CN114146035B - Sun-proof anti-aging face cream and preparation method thereof - Google Patents
Sun-proof anti-aging face cream and preparation method thereof Download PDFInfo
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- 239000006071 cream Substances 0.000 title claims abstract description 61
- 230000003712 anti-aging effect Effects 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 93
- 239000012071 phase Substances 0.000 claims abstract description 74
- -1 hexyl methoxycinnamate acetate Chemical compound 0.000 claims abstract description 61
- 108010016626 Dipeptides Proteins 0.000 claims abstract description 35
- 150000001408 amides Chemical class 0.000 claims abstract description 26
- 235000005770 birds nest Nutrition 0.000 claims abstract description 23
- 235000005765 wild carrot Nutrition 0.000 claims abstract description 23
- 244000000626 Daucus carota Species 0.000 claims abstract description 20
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 claims abstract description 13
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 claims abstract description 13
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 claims abstract description 13
- 239000008346 aqueous phase Substances 0.000 claims abstract description 12
- 230000001815 facial effect Effects 0.000 claims abstract description 7
- 238000009472 formulation Methods 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 239000013011 aqueous formulation Substances 0.000 claims abstract description 4
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 77
- 229920002125 Sokalan® Polymers 0.000 claims description 77
- 229960001631 carbomer Drugs 0.000 claims description 77
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 70
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 63
- 239000004205 dimethyl polysiloxane Substances 0.000 claims description 56
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims description 56
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims description 56
- 239000003921 oil Substances 0.000 claims description 43
- 235000019198 oils Nutrition 0.000 claims description 43
- 239000008367 deionised water Substances 0.000 claims description 30
- 229910021641 deionized water Inorganic materials 0.000 claims description 30
- PFHLGILELJGQSJ-UHFFFAOYSA-N 4-(2h-benzotriazol-4-ylmethyl)-2h-benzotriazole;2-butyl-3,4,5,6-tetramethylphenol Chemical compound CCCCC1=C(C)C(C)=C(C)C(C)=C1O.C=1C=CC=2NN=NC=2C=1CC1=CC=CC2=C1N=NN2 PFHLGILELJGQSJ-UHFFFAOYSA-N 0.000 claims description 29
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 28
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims description 28
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims description 28
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 28
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims description 28
- 235000021355 Stearic acid Nutrition 0.000 claims description 28
- 229960003237 betaine Drugs 0.000 claims description 28
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims description 28
- 239000002285 corn oil Substances 0.000 claims description 28
- 235000005687 corn oil Nutrition 0.000 claims description 28
- 229920006037 cross link polymer Polymers 0.000 claims description 28
- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 claims description 28
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 claims description 28
- 235000011187 glycerol Nutrition 0.000 claims description 28
- 229940105132 myristate Drugs 0.000 claims description 28
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims description 28
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 28
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 28
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims description 28
- 229960005323 phenoxyethanol Drugs 0.000 claims description 28
- 229940069338 potassium sorbate Drugs 0.000 claims description 28
- 235000010241 potassium sorbate Nutrition 0.000 claims description 28
- 239000004302 potassium sorbate Substances 0.000 claims description 28
- 229940032094 squalane Drugs 0.000 claims description 28
- 239000008117 stearic acid Substances 0.000 claims description 28
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 claims description 28
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 28
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims description 28
- 229920002554 vinyl polymer Polymers 0.000 claims description 28
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 27
- 239000000839 emulsion Substances 0.000 claims description 24
- 238000001816 cooling Methods 0.000 claims description 22
- 238000010438 heat treatment Methods 0.000 claims description 20
- FQEDESWDVHAQBG-UHFFFAOYSA-N hexyl 2-methoxy-3-phenylprop-2-enoate Chemical compound CCCCCCOC(=O)C(OC)=CC1=CC=CC=C1 FQEDESWDVHAQBG-UHFFFAOYSA-N 0.000 claims description 14
- 239000000516 sunscreening agent Substances 0.000 claims description 14
- 238000003756 stirring Methods 0.000 claims description 13
- 230000000475 sunscreen effect Effects 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 11
- 229940094541 polyglycerin-10 Drugs 0.000 claims description 11
- RJZNPROJTJSYLC-LLINQDLYSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O RJZNPROJTJSYLC-LLINQDLYSA-N 0.000 claims description 4
