CN109260403A - A kind of Chinese medicine composition for treating cancer of pancreas - Google Patents

Abstract

The invention discloses a kind of Chinese medicine compositions for treating cancer of pancreas, belong to the field of Chinese medicines.Effective component of pharmaceutical composition is Radix Codonopsis, rhizoma atractylodis macrocephalae, Poria cocos, fushen, coloured malt, fries rice sprout, RHIIZOMA DIOSCOREAE from Henan of China, the dried immature fruit of citron orange, full Snakegourd Fruit, caulis perllae, dried orange peel, umbellate pore furgus, pinellia, semen coicis, paniculate swallowwort, fiveleaf akebia fruit and radix glycyrrhizae preparata in this.The Chinese medicine composition can be used for treating cancer of pancreas, the beneficial effect which acts on human body be single dose it is incomparable.The simple production process of the drug is easy to take, is significant in efficacy, is a kind of Chinese medicine composition of ideal treatment cancer of pancreas.

Description

A kind of Chinese medicine composition for treating cancer of pancreas

Technical field

The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating cancer of pancreas.

Background technique

Cancer of pancreas (Pancreatic cancer) is a kind of common alimentary system malignant tumour, and grade malignancy is high, Diagnosing and treating is all highly difficult, accounts for about the 1%-4% of whole body malignant tumour.The hair age, wherein male was common at 50-70 years old well.5 Annual survival rate is only 3%-5%, is worst one of the malignant tumour of prognosis.The concealment of cancer of pancreas early symptom, lacks specificity Performance, therefore early diagnostic rate is extremely low, occurs having belonged to advanced stage mostly when symptom.Once making a definite diagnosis, cancer of pancreas has usually been shifted, The complex treatments such as Radiotherapy chemotherapy are little to the survival benefit for improving patient, this keeps the death rate of Pancreas cancer patients high, more than 90% Patient it is dead in 1 year after making a definite diagnosis.The World Health Organization's global cancer research report display in 2014, cancer of pancreas have become The seventh-largest lethal cancer in the whole world, 5 years survival rates are less than 5%, and in the U.S., such cancer is the fourth-largest lethal cancer.Though The development of right medicine makes many cancers there has been preferable therapeutic effect, but regrettably, exactly people not yet attack cancer of pancreas Gram one of cancer, it is all undesirable from prevention, diagnosis, treatment to outcome, with China's improvement of living standard and diet The change of structure, the disease incidence of cancer of pancreas is presented ascendant trend and has rejuvenation tendency in recent years.

Operation, radiotherapy, chemotherapy are three big means of current treating cancer, but they all respectively have limitation: operation is early to processing The tumour of phase is effective, it is more small to lesion or have occurred and that transfer without effect；Radiation and chemotherapy toxic side effect is big, to disease The immune of people, hemopoietic system will cause serious damage.

Cancer of pancreas grade malignancy is high, and poor prognosis, life cycle is short, and treatment is difficult, these all promote traditional Chinese medicine treatment pancreas The clinical research of cancer, and facts proved that, traditional Chinese medicine treatment cancer of pancreas tool has a better effect, and document report has affirmed fully Chinese medicine The clinical efficacy of medicine treatment cancer of pancreas.

Cancer of pancreas there is no definite description in traditional Chinese medicine document, and according to its Clinical presentation and feature, cancer of pancreas is cured in motherland The ranges such as " mass located in the upper or lower abdomen ", " Disorder lumps in the abdomen that belong in ", " accumulation ", " abdominal pain ", " jaundice " more.Such as from the point of view of the clinical manifestation of cancer of pancreas, Abdominal pain, abdomen turgor are uncomfortable, abdomen block is then classified as " disease ", " product ", and abdominal pain, mesh Huang, whole skin xanthochromia, pruitus are then classified as " jaundice " etc..

