CN114008039B - 作为人ctps1抑制剂用于治疗增殖性疾病的化合物 - Google Patents

作为人ctps1抑制剂用于治疗增殖性疾病的化合物 Download PDF

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CN114008039B
CN114008039B CN202080041337.0A CN202080041337A CN114008039B CN 114008039 B CN114008039 B CN 114008039B CN 202080041337 A CN202080041337 A CN 202080041337A CN 114008039 B CN114008039 B CN 114008039B
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cell
compound
compounds
lymphoma
formula
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CN114008039A (zh
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A·库杜斯
A·诺瓦克
D·卡森
E·布莱克姆
G·琼斯
J·维格勒沃斯
L·达菲
L·比尔克
P·乔治
S·阿赫麦德
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Stapp Pharmaceutical Co ltd
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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CN202080041337.0A 2019-06-04 2020-06-04 作为人ctps1抑制剂用于治疗增殖性疾病的化合物 Active CN114008039B (zh)

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Application Number Priority Date Filing Date Title
EP19305713 2019-06-04
EP19305713.0 2019-06-04
EP19306144.7 2019-09-20
EP19306144 2019-09-20
PCT/IB2020/000559 WO2020245664A1 (en) 2019-06-04 2020-06-04 N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl) tetrahydro-2h-pyran-4-carboxamide derivatives and related compounds as human ctps1 inhibitors for the treatment of proliferative diseases

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CN114008039B true CN114008039B (zh) 2024-01-16

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JP (1) JP7595593B2 (cg-RX-API-DMAC7.html)
CN (1) CN114008039B (cg-RX-API-DMAC7.html)
DK (1) DK3980411T3 (cg-RX-API-DMAC7.html)
ES (1) ES3044436T3 (cg-RX-API-DMAC7.html)
FI (1) FI3980411T3 (cg-RX-API-DMAC7.html)
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