MX2022003027A - Diana susceptible a modularse por farmacos para tratar degeneracion retiniana. - Google Patents

Diana susceptible a modularse por farmacos para tratar degeneracion retiniana.

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Publication number
MX2022003027A
MX2022003027A MX2022003027A MX2022003027A MX2022003027A MX 2022003027 A MX2022003027 A MX 2022003027A MX 2022003027 A MX2022003027 A MX 2022003027A MX 2022003027 A MX2022003027 A MX 2022003027A MX 2022003027 A MX2022003027 A MX 2022003027A
Authority
MX
Mexico
Prior art keywords
retinal degeneration
administration
retinal
novel method
treat retinal
Prior art date
Application number
MX2022003027A
Other languages
English (en)
Inventor
Kapil Bharti
Sabanero Karla Yadira Barbosa
Justin Ren Yuan Chang
Balendu Shekhar Jha
Ruchi Sharma
Original Assignee
The Us Secretary Department Of Health & Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Us Secretary Department Of Health & Human Services filed Critical The Us Secretary Department Of Health & Human Services
Publication of MX2022003027A publication Critical patent/MX2022003027A/es

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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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Abstract

Esta invención se refiere a un método novedoso para tratar o mejorar una enfermedad o trastorno retiniano o degradación retiniana en un sujeto y un método novedoso para restaurar las células de epitelio pigmentario retiniano que compromete la administración de uno o más compuestos que modulan Nox4, formación de especies radicales de oxígeno, serina proteasa, un receptor de dopamina, NF-kB, mTOR, AMPK, transición epitelial-mesenquimatosa de RPE, desdiferenciación de RPE, o una o más Rho GTPasas; y kits para la administración de los métodos.
MX2022003027A 2019-09-13 2020-09-11 Diana susceptible a modularse por farmacos para tratar degeneracion retiniana. MX2022003027A (es)

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US201962899899P 2019-09-13 2019-09-13
PCT/US2020/050540 WO2021050980A1 (en) 2019-09-13 2020-09-11 Druggable target to treat retinal degeneration

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MX2022003027A true MX2022003027A (es) 2022-06-14

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JP7505912B2 (ja) 2020-04-30 2024-06-25 小林製薬株式会社 オートファジー活性化剤
US11995833B2 (en) * 2020-07-31 2024-05-28 The Joan and Irwin Jacobs Technion-Cornell Institute System and method for on-phase microscopy
KR102629963B1 (ko) * 2021-09-23 2024-01-29 순천향대학교 산학협력단 mTOR 활성화제를 포함하는 안질환 치료용 조성물 및 이의 용도
CN115969844B (zh) * 2021-12-28 2024-04-02 首都医科大学附属北京同仁医院 Nox2特异性抑制剂在制备视网膜变性药物中的应用
WO2023201312A2 (en) * 2022-04-14 2023-10-19 Mayo Foundation For Medical Education And Research Methods of treating ocular fibrotic pathologies
CN115068456A (zh) * 2022-05-18 2022-09-20 中山大学中山眼科中心 二甲双胍在制备预防、治疗眼部疾病的药物中的用途及其剂型和制备方法
WO2023229993A1 (en) * 2022-05-25 2023-11-30 Curative Biotechnology, Inc. Ophthalmic formulation capable of delivering metformin to choroid rpe and retina
KR20230169735A (ko) 2022-06-09 2023-12-18 에스케이온 주식회사 배터리용 볼트 및 배터리 모듈

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US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US20060257391A1 (en) * 2005-05-11 2006-11-16 Bausch & Lomb Incorporated Non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions
WO2015103480A1 (en) * 2014-01-02 2015-07-09 Massachusetts Eye & Ear Infirmary Treating ocular neovascularization

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BR112022004515A2 (pt) 2022-05-31
US20220339127A1 (en) 2022-10-27
JP2022548071A (ja) 2022-11-16
KR20220070232A (ko) 2022-05-30
AU2020346064A1 (en) 2022-04-14
CN114650813A (zh) 2022-06-21
EP4027985A1 (en) 2022-07-20
WO2021050980A1 (en) 2021-03-18

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