CN113797303A - A Chinese medicinal composition for treating diabetes, and its preparation method - Google Patents
A Chinese medicinal composition for treating diabetes, and its preparation method Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating diabetes, which specifically comprises the following raw materials in parts by weight: 45-55 parts of prepared rhizome of rehmannia, 25-35 parts of medlar, 25-35 parts of salt fructus psoraleae, 25-35 parts of red ginseng, 10-20 parts of radix asparagi, 10-20 parts of radix ophiopogonis, 10-20 parts of ginger, 10-20 parts of Chinese date and 45-55 parts of black peach. The invention also discloses a preparation method of the traditional Chinese medicine composition, which comprises the following steps: weighing raw materials for later use; parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, grinding into powder, decocting the rest materials with water to obtain medicinal liquid, making into unguent, mixing with the medicinal powder, adding vaseline, stirring, and making into pill. The traditional Chinese medicine composition provided by the invention has the advantages of high curative effect, no toxic or side effect after long-term use, reliable curative effect and convenience in taking.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating diabetes and a preparation method thereof.
Background
With the improvement of living standard and the change of dietary structure of people, the population of hyperglycemia and hypertension is increasing, the number of diabetic patients is also increasing, and the hyperglycemia existing in the long term of diabetes causes chronic damage and dysfunction of various tissues, especially eyes, kidneys, hearts, blood vessels and nerves.
Diabetes is classified into type I diabetes, type II diabetes, and specific type diabetes. The diabetes mellitus type II is also called diabetes mellitus, is an acquired disease, is abundant in life, reduces activity, continuously increases the number of patients with the diabetes mellitus type II, at present, 13% of people in China suffer from the diabetes mellitus type II, which is well developed in adults, serious people are accompanied by various complications, such as macrovascular complications, microvascular complications and nerve complications, and the diabetes mellitus type II is manifested as diabetes mellitus combined with cerebral infarction, diabetes mellitus combined with coronary heart disease, diabetes mellitus combined with hypertension, diabetic lower limb angiopathy, diabetic foot, diabetic retinopathy, diabetic cataract, diabetic skin lesion and diabetic peripheral neuropathy, wherein the diabetes mellitus belongs to common microvascular complications of nephropathy, a large amount of proteinuria can be caused, the serious people even have end-stage nephropathy, and the complications have great harm to the body and life of the people, so that many people are disabled or dead.
At present, the medicines for clinically treating the type II are mainly oral hypoglycemic medicines except insulin, and are roughly divided into sulfonylureas, biguanides, traditional Chinese medicine preparations, other hypoglycemic medicines and auxiliary medicines. However, the side effects of these oral medicines are mainly manifested in that they have certain damage to blood phase and liver function, which can cause diabetic cardiovascular and cerebrovascular complications of patients, easily cause hypoglycemia reaction, have irritation to stomach and intestine, and cause anorexia, nausea, vomiting and even diarrhea.
Therefore, the technical problem to be solved by the technical personnel in the field needs to be solved by providing a Chinese medicinal composition for treating diabetes, which has high efficiency, no toxic or side effect after long-term use, reliable curative effect and convenient administration, and a preparation method thereof,
disclosure of Invention
The invention overcomes the defects of the prior art and provides a traditional Chinese medicine composition for treating diabetes and a preparation method thereof. The composition takes a pure Chinese medicinal preparation as a formula, and can effectively treat diabetes without generating side effects on a body.
In order to achieve the purpose, the invention adopts the following technical scheme:
a traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight: 45-55 parts of prepared rhizome of rehmannia, 25-35 parts of medlar, 25-35 parts of salt fructus psoraleae, 25-35 parts of red ginseng, 10-20 parts of radix asparagi, 10-20 parts of radix ophiopogonis, 10-20 parts of ginger, 10-20 parts of Chinese date and 45-55 parts of black peach.
Preferably, the traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
47-53 parts of prepared rhizome of rehmannia, 27-33 parts of medlar, 27-33 parts of salt fructus psoraleae, 27-33 parts of red ginseng, 12-18 parts of radix asparagi, 12-18 parts of radix ophiopogonis, 12-18 parts of ginger, 12-18 parts of Chinese date and 47-53 parts of black peach.
Preferably, the traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
50 parts of prepared rhizome of rehmannia, 30 parts of medlar, 30 parts of salt fructus psoraleae, 30 parts of red ginseng, 15 parts of asparagus, 15 parts of dwarf lilyturf tuber, 15 parts of ginger, 15 parts of Chinese date and 50 parts of black peach.
A preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) weighing the raw materials for later use;
(2) parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, and grinding into powder;
(3) putting fructus Lycii, Ginseng radix Rubri, rhizoma Zingiberis recens, fructus Jujubae, and fructus Persicae into a container, adding five times of water, boiling, cooling, soaking for 9-11 hr, and collecting the extractive solution; adding water in three times amount into the residue, boiling, cooling, soaking for 5-6 hr, and collecting the soaking solution; mixing the two extractive solutions, heating and evaporating to obtain unguent;
(4) and (3) mixing the powder obtained in the step (2) with the ointment prepared in the step (3), adding vaseline, uniformly stirring, and preparing pills of 6-8 g.
Preferably, the particle size of the powder in the step (2) is 100-110 meshes;
preferably, the temperature of heating and evaporating in the step (3) is 65-70 ℃, and the relative density of the prepared ointment is 1.16-1.18.
The properties and the curative effect of each component of the invention are as follows:
prepared rhizome of rehmannia: sweet and warm, entering liver and kidney meridians. The functions are mainly to nourish yin and enrich blood. It is indicated for deficiency of yin and blood, atrophy and weakness of waist and knees, fatigue, cough, steaming bone, seminal emission, metrorrhagia, menoxenia, diabetes, scanty urine, deafness and blurred vision.
Medlar: sweet and neutral. Has effects in nourishing liver, replenishing kidney essence, and moistening lung
Salt fructus psoraleae: bitter, pungent and warm. It enters kidney and spleen meridians. Has effects in invigorating kidney, supporting yang, arresting spontaneous emission, arresting polyuria, treating lumbago due to kidney deficiency, frequent micturition, infantile enuresis, renal leak, warming spleen, relieving diarrhea, and relieving asthma.
Red ginseng: has effects of invigorating primordial qi, restoring pulse, relieving depletion, invigorating qi, and regulating blood, and can be used for treating asthenia, collapse, cold limbs, slight pulse, qi failing to control blood, metrorrhagia, metrostaxis, etc.
Asparagus: sweet, bitter and cold in nature, entering lung and kidney meridians, has the effects of nourishing yin, moistening dryness, clearing lung-heat and promoting fluid production. It is commonly indicated for dry cough due to lung dryness, cough with sticky phlegm, soreness and pain of waist and knees, bone-steaming tidal fever, internal heat, thirst, fever, fluid damage, dry throat, thirst, constipation due to intestinal dryness.
Radix ophiopogonis: sweet and slightly bitter taste, slightly cold nature, entering stomach, lung and heart channels, has effects of nourishing yin and moistening lung, benefiting stomach and promoting fluid production, clearing heart fire and relieving restlessness, and can be used for treating dry cough due to lung dryness, tuberculosis cough due to yin deficiency, pharyngitis, pharyngalgia, body fluid injury, thirst, internal heat, diabetes, vexation, insomnia, constipation due to intestinal dryness, etc.
Ginger: pungent in flavor and slightly warm in nature. It enters lung, spleen and stomach meridians. Has effects of relieving exterior syndrome, dispelling cold, warming spleen and stomach, relieving vomit, warming lung, relieving cough, and removing toxic substance, and can be used for treating wind-cold type common cold, spleen and stomach cold syndrome, stomach cold type emesis, lung cold type cough, and fish and crab toxin.
Chinese date: sweet and warm, entering spleen and stomach meridians. Has the effects of invigorating spleen, regulating stomach function, invigorating qi, promoting fluid production, regulating ying and wei, and removing toxic substances. It is indicated for deficiency of stomach and food, spleen weakness, loose stool, qi, blood and body fluids deficiency, disharmony between ying and wei, palpitation. The dirty feeling of women, etc.
Through the technical scheme, compared with the prior art, the invention has the following beneficial effects:
1. according to the invention, by applying the medical theory and according to the constitutional features of the diabetics, the raw materials of the rehmannia glutinosa, the medlar, the fructus psoraleae, the red ginseng, the asparagus fern, the radix ophiopogonis, the ginger, the Chinese date and the like are matched in a targeted way, the advantages of the components are complementary after being matched, no toxic or side effect is caused, and the curative effect is reliable.
2. The composition contains the red ginseng and the unique argininyl-fructosy glucose in the red ginseng, has the effects of resisting diabetes, resisting obesity, enhancing the immune function, eliminating free radicals, promoting microcirculation and protecting skin.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
55 parts of prepared rhizome of rehmannia, 35 parts of medlar, 35 parts of salt fructus psoraleae, 35 parts of red ginseng, 20 parts of radix asparagi, 20 parts of radix ophiopogonis, 20 parts of ginger, 20 parts of Chinese date and 55 parts of black peach.