- 241000972673 Phellodendron amurense Species 0.000 claims description 3
- 230000001105 regulatory effect Effects 0.000 claims description 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 9
- 230000032683 aging Effects 0.000 abstract description 7
- 239000003205 fragrance Substances 0.000 abstract description 2
- FQUNFJULCYSSOP-UHFFFAOYSA-N bisoctrizole Chemical compound N1=C2C=CC=CC2=NN1C1=CC(C(C)(C)CC(C)(C)C)=CC(CC=2C(=C(C=C(C=2)C(C)(C)CC(C)(C)C)N2N=C3C=CC=CC3=N2)O)=C1O FQUNFJULCYSSOP-UHFFFAOYSA-N 0.000 abstract 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 48
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 18
- 230000037303 wrinkles Effects 0.000 description 14
- 210000003491 skin Anatomy 0.000 description 13
- 238000012360 testing method Methods 0.000 description 12
- CNXZMGRWEYQCOQ-UHFFFAOYSA-N 2-methoxy-3-phenylprop-2-enoic acid Chemical compound COC(C(O)=O)=CC1=CC=CC=C1 CNXZMGRWEYQCOQ-UHFFFAOYSA-N 0.000 description 10
- AOGQPLXWSUTHQB-UHFFFAOYSA-N hexyl acetic acid ester Natural products CCCCCCOC(C)=O AOGQPLXWSUTHQB-UHFFFAOYSA-N 0.000 description 10
- 150000001412 amines Chemical class 0.000 description 7
- 238000004090 dissolution Methods 0.000 description 7
- 238000002835 absorbance Methods 0.000 description 6
- 230000001153 anti-wrinkle effect Effects 0.000 description 6
- 238000012216 screening Methods 0.000 description 6
- 230000000052 comparative effect Effects 0.000 description 5
- NCIAZCLIFWUDPR-UHFFFAOYSA-N 2-butyl-3,4,5,6-tetramethylphenol Chemical compound CCCCC1=C(C)C(C)=C(C)C(C)=C1O NCIAZCLIFWUDPR-UHFFFAOYSA-N 0.000 description 4
- BPGUKNRILVZFIA-UHFFFAOYSA-N 4-(2h-benzotriazol-4-ylmethyl)-2h-benzotriazole Chemical compound C=1C=CC=2NN=NC=2C=1CC1=CC=CC2=C1N=NN2 BPGUKNRILVZFIA-UHFFFAOYSA-N 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 4
- 229940008099 dimethicone Drugs 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 230000007830 nerve conduction Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 230000037072 sun protection Effects 0.000 description 3
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 206010040914 Skin reaction Diseases 0.000 description 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 2
- 229960004373 acetylcholine Drugs 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 125000005456 glyceride group Chemical group 0.000 description 2
- 230000036074 healthy skin Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 230000035483 skin reaction Effects 0.000 description 2
- 231100000430 skin reaction Toxicity 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000016942 Elastin Human genes 0.000 description 1
- 108010014258 Elastin Proteins 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 239000002390 adhesive tape Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000009982 effect on human Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 229920002549 elastin Polymers 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000245 forearm Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
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- 230000009759 skin aging Effects 0.000 description 1
- 201000000849 skin cancer Diseases 0.000 description 1
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- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 239000003998 snake venom Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/981—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to a sun-proof anti-aging facial cream and a preparation method thereof, wherein the facial cream comprises the following components: an aqueous phase formula, an oil phase formula, acetyl hexapeptide-8, a bird's nest extract, a cortex phellodendri extract and citric acid; the aqueous formulation includes a dipeptide diamino Ding Xianbian-based amide diacetate; the oil phase formulation included methylene bis-benzotriazolyl tetramethylbutylphenol and hexyl methoxycinnamate acetate. The face cream prepared by the invention is mild and comfortable, harmonious and natural in fragrance, has the sun-proof effect while resisting aging, and is low in cost.
Description
Technical Field
The invention belongs to the field of cosmetics, and particularly relates to sun-proof anti-aging face cream and a preparation method thereof.
Background
The solar spectrum can be roughly divided into three parts: ultraviolet (wavelength 200-400 mm), visible (wavelength 400-800 nm) and infrared (800-1 mm). Ultraviolet light is only a small fraction (5%) of sunlight, but this small fraction is also sufficient to have some effect on human health, and light skin tanning, sun-drying and sunburn, severe and even skin cancer can result. Existing sun protection products often do not have anti-aging effects.
One of the main causes of skin aging is the altered structure of the dermis layer. There are various causes of the change in the dermal structure of the skin, such as skin inflammatory reaction, oxidation reaction, loss of skin moisture, etc.
The existing anti-aging skin care product added with the antioxidant has the problems of poor permeability, difficult absorption, unobvious anti-wrinkle effect, repeated occurrence of wrinkles, allergy and the like.
Thus, there is a need for a face cream that combines sun protection and anti-aging.
