CN114540470B - 用于次要等位基因和多态性的鉴定和定量的多重化方法 - Google Patents

用于次要等位基因和多态性的鉴定和定量的多重化方法

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Publication number
CN114540470B
CN114540470B CN202210143725.0A CN202210143725A CN114540470B CN 114540470 B CN114540470 B CN 114540470B CN 202210143725 A CN202210143725 A CN 202210143725A CN 114540470 B CN114540470 B CN 114540470B
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nucleic acid
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specific
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CN114540470A (zh
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A·O·H·尼格伦
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Agena Bioscience Inc
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Agena Bioscience Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN202210143725.0A 2015-04-24 2016-04-22 用于次要等位基因和多态性的鉴定和定量的多重化方法 Active CN114540470B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562152697P 2015-04-24 2015-04-24
US62/152,697 2015-04-24
US201662280951P 2016-01-20 2016-01-20
US62/280,951 2016-01-20
CN201680013462.4A CN107406882B (zh) 2015-04-24 2016-04-22 用于次要等位基因和多态性的鉴定和定量的多重化方法
PCT/US2016/028971 WO2016172571A1 (en) 2015-04-24 2016-04-22 Multiplexed method for the identification and quantitation of minor alleles and polymorphisms

Related Parent Applications (1)

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CN201680013462.4A Division CN107406882B (zh) 2015-04-24 2016-04-22 用于次要等位基因和多态性的鉴定和定量的多重化方法

Publications (2)

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CN114540470A CN114540470A (zh) 2022-05-27
CN114540470B true CN114540470B (zh) 2026-01-30

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Country Link
US (5) US10233489B2 (enExample)
EP (2) EP4001430A1 (enExample)
JP (5) JP2018512880A (enExample)
CN (2) CN114540470B (enExample)
AU (1) AU2016250841A1 (enExample)
CA (1) CA2983224A1 (enExample)
HK (1) HK1250747A1 (enExample)
WO (1) WO2016172571A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110564819A (zh) 2011-05-19 2019-12-13 基纳生物技术有限公司 用于多重核酸鉴定的产品和方法
JP2018512880A (ja) 2015-04-24 2018-05-24 アジーナ バイオサイエンス， インコーポレイテッド 少量の対立遺伝子および多型の同定ならびに定量のためのマルチプレックス法
CN107787371B (zh) 2015-04-24 2022-02-01 基纳生物技术有限公司 检测和定量次要变体的并行式方法
EP3802867A1 (en) 2018-06-01 2021-04-14 Agena Bioscience, Inc. Products and processes for nucleic acid detection and quantification
CN113466320B (zh) * 2021-08-06 2022-10-14 河北省食品检验研究院 一种针对乳粉中牛源性成分maldi-tof检测方法
KR102857507B1 (ko) * 2022-11-14 2025-09-10 명지대학교 산학협력단 무의 근피 색상 판별용 snp 마커 및 이의 용도
US12518859B2 (en) * 2023-07-26 2026-01-06 Helix, Inc. Systems and methods for providing test results of gene sequencing data on a recurring basis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103717751A (zh) * 2011-05-19 2014-04-09 塞昆纳姆股份有限公司 用于多重核酸鉴定的产品和方法

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CN107406882B (zh) 2022-03-01
JP2021097718A (ja) 2021-07-01
CN107406882A (zh) 2017-11-28
EP3286327A1 (en) 2018-02-28
JP2019083820A (ja) 2019-06-06
CN114540470A (zh) 2022-05-27
US20190153526A1 (en) 2019-05-23
US10513728B2 (en) 2019-12-24
AU2016250841A1 (en) 2017-11-02
US10865439B2 (en) 2020-12-15
US20210062254A1 (en) 2021-03-04
HK1250747A1 (zh) 2019-01-11
JP2018512880A (ja) 2018-05-24
EP3286327B1 (en) 2021-11-10
CA2983224A1 (en) 2016-10-27
US11680289B2 (en) 2023-06-20
JP2024012522A (ja) 2024-01-30
US20200123601A1 (en) 2020-04-23
US20230383340A1 (en) 2023-11-30
US20160312278A1 (en) 2016-10-27
WO2016172571A1 (en) 2016-10-27
US10233489B2 (en) 2019-03-19
US12454722B2 (en) 2025-10-28
EP4001430A1 (en) 2022-05-25
JP7325467B2 (ja) 2023-08-14
JP2021097719A (ja) 2021-07-01

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