CN114632024A - Refreshing and moisturizing composition containing hydrogenated starch hydrolysate - Google Patents
Refreshing and moisturizing composition containing hydrogenated starch hydrolysate Download PDFInfo
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- CN114632024A CN114632024A CN202210221515.9A CN202210221515A CN114632024A CN 114632024 A CN114632024 A CN 114632024A CN 202210221515 A CN202210221515 A CN 202210221515A CN 114632024 A CN114632024 A CN 114632024A
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- skin
- hydrogenated starch
- starch hydrolysate
- refreshing
- betaine
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- 230000003020 moisturizing effect Effects 0.000 title claims abstract description 72
- 229920001908 Hydrogenated starch hydrolysate Polymers 0.000 title claims abstract description 69
- 239000000203 mixture Substances 0.000 title claims abstract description 43
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 57
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 37
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims abstract description 37
- 229960003237 betaine Drugs 0.000 claims abstract description 37
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- 239000002537 cosmetic Substances 0.000 claims description 18
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- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 4
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- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
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- A61K31/716—Glucans
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A—HUMAN NECESSITIES
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- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
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Abstract
The invention relates to the technical field of skin care, and particularly discloses a refreshing and moisturizing composition containing hydrogenated starch hydrolysate, which is characterized by comprising the following components in percentage by mass: 0.1 to 20.0% hydrogenated starch hydrolysate; 0.1-45.0% betaine; 0.01 to 1.5% of 1, 2-hexanediol; 0.004-1.0% of p-hydroxyacetophenone. The composition has small molecules, is easy to be absorbed by skin, can generate hydrogen bonds with water molecules, and maintains the normal moisture content of the horny layer; meanwhile, the osmotic pressure of the skin stratum corneum is improved, the barrier effect of the skin is enhanced, and the percutaneous water loss effect of the skin is reduced; in addition, the unique composition achieves long-lasting moisturization while having a refreshing pleasant skin feel experience. Solves the problems that the conventional skin moisturizer has good moisturizing effect but sticky and greasy skin feel; the moisturizer having refreshing skin feel has a problem of poor moisturizing effect.
Description
Technical Field
The patent refers to the field of 'cosmetic preparations'.
Background
The skin, as the largest organ of the human body, functions such as: resisting the damage of external environment (such as ultraviolet) to human body; resistance to bacterial virus invasion; regulating body temperature, keeping the internal environment of the human body relatively stable, and the like. The integrity of the skin depends on the relative stability of its composition. Loss of moisture and oil can lead to skin chapping and aging. Moisture retention (water retention) is the most critical component of modern basic skin care. Therefore, how to more effectively retain moisture to the skin becomes a technical difficulty. Most researchers have tried to improve the moisture retention of the skin by using a polyhydric humectant, but the skin feels sticky and greasy due to the polyhydric alcohol humectant, and the feeling of the skin is very heavy, which causes discomfort. In the trend of pursuing a refreshing after-use experience, the invention innovatively discovers that the following composition can achieve a refreshing skin feeling experience and can effectively give a long-acting moistening effect to the skin at the same time.
Disclosure of Invention
One of the objects of the present invention is to provide a refreshing moisturizing composition containing hydrogenated starch hydrolysate for maintaining normal moisture content of skin; meanwhile, the skin barrier effect is enhanced and the percutaneous water loss effect of the skin is reduced by improving the osmotic pressure of the skin stratum corneum, so that the skin is moistened for a long time and has fresh and pleasant skin feeling.
The invention also aims to provide application of the refreshing and moisturizing composition containing the hydrogenated starch hydrolysate in preparation of cosmetics and/or medicines with moisturizing and hydrating effects.