Disclosure of Invention
In view of the above problems, the present invention provides a sunscreen anti-aging facial cream comprising the following components:
an aqueous phase formula, an oil phase formula, acetyl hexapeptide-8, a bird's nest extract, a cortex phellodendri extract and citric acid;
the aqueous formulation includes a dipeptide diamino Ding Xianbian-based amide diacetate;
the oil phase formulation includes methylenebis-benzotriazole tetramethylbutylphenol and hexyl methoxycinnamate acetate.
Further, the method comprises the steps of,
the aqueous phase formula also comprises glycerin, betaine, butanediol, 1, 2-pentanediol, potassium sorbate, carbomer and deionized water;
the oil phase formulation also includes vinyl dimethicone cross-linked polymer, dimethicone, polyglycerin-10 myristate, stearic acid, mono-di glyceride, tocopheryl acetate, squalane, phenoxyethanol, white pool seed oil, and corn oil.
Further, the face cream comprises the following components in percentage by mass:
66.397-89.499% of water phase formula, 8.1-28.1% of oil phase formula, 80.5-2% of acetyl hexapeptide, 0.2-1% of bird's nest extract, 0.2-1% of cortex phellodendri extract and 0.001-0.003% of citric acid;
the aqueous phase formula comprises 2-5% of dipeptide diamino Ding Xianbian-base amide diacetate;
the oil phase formula comprises 0.2-1% of methylene bis-benzotriazole tetramethyl butyl phenol and 0.1-0.5% of methoxy cinnamic acid hexyl acetate.
Further, the water phase formula also comprises 3-8% of glycerin, 2-6% of betaine, 2-6% of butanediol, 2-5% of 1, 2-pentanediol, 0.1-0.5% of potassium sorbate, 3.5-8.5% of carbomer gel and 28.897-75.399% of deionized water according to mass percentage;
the oil phase formula also comprises 2-6% of vinyl polydimethylsiloxane crosslinked polymer, 1-6% of polydimethylsiloxane, 1-3% of polyglycerol-10 myristate, 1-3% of stearic acid, 1-3% of mono-diglyceride, 0.5-2% of tocopheryl acetate, 0.5-1% of squalane, 0.5-1% of phenoxyethanol, 0.1-0.8% of white pool seed oil and 0.2-0.8% of corn oil.
Further, the face cream comprises the following components in percentage by mass:
glycerol 6%, betaine 5%, carbomer 5%, dipeptide diamino Ding Xianbian-based amide diacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pool flower seed oil 0.5%, corn oil 0.5%, phellodendron bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.4% and citric acid 0.001%, the balance being ionized water;
the carbomer gel is prepared by adding carbomer with the mass percentage of 5% into deionized water, and adjusting the pH to 8-9 by using 1.2% of triethanolamine.
The invention also provides a preparation method of the sun-proof anti-aging facial cream, which comprises the following steps:
adding carbomer into deionized water, and regulating the pH to 8-9 by using triethanolamine to prepare carbomer gel;
adding the aqueous phase formula into the carbomer gel, homogenizing and dispersing, and heating for later use; the aqueous formulation includes a dipeptide diamino Ding Xianbian-based amide diacetate;
mixing the oil phase formula, heating and dissolving; the oil phase formulation comprises methylene bis-benzotriazole tetramethylbutylphenol and hexyl methoxycinnamate acetate;
adding the oil phase formula into the water phase formula, stirring uniformly under heating, and homogenizing and dispersing to obtain a mixed emulsion;
and (3) cooling the mixed emulsion for the first time, adding acetyl hexapeptide-8, bird nest extract, cortex phellodendri extract and citric acid, homogenizing and dispersing uniformly, and cooling to room temperature for the second time to obtain the sun-proof anti-aging face cream.
Further, the method comprises the steps of,
the face cream comprises the following components in percentage by mass:
66.397-89.499% of water phase formula, 8.1-28.1% of oil phase formula, 80.5-2% of acetyl hexapeptide, 0.2-1% of bird's nest extract, 0.2-1% of cortex phellodendri extract and 0.001-0.003% of citric acid;
the aqueous phase formula comprises 2-5% of dipeptide diamino Ding Xianbian-base amide diacetate;
the oil phase formula comprises 0.2-1% of methylene bis-benzotriazole tetramethyl butyl phenol and 0.1-0.5% of methoxy cinnamic acid hexyl acetate.
Further, the aqueous phase formula comprises 3-8% of glycerin, 2-6% of betaine, 2-6% of butanediol, 2-5% of 1, 2-pentanediol, 0.1-0.5% of potassium sorbate, 3.5-8.5% of carbomer gel and 28.897% -75.399% of deionized water;
the oil phase formula comprises 2-6% of vinyl polydimethylsiloxane crosslinked polymer, 1-6% of polydimethylsiloxane, 1-3% of polyglycerol-10 myristate, 1-3% of stearic acid, 1-3% of mono-diglyceride, 0.5-2% of tocopheryl acetate, 0.5-1% of squalane, 0.5-1% of phenoxyethanol, 0.1-0.8% of white pool seed oil and 0.2-0.8% of corn oil.
