CN114650813A - 用以治疗视网膜变性的可药化靶标 - Google Patents
用以治疗视网膜变性的可药化靶标 Download PDFInfo
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- CN114650813A CN114650813A CN202080075532.5A CN202080075532A CN114650813A CN 114650813 A CN114650813 A CN 114650813A CN 202080075532 A CN202080075532 A CN 202080075532A CN 114650813 A CN114650813 A CN 114650813A
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- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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| PCT/US2020/050540 WO2021050980A1 (en) | 2019-09-13 | 2020-09-11 | Druggable target to treat retinal degeneration |
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| JP7505912B2 (ja) * | 2020-04-30 | 2024-06-25 | 小林製薬株式会社 | オートファジー活性化剤 |
| WO2022023956A1 (en) * | 2020-07-31 | 2022-02-03 | The Joan and Irwin Jacobs Technion-Cornell Institute | System and method for on-phase microscopy |
| KR102629963B1 (ko) * | 2021-09-23 | 2024-01-29 | 순천향대학교 산학협력단 | mTOR 활성화제를 포함하는 안질환 치료용 조성물 및 이의 용도 |
| CN115969844B (zh) * | 2021-12-28 | 2024-04-02 | 首都医科大学附属北京同仁医院 | Nox2特异性抑制剂在制备视网膜变性药物中的应用 |
| US20250170143A1 (en) * | 2022-04-14 | 2025-05-29 | Mayo Foundation For Medical Education And Research | Methods of treating ocular fibrotic pathologies |
| CN115068456A (zh) * | 2022-05-18 | 2022-09-20 | 中山大学中山眼科中心 | 二甲双胍在制备预防、治疗眼部疾病的药物中的用途及其剂型和制备方法 |
| WO2023229993A1 (en) * | 2022-05-25 | 2023-11-30 | Curative Biotechnology, Inc. | Ophthalmic formulation capable of delivering metformin to choroid rpe and retina |
| KR20230169735A (ko) | 2022-06-09 | 2023-12-18 | 에스케이온 주식회사 | 배터리용 볼트 및 배터리 모듈 |
| WO2024196814A1 (en) | 2023-03-17 | 2024-09-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for treatment of age-related macular degeneration |
| EP4559900A1 (en) * | 2023-11-21 | 2025-05-28 | Opus Genetics, Inc. | Phentolamine mesylate and therapeutic uses thereof |
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| WO2006122249A2 (en) * | 2005-05-11 | 2006-11-16 | Bausch & Lomb Incorporated | Use of plasmin for preventing of reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions |
| US20170042926A1 (en) * | 2014-01-02 | 2017-02-16 | Massachusetts Eye & Ear Infirmary | Treating ocular neovascularization |
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| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| CN1704048A (zh) * | 2004-05-25 | 2005-12-07 | 孙明杰 | 复方羟苯磺酸钙 |
| WO2008022256A2 (en) * | 2006-08-16 | 2008-02-21 | Blagosklonny Mikhail V | Methods and compositions for preventing or treating age-related diseases |
| JP2010047567A (ja) * | 2008-07-24 | 2010-03-04 | Santen Pharmaceut Co Ltd | 加齢黄斑変性の予防又は治療剤 |
| KR101498665B1 (ko) * | 2013-01-10 | 2015-03-05 | 한국 한의학 연구원 | 천연 추출물을 포함하는 당뇨합병증 또는 혈관부종의 예방 또는 치료용 약학적 조성물 및 건강기능식품 조성물 |
| WO2014152661A1 (en) * | 2013-03-14 | 2014-09-25 | Panoptica, Inc. | Ocular formulations for drug-delivery to the posterior segment of the eye |
| CA2976632A1 (en) * | 2015-02-13 | 2016-08-18 | Stealth Biotherapeutics Corp | Therapeutic compositions including mitochondrial fission inhibitor peptides, variants thereof and methods of using the same |
| US20200056186A1 (en) * | 2016-09-22 | 2020-02-20 | Rsem, Limited Partnership | Compositions comprising sasp modulators and senescence attenuators and uses thereof for modulating cellular senescence |
| WO2019033119A1 (en) * | 2017-08-11 | 2019-02-14 | Unity Biotechnology, Inc. | TREATMENT OF OPHTHALMIC CONDITIONS SUCH AS MACULAR DEGENERATION, GLAUCOMA AND DIABETIC RETINOPATHY USING PHARMACEUTICAL AGENTS THAT ELIMINATE SENESCENT CELLS |
| WO2019108602A1 (en) * | 2017-11-28 | 2019-06-06 | University Of Florida Research Foundation | Methods and compositions for retinal drug delivery |
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| WO2006122249A2 (en) * | 2005-05-11 | 2006-11-16 | Bausch & Lomb Incorporated | Use of plasmin for preventing of reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions |
| US20170042926A1 (en) * | 2014-01-02 | 2017-02-16 | Massachusetts Eye & Ear Infirmary | Treating ocular neovascularization |
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| EMILY E. BROWN等: "The Common Antidiabetic Drug Metformin Reduces Odds of Developing Age-Related Macular Degeneration", 《IOVS.ARVOJOURNALS.ORG》, vol. 60, no. 5, pages 1470 - 1477 * |
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Also Published As
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| KR20220070232A (ko) | 2022-05-30 |
| BR112022004515A2 (pt) | 2022-05-31 |
| EP4027985A1 (en) | 2022-07-20 |
| US20220339127A1 (en) | 2022-10-27 |
| AU2020346064A1 (en) | 2022-04-14 |
| WO2021050980A1 (en) | 2021-03-18 |
| MX2022003027A (es) | 2022-06-14 |
| CA3151011A1 (en) | 2021-03-18 |
| JP2022548071A (ja) | 2022-11-16 |
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