CN103495089A - Rose-scented disinfectant solution capable of effectively killing escherichia coli - Google Patents

Abstract

The invention discloses a rose-scented disinfectant solution capable of effectively killing escherichia coli. The disinfectant solution in 100 parts by weight comprises the following ingredients in parts by weight: 60-70 parts of composite traditional Chinese medicine extract, 1-2 parts of chlorhexidine acetate, 60-70 parts of ethanol and the balance of water, wherein the composite traditional Chinese medicines comprise the following raw herbal materials in parts by weight: 10-15 parts of radix angelicae, 15-20 parts of perilla leaf, 10-15 parts of rheum officinale, 8-12 parts of eutrema yunnanense, 10-15 parts of spica prunellae, 10-15 parts of cassia seed, 8-12 parts of cortex moutan, 8-12 parts of fructus forsythiae, 10-15 parts of sargent gloryvine, 5-8 parts of fallopia japonica, 15-20 parts of purslane, 10-15 parts of herba pyrrosiae, 8-12 parts of willow branch, 10-15 parts of euphorbia hirta L, 5-8 parts of agastache rugosus, 10-15 parts of aster, 5-8 parts of radix stemonae, 8-12 parts of euphorbia formosana hay, 10-15 parts of mint and 1-3 parts of dry rose. The disinfectant solution disclosed by the invention is reasonable in compatibility of medicines and obvious in effect in killing escherichia coli, and due to the adopted dry rose, fragrant rose scent can be given out from the part coated with the disinfectant solution.

Description

A kind ofly effectively kill colibacillary rose scent disinfectant solution

Technical field

The present invention relates to the disinfectant solution field, is exactly a kind of colibacillary rose scent disinfectant solution of effectively killing.

Background technology

Disinfectant refers to for killing pathogenic microorganism on communication media, make it reach the preparation of innoxious requirement, it is different from antibiotic, and its Main Function in diseases prevention is that pathogenic microorganism is eliminated outside human body, cut off the route of transmission of infectious disease, reach the purpose of controlling infectious disease.The normal disinfectant claimed of people refers generally to " chemosterilant ".At present, disinfectant is applied very extensively, not only at medical field, and in our life.Medical disinfecting host commonly used is mainly the type disinfectant such as phenol, aldehyde, alcohol, acid, alkali, chlorinated product, Operand, heavy metal salt, surfactant.The side effect such as these disinfectant exist to some extent contaminated environment, drug residue, develop immunity to drugs, part belongs to protoplasmic poison, restricted their extensive use.Find environmental sound emphatically and act on disinfectant fast various countries in recent years, wherein with safety, environmental protection, biological disinfectant, more attracts attention.

The subject matter that current Chinese disinfectant industry exists: the one, number of the enterprise is too many, multi-point and wide-ranging, and layout is unreasonable.The 2nd, enterprise's production scale is little.The annual sales amount of whole nation disinfection drug, medical instruments and hygienic article enterprise is crossed hundred million yuan, the enterprise of the up to ten million units of profit also with regard to 20 left and right, and the production scale of most enterprises is very little, or even small workshop mode.The 3rd, lack qualified technical personnel.Most enterprises do not have research and development institution.The 4th, production equipment is backward, technique is simple, Factory Building is simple and crude.At present, the problem that Chinese disinfectant exists aspect product also can not be ignored: the one, and the product development level is low, and kind is single, repetition.The 2nd, the kind of the crude drug as Main Ingredients and Appearance that the production disinfectant is used is subject to certain limitation.

Summary of the invention

Purpose of the present invention, for existing defect, provides a kind of effective, and preparation method is easy effectively kills colibacillary rose scent disinfectant solution.

Above-mentioned purpose realizes by following scheme:

A kind ofly effectively kill colibacillary rose scent disinfectant solution, it is characterized in that: contain following weight portion composition in the disinfectant solution of its 100 weight portion and mix: the extract of 60-70 part compound Chinese medicine material, chlorhexidine acetate 1-2, ethanol 60-70, water surplus; In described compound Chinese medicine material, each crude drug weight ratio is: Radix Angelicae Dahuricae 10-15, Folium Perillae 15-20, Radix Et Rhizoma Rhei 10-15, Eutrema yunnanense 8-12, Spica Prunellae 10-15, Semen Cassiae 10-15, Cortex Moutan 8-12, Fructus Forsythiae 8-12, Caulis Sargentodoxae 10-15, Rhizoma Polygoni Cuspidati 5-8, Herba portulacae 15-20, Folium Pyrrosiae 10-15, Ramulus Salicis Babylonicae 8-12, Herba Euphoubiae Hirtae 10-15, Herba Pogostemonis 5-8, Radix Asteris 10-15, Radix Stemonae 5-8, large first grass 8-12, Herba Menthae 10-15, dry Flos Rosae Rugosae 1-3.

Described a kind of colibacillary rose scent disinfectant solution of effectively killing, it is characterized in that: the preparation method of described compound Chinese medicine material water extract comprises the following steps:

(1) weighting raw materials decocts with water secondary after mixing by weight, each 40-50 minute, and the 7-9 that the water yield used is each crude drug gross weight is doubly;

(2) decoction liquor utilizes inorganic ceramic film first medicinal liquid to be carried out to microfiltration, then utilizes the hollow fiber ultrafiltration membrane fine straining, and the dehydration of recycling NF membrane is concentrated, and after collecting the intermembranous thing of 5-20 nanometer, spray drying, obtain.