Further, the face cream comprises the following components in percentage by mass:
glycerol 6%, betaine 5%, carbomer gel 6.2%, carbomer 5%, dipeptide diamino Ding Xianbian-based amide diacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.4%, citric acid 0.001%, and the balance of ionized water; the carbomer gel is prepared by adding carbomer with the mass percentage of 5% into deionized water, and adjusting the pH to 8-9 by using 1.2% of triethanolamine.
Further, the method comprises the steps of,
the heating temperature of the water phase formula and the oil phase formula is 75-80 ℃;
the mixed emulsion is cooled to 45 ℃ for the first time;
the homogenizing and dispersing time is 5-10min;
the stirring speed is 30-50rpm.
The face cream prepared by the invention is mild and comfortable, harmonious and natural in fragrance, has the sun-proof effect while resisting aging, and is low in cost. Additional features and advantages of the invention will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. The objectives and other advantages of the invention will be realized and attained by the structure particularly pointed out in the written description and claims hereof.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more clear, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the data in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The invention provides sun-proof anti-aging face cream, which comprises the following components:
an aqueous phase formula, an oil phase formula, acetyl hexapeptide-8, a bird's nest extract, a cortex phellodendri extract and citric acid;
the aqueous phase formulation comprises dipeptide diamino Ding Xianbian-based amide diacetate, glycerol, betaine, butanediol, 1, 2-pentanediol, potassium sorbate, carbomer gel and deionized water;
the oil phase formulation includes vinyl dimethicone cross-linked polymer, dimethicone, polyglycerin-10 myristate, stearic acid, mono-di glyceride, tocopheryl acetate, squalane, phenoxyethanol, white pool seed oil, corn oil, methylenebis-benzotriazole tetramethylbutylphenol, and hexyl methoxycinnamate acetate.
Specifically, the face cream comprises the following components in percentage by mass:
66.397-89.499% of water phase formula, 8.1-28.1% of oil phase formula, 3.5-8.5% of carbomer gel, 80.5-2% of acetyl hexapeptide, 0.2-1% of bird's nest extract, 0.2-1% of cortex phellodendri extract and 0.001-0.003% of citric acid;
the aqueous phase formula comprises 2-5% of dipeptide diamino Ding Xianbian-based amide diacetate, 3-8% of glycerin, 2-6% of betaine, 2-6% of butanediol, 2-5% of 1, 2-pentanediol, 0.1-0.5% of potassium sorbate, 3.5-8.5% of carbomer gel and 28.897-75.399% of deionized water;
the oil phase formula comprises 0.2-1% of methylene bis-benzotriazole tetramethylbutylphenol, 0.1-0.5% of hexyl methoxycinnamate, 2-6% of vinyl polydimethylsiloxane cross-linked polymer, 1-6% of polydimethylsiloxane, 1-3% of polyglycerol-10 myristate, 1-3% of stearic acid, 1-3% of mono-diglyceride, 0.5-2% of tocopheryl acetate, 0.5-1% of squalane, 0.5-1% of phenoxyethanol, 0.1-0.8% of white pool seed oil and 0.2-0.8% of corn oil.
Wherein, the dipeptide diamino Ding Xianbian-base amide diacetate, the bird's nest extract and the acetyl hexapeptide-8 have the functions of removing wrinkles and resisting aging; the dipeptide diamino Ding Xianbian-base amide diacetate is a synthetic peptide simulating snake venom serum, can prevent the nerve conduction of acetylcholine and achieve the effect of relaxing muscles, thereby improving dynamic wrinkles, and has excellent smoothness and rapid wrinkle removal performance. The acetyl hexapeptide-8 can inhibit release of nerve conduction element acetylcholine, and reduce the amount of nerve conduction element acetylcholineThe contraction of weak muscles reduces dynamic lines and expression lines, reduces wrinkles, increases the activity of elastin, maintains the updating capacity of epidermis and makes skin smooth and compact. The nidus Collocaliae extract can be mixed with superoxide anion radical (O) 2- ) And hydroxyl radicals (-OH) to play a role in resisting free radical oxidation. In addition, the catalyst can be complexed with metal ions to reduce the generation of free radicals, and has a certain function of delaying aging. The methylene bis-benzotriazole tetramethyl butyl phenol is a broad-spectrum sun-screening agent, has the absorption wavelength of 280-400nm, has protective effects on ultraviolet A and ultraviolet B, and has good light stability and is not absorbed by skin as determined by researches until now. Hexyl methoxycinnamate is an oil-soluble UVB sunscreen agent, has absorption wavelength of 290-320nm, and has low skin irritation. And other substances are matched, so that a good anti-wrinkle and sun-screening effect is achieved, and the smoothness of the skin is improved.