In order to achieve the purpose, the invention adopts the following technical scheme:
a refreshing and moisturizing composition containing hydrogenated starch hydrolysate comprises the following components in percentage by mass:
0.1-20.0% of hydrogenated starch hydrolysate
0.1-45.0% of betaine;
0.01-1.5% of 1, 2-hexanediol;
0.004-1.0% of p-hydroxyacetophenone;
the balance of a cosmetic or dermatologically common external preparation matrix and/or water;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
The composition of the invention moisturizes and moisturizes the stratum corneum of the skin from the following two different directions and simultaneously provides fresh and comfortable moist skin feeling:
1) in the composition of the hydrogenated starch hydrolysate, because a large number of polar groups such as hydroxyl, carboxyl and the like exist in the molecular structure of the hydrogenated starch hydrolysate, hydrogen bonds can be generated with oxygen atoms of water molecules, and the large number of hydrogen bonds restrict the escape and volatilization of the water molecules from liquid, so that the water molecules are mutually restricted to play a role in water retention (moisture retention), and in addition, because the molecular weight of the hydrogenated starch hydrolysate is relatively low, the hydrogenated starch hydrolysate can be limitedly absorbed by skin and enters into the epidermal layer or even the dermis layer of the skin, so that the selective retention of water in the stratum corneum is improved, and the effect of maintaining the normal water content of the stratum corneum for a long time is provided; the skin has moist skin feeling.
2) Betaine is capable of rapidly penetrating into the skin's horny layer (since skin proteins contain a large amount of amide structures and are extremely easily bound thereto) by utilizing the small molecule property of its own amide structure, and is bound to the liquid crystal layer in the horny layer (the liquid crystal layer is a double-layer structure mainly composed of ceramide, fatty acid, and cholesterol). Can form a layer of stable liquid crystal structure through extremely strong hydrogen bonding action of an amide group with lecithin and ceramide; and the hydroxyl at the other end is combined with a large amount of water molecules to form a stable hydration film. Finally, a more stable and water-containing natural structure of 'brick + mud' is formed, and at the same time, the betaine improves the osmotic pressure of the skin stratum corneum, so that the moisture on the skin surface (epidermis) is maintained and the barrier property of the skin is kept; thereby giving the skin a fresh and comfortable feeling.
Through the interaction of the two main components, the amide structure of the betaine assists the hydroxyl carboxyl structure of the hydrogenated starch hydrolysate to quickly enter the skin cuticle for water replenishing and moisture preserving, a composite water replenishing and moisture preserving system is formed, the water replenishing and moisture preserving effect is obvious, the effect is long-lasting, in addition, the amide structure of the 1, 2-hexanediol, the p-hydroxyacetophenone and the betaine and the hydrogenated starch hydrolysate form special fresh and cool lubricating skin feeling, and meanwhile, the corrosion resistance of the system can be ensured.
The hydrogenated starch hydrolysate is prepared by performing enzymatic hydrolysis on starch, decoloring, hydrogenating, removing impurities and concentrating, and the content of the hydrogenated starch hydrolysate is 70-80%. The structure of the skin moisturizing cream belongs to polysaccharide substances containing a plurality of hydroxyl groups, and the skin moisturizing cream has strong hydrophilicity, so that the skin moisturizing cream can balance the secretion of skin grease and improve the smoothness and elasticity of skin.
The betaine is chemically synthesized, has no bound water, and can be used as a humectant and an osmotic pressure regulator. As is well known, water is an essential element of all organisms, and cells are composed of 85-95% water. In water life, water permeates according to active osmolytes, and betaine is a major osmolyte of cells. As a natural osmolyte, betaine has several benefits: 1) does not interfere with the mechanism of the cell; 2) does not disturb the electrostatic balance of the cell; 3) does not affect the structure of the cell. Betaine can protect the metabolic activity in cells and resist the influence of osmotic pressure on cells, and can be used as a carrier of water to keep the water balance of cells.
The invention relates to a refreshing and moisturizing composition containing hydrogenated starch hydrolysate, which is characterized in that the weight part ratio of the hydrogenated starch hydrolysate to the betaine is 3: 8.
