acetate 1.5-2.5, ethanol 60-70, water surplus; In described compound Chinese medicine material, each bulk drug part by weight is: natural bo-chrysanthemum 20-25, peppermint 10-15, david poplar root-bark 10-15, anemone vitifolia 10-15, folium isatidis 15-20, Paris polyphylla 15-20, honeysuckle 10-15, pine needle 15-20, root bark of shaggy-fruited dittany 10-15, root of large-flowered skullcap 7-12, smilax 15-20, frutus cnidii 15-20, eggplant winter root 7-12, hairyvein agrimony 5-10, cotton rose 5-10.

The preparation method of described compound Chinese medicine material water extract comprises the following steps:

Raw material medicaments in part by weight is mixed, add again bulk drug gross weight 6-8 water doubly, decoct to obtain liquid, after filter residue, utilize inorganic ceramic membrane first liquid to be carried out to micro-filtration, then utilize the filter of hollow fiber ultrafiltration membrane essence, the dehydration of recycling NF membrane is concentrated, after collecting the intermembranous thing of 5-20 nanometer, atomized drying and get final product.

Sample of the present invention is through Anhui Chinese Medicine College, Anhui Institute of Medical Sciences, test, detection, checking, analytical proof, not only antibacterial range is wide, speed is fast, and nontoxic, non-stimulated, have no side effect, fully harmless to human body, be very good anti-(pressing down) bacterium amenities of Chinese medicine environmental protection, can be widely used in the anti-antibacterial nursing of various public places, family room, automobile, personal hygiene, medical institutions and human body hand, foot, oral area and other position skin.This product also can be used for oral cavity containing gargling, and effectively prevention of gingivitis, dental plaque and halitosis, as hip bath or flushing, can stop the invasion and attack of various diseases.This environmental protection and human body be there is no to the anti-antibacterial sanitary product of the efficient Chinese medicine environmental protection of a new generation polluted, in 3--5 minute, fungi (mould), Candida albicans, staphylococcus aureus, Escherichia coli, virus and hospital's common pathogen can be killed.The scope of application of the present invention:

1, be applicable to the sterilization of surgery hand and injection site skin;

2, be applicable to multiple place personnel's skin degermings such as hospital, hotel, family, office, tourism;

3, be applicable to the sterilization of the multiple place body surfaces such as hospital, hotel, family, office, tourism;

4, after bite by mosquitos, and cutaneous pruritus.

Using method of the present invention:

1, sterilization before muscle, vein and general skin penetrating: stoste is embrocated 1 time, acts on 1 minute.

2, the sterilization of blood sampling site: stoste is embrocated 1 time, effect 1-2 minute.

3, operative site skin degerming: stoste is embrocated 2 times, effect 2-3 minute.

4, skin and surface disinfection: stoste spraying 1 time, effect 1-2 minute.

Points for attention of the present invention:

1, disinfectant for external use, must not be oral.Be placed in children and be difficult for touching place.

2, to Chlorhexidine, second water allergy sufferers forbidding.

3,, during the operative site skin degerming, if use electric knife, need to be sterilized dose to use after dry.

4, please note after the use and cover tightly bottle cap; Keep away naked light.

5, lucifuge, airtight, In Shade preservation.

Beneficial effect of the present invention is: each compatibility of drugs of the present invention is reasonable, be used in conjunction with can reach clearing heat and detoxicating, dispel rheumatism, the effect of sterilization.

Embodiment

A kind of thimerosal, it is that raw material by following weight percentage makes: contain following weight portion composition in the thimerosal of its 100 gram and mix: the extract of 70 gram compound Chinese medicine materials, chlorhexidine acetate 1.5 grams, ethanol 60 grams, water surplus;

70 gram compound Chinese medicine material Raw medicine part by weight are: natural bo-chrysanthemum 20g, peppermint 10g, david poplar root-bark 12g, anemone vitifolia 10g, folium isatidis 15g, Paris polyphylla 18g, honeysuckle 18g, pine needle 15g, root bark of shaggy-fruited dittany 15g, root of large-flowered skullcap 10g, smilax 15g, frutus cnidii 18g, eggplant winter root 10g, hairyvein agrimony 8g, cotton rose 8g.

The preparation method of described compound Chinese medicine material water extract comprises the following steps:

Raw material medicaments in part by weight is mixed, add again bulk drug gross weight 6-8 water doubly, decoct to obtain liquid, after filter residue, utilize inorganic ceramic membrane first liquid to be carried out to micro-filtration, then utilize the filter of hollow fiber ultrafiltration membrane essence, the dehydration of recycling NF membrane is concentrated, after collecting the intermembranous thing of 5-20 nanometer, atomized drying and get final product.

The product leading indicator is as follows:

1 index

Adopt the methods such as range estimation, nasil to be measured.The organoleptic indicator meets the regulation of table 1.

Table 1 organoleptic indicator

Project	Index
		Smell	There is the distinctive smell of Chinese herbal medicine
Proterties	Liquid, be long placed in and allowed a little precipitation
		Impurity	Cannot see exogenous impurity

2 Biological indicators

Method according to appendix B regulation in GB15979 is measured.It is fixed that microbiological indicator meets table 2

Table 2 microbiological indicator

3 fungistatic effects

Method according to appendix C regulation in GB15979 is measured.The fungistatic effect index meets the regulation of table 3.

Table 3 fungistatic effect index

Project	Index
		The Escherichia coli bacteriostasis rate, %>=	50
The staphylococcus aureus bacteriostasis rate, %>=	50
		White is read the coccus bacteriostasis rate, %>=	50

Claims (2)

1. a thimerosal, it is characterized in that: it is that raw material by following weight percentage makes: contain following weight portion composition in the thimerosal of its 100 weight portion and mix: the extract of 60-70 part compound Chinese medicine material, chlorhexidine acetate 1.5-2.5, ethanol 60-70, water surplus; In described compound Chinese medicine material, each bulk drug part by weight is: natural bo-chrysanthemum 20-25, peppermint 10-15, david poplar root-bark 10-15, anemone vitifolia 10-15, folium isatidis 15-20, Paris polyphylla 15-20, honeysuckle 10-15, pine needle 15-20, root bark of shaggy-fruited dittany 10-15, root of large-flowered skullcap 7-12, smilax 15-20, frutus cnidii 15-20, eggplant winter root 7-12, hairyvein agrimony 5-10, cotton rose 5-10.

2. a kind of thimerosal according to claim 1, it is characterized in that: the preparation method of described compound Chinese medicine material water extract comprises the following steps:

Raw material medicaments in part by weight is mixed, add again bulk drug gross weight 6-8 water doubly, decoct to obtain liquid, after filter residue, utilize inorganic ceramic membrane first liquid to be carried out to micro-filtration, then utilize the filter of hollow fiber ultrafiltration membrane essence, the dehydration of recycling NF membrane is concentrated, after collecting the intermembranous thing of 5-20 nanometer, atomized drying and get final product.