The invention provides a sun-proof anti-aging face cream which is prepared by the following steps:
adding carbomer into deionized water, and regulating pH to about 8-9 with triethanolamine to prepare carbomer gel;
adding 3-8% of glycerol, 2-6% of betaine, 2-5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 2-6% of butanediol, 2-5% of 1, 2-pentanediol and 0.1-0.5% of potassium sorbate into the carbomer gel, homogenizing and dispersing for 5-10min, and heating to 75-80 ℃ for standby to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer, polydimethylsiloxane, polyglycerol-10 myristate, stearic acid, mono-diglyceride, tocopheryl acetate, squalane, phenoxyethanol, white pond flower seed oil, corn oil, methylene bis-benzotriazole tetramethylbutyl phenol and methoxy cinnamic acid hexyl acetate to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C, homogenizing for 5-10min to obtain mixed emulsion;
and cooling the mixed emulsion to 45 ℃ for the first time, adding acetyl hexapeptide-8, bird nest extract, cortex phellodendri extract and citric acid, homogenizing and dispersing uniformly, and cooling to room temperature for the second time to obtain the sun-proof anti-aging face cream.
Example 1
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 50.899%, glycerin 6%, betaine 5%, carbomer 5%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.3%, hexyl methoxycinnamate 0.3%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50.899% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.2% amine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, methylene bis-benzotriazole tetramethyl butylphenol 0.3% and methoxy cinnamic acid hexyl acetate 0.3% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 2
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 50.599%, glycerin 5%, betaine 4%, carbomer 5%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.3%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50.599% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.2% amine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, methylene bis-benzotriazole tetramethyl butylphenol 0.6% and methoxy cinnamic acid hexyl acetate 0.3% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 3
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 50.299%, glycerin 5%, betaine 4%, carbomer 5%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.9%, hexyl methoxycinnamate 0.3%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50.299% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.2% amine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, methylene bis-benzotriazole tetramethyl butylphenol 0.9% and methoxy cinnamic acid hexyl acetate 0.3% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 4
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 50.499%, glycerin 5%, betaine 4%, carbomer 5%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.4%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50.499% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.2% amine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, methylene bis-benzotriazole tetramethyl butylphenol 0.6% and methoxy cinnamic acid hexyl acetate 0.4% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 5
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 50.399%, glycerin 5%, betaine 4%, carbomer 5%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.5%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50.399% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.2% amine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, methylene bis-benzotriazole tetramethyl butylphenol 0.6% and methoxy cinnamic acid hexyl acetate 0.5% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 6
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 75.399%, glycerin 3%, betaine 2%, carbomer 3%, dipeptide diamino Ding Xianbian-ylamide diacetate 2%, butanediol 2%, 1, 2-pentanediol 2%, triethanolamine 0.5%, acetyl hexapeptide-80.5%, nidus Collocaliae extract 0.2%, potassium sorbate 0.1%, vinyl polydimethylsiloxane crosslinked polymer 2%, polydimethylsiloxane 2%, polyglycerin-10 myristate 1%, stearic acid 1%, mono-diglyceride 1%, tocopheryl acetate 0.5%, squalane 0.5%, phenoxyethanol 0.5%, white pool seed oil 0.1%, corn oil 0.2%, cortex Phellodendri bark extract 0.2%, methylenebis-benzotriazole tetramethylbutylphenol 0.2%, hexyl methoxycinnamate 0.1%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding carbomer 3% to deionized water 75.399%, and adjusting pH to about 8-9 with triethanolamine 0.5% amine to prepare carbomer gel;
adding 3% of glycerol, 2% of betaine, 3% of carbomer, 2% of dipeptide diamino Ding Xianbian-yl amide diacetate, 2% of butanediol, 2% of 1, 2-pentanediol and 0.1% of potassium sorbate into the carbomer gel, homogenizing and dispersing for 5-10min, and heating to 75-80 ℃ for standby to obtain a water phase formula;