Motherland's medicine is substantially divided into three phases to the understanding of cancer of pancreas.Many discussions of initial stage have been related to pancreas The performance when diseased region of cancer and morbidity.For example, " difficult through 56 hardly possiblies " piece: mass located in the upper or lower abdomen " rises on navel, as large as arm, up to the heart Under ".Mass at the right hypochondrium " in gastral cavilty, cover as large as disk, be not cured long, make us flaccidity of limbs, subcutaneous ulcer of turning to be yellow, diet is not skin " etc.；Treatise on Febrile Diseases In " accumulation of pathogens in chest ", " diaphragmodynia ", " pained " etc disease, all may include the lesion of cancer of pancreas.When second stage is Song, gold, member Phase, it is understood that the prognosis difficult to treat of this disease is bad.For example, " General Records of Holy Universal Relief " is recorded, " pneumatosis is not recovered long in abdomen, securely pushes away it It does not move, there is disease.It is tied by its its strong such as cup disk jail, long endlessly, makes us thin and abdomen is big, until stubbornly refusing to control." three phases are clear Generation, Chinese medicine anatomy have new development, and the concept of pancreas is also clear earlier above, and " mass located in the upper or lower abdomen ", " disease product " is long-pending to summarize pancreas, recognize It is interrelated for this disease and the physiological and pathological of liver, spleen.Spleen deficiency liver depression, functional activity of QI being not smooth, transporting mistake department, retention of water-damp, strongly fragrant longization heat, Damp-heat accumulation, with the passing of time at poison, damp heat in the spleen and the stomach suffocating of liver and gall and the whole body appearance is all yellow；Feelings will is disgruntled, and stagnation of liver qi or diet are not Section or overfeeding savoury, and the spleen weakness that arrives, qi depression to blood stasis, mass located in the upper or lower abdomen accumulation of pathogens in chest diaphragmodynia form liver and spleen stasis.This is examined for later age Chinese medicine It controls cancer of pancreas and provides a theory of traditional Chinese medical science basis.

Also there is a lot of discussion in each family in the present age for the etiology and pathogenesis understanding of cancer of pancreas.Wang Qing ability etc. thinks that cancer of pancreas belongs to Chinese medicine " mass located in the upper or lower abdomen " scope, etiology and pathogenesis mostly due to seven feelings pent-ups or feeding desorder, long and liver and spleen is impaired, internal organs are become estranged, spleen fortune It is obstructed, retention of damp-heat in the interior, in ecchymosis caused by knot.Yang Ping Kui, Sun Yubing all think that the sick position of this disease is liver and gallbladder, pathogenesis in pancreas in fact For exogenous disease Shi Re Bing Pian, liver and gallbladder mechanism of qi is obstructed, and catharsis is not normal, and the excessive disorder of qi of bile, channels is obstructed, and Shi Re Bing Pian is mutual with the stasis of blood Knot, stay for a long time and do not go, product card at.Zhou Zhongying thinks that cancer of pancreas is mostly that liver and spleen two is hurt, and soil loses scouring rush, QI failing to transform into body fluid, hot and humid ecchymosis Mutually knot causes.Wu Yingmei then thinks that dysfunction of spleen and stomach, body's immunity are lowly the key point of cancer of pancreas morbidity, morbidity Mechanism has inside and outside two because of, the damp and hot heresy of exogenous disease, from outward appearance to inner essence strongly fragrant and change heat or interior delicious food of being addicted to drink, spleen deficiency dysfunction of the spleen in transportation and transformation, it is wet it is turbid in Raw, inside and outside damp and hot heresy is harmonious, knot with the passing of time in heat toxin, qi depression to blood stasis, then at disease product lump.

To sum up, ancient Chinese medicine doctor is thought: cancer of pancreas be mostly exogenous disease wet poison, disorder of emotion, eating and drinking without temperance or cigarette poisonous wine it is wet etc. because Element for suffer from, cause stagnation of liver-QI with deficiency of the spleen, it is damp and hot accumulate steaming, ecchymosis internal resistance forms.

You Jianliang professor, centering medical treatment cancer of pancreas have made intensive studies, and have collected a large amount of clinical data, accumulate Clinical experience abundant, proposes the novel viewpoint of oneself.

