AU2020343029A1 - Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use - Google Patents

Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use Download PDF

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Publication number
AU2020343029A1
AU2020343029A1 AU2020343029A AU2020343029A AU2020343029A1 AU 2020343029 A1 AU2020343029 A1 AU 2020343029A1 AU 2020343029 A AU2020343029 A AU 2020343029A AU 2020343029 A AU2020343029 A AU 2020343029A AU 2020343029 A1 AU2020343029 A1 AU 2020343029A1
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AU
Australia
Prior art keywords
vlc
carbon
pufa
disease
disclosure
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Pending
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AU2020343029A
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English (en)
Inventor
Nicolas G. Bazan
Ricardo Palacios Pelaez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Louisiana State University
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Louisiana State University
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Publication date
Application filed by Louisiana State University filed Critical Louisiana State University
Publication of AU2020343029A1 publication Critical patent/AU2020343029A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2020343029A 2019-09-04 2020-09-04 Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use Pending AU2020343029A1 (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962895737P 2019-09-04 2019-09-04
US62/895,737 2019-09-04
US201962923770P 2019-10-21 2019-10-21
US62/923,770 2019-10-21
US201962924359P 2019-10-22 2019-10-22
US62/924,359 2019-10-22
US202062964995P 2020-01-23 2020-01-23
US62/964,995 2020-01-23
PCT/US2020/049541 WO2021046448A1 (en) 2019-09-04 2020-09-04 Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Publications (1)

Publication Number Publication Date
AU2020343029A1 true AU2020343029A1 (en) 2022-03-31

Family

ID=74853054

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020343029A Pending AU2020343029A1 (en) 2019-09-04 2020-09-04 Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Country Status (9)

Country Link
US (1) US20220339134A1 (https=)
EP (1) EP4025201A4 (https=)
JP (2) JP2022547080A (https=)
CN (1) CN114650814A (https=)
AU (1) AU2020343029A1 (https=)
BR (1) BR112022003985A2 (https=)
CA (1) CA3153088A1 (https=)
MX (1) MX2022002687A (https=)
WO (1) WO2021046448A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4210689A4 (en) * 2020-09-10 2024-11-13 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College VERY LONG CHAIN POLYUNSATURATED FATTY ACIDS, HYDROXYLATED ELOVANOID DERIVATIVES AND METHODS OF USE THEREOF
CN118524834A (zh) * 2021-12-03 2024-08-20 株式会社日水 氧化应激缓和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102256990B (zh) * 2008-10-03 2014-09-24 聚糖生物科学有限责任公司 阴离子寡糖轭合物
US20130190399A1 (en) * 2009-10-31 2013-07-25 Martek Biosciences Corporation Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA)
JP7025212B2 (ja) * 2015-02-09 2022-02-24 ボード オブ スーパーバイザーズ オブ ルイジアナ ステート ユニバーシティ アンド アグリカルチュアル アンド メカニカル カレッジ 炎症性、変性及び神経変性疾患の治療のための化合物、組成物及び方法
US20170014365A1 (en) * 2015-07-14 2017-01-19 The Board Of Regents Of The University Of Oklahoma Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use
WO2017077528A2 (en) * 2015-11-02 2017-05-11 Salzman Lovelace Investments, Ltd. Methods and pharmaceutical compositions for treatment of lung inflammation
CN110730769A (zh) * 2017-03-20 2020-01-24 路易斯安娜州立大学监测委员会,农业和机械学院 极长链多不饱和脂肪酸、类延长素(elovanoid)羟基化衍生物和使用方法
US20220226270A1 (en) * 2019-04-04 2022-07-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Also Published As

Publication number Publication date
BR112022003985A2 (pt) 2022-05-24
MX2022002687A (es) 2022-06-16
CA3153088A1 (en) 2021-03-11
EP4025201A1 (en) 2022-07-13
JP2022547080A (ja) 2022-11-10
CN114650814A (zh) 2022-06-21
WO2021046448A1 (en) 2021-03-11
JP2025143368A (ja) 2025-10-01
US20220339134A1 (en) 2022-10-27
EP4025201A4 (en) 2023-08-30

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