mixing and heating vinyl polydimethylsiloxane cross-linked polymer 2%, polydimethylsiloxane 2%, polyglycerol-10 myristate 1%, stearic acid 1%, mono-diglyceride 1%, tocopheryl acetate 0.5%, squalane 0.5%, phenoxyethanol 0.5%, white pond flower seed oil 0.1%, corn oil 0.2%, methylene bis-benzotriazole tetramethyl butylphenol 0.2% and methoxy cinnamic acid hexyl acetate 0.1% to 75-80 ℃ for dissolution to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-80.5%, nidus Collocaliae extract 0.2%, cortex Phellodendri bark extract 0.2% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Example 7
The sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 28.897%, glycerin 8%, betaine 6%, carbomer 7%, dipeptide diamino Ding Xianbian% amidodiacetate 5%, butanediol 6%, 1, 2-pentanediol 5%, triethanolamine 1.5%, acetyl hexapeptide-82%, bird's nest extract 1%, potassium sorbate 0.5%, vinyl polydimethylsiloxane crosslinked polymer 6%, polydimethylsiloxane 6%, polyglycerin-10 myristate 3%, stearic acid 3%, mono-diglyceride 3%, tocopheryl acetate 2%, squalane 1%, phenoxyethanol 1%, white pool seed oil 0.8%, corn oil 0.8%, phellodendron bark extract 1%, methylenebis-benzotriazole tetramethylbutylphenol 1%, methoxycinnamic acid hexyl acetate 0.5%, citric acid 0.003%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 7% carbomer to 28.897% deionized water, and adjusting pH to about 8-9 with triethanolamine 1.5% amine to obtain carbomer gel;
adding 8% of glycerol, 6% of betaine, 7% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 6% of butanediol, 5% of 1, 2-pentanediol and 0.5% of potassium sorbate into the carbomer gel, homogenizing and dispersing for 5-10min, and heating to 75-80 ℃ for standby to obtain a water phase formula;
mixing vinyl polydimethylsiloxane crosslinked polymer 6%, polydimethylsiloxane 6%, polyglycerol-10 myristate 3%, stearic acid 3%, mono-diglyceride 3%, tocopheryl acetate 2%, squalane 1%, phenoxyethanol 1%, white pond flower seed oil 0.8%, corn oil 0.8%, methylene bis-benzotriazole tetramethyl butyl phenol 1% and methoxy cinnamic acid hexyl acetate 0.5%, heating to 75-80 ℃ and dissolving to obtain an oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-82%, nidus Collocaliae extract 1%, cortex Phellodendri bark extract 1% and citric acid 0.003%, homogenizing and dispersing uniformly, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Comparative examples:
the sun-proof anti-aging face cream comprises the following components in percentage by mass: deionized water 51.499%, glycerin 5%, betaine 4%, carbomer 5%, dipeptide diamino Ding Xianbian-yl amidodiacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-81%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-di-glyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pool seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, and citric acid 0.001%.
A preparation method of sun-proof anti-aging face cream is prepared by the following steps:
adding 5% carbomer to 50% deionized water, and adjusting pH to about 8-9 with 1.2% triethanolamine to obtain carbomer gel;
5% of glycerol, 4% of betaine, 5% of carbomer, 5% of dipeptide diamino Ding Xianbian-yl amide diacetate, 4% of butanediol, 4% of 1, 2-pentanediol and 0.4% of potassium sorbate are added into the carbomer gel, and the carbomer gel is uniformly dispersed for 5-10min and heated to 75-80 ℃ for standby, so as to obtain a water phase formula;
mixing vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pool seed oil 0.5% and corn oil 0.5%, and heating to 75-80deg.C for dissolving to obtain oil phase formula.
Adding the oil phase formula into the water phase formula, stirring uniformly at 75-80deg.C at 30-50rpm, homogenizing for 5-10min to obtain mixed emulsion;
cooling the mixed emulsion to 45deg.C for the first time, adding acetyl hexapeptide-81%, nidus Collocaliae extract 0.5%, cortex Phellodendri bark extract 0.5% and citric acid 0.001%, homogenizing, dispersing, cooling to room temperature for the second time, and obtaining sunscreen and antiaging cream.
Examples 1-7 and comparative examples described above are specifically shown in table 1 below, with the absorbance values in the corresponding uv spectrophotometer test cream samples shown in table 2 below.
Table 1 uv spectrophotometer to test absorbance values in cream samples
From Table 1, examples 1 and 2 show that the absorbance increases greatly at 200-400nm as the methylene bis-benzotriazole-based tetramethylbutylphenol content increases from 0.3% to 0.6%; as can be seen from examples 2 and 3, as the methylenebis-benzotriazole-based tetramethylbutylphenol content increases from 0.6% to 0.9%, the absorbance at 200 to 400nm slightly increases, but the increase is smaller, and it is preferable that the methylenebis-benzotriazole-based tetramethylbutylphenol content is 0.6% for the cost and effect.
As can be seen from examples 2 and 4, the absorbance at 200-400nm increases to some extent as the content of hexyl methoxycinnamate acetate increases from 0.3% to 0.4%; it can be seen from examples 4 and 5 that as the methylenebis-benzotriazole-based tetramethylbutylphenol content increases from 0.4% to 0.5%, the absorbance at 200 to 400nm increases less, and that the hexyl methoxycinnamate content is preferably 0.4% for cost and effect.