1, 2-hexanediol is used as a component for adjusting skin feeling, and can improve the refreshing property and moisturizing effect of skin; at the same time, the system can be provided with anticorrosion performance.
The p-hydroxyacetophenone is also used as a component for regulating skin feel, and can improve the skin refreshing property; at the same time, the system can be provided with anticorrosion performance.
Preferably, the refreshing moisturizing composition containing hydrogenated starch hydrolysate is characterized by comprising the following components in percentage by mass:
1.0-18.0% of hydrogenated starch hydrolysate
3.0-42.0% of betaine;
0.1-1.3% of 1, 2-hexanediol;
0.04-0.8% of p-hydroxyacetophenone;
the balance of a cosmetic or dermatologically common external preparation matrix and/or water;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
More preferably, the hydrogenated starch hydrolysate-containing refreshing and moisturizing composition is characterized by comprising the following components in percentage by mass:
14.0-15.0% of hydrogenated starch hydrolysate
39.0-41.0% of betaine;
0.9-1.1% of 1, 2-hexanediol;
0.3-0.5% of p-hydroxyacetophenone;
the balance of a cosmetic or dermatologically common external preparation matrix and/or water;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
In addition, according to specific efficacy requirements, other corresponding active ingredients can be added into the cosmetics containing the refreshing and moisturizing composition containing the hydrogenated starch hydrolysate to achieve the target effect.
The invention also discloses application of the refreshing and moisturizing composition containing the hydrogenated starch hydrolysate in preparation of cosmetics and/or medicines with moisturizing and hydrating effects.
The refreshing moisturizing composition containing the hydrogenated starch hydrolysate can be directly applied to the skin surface, and can be further used for producing cosmetics to be applied to the skin surface.
The dosage form of the cosmetics and/or the medicines is cream, emulsion, gel or aqua, and can be specifically prepared into products such as emulsion, milky lotion, cream or facial mask and the like.
The invention has the beneficial effects that:
1) in the composition of the hydrogenated starch hydrolysate, because a large number of polar groups such as hydroxyl, carboxyl and the like exist in the molecular structure of the hydrogenated starch hydrolysate, hydrogen bonds can be generated with oxygen atoms of water molecules, and the large number of hydrogen bonds restrict the escape and volatilization of the water molecules from liquid, so that the water molecules are mutually restricted to play a role in water retention (moisture retention), and in addition, because the molecular weight of the hydrogenated starch hydrolysate is relatively low, the hydrogenated starch hydrolysate can be limitedly absorbed by skin and enters into the epidermal layer or even the dermis layer of the skin, so that the selective retention of water in the stratum corneum is improved, and the effect of maintaining the normal water content of the stratum corneum for a long time is provided; the skin has moist skin feeling.
2) Betaine is capable of rapidly penetrating into the skin's horny layer (since skin proteins contain a large amount of amide structures and are extremely easily bound thereto) by utilizing the small molecule property of its own amide structure, and is bound to the liquid crystal layer in the horny layer (the liquid crystal layer is a double-layer structure mainly composed of ceramide, fatty acid, and cholesterol). Can form a layer of stable liquid crystal structure through extremely strong hydrogen bond interaction of an amide group with lecithin and ceramide; and the hydroxyl at the other end is combined with a large amount of water molecules to form a stable hydration film. Finally, a more stable and water-containing natural structure of 'brick + mud' is formed, and at the same time, the betaine improves the osmotic pressure of the skin stratum corneum, so that the moisture on the skin surface (epidermis) is maintained and the barrier property of the skin is kept; thereby giving the skin a fresh and comfortable feeling.
3) Through the interaction of the two main components, the amide structure of the betaine assists the hydroxyl carboxyl structure of the hydrogenated starch hydrolysate to quickly enter the skin cuticle for water replenishing and moisture preserving, a composite water replenishing and moisture preserving system is formed, the water replenishing and moisture preserving effect is obvious, the effect is long-lasting, in addition, the amide structure of the 1, 2-hexanediol, the p-hydroxyacetophenone and the betaine and the hydrogenated starch hydrolysate form special fresh and cool lubricating skin feeling, and meanwhile, the corrosion resistance of the system can be ensured.