Professor You Jianliang thinks: the gene that the occurrence and development of cancer of pancreas and the dystrophy day after tomorrow, feeding desorder, seven feelings pent-ups induce Mutation, body's immunity are out of control closely related.Suffer from the deficiency of vital energy after cancer and strongly fragrant, bile excretion is obstructed, so that there is yang blood and qi Inverse random complex situations, but middle burnt dysfunction of spleen and stomach is its key, spleen deficiency is then wooden strongly fragrant, soil void then give birth to it is wet, qi depression to blood stasis with it is wet Mutually knot blocks biliary tract into disease product, and bile is excessive to form jaundice.Mass located in the upper or lower abdomen contamination, then gas consumption is hurt just long, the more impairment of the spleen.

Summary of the invention

The purpose of the present invention is overcoming the deficiencies in the prior art, a kind of Chinese traditional medicine composition for treating cancer of pancreas is provided Object, simple and easy to do, curative effect affirmative.

The purpose of the present invention can be achieved through the following technical solutions:

A kind of Chinese medicine composition for treating cancer of pancreas, the effective component and dosage of each component of the Chinese medicine composition are as follows: party Ginseng 1~80 part, 1~60 part of rhizoma atractylodis macrocephalae, 1~50 part of Poria cocos, 1~50 part of fushen, 1~80 part of coloured malt, fry 1~80 part of rice sprout, 1~60 part of RHIIZOMA DIOSCOREAE from Henan of China, 1~50 part of the dried immature fruit of citron orange, 1~50 part of full Snakegourd Fruit, 1~50 part of caulis perllae, 1~30 part of dried orange peel, 1~90 part of umbellate pore furgus, 1~50 part of pinellia, 1~60 part of semen coicis, 1~90 part of paniculate swallowwort, 1~90 part of fiveleaf akebia fruit and 1~30 part of radix glycyrrhizae preparata.

In some preferred technical solutions, the dosage of each component of the Chinese medicine composition of the treatment cancer of pancreas is as follows: 1~30 part of Radix Codonopsis, 1~30 part of rhizoma atractylodis macrocephalae, 10~40 parts of Poria cocos, 10~40 parts of fushen, 10~60 parts of coloured malt, fry rice sprout 10~ 60 parts, 10~45 parts of RHIIZOMA DIOSCOREAE from Henan of China, 10~30 parts of the dried immature fruit of citron orange, 10~30 parts of full Snakegourd Fruit, 10~30 parts of caulis perllae, 6~18 parts of dried orange peel, umbellate pore furgus 30~90 parts, 12~36 parts of pinellia, 20~60 parts of semen coicis, 30~90 parts of paniculate swallowwort, 30~90 parts of fiveleaf akebia fruit and radix glycyrrhizae preparata 6 ~18 parts.

In some more preferably technical solutions, the dosage of each component of the Chinese medicine composition of the treatment cancer of pancreas is such as Under: 10~30 parts of Radix Codonopsis, 12~36 parts of Poria cocos, 12~36 parts of fushen, 20~60 parts of coloured malt, fries paddy at 10~30 parts of rhizoma atractylodis macrocephalae 20~60 parts of bud, 15~45 parts of RHIIZOMA DIOSCOREAE from Henan of China, 10~30 parts of the dried immature fruit of citron orange, 10~30 parts of full Snakegourd Fruit, 10~30 parts of caulis perllae, dried orange peel 6~18 Part, 30~90 parts of umbellate pore furgus, 12~36 parts of pinellia, 20~60 parts of semen coicis, 30~90 parts of paniculate swallowwort, 30~90 parts of fiveleaf akebia fruit and 6~18 parts of radix glycyrrhizae preparata.

In technical solution of the present invention: the full Snakegourd Fruit is made of PERICARPIUM TRICHOSANTHIS and Snakegourd Seed, and PERICARPIUM TRICHOSANTHIS and Snakegourd Seed Mass ratio is 5~15:5~15.

After the effective component mixing of the Chinese medicine composition for the treatment of cancer of pancreas described in technical solution of the present invention, pharmacy is added Clinically-acceptable dosage form is made in acceptable auxiliary material；The dosage form is the preparation of peroral dosage form.