Human body skin spot pasting experiment
30 female test volunteers with healthy skin and no history of skin allergy were randomly selected, and were randomly divided into 2 groups of 15 persons each, and the sun-screening anti-wrinkle face creams of example 4 and comparative example were used. Selecting a proper spot tester, placing 0.002g of the sun-screening anti-wrinkle cream prepared in the example 4 and the comparative example in the spot tester respectively in a closed spot pasting test mode, pasting the sun-screening anti-wrinkle cream on the forearm of a subject by using an adhesive tape, testing for 24 hours, removing the tested object after the test is finished, observing skin reactions at 0.5, 24 and 48 hours respectively, and recording results according to skin reaction grading standards in cosmetic safety technical Specification.
From the experimental results, it can be seen that: no adverse reaction occurred in each group of subjects, indicating that the product was safe to use.
Wrinkle removal test
40 female test volunteers with healthy skin, 25-45 years old and no skin disease allergy history were randomly selected, and the cheek skin of the volunteers had symptoms such as fine lines or wrinkles. Volunteers were randomized into 2 groups of 20 persons each, using the sunscreen anti-wrinkle creams of example 4 and the control example. After the face of the subject was cleaned, test samples were taken and applied to both cheeks, once a day. The subjects were tested for changes in cheek wrinkle parameters, including skin roughness and number of wrinkles, using the skin wrinkle test (VISIOMETER SV 600), before use and after one month of trial, with each group being averaged, and the specific results being shown in Table 2.
TABLE 2 skin wrinkle removal test results
| Sample of | Variation of average roughness of skin/um | Percentage reduction in the number of wrinkles |
| Example 4 | 53.5 | 84 |
| Example 6 | 54.9 | 79 |
| Example 7 | 52.7 | 87 |
| Comparative examples | 54.1 | 82 |
From the test results in table 2, it can be seen that the cream has the effects of removing wrinkles and resisting aging while sun-screening, and the addition of sun-screening components has little influence on the anti-aging effect.
The invention uses the ultraviolet spectrophotometer to observe that the face cream sample has an absorption peak at the wavelength of 290-400 nm, which indicates that the face cream prepared by the invention has the effect of absorbing ultraviolet light; furthermore, the dipeptide diamino Ding Xianbian-base amide diacetate, the bird's nest extract and the acetyl hexapeptide-8 have the functions of removing wrinkles and resisting aging, and the cream has the characteristics of sun protection and resisting aging after the combination of the dipeptide diamino Ding Xianbian-base amide diacetate, the bird's nest extract and the acetyl hexapeptide-8.
Although the invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit and scope of the technical solutions of the embodiments of the present invention.
Claims (5)
1. A sun-proof anti-aging facial cream, which is characterized by comprising the following components in percentage by mass:
66.397-89.499% of water phase formula, 8.1-28.1% of oil phase formula, 0.5-2% of acetyl hexapeptide-8, 0.2-1% of bird's nest extract, 0.2-1% of cortex phellodendri bark extract and 0.001-0.003% of citric acid;
the aqueous phase formula comprises 2-5% of dipeptide diamino Ding Xianbian-based amide diacetate, 3-8% of glycerin, 2-6% of betaine, 2-6% of butanediol, 2-5% of 1, 2-pentanediol, 0.1-0.5% of potassium sorbate, 3.5-8.5% of carbomer gel and 28.897-75.399% of deionized water;
the oil phase formula comprises 0.2-1% of methylene bis-benzotriazole tetramethylbutylphenol, 0.1-0.5% of hexyl methoxycinnamate, 2-6% of vinyl polydimethylsiloxane cross-linked polymer, 1-6% of polydimethylsiloxane, 1-3% of polyglycerol-10 myristate, 1-3% of stearic acid, 1-3% of mono-diglyceride, 0.5-2% of tocopheryl acetate, 0.5-1% of squalane, 0.5-1% of phenoxyethanol, 0.1-0.8% of white pool seed oil and 0.2-0.8% of corn oil.
2. The sun-resistant and anti-aging facial cream according to claim 1, wherein the facial cream comprises the following components in percentage by mass:
glycerol 6%, betaine 5%, carbomer 5%, dipeptide diamino Ding Xianbian-diamide diacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-8 1%, bird's nest extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane cross-linked polymer 4.5%, polydimethylsiloxane 4%, polyglycerin-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pool flower seed oil 0.5%, corn oil 0.5%, phellodendron bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.4% and citric acid 0.001%, and the balance being ionized water;
the carbomer gel is prepared by adding carbomer with the mass percentage of 5% into deionized water, and adjusting the pH to 8-9 by using 1.2% of triethanolamine.