Drawings
Fig. 1 is a TEWL line graph of the skin transepidermal water loss profile of comparative experiment one.
Fig. 2 is a line graph showing the change in moisture content of the skin in comparative experiment three.
Detailed Description
The refreshing moisturizing composition containing the hydrogenated starch hydrolysate is prepared by compounding various active ingredients, the amide structure of betaine assists the hydroxyl and carboxyl structures of the hydrogenated starch hydrolysate to rapidly enter the skin cuticle for moisturizing, so that a composite moisturizing system is formed, the moisturizing effect is obvious, the effect is long-lasting, in addition, the amide structure of 1, 2-hexanediol, p-hydroxyacetophenone and betaine and the hydrogenated starch hydrolysate form a special refreshing lubricating skin feel, and the corrosion resistance of the system can be ensured.
The present invention will be described in further detail with reference to specific examples, but the embodiments of the present invention are not limited thereto. A refreshing and moisturizing composition containing hydrogenated starch hydrolysate comprises the following components in percentage by mass:
0.1 to 20.0% of hydrogenated starch hydrolysate
0.1-45.0% of betaine;
0.01-1.5% of 1, 2-hexanediol;
0.004-1.0% of p-hydroxyacetophenone;
the balance of a cosmetic or dermatologically common external preparation matrix and/or water;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine.
In the invention, the other components can be commercial products or can be prepared according to the records of the prior art.
(one) refreshing moisturizing emulsion:
a moisturizing emulsion of a refreshing moisturizing composition containing hydrogenated starch hydrolysate, which comprises the following components in percentage by mass as shown in the following Table 1:
TABLE 1 moisturizing emulsion of refreshing moisturizing composition containing hydrogenated starch hydrolysate
The moisturizing emulsion of the refreshing moisturizing composition containing the hydrogenated starch hydrolysate is prepared by the following steps:
1. respectively heating the phase A and the phase B to 80 ℃, adding the phase B into the phase A, homogenizing uniformly, stirring and cooling;
2. cooling to 40 deg.C, adding hydrogenated starch hydrolysate, betaine, 1, 2-hexanediol, p-hydroxyacetophenone, and antiseptic, and stirring;
3. and finally, adding the phase C, and cooling to 35 ℃ to obtain the moisturizing emulsion.
The composition of the hydrogenated starch hydrolysate was: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol; the appearance is a colorless, viscous, transparent liquid, which is given here by way of example only, without limitation, and the same applies below.
Betaine is anhydrous betaine and is white crystalline powder in appearance, and the method is only exemplary and not limiting.
1, 2-hexanediol is a commercially available product that is a clear liquid in appearance, and is given by way of illustration and not limitation.
P-hydroxyacetophenone is a commercially available product, and is white powder in appearance, which is only an example and is not a limitation, and the following is the same.
Comparative experiment one: transdermal water loss test.
The test selects the refreshing moisturizing emulsions prepared in the above examples 1 and 2, and comparative examples 1 and 2, and verifies whether the products added with the refreshing moisturizing composition containing hydrogenated starch hydrolysate of the present invention have significant moisturizing effect and improve skin function.
1) Test objects: 30 volunteers, female volunteers with an average age of 25.0 years, all skin types were mixed tolerant, no allergic constitution, no skin treatment, cosmetic treatment and other tests that may affect the outcome.
2) The test method comprises the following steps: double blind test: and designating test areas on the inner side of the arm forerunner, and respectively smearing samples to be tested. The sample dosage of each test point is 2mg/cm2. Volunteers washed the inside of the forehand with clear water. After waiting one hour, the skin is tested for baseline (T0). After application of the product, the values of the percutaneous water loss were measured by a Tewameter after one hour (T1), two hours (T2) and three hours (T3) after absorption of the product, and the average of 2 readings was taken as the measurement. The entire test environment was controlled at a temperature of 25 ℃ and a humidity (RH) of 70%. Volunteers were asked to keep the mood level throughout the procedure without touching the test area.