Sample of the present invention is through Anhui Chinese Medicine College, Anhui Institute of Medical Sciences, test, detection, checking, analytical proof, not only antibacterial range is wide, speed is fast, and nontoxic, non-stimulated, have no side effect, fully harmless to human body, be very good anti-(pressing down) bacterium hygienic article of Chinese medicine environmental protection, can be widely used in the anti-antibacterial nursing of various public places, family room, automobile, Personal hygiene, medical institutions and human body hands, foot, oral area and other position skin.This product also can be used for the oral cavity rinsing the mouth, and effectively prevention of gingivitis, dental plaque and halitosis, as demibain or flushing, can stop the invasion and attack of various diseases.This environmental protection and human body be there is no to the anti-antibacterial sanitary product of the efficient Chinese medicine environmental protection of a new generation polluted, in 3--5 minute, fungus (mycete), Candida albicans, staphylococcus aureus, escherichia coli, virus and hospital's common pathogen can be killed.

Beneficial effect of the present invention is:

Each compatibility of drugs of the present invention is reasonable, is used in conjunction with the effect that can reach heat-clearing and toxic substances removing, expelling wind and removing dampness, anti-inflammation and sterilization, remarkable to killing the escherichia coli effect, adds dry Flos Rosae Rugosae and makes the position of obliterating of the present invention distribute pleasant Rose Essentielle.

The specific embodiment

A kind ofly effectively kill colibacillary rose scent disinfectant solution, contain following weight portion composition in the disinfectant solution of its 100 gram and mix: the extract of 60 gram compound Chinese medicine materials, chlorhexidine acetate 2 grams, ethanol 60 grams, water surplus;

In 60 gram compound Chinese medicine materials, each crude drug weight ratio is: Radix Angelicae Dahuricae 10g, Folium Perillae 15g, Radix Et Rhizoma Rhei 10g, Eutrema yunnanense 8g, Spica Prunellae 10g, Semen Cassiae 10g, Cortex Moutan 10g, Fructus Forsythiae 10g, Caulis Sargentodoxae 12g, Rhizoma Polygoni Cuspidati 7g, Herba portulacae 15g, Folium Pyrrosiae 10g, Ramulus Salicis Babylonicae 10g, Herba Euphoubiae Hirtae 12g, Herba Pogostemonis 7g, Radix Asteris 12g, Radix Stemonae 7g, large first grass 10g, Herba Menthae 12g, dry Flos Rosae Rugosae 30g;

Prepare extract:

(1) take totally 60 gram crude drug and decoct with water secondary after mixing, each 40-50 minute, the 7-9 that the water yield used is each crude drug gross weight is doubly;

(2) decoction liquor utilizes inorganic ceramic film first medicinal liquid to be carried out to microfiltration, then utilizes the hollow fiber ultrafiltration membrane fine straining, and after the dehydration of recycling NF membrane is concentrated, after collecting the intermembranous thing of 5-20 nanometer, spray drying, obtain.

1 organoleptic indicator

Adopt the methods such as range estimation, nasil to be measured.The organoleptic indicator meets the regulation of table 1.

Table 1 organoleptic indicator

2 microbiological indicators

Method according to appendix B regulation in GB15979 is measured.Microbiological indicator meets the regulation of table 4

Table 2 microbiological indicator

Method according to appendix C regulation in GB15979 is measured.The fungistatic effect index meets the regulation of table 3.

Table 3 fungistatic effect index

Project	Index
		The escherichia coli bacteriostasis rate, %>=	50
The staphylococcus aureus bacteriostasis rate, %>=	50
		The Candida albicans bacteriostasis rate, %>=	50

Its escherichia coli bacteriostasis rate reaches 84%, and the staphylococcus aureus bacteriostasis rate reaches 74%, and the Candida albicans bacteriostasis rate reaches 79%.

Claims (2)

1. effectively kill colibacillary rose scent disinfectant solution for one kind, it is characterized in that: contain following weight portion composition in the disinfectant solution of its 100 weight portion and mix: the extract of 60-70 part compound Chinese medicine material, chlorhexidine acetate 1-2, ethanol 60-70, water surplus; In described compound Chinese medicine material, each crude drug weight ratio is: Radix Angelicae Dahuricae 10-15, Folium Perillae 15-20, Radix Et Rhizoma Rhei 10-15, Eutrema yunnanense 8-12, Spica Prunellae 10-15, Semen Cassiae 10-15, Cortex Moutan 8-12, Fructus Forsythiae 8-12, Caulis Sargentodoxae 10-15, Rhizoma Polygoni Cuspidati 5-8, Herba portulacae 15-20, Folium Pyrrosiae 10-15, Ramulus Salicis Babylonicae 8-12, Herba Euphoubiae Hirtae 10-15, Herba Pogostemonis 5-8, Radix Asteris 10-15, Radix Stemonae 5-8, large first grass 8-12, Herba Menthae 10-15, dry Flos Rosae Rugosae 1-3.

2. a kind of colibacillary rose scent disinfectant solution of effectively killing according to claim 1, it is characterized in that: the preparation method of described compound Chinese medicine material water extract comprises the following steps:

(1) weighting raw materials decocts with water secondary after mixing by weight, each 40-50 minute, and the 7-9 that the water yield used is each crude drug gross weight is doubly;

(2) decoction liquor utilizes inorganic ceramic film first medicinal liquid to be carried out to microfiltration, then utilizes the hollow fiber ultrafiltration membrane fine straining, and the dehydration of recycling NF membrane is concentrated, and after collecting the intermembranous thing of 5-20 nanometer, spray drying, obtain.