Example 2
A traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
45 parts of prepared rhizome of rehmannia, 25 parts of medlar, 255 parts of salt fructus psoraleae, 25 parts of red ginseng, 10 parts of asparagus, 10 parts of dwarf lilyturf tuber, 10 parts of ginger, 10 parts of Chinese date and 45 parts of black peach.
Example 3
A traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
53 parts of prepared rhizome of rehmannia, 33 parts of medlar, 33 parts of fructus psoraleae, 33 parts of red ginseng, 18 parts of radix asparagi, 18 parts of radix ophiopogonis, 18 parts of ginger, 18 parts of Chinese date and 53 parts of black peach.
Example 4
A traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
47 parts of prepared rhizome of rehmannia, 27 parts of medlar, 27 parts of fructus psoraleae, 27 parts of red ginseng, 12 parts of radix asparagi, 12 parts of radix ophiopogonis, 12 parts of ginger, 12 parts of Chinese date and 47 parts of black peach.
Example 5
A traditional Chinese medicine composition for treating diabetes comprises the following raw materials in parts by weight:
50 parts of prepared rhizome of rehmannia, 30 parts of medlar, 30 parts of salt fructus psoraleae, 30 parts of red ginseng, 15 parts of asparagus, 15 parts of dwarf lilyturf tuber, 15 parts of ginger, 15 parts of Chinese date and 50 parts of black peach.
Example 6
A preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) weighing the raw materials as described in any one of examples 1-5 for later use;
(2) parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, grinding into powder, and sieving with 110 mesh sieve;
(3) putting fructus Lycii, Ginseng radix Rubri, rhizoma Zingiberis recens, fructus Jujubae, and fructus Persicae into a container, adding five times of water, boiling, cooling, soaking for 11 hr, and collecting the extractive solution; adding water in three times amount into the residue, boiling, cooling, soaking for 6 hr, and collecting the soaking solution; mixing the two soaking solutions, and heating and evaporating at 70 deg.C to obtain unguent with relative density of 1.18;
(4) mixing the powder obtained in step (2) with the ointment obtained in step (3), adding vaseline, stirring, and making into pill of 8g per pill
Example 7
A preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) weighing the raw materials as described in any one of examples 1-5 for later use;
(2) parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, grinding into powder, and sieving with 100 mesh sieve;
(3) putting fructus Lycii, Ginseng radix Rubri, rhizoma Zingiberis recens, fructus Jujubae, and fructus Persicae into a container, adding five times of water, boiling, cooling, soaking for 9 hr, and collecting the extractive solution; adding water in three times amount into the residue, boiling, cooling, soaking for 5 hr, and collecting the soaking solution; mixing the two extractive solutions, and heating at 65 deg.C for evaporation to obtain unguent with relative density of 1.16;
(4) and (3) mixing the powder obtained in the step (2) with the ointment prepared in the step (3), adding vaseline, and uniformly stirring to prepare pills of 6g per pill.
Example 8
A preparation method of a traditional Chinese medicine composition for treating diabetes comprises the following steps:
(1) weighing the raw materials as described in any one of examples 1-5 for later use;
(2) parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, grinding into powder, and sieving with 110 mesh sieve;
(3) putting fructus Lycii, Ginseng radix Rubri, rhizoma Zingiberis recens, fructus Jujubae, and fructus Persicae into a container, adding five times of water, boiling, cooling, soaking for 10 hr, and collecting the extractive solution; adding water in three times amount into the residue, boiling, cooling, soaking for 5.5 hr, and collecting the soaking solution; mixing the two soaking solutions, and heating at 67 deg.C for evaporation to obtain unguent with relative density of 1.17;
(4) and (3) mixing the powder obtained in the step (2) with the ointment prepared in the step (3), adding vaseline, and uniformly stirring to prepare pills of 7g per pill.
And (3) testing clinical effects:
300 diabetic patients, aged 30-65 years, without severe systemic diseases, immunodeficiency or autoimmune diseases, and without serious allergic history to drugs, were randomly assigned into six groups, and the following table shows statistics of the therapeutic effect after continuous use for 5 months, 2 times per day, using the Chinese medicinal composition of examples 1-5, and the results are shown in table 1:
the judgment standard of the curative effect condition is as follows:
significant effect-blood sugar is obviously reduced or recovered to normal level, and complication symptoms are obviously relieved;
effective-some blood sugar is reduced and the complication symptom is relieved;
ineffectiveness-no significant or upward decline in blood glucose, no improvement or a tendency toward exacerbation of the complications.