3) Test group: examples 1,2, comparative examples 1,2
4) And (3) testing results: the transdermal water loss variation data (mean values below) were obtained and the test results are shown in fig. 1.
And (4) analyzing results:
the percutaneous water loss (TEWL) data are shown in fig. 1, and the smaller the value of the percutaneous water loss (TEWL) of the stratum corneum measured after the skin is used, the better the barrier function of the skin is, the better the water retention performance is:
as can be seen from fig. 1, after the test samples were applied to the subjects, the TEWL values of the skins of example 1, example 2, comparative example 1 and comparative example 2 were all significantly lower than those recorded before the experiment within 3h of the test period; the moisturizing capability is optimal within 1 hour after the moisturizing lotion is used, and the effects of the moisturizing lotion in the examples 1 and 2 are superior to those of the moisturizing lotion in the comparative examples 1 and 2, so that the moisturizing lotion is obvious in effect of inhibiting water loss, is beneficial to fully moisturizing skin, and is more obvious in effect when the moisturizing lotion is added.
Comparative experiment two: evaluation of skin-refreshing property.
The test uses the refreshing moisturizing emulsions prepared in examples 1 and 2, and comparative examples 1 and 2 to verify whether the products containing the refreshing moisturizing composition containing hydrogenated starch hydrolysate of the present invention have a significant post-consumer refreshing and comfortable skin feel experience.
1) Test objects: 30 volunteers, female volunteers with the average age of 25.0 years, were trained by professionals and then tested, and the test subjects had no history of skin diseases, the tested parts were normal, and no drug or cosmetic which is irrelevant to the test was smeared during the test period.
2) The test method comprises the following steps: before the test, the subjects clean the faces through tap water at 36 +/-2 ℃, the samples of example 1, example 2, comparative example 1 and comparative example 2 are taken as the samples respectively to carry out the experiment, one group of the samples is selected to carry out the experiment, the emulsions of example 1, example 2, comparative example 1 and comparative example 2 are used for the skin care step after the face cleaning, the blank control group does not use any skin care products after the face cleaning, and the test results are shown in a table 2.
3) Test group: example 1, example 2, comparative example 1, comparative example 2.
4) And (3) testing results: after the test sample is used, the smeared test sample is evaluated according to sensory experience, description results similar to the sensory experience are selected, induction statistics is carried out, and specific test results are shown in table 2.
Table 2 evaluation of skin feel refreshment after use of each example and comparative example:
from the results of table 2, it can be seen that: the refreshing feeling of example 1 was considered to be good by 96.7% of experimenters, and the refreshing feeling after skin care was considered to be general by 3.3% of experimenters; the refreshing feeling after skin care of example 2 was considered to be good by 76.7% of the experimenters, and the refreshing feeling after skin care of the emulsion of example 2 was considered to be general by 23.3% of the experimenters; the refreshing feeling after skin care of comparative example 1 was considered to be good by 36.7% of experimenters, the refreshing feeling after skin care of comparative example 1 was considered to be general by 60.0% of experimenters, and the refreshing feeling after skin care of comparative example 1 was considered not to be good by 3.3% of experimenters. The refreshing feeling after skin care of comparative example 2 was considered to be general by 73.3% of the experimenters, and the refreshing feeling after skin care of comparative example 2 was considered not good by 26.7% of the experimenters.
The above experimental results show that: the moisturizing cream has good moisturizing and hydrating effects and excellent refreshing skin feeling experience after use.