Chinese medicine composition described in technical solution of the present invention is as the purposes in preparation prevention and treatment pancreatic cancer drug.

Fang Zhong:

Radix Codonopsis: tonifying middle-Jiao and Qi, stomach function regulating are promoted the production of body fluid, expelling phlegm and arresting coughing.

Rhizoma atractylodis macrocephalae: strengthening the spleen and replenishing qi, the effect of eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.

Poria cocos: edema and little urine, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear are used for.

Fushen: shortness of breath of having a guilty conscience, invigorating the spleen benefit temperature are controlled.

Coloured malt: dyspepsia, abdominal distention, spleen eating less.

Fry rice sprout: spleen benefiting and stimulating the appetite, and in help digestion.

RHIIZOMA DIOSCOREAE from Henan of China: nourishing kidney-nourishing, stomach invigorating resolving sputum, tonifying middle-Jiao and Qi, cold wind of dispelling, relieving palpitation mind, peace soul, long flesh marrow and other effects.

The dried immature fruit of citron orange: internal stagnation；Feeling of fullness distending pain；Constipation；Weight after rush down dysentery.

Full Snakegourd Fruit: clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizing dryness and lubricating intestine

Caulis perllae: regulating the flow of QI to ease the stomach, analgesic, miscarriage prevention.Bored, the gastral cavity pain for chest diaphragm ruffian, belch vomiting, threatened abortion.

Dried orange peel: being used for abdominal fullness and distention, and deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.

Umbellate pore furgus: clearing damp and promoting diuresis.Control difficult urination, oedema, diarrhea, stranguria with turbid discharge, leukorrhagia.

Pinellia: stopping nausea and vomiting by lowering the adverse flow of QI.

Semen coicis: advantageous water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, the effect of detoxicating and resolving a mass.

Paniculate swallowwort: wind-expelling pain-stopping, removing toxicity for detumescence, warming and activating meridian.

Fiveleaf akebia fruit: liver-smoothing, qi-regulating, promoting blood circulation, removing blood stasis and acesodyne, relieving restlessness diuresis.

Radix glycyrrhizae preparata: and middle emergency, moistening lung, removing toxic substances, coordinating the drug actions of a prescription.

After the definition of " collaboration improves " can be understood as several medicinal material combinations in the present invention, drug effect is relative to exclusive use When raising；Drug effect is more lasting；Composition generates unexpected effect in new prevention and treatment or healthcare field.

Inventor is found by experiment that composition of the invention has the function for the treatment of cancer of pancreas.These single doses pass through one After the composition of certainty ratio to human body effect beneficial effect be single dose it is incomparable.

Composition of the invention can also be processed into sustained release preparation or quick releasing formulation.The wherein pharmaceutically acceptable load Body or excipient are selected according to different dosage forms.Ordinary skill people of these carriers or excipient used for pharmaceutical field Member can determine.

The preparation method of oral solution, can with but be not only limited to following one kind, after such as mixing active principle, add decocting It boils, decoction liquor is filtered, obtain solution, acquired solution is concentrated to get medicinal extract, then gained medicinal extract is dissolved in medicinal extract weight 5-10 The concentration of times weight is to be stirred, quantitative separating obtains oral liquid formulations in the ethanol water according to poidometer 95%.

The preparation method of tablet is that active principle mixture is sieved, with prepare the common auxiliary agent of tablet and crush, sufficiently After mixing, 40-80 mesh screen is crossed, it is by tabletting that the direct machine of dry powder is tabletted.

The preparation process of capsule preparations can be that active principle mixture is sieved, with prepare the common auxiliary agent of tablet After crushing, being sufficiently mixed uniformly, 40-80 mesh screen is crossed, it is dry by granulation, capsule is filled after the processes such as whole grain, is polished, packaging, i.e., Obtain finished product.

