CN114650814A - 极长链多不饱和脂肪酸、类延长素羟基化衍生物和使用方法 - Google Patents

极长链多不饱和脂肪酸、类延长素羟基化衍生物和使用方法 Download PDF

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Publication number
CN114650814A
CN114650814A CN202080072552.7A CN202080072552A CN114650814A CN 114650814 A CN114650814 A CN 114650814A CN 202080072552 A CN202080072552 A CN 202080072552A CN 114650814 A CN114650814 A CN 114650814A
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elongin
cells
elv
carbon
vlc
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CN202080072552.7A
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English (en)
Chinese (zh)
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里卡多·帕拉西奥斯·佩莱兹
N·G·巴赞
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Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering
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Luis Anna State University Monitoring Committee College Of Agriculture And Mechanical Engineering
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202080072552.7A 2019-09-04 2020-09-04 极长链多不饱和脂肪酸、类延长素羟基化衍生物和使用方法 Pending CN114650814A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962895737P 2019-09-04 2019-09-04
US62/895,737 2019-09-04
US201962923770P 2019-10-21 2019-10-21
US62/923,770 2019-10-21
US201962924359P 2019-10-22 2019-10-22
US62/924,359 2019-10-22
US202062964995P 2020-01-23 2020-01-23
US62/964,995 2020-01-23
PCT/US2020/049541 WO2021046448A1 (en) 2019-09-04 2020-09-04 Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Publications (1)

Publication Number Publication Date
CN114650814A true CN114650814A (zh) 2022-06-21

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CN202080072552.7A Pending CN114650814A (zh) 2019-09-04 2020-09-04 极长链多不饱和脂肪酸、类延长素羟基化衍生物和使用方法

Country Status (9)

Country Link
US (1) US20220339134A1 (https=)
EP (1) EP4025201A4 (https=)
JP (2) JP2022547080A (https=)
CN (1) CN114650814A (https=)
AU (1) AU2020343029A1 (https=)
BR (1) BR112022003985A2 (https=)
CA (1) CA3153088A1 (https=)
MX (1) MX2022002687A (https=)
WO (1) WO2021046448A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4210689A4 (en) * 2020-09-10 2024-11-13 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS, HYDROXYLATED ELOVANOID DERIVATIVES AND METHODS OF USE THEREOF
CN118524834A (zh) * 2021-12-03 2024-08-20 株式会社日水 氧化应激缓和方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107428652A (zh) * 2015-02-09 2017-12-01 路易斯安娜州立大学监测委员会农业和机械学院 用于治疗炎性疾病、退行性疾病和神经退行性疾病的化合物、组合物和方法
WO2018175288A1 (en) * 2017-03-20 2018-09-27 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102256990B (zh) * 2008-10-03 2014-09-24 聚糖生物科学有限责任公司 阴离子寡糖轭合物
US20130190399A1 (en) * 2009-10-31 2013-07-25 Martek Biosciences Corporation Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA)
US20170014365A1 (en) * 2015-07-14 2017-01-19 The Board Of Regents Of The University Of Oklahoma Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use
WO2017077528A2 (en) * 2015-11-02 2017-05-11 Salzman Lovelace Investments, Ltd. Methods and pharmaceutical compositions for treatment of lung inflammation
US20220226270A1 (en) * 2019-04-04 2022-07-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107428652A (zh) * 2015-02-09 2017-12-01 路易斯安娜州立大学监测委员会农业和机械学院 用于治疗炎性疾病、退行性疾病和神经退行性疾病的化合物、组合物和方法
WO2018175288A1 (en) * 2017-03-20 2018-09-27 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KAROLINE KRAUSE 等: "The role of interleukin-1 in allergy-related disorders", 《CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY》, vol. 12, no. 5, pages 477 - 484 *
MOISES A. CALDERON 等: "A comparison of cytokine release from epithelial cells cultured from nasal biopsy specimens of atopic patients with and without rhinitis and nonatopic subjects without rhinitis", 《J ALLERGY CLINIMMUNOL》, vol. 99, no. 1, pages 65 - 76, XP005898988, DOI: 10.1016/S0091-6749(97)70302-6 *

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Publication number Publication date
BR112022003985A2 (pt) 2022-05-24
MX2022002687A (es) 2022-06-16
CA3153088A1 (en) 2021-03-11
EP4025201A1 (en) 2022-07-13
JP2022547080A (ja) 2022-11-10
WO2021046448A1 (en) 2021-03-11
AU2020343029A1 (en) 2022-03-31
JP2025143368A (ja) 2025-10-01
US20220339134A1 (en) 2022-10-27
EP4025201A4 (en) 2023-08-30

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