(II) refreshing and moisturizing water:
a moisturizing lotion of a refreshing moisturizing composition containing hydrogenated starch hydrolysate comprises the following components in percentage by mass:
table 3 moisturizing lotion of a refreshing moisturizing composition containing hydrogenated starch hydrolysate:
the moisturizing water of the refreshing moisturizing composition containing the hydrogenated starch hydrolysate is prepared by the following steps:
1. uniformly mixing the phase A, heating to 80 ℃, keeping the temperature for 30 minutes until the system is completely dissolved, and stirring and cooling;
2. cooling to 40 deg.C, adding hydrogenated starch hydrolysate, betaine, 1, 2-hexanediol, p-hydroxyacetophenone, and antiseptic, and stirring; 3. finally, stirring to normal temperature and discharging.
The composition of the hydrogenated starch hydrolysate was: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol; the appearance is a colorless, viscous, transparent liquid, which is given here by way of example only, without limitation, and the same applies below.
Betaine is anhydrous betaine and is white crystalline powder in appearance, and the method is only exemplary and not limiting.
1, 2-hexanediol is a commercially available product that is a clear liquid in appearance, and is given by way of illustration and not limitation.
P-hydroxyacetophenone is a commercially available product, and is white powder in appearance, which is only an example and is not a limitation, and the following is the same.
A third comparative experiment: testing water replenishing and moisture preserving performance:
1) test object(s): 30 volunteers, female volunteers with an average age of 25.0 years, all skin types were mixed tolerant, no allergic constitution, no skin treatment, cosmetic treatment and other tests that may affect the outcome.
2) The test method comprises the following steps: the volunteers respectively draw 5 pieces of 2cm on the left and right arms in an indoor environment with the temperature of 25 ℃ and the relative humidity of 70 percent2At a fixed area of 0.5g/cm2The moisturizing liquids obtained in example 3, comparative example 4, comparative example 5 and comparative example 6 were used in a fixed area, and the skin moisture change data (the values below are average values) were obtained by a Corneometer CM285 skin moisture meter.
3) Test group: example 3, comparative example 4, comparative example 5, comparative example 6.
4) The test results are shown in FIG. 2:
and (4) analyzing results:
the moisture content data of the skin stratum corneum is shown in fig. 2, and the higher the moisture content of the skin stratum corneum measured after the product is used, the better the moisturizing effect of the product is.
As can be seen from the data in FIG. 2, the skin moisture content of example 3 is higher than that of comparative examples 3-6, and the results prove that when the components are reasonably compounded for use, the effect is superior to that of any one of the components when used alone, the moisturizing effect is remarkably improved, and the use amount of each component can be lower than that when used alone during compounding.
And a fourth comparative experiment: evaluation of skin-refreshing property.
The test uses the refreshing moisturizing water of the above examples 3, 4, 5, 6 to verify whether the products to which the refreshing moisturizing composition containing hydrogenated starch hydrolysate of the present invention is added have a significant post-use refreshing comfortable skin feel experience.
1) Test objects: 30 volunteers, female volunteers with the average age of 25.0 years, were trained by professionals and tested, and the subjects had no history of skin diseases, the tested parts were normal, and no drug or cosmetic which is irrelevant to the test was smeared during the test period.
2) The test method comprises the following steps: before the test, the subjects clean the faces through tap water at 36 +/-2 ℃, the samples of example 3, comparative example 4, comparative example 5 and comparative example 6 are taken to carry out the experiment, one group of samples are taken to carry out the experiment, the moisturizing water of example 3, comparative example 4, comparative example 5 and comparative example 6 is used for the skin care step after the face is cleaned, the blank control group does not use any skin care product after the face is cleaned, and the test results are shown in table 2.
3) Test group: example 3, comparative example 4, comparative example 5, comparative example 6.
4) And (3) testing results: after the test sample is used, the smeared test sample is evaluated according to sensory experience, description results similar to the sensory experience are selected, induction statistics is carried out, and specific test results are shown in table 4.
