CN114650883B - 用于检测核酸的测定和方法 - Google Patents

用于检测核酸的测定和方法 Download PDF

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Publication number
CN114650883B
CN114650883B CN202080058836.0A CN202080058836A CN114650883B CN 114650883 B CN114650883 B CN 114650883B CN 202080058836 A CN202080058836 A CN 202080058836A CN 114650883 B CN114650883 B CN 114650883B
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microfluidic cartridge
nucleic acid
amplification
chamber
detection
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CN114650883A (zh
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詹姆斯·保罗·布劳顿
贾斯米特·辛格
克莱尔·路易丝·法兴
玛丽亚-内菲利·察洛格卢
佩德罗·帕特里克·德雷珀·加拉萨
贾尼斯·沙·陈
苗鑫
卢卡斯·哈灵顿
丹尼尔·托马斯·德扎尔
莎拉·简·夏皮罗
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Mammoth Biosciences Inc
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Mammoth Biosciences Inc
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    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
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    • C12Q2521/00Reaction characterised by the enzymatic activity
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    • C12Q2565/00Nucleic acid analysis characterised by mode or means of detection
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/166Oligonucleotides used as internal standards, controls or normalisation probes

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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CN202080058836.0A 2019-06-18 2020-06-17 用于检测核酸的测定和方法 Active CN114650883B (zh)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201962863178P 2019-06-18 2019-06-18
US62/863,178 2019-06-18
US201962879325P 2019-07-26 2019-07-26
US62/879,325 2019-07-26
US201962881809P 2019-08-01 2019-08-01
US62/881,809 2019-08-01
US201962944926P 2019-12-06 2019-12-06
US62/944,926 2019-12-06
US202062985850P 2020-03-05 2020-03-05
US62/985,850 2020-03-05
PCT/US2020/038242 WO2020257356A2 (en) 2019-06-18 2020-06-17 Assays and methods for detection of nucleic acids

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CN114650883A CN114650883A (zh) 2022-06-21
CN114650883B true CN114650883B (zh) 2023-10-27

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US (1) US20220325363A1 (https=)
EP (1) EP3986614A2 (https=)
JP (1) JP2022538046A (https=)
KR (1) KR20220035376A (https=)
CN (1) CN114650883B (https=)
AU (1) AU2020296016A1 (https=)
BR (1) BR112021025669A2 (https=)
CA (1) CA3143685A1 (https=)
IL (1) IL289050A (https=)
MX (1) MX2021016027A (https=)
WO (1) WO2020257356A2 (https=)

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