3. The preparation method of the sun-proof anti-aging face cream is characterized by comprising the following components in percentage by mass: 66.397-89.499% of water phase formula, 8.1-28.1% of oil phase formula, 80.5-2% of acetyl hexapeptide, 0.2-1% of bird's nest extract, 0.2-1% of cortex phellodendri extract and 0.001-0.003% of citric acid;
wherein the water phase formula comprises 2-5% of dipeptide diamino Ding Xianbian-based amide diacetate, 3-8% of glycerin, 2-6% of betaine, 2-6% of butanediol, 2-5% of 1, 2-pentanediol, 0.1-0.5% of potassium sorbate, 3.5-8.5% of carbomer gel and 28.897% -75.399% of deionized water;
the oil phase formula comprises 0.2-1% of methylene bis-benzotriazole tetramethylbutylphenol, 0.1-0.5% of methoxyl cinnamic acid hexyl acetate, 2-6% of vinyl polydimethylsiloxane crosslinked polymer, 1-6% of polydimethylsiloxane, 1-3% of polyglycerol-10 myristate, 1-3% of stearic acid, 1-3% of mono-diglyceride, 0.5-2% of tocopheryl acetate, 0.5-1% of squalane, 0.5-1% of phenoxyethanol, 0.1-0.8% of white pool seed oil and 0.2-0.8% of corn oil;
the preparation method comprises the following steps:
adding carbomer into deionized water, and regulating the pH to 8-9 by using triethanolamine to prepare carbomer gel;
adding the aqueous phase formula into the carbomer gel, homogenizing and dispersing, and heating for later use; the aqueous formulation includes a dipeptide diamino Ding Xianbian-based amide diacetate;
mixing the oil phase formula, heating and dissolving; the oil phase formulation comprises methylene bis-benzotriazole tetramethylbutylphenol and hexyl methoxycinnamate acetate;
adding the oil phase formula into the water phase formula, stirring uniformly under heating, and homogenizing and dispersing to obtain a mixed emulsion;
and (3) cooling the mixed emulsion for the first time, adding acetyl hexapeptide-8, bird nest extract, cortex phellodendri extract and citric acid, homogenizing and dispersing uniformly, and cooling to room temperature for the second time to obtain the sun-proof anti-aging face cream.
4. A process for preparing a sunscreen anti-aging cream according to claim 3,
the face cream comprises the following components in percentage by mass:
glycerol 6%, betaine 5%, carbomer gel 6.2%, carbomer 5%, dipeptide diamino Ding Xianbian-based amide diacetate 5%, butanediol 4%, 1, 2-pentanediol 4%, triethanolamine 1.2%, acetyl hexapeptide-8 1%, nidus Collocaliae extract 0.5%, potassium sorbate 0.4%, vinyl polydimethylsiloxane crosslinked polymer 4.5%, polydimethylsiloxane 4%, polyglycerol-10 myristate 2%, stearic acid 2%, mono-diglyceride 2%, tocopheryl acetate 1%, squalane 0.8%, phenoxyethanol 0.6%, white pond flower seed oil 0.5%, corn oil 0.5%, cortex Phellodendri bark extract 0.5%, methylenebis-benzotriazole tetramethylbutylphenol 0.6%, hexyl methoxycinnamate 0.4%, and citric acid 0.001%, with the balance being ionized water; the carbomer gel is prepared by adding carbomer with the mass percentage of 5% into deionized water, and adjusting the pH to 8-9 by using 1.2% of triethanolamine.
5. A process for preparing a sunscreen anti-aging cream according to claim 3 or 4,
the heating temperature of the water phase formula and the oil phase formula is 75-80 ℃;
the mixed emulsion is cooled to 45 ℃ for the first time;
the homogenizing and dispersing time is 5-10min;
the stirring speed is 30-50rpm.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109662940A (en) * | 2018-02-26 | 2019-04-23 | 广州高缇雅精细化工有限公司 | A kind of full photoprotection raw material |
| CN110327228A (en) * | 2019-07-09 | 2019-10-15 | 广州艾蓓生物科技有限公司 | A kind of suncream |
| CN111481460A (en) * | 2020-04-14 | 2020-08-04 | 广州市暨新颜生物科技有限公司 | Polypeptide anti-wrinkle anti-aging essence and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109662940A (en) * | 2018-02-26 | 2019-04-23 | 广州高缇雅精细化工有限公司 | A kind of full photoprotection raw material |
| CN110327228A (en) * | 2019-07-09 | 2019-10-15 | 广州艾蓓生物科技有限公司 | A kind of suncream |
| CN111481460A (en) * | 2020-04-14 | 2020-08-04 | 广州市暨新颜生物科技有限公司 | Polypeptide anti-wrinkle anti-aging essence and preparation method thereof |
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