Beneficial effects of the present invention:

The present invention can treat cancer of pancreas (weakness of the spleen and stomach), curative effect affirmative, price vast, simple and easy to do with audient Feature cheap, easy to spread.The present invention innovatively proposes for the first time: the occurrence and development of cancer of pancreas and the dystrophy day after tomorrow, diet lose It adjusts, the gene mutation that seven feelings pent-ups induce, body's immunity is out of control closely related.Suffer from the deficiency of vital energy after cancer and strongly fragrant, bile excretion It is obstructed, so that there are the inverse random complex situations of yang blood and qi, but middle burnt dysfunction of spleen and stomach is its key, spleen deficiency is then wooden strongly fragrant, soil Empty then give birth to wet, qi depression to blood stasis and wetting phase knot block biliary tract into disease product, and bile is excessive into jaundice.Mass located in the upper or lower abdomen contamination, long then gas consumption Hurt just, the more impairment of the spleen.Therefore, only regulate and control the hinge of the taste day after tomorrow slightly, congenital to promote the day after tomorrow, regulating the qi flowing in the channels is to adjust the stasis of blood, while power Keep away and grow in greasy wound, sending an expedition against wound just, join on the basis of improve the taste day after tomorrow with qi-regulating, dampness elimination, disperse accumulation method, ability medicine is pertinent Qi, could control progression of the disease by transferring immune, the recovery function of body itself, extension Patients with Pancreatic Cancer life cycle, It improves the quality of living.It adjusts spleen suppression pancreas mixture energy invigorating the spleen for eliminating dampness and neutralizes drop, qi-regulating disperse accumulation, on the basis of improving the taste day after tomorrow, Qi-regulating, dampness elimination, disperse accumulation cure mainly the diseases such as abdominal pain, abdominal distension, jaundice, the loss of appetite of cancer of pancreas.

The effective component of pharmaceutical composition of the present invention is Radix Codonopsis, rhizoma atractylodis macrocephalae, Poria cocos, fushen, coloured malt, fries rice sprout, Huai Shan Medicine, the dried immature fruit of citron orange, full Snakegourd Fruit, caulis perllae, dried orange peel, umbellate pore furgus, pinellia, semen coicis, paniculate swallowwort, fiveleaf akebia fruit and radix glycyrrhizae preparata.The Chinese traditional medicine composition Object can be used for treating cancer of pancreas, the beneficial effect which acts on human body be single dose it is incomparable.The medicine The simple production process of object is easy to take, is significant in efficacy, is a kind of Chinese medicine composition of ideal treatment cancer of pancreas.

Specific embodiment

Below with reference to embodiment, the present invention will be further described, and but the scope of the present invention is not limited thereto:

Embodiment 1

Bulk pharmaceutical chemicals composition:

Radix Codonopsis 10g, rhizoma atractylodis macrocephalae 10g, 12g parts of Poria cocos, fushen 12g, coloured malt 20g, rice sprout 20g, RHIIZOMA DIOSCOREAE from Henan of China 15g, trifoliate orange are fried Real 10g, full Snakegourd Fruit (mass ratio of PERICARPIUM TRICHOSANTHIS and Snakegourd Seed is 1:1) 10g, caulis perllae 10g, dried orange peel 6g, umbellate pore furgus 30g, pinellia 12g, semen coicis 20g, paniculate swallowwort 30g, fiveleaf akebia fruit 30g and radix glycyrrhizae preparata 6g.

8 times of quality water of above-mentioned raw materials medicine are added in the preparation method of compound Chinese medicinal preparation, impregnate 0.5 hour, and it is small to decoct 1.5 When, it decocts 2 times.

Embodiment 2

Bulk pharmaceutical chemicals composition:

Radix Codonopsis 20g, rhizoma atractylodis macrocephalae 20g, Poria cocos 24g, fushen 24g, coloured malt 40g, rice sprout 40g, RHIIZOMA DIOSCOREAE from Henan of China 30g, the dried immature fruit of citron orange are fried 20g, full Snakegourd Fruit 20g, caulis perllae 20g, dried orange peel 12g, umbellate pore furgus 60g, pinellia 24g, semen coicis 40g, paniculate swallowwort 60g, fiveleaf akebia fruit 60g With radix glycyrrhizae preparata 12g.