TABLE 1
Group of | n | Show effect | Is effective | Invalidation | Total effective rate |
Example 1 | 60 | 41 | 14 | 5 | 92% |
Example 2 | 60 | 48 | 8 | 4 | 94% |
Example 3 | 60 | 44 | 11 | 5 | 92% |
Example 4 | 60 | 47 | 5 | 6 | 90% |
Example 5 | 60 | 41 | 16 | 3 | 95% |
As can be seen from the above table, the effective rates of the traditional Chinese medicine compositions prepared in the embodiments are all above 90% in the aspects of reducing blood sugar and relieving diabetic complications, i.e., the traditional Chinese medicine composition of the present application has a good effect in improving diabetes and diabetic complications.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (6)
1. The traditional Chinese medicine composition for treating diabetes is characterized by comprising the following raw materials in parts by weight: 45-55 parts of prepared rhizome of rehmannia, 25-35 parts of medlar, 25-35 parts of salt fructus psoraleae, 25-35 parts of red ginseng, 10-20 parts of radix asparagi, 10-20 parts of radix ophiopogonis, 10-20 parts of ginger, 10-20 parts of Chinese date and 45-55 parts of black peach.
2. The traditional Chinese medicine composition for treating diabetes according to claim 1, which is characterized by comprising the following raw materials in parts by weight:
47-53 parts of prepared rhizome of rehmannia, 27-33 parts of medlar, 27-33 parts of salt fructus psoraleae, 27-33 parts of red ginseng, 12-18 parts of radix asparagi, 12-18 parts of radix ophiopogonis, 12-18 parts of ginger, 12-18 parts of Chinese date and 47-53 parts of black peach.
3. The traditional Chinese medicine composition for treating diabetes according to claim 2, which is characterized by comprising the following raw materials in parts by weight:
50 parts of prepared rhizome of rehmannia, 30 parts of medlar, 30 parts of salt fructus psoraleae, 30 parts of red ginseng, 15 parts of asparagus, 15 parts of dwarf lilyturf tuber, 15 parts of ginger, 15 parts of Chinese date and 50 parts of black peach.
4. A preparation method of a traditional Chinese medicine composition for treating diabetes is characterized by comprising the following steps:
(1) weighing the raw materials as described in any one of claims 1 to 3 for later use;
(2) parching radix rehmanniae Preparata, fructus Psoraleae, radix asparagi, and radix Ophiopogonis with slow fire, cooling, pulverizing, and grinding into powder;
(3) putting fructus Lycii, Ginseng radix Rubri, rhizoma Zingiberis recens, fructus Jujubae, and fructus Persicae into a container, adding five times of water, boiling, cooling, soaking for 9-11 hr, and collecting the extractive solution; adding water in three times amount into the residue, boiling, cooling, soaking for 5-6 hr, and collecting the soaking solution; mixing the two extractive solutions, heating and evaporating to obtain unguent;
(4) and (3) mixing the powder obtained in the step (2) with the ointment prepared in the step (3), adding vaseline, uniformly stirring, and preparing pills of 6-8 g.
5. The method as claimed in claim 4, wherein the particle size of the powder in step (2) is 100-110 mesh.
6. The preparation method of the Chinese medicinal composition for treating diabetes according to claim 4, wherein the temperature of heating and evaporation in the step (3) is 65-70 ℃, and the relative density of the prepared ointment is 1.16-1.18.
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CN101862413A (en) * | 2010-07-09 | 2010-10-20 | 喇孝瑾 | Chinese medicinal preparation for treating type-2 diabetes and preparation method thereof |
CN102949598A (en) * | 2012-12-04 | 2013-03-06 | 曹法政 | Pill for alleviating diabetic symptoms and preparation method thereof |
CN110732015A (en) * | 2019-11-29 | 2020-01-31 | 江苏师范大学 | A Chinese medicinal composition for treating diabetes due to deficiency of both qi and yin |
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2020
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101862413A (en) * | 2010-07-09 | 2010-10-20 | 喇孝瑾 | Chinese medicinal preparation for treating type-2 diabetes and preparation method thereof |
CN102949598A (en) * | 2012-12-04 | 2013-03-06 | 曹法政 | Pill for alleviating diabetic symptoms and preparation method thereof |
CN110732015A (en) * | 2019-11-29 | 2020-01-31 | 江苏师范大学 | A Chinese medicinal composition for treating diabetes due to deficiency of both qi and yin |
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