Table 4 evaluation of skin feel refreshment after use of the examples and comparative examples:
from the results of table 4, it can be seen that: the refreshing feeling of example 3 was considered to be good by 100% of experimenters; 63.3% of the experimenters considered the refreshing feeling after skin care of comparative example 3 to be general, and 36.7% of the experimenters considered the refreshing feeling after skin care of comparative example 3 to be poor; the refreshing feeling after skin care of comparative example 4 was considered to be good by 26.7% of the experimenters, and the refreshing feeling after skin care of comparative example 4 was considered to be general by 73.3% of the experimenters; the refreshing feeling after the skin care of the comparative example 5 was considered to be good by 16.7% of the experimenters, and the refreshing feeling after the skin care of the comparative example 5 was considered to be general by 83.3% of the experimenters; the refreshing feeling after the skin care of comparative example 6 was considered good by 53.3% of the experimenters, and the refreshing feeling after the skin care of comparative example 6 was considered general by 46.7% of the experimenters.
The above experimental results show that: example 3 had an excellent refreshing skin feel experience after use.
In summary, the data from the four comparative experiments described above can demonstrate that: the components of the hydrogenated starch hydrolysate, the betaine, the 1, 2-hexanediol and the p-hydroxyacetophenone in the refreshing and moisturizing composition containing the hydrogenated starch hydrolysate provided by the invention are combined with each other to achieve a synergistic effect, so that the composition has good moisturizing performance, can be used for lasting moisturizing, can protect the skin, inhibit the water loss and simultaneously can provide a very refreshing after-use experience for a user.
In conclusion, it is intended that the foregoing detailed description be regarded as illustrative rather than limiting, and that it be understood that it is illustrative only and is not intended to limit the scope of the invention. After reading the description of the present invention, the skilled person can make various changes or modifications to the invention, and these equivalent changes and modifications also fall into the scope of the invention defined by the claims.
Claims (6)
1. A refreshing moisturizing composition containing hydrogenated starch hydrolysate, which is characterized by comprising the following components in percentage by mass:
0.1 to 20.0% of hydrogenated starch hydrolysate
0.1-45.0% of betaine;
0.01-1.5% of 1, 2-hexanediol;
0.004-1.0% of p-hydroxyacetophenone;
the balance of a cosmetic or dermatologically common external preparation matrix and/or water;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
2. The hydrogenated starch hydrolysate-containing refreshing moisturizing composition according to claim 1, wherein the skin moisturizing composition is characterized by comprising the following components in percentage by mass:
1.0-18.0% of hydrogenated starch hydrolysate
3.0-42.0% of betaine;
0.1-1.3% of 1, 2-hexanediol;
0.04-0.8% of p-hydroxyacetophenone;
the balance of a base and/or water for external preparation commonly used in cosmetics or dermatology;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
3. The hydrogenated starch hydrolysate-containing refreshing moisturizing composition according to claim 2, wherein the skin moisturizing composition is characterized by comprising the following components in percentage by mass:
14.0 to 15.0 percent of hydrogenated starch hydrolysate
39.0-41.0% of betaine;
0.9-1.1% of 1, 2-hexanediol;
0.3-0.5% of p-hydroxyacetophenone;
the balance of a base and/or water for external preparation commonly used in cosmetics or dermatology;
the hydrogenated starch hydrolysate comprises the following components: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
4. The hydrogenated starch hydrolysate-containing refreshing moisturizing composition according to claims 1 to 3, wherein the composition of the hydrogenated starch hydrolysate is: maltopentaol, maltotetraol, maltotriol, maltodiol, sorbitol;
the betaine is anhydrous betaine and does not contain crystal water.
5. The hydrogenated starch hydrolysate-containing refreshing and moisturizing composition according to claim 4, wherein the weight percentage ratio of the hydrogenated starch hydrolysate to the betaine is 3: 8.
6. use of the refreshing moisturizing composition comprising hydrogenated starch hydrolysate according to any one of claims 1 to 3 in cosmetics and/or pharmaceuticals for moisturizing and hydrating.
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