8 times of amount water of above-mentioned raw materials medicine are added in the preparation method of compound Chinese medicinal preparation, impregnate 0.5 hour, decoct 1.5 hours, It decocts 2 times.

Embodiment 3

Bulk pharmaceutical chemicals composition:

Radix Codonopsis 30g, rhizoma atractylodis macrocephalae 30g, Poria cocos 36g, fushen 36g, coloured malt 60g, rice sprout 60g, RHIIZOMA DIOSCOREAE from Henan of China 45g, the dried immature fruit of citron orange are fried 30g, full Snakegourd Fruit 30g, caulis perllae 30g, dried orange peel 18g, umbellate pore furgus 90g, pinellia 36g, semen coicis 60g, paniculate swallowwort 90g, fiveleaf akebia fruit 90g With radix glycyrrhizae preparata 18g.

8 times of amount water of above-mentioned raw materials medicine are added in the preparation method of compound Chinese medicinal preparation, impregnate 0.5 hour, decoct 1.5 hours, It decocts 2 times.

Comparative example 1

Other conditions are with embodiment 1, in addition to lacking fushen, coloured malt in component and frying rice sprout.

Performance data:

Amount to case about 1000 from 01 month in December, 2016 in 2001, preferable curative effect is achieved, wherein there is clinic Data it is statistics available be 720.

Observation index: (1) clinical cardinal symptom (S): observation patient clinical cardinal symptom, including abdominal pain, abdominal distension, jaundice, food The symptoms such as depressed, bulging (ascites), fever are intended to, are divided into 4 grades: asymptomatic (0), slight (+), moderate (++), severe (+++), (+) It is denoted as 2 points.Syndrome Scale is compared pretherapy and post-treatment total mark referring to " new Chinese medicine guideline of clinical investigations ", according to Therapeutic index judges curative effect, S1 (effective): integral reduces >=70%；S2 (effective): integral reduces >=30%；S3 (invalid): product Divide and reduces < 30%.(2) knurl (T): complete incidence graph (CR): visible lesion completely disappeared, more than 1 month；Alleviate part (PR): 50% or more mass reduction, time are no less than 4 weeks；Unchanged (NC): mass reduction is not as good as 50% or increase is less than 25%；Be in progress (PD): one or more lesions increase 25% or more or new lesion occur.Determine T1 (effective): CR+PR；T2 (has Effect): NC；T3 (invalid): PD.(3) life quality (K): using Karnofsky standards of grading, and pretherapy and post-treatment row life quality is sentenced It is fixed.K1 (effective): than improving >=20 points before treatment after treatment；K2 (effective): than improving >=10 points before treatment after treatment；K3 (nothing Effect): it is more preceding than treatment without raising after treatment.(4) weight (G): survey weight 2 times (continuous 2 days) be averaged before and after treatment.G1 is (aobvious Effect): weight gain >=1.5kg before relatively being treated after treatment；G2 (effective): weight gain >=1.0kg before relatively being treated after treatment；G3 (invalid): weight without increase or increases less than 1kg before relatively treating after treatment.(5) tumour, which is put, exempts from (I): pretherapy and post-treatment row CA-199 Detection, and be compared.I1 (effective): >=50% is reduced before relatively treating after treatment or is dropped in normal range (NR), I2 (effective): is controlled >=25%, I3 (invalid) is reduced before relatively treating after treatment: < 25% is reduced before relatively treating after treatment, even it increases.(6) whole curative effect: Obvious income: in S1, T1-2, K, G, I one or more than one for 1 or three be 2；Income: two in S1, T2, K, G, I ≤2；S2, T2, K, G, I≤2；Not income: These parameters are not reached.(7) survival rate.

Treatment results:

Chinese medicine composition after patient's oral decoction of embodiment 1 daily, each 200ml, 2 times a day.Clinical effectiveness is as follows:

(1) clinical cardinal symptom (S): 180 patients, S1 (effective) 55, S2 (effective) 108, S3 (invalid) 17, Total effective rate 90.56%.

(2) knurl (T): 180 patients, T1 (effective) 10, T2 (effective) 135, T3 (invalid) 35, total effective rate 80.56%.

(3) life quality (K): 180 patients, K1 (effective) 53, K2 (effective) 109, K3 (invalid) 18 always have Efficiency 90.00%.

(4) weight (G): 180 patients, G1 (effective) 48, G2 (effective) 105, G3 (invalid) 27, total effective rate 85.00%.

(5) tumour, which is put, exempts from (I): 180 patients, I1 (effective) 11, I2 (effective) 128, I3 (invalid) 41 always have Efficiency 77.22%.

(6) whole curative effect: 180 patients, hence it is evident that income 50, income 97, not income 33, overall yield 81.67%.(7) survival rate: 180 patients, 1 year survival rate 56.67% (102/180), 2 years survival rates 43.89% (79/ 180), triennial deposits rate 21.67% (39/180), 5 years survival rates 8.33% (15/180).

Chinese medicine composition after patient's oral decoction of embodiment 2 daily, each 200ml, 2 times a day.Clinical effectiveness is as follows:

(1) clinical cardinal symptom (S): 180 patients, S1 (effective) 60, S2 (effective) 100, S3 (invalid) 20, Total effective rate 88.89%.

(2) knurl (T): 180 patients, T1 (effective) 12, T2 (effective) 140, T3 (invalid) 28, total effective rate 84.44%.

(3) life quality (K): 180 patients, K1 (effective) 59, K2 (effective) 103, K3 (invalid) 18 always have Efficiency 90.00%.

(4) weight (G): 180 patients, G1 (effective) 52, G2 (effective) 110, G3 (invalid) 18, total effective rate 90.00%.

(5) tumour, which is put, exempts from (I): 180 patients, I1 (effective) 15, I2 (effective) 120, I3 (invalid) 45 always have Efficiency 75.00%.

(6) whole curative effect: 180 patients, hence it is evident that income 63, income 87, not income 30, overall yield 83.33%.(7) survival rate: 180 patients, 1 year survival rate 58.33% (105/180), 2 years survival rates 45.56% (82/ 180), triennial deposits rate 23.33% (42/180), 5 years survival rates 10% (18/180).

Chinese medicine composition after patient's oral decoction of embodiment 3 daily, each 200ml, 2 times a day.Clinical effectiveness is as follows:

(1) clinical cardinal symptom (S): 180 patients, S1 (effective) 65, S2 (effective) 101, S3 (invalid) 14, Total effective rate 92.22%.

(2) knurl (T): 180 patients, T1 (effective) 9, T2 (effective) 131, T3 (invalid) 40, total effective rate 77.78%.

(3) life quality (K): 180 patients, K1 (effective) 49, K2 (effective) 107, K3 (invalid) 24 always have Efficiency 86.67%.

(4) weight (G): 180 patients, G1 (effective) 68, G2 (effective) 95, G3 (invalid) 17, total effective rate 90.56%.

(5) tumour, which is put, exempts from (I): 180 patients, I1 (effective) 8, I2 (effective) 130, I3 (invalid) 42, total effective Rate 76.67%.

(6) whole curative effect: 180 patients, hence it is evident that income 59, income 90, not income 31, overall yield 82.78%.(7) survival rate: 180 patients, 1 year survival rate 62.22% (112/180), 2 years survival rates 48.33% (87/ 180), triennial deposits rate 16.11% (29/180), 5 years survival rates 10.56% (19/180).

Chinese medicine composition after the daily decoction of oral contrast example 1 of patient, each 200ml, 2 times a day.Clinical effectiveness is as follows:

(1) clinical cardinal symptom (S): 180 patients, S1 (effective) 40, S2 (effective) 78, S3 (invalid) 62, always Effective percentage 65.56%.

(2) knurl (T): 180 patients, T1 (effective) 8, T2 (effective) 95, T3 (invalid) 73, total effective rate 57.22%.

(3) life quality (K): 180 patients, K1 (effective) 33, K2 (effective) 79, K3 (invalid) 68 are total effective Rate 62.22%.

(4) weight (G): 180 patients, G1 (effective) 36, G2 (effective) 75, G3 (invalid) 69, total effective rate 61.67%.

(5) tumour, which is put, exempts from (I): 180 patients, I1 (effective) 6, I2 (effective) 108, I3 (invalid) 66, total effective Rate 63.33%.

(6) whole curative effect: 180 patients, hence it is evident that income 20, income 97, not income 63, overall yield 65%.

(7) survival rate: 180 patients, 1 year survival rate 45.56% (82/180), 2 years survival rates 38.33% (69/180), Triennial deposits rate 10.56% (19/180), 5 years survival rates 5% (9/180).

Claims (6)

1. a kind of Chinese medicine composition for treating cancer of pancreas, it is characterised in that: the effective component and each component of the Chinese medicine composition are used Measure as follows: 1~80 part of Radix Codonopsis, 1~50 part of Poria cocos, 1~50 part of fushen, 1~80 part of coloured malt, fries rice sprout at 1~60 part of rhizoma atractylodis macrocephalae 1~80 part, 1~60 part of RHIIZOMA DIOSCOREAE from Henan of China, 1~50 part of the dried immature fruit of citron orange, 1~50 part of full Snakegourd Fruit, 1~50 part of caulis perllae, 1~30 part of dried orange peel, umbellate pore furgus 1 ~90 parts, 1~50 part of pinellia, 1~60 part of semen coicis, 1~90 part of paniculate swallowwort, 1~90 part of fiveleaf akebia fruit and radix glycyrrhizae preparata 1~30 Part.

2. the Chinese medicine composition for the treatment of cancer of pancreas according to claim 1, it is characterised in that: 1~30 part of Radix Codonopsis, rhizoma atractylodis macrocephalae 1~30 part, 10~40 parts of Poria cocos, 10~40 parts of fushen, 10~60 parts of coloured malt, stir-fry 10~60 parts of rice sprout, RHIIZOMA DIOSCOREAE from Henan of China 10~45 Part, 10~30 parts of the dried immature fruit of citron orange, 10~30 parts of full Snakegourd Fruit, 10~30 parts of caulis perllae, 6~18 parts of dried orange peel, 30~90 parts of umbellate pore furgus, pinellia 12 ~36 parts, 20~60 parts of semen coicis, 30~90 parts of paniculate swallowwort, 30~90 parts of fiveleaf akebia fruit and 6~18 parts of radix glycyrrhizae preparata.

3. the Chinese medicine composition for the treatment of cancer of pancreas according to claim 2, it is characterised in that: 10~30 parts of Radix Codonopsis, stir-fry are white 10~30 parts of art, 12~36 parts of Poria cocos, 12~36 parts of fushen, 20~60 parts of coloured malt, fry 20~60 parts of rice sprout, RHIIZOMA DIOSCOREAE from Henan of China 15~ 45 parts, 10~30 parts of the dried immature fruit of citron orange, 10~30 parts of full Snakegourd Fruit, 10~30 parts of caulis perllae, 6~18 parts of dried orange peel, 30~90 parts of umbellate pore furgus, pinellia 12~36 parts, 20~60 parts of semen coicis, 30~90 parts of paniculate swallowwort, 30~90 parts of fiveleaf akebia fruit and 6~18 parts of radix glycyrrhizae preparata.

4. the Chinese medicine composition for the treatment of cancer of pancreas according to claim 1-3, it is characterised in that: full Snakegourd Fruit is by melon Beach wormwood skin and Snakegourd Seed composition, and the mass ratio of PERICARPIUM TRICHOSANTHIS and Snakegourd Seed is 5~15:5~15.

5. the Chinese medicine composition for the treatment of cancer of pancreas according to claim 1-3, it is characterised in that: composition has After imitating ingredient mixing, pharmaceutically acceptable auxiliary material is added, clinically-acceptable dosage form is made；The dosage form is peroral dosage form Preparation.

6. the described in any item Chinese medicine compositions of claim 1-3 are as the purposes in preparation prevention and treatment pancreatic cancer drug.