CN105535839A - Traditional Chinese medicine tablets for treating colon cancer and preparation method thereof - Google Patents

Traditional Chinese medicine tablets for treating colon cancer and preparation method thereof Download PDF

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Publication number
CN105535839A
CN105535839A CN201610020528.4A CN201610020528A CN105535839A CN 105535839 A CN105535839 A CN 105535839A CN 201610020528 A CN201610020528 A CN 201610020528A CN 105535839 A CN105535839 A CN 105535839A
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rhizoma atractylodis
herba
chinese medicine
colon cancer
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任韶韶
李然
唐淑美
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Qingdao Tumour Hospital
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Qingdao Tumour Hospital
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Abstract

The invention belongs to the field of traditional Chinese medicine and particularly relates to traditional Chinese medicine tablets for treating colon cancer and a preparation method thereof. The tablets are prepared from, by weight, 6-8 parts of all-grass of polygunum chinense L., 8-10 parts of cortex magnoliae officinalis, 10-15 parts of rhizoma atractylodis macrocephalae, 10-15 parts of poria, 8-10 parts of herba eupatorii, 8-10 parts of netmeg, 8-10 parts of rhizoma atractylodis, 10-15 parts of radix pseudostellariae, 10-15 parts of liquorice roots, 25-30 parts of spreading hedyotis herbs, 15-20 parts of herba scutellariae barbatae, 10-15 parts of caulis sargentodoxae, 10-15 parts of boor's mustard herbs, 10-15 parts of parched rhizoma atractylodis macrocephalae, 10-15 parts of parched white peony roots, 10-15 parts of poria, 10-15 parts of manyflower solomonseal rhizomes, 15-20 parts of wood of cudrania tricuspidata (carr.) bur. ex lavallee, 15-20 parts of radix curcumae, 6-8 parts of carapax trionycis and 6-8 parts of ganoderma. The traditional Chinese medicine tablets can promote qi circulation to relieve pain, soften hard mass, disperse stasis, clear away heat and toxic materials, promote blood circulation to remove blood stasis, eliminate swelling and dispel toxin, an obvious inhibition effect is achieved on colon cancer cells, both the symptoms and root causes of the disease are treated, deficiency and excess are treated simultaneously, the interior and the exterior are both regulated, both the chronic pathogenic factors and the acute pathogenic factors are suppressed, immunity of the human body is greatly improved, no toxic or side effect can be caused to the human body, and the life of a patient is saved.

Description

A kind of Chinese medicinal tablet for the treatment of colon cancer and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicinal tablet for the treatment of colon cancer and preparation method thereof.
Background technology
Colon cancer is one of common malignant tumor, and be the common malignant tumor of digestive tract betiding colon site, be apt to occur in rectum and sigmoid colon intersection, its sickness rate occupies 4th ~ 6 of malignant tumor.Recently its sickness rate has the trend of rising.After its radical excision, 5 years survival rates are about 50%.Postoperative recurrence and transfer are the major reasons of its death.The method of the treatment colon cancer of generally acknowledging at present is performed the operation as master and is aided with chemotherapy, the Comprehensive Treatment of immunization therapy, Chinese medicine and other Supporting Therapy.Colorectal cancer patients is mostly above middle age, and its median age is 45 years old, about has the age of 5% patient below 30 years old.Colon cancer can be gone in ring along intestinal wall and be developed, and indulges footpath spread up and down or infiltrate to intestinal wall deep layer along intestinal tube, except except lymphatic vessel, blood flow transfer and local Invasion, and also can to intraperitoneal plantation or along suture, cut sides diffusion transfer.The clinical manifestation of colon cancer is different with its position, size of tumor place and histological type.Many early stage colorectal cancer patients can have no symptom clinically, but along with the development of the course of disease and the continuous increase of focus, the common sympton of a series of colon cancer can be produced, such as times of defecation increases, defecate band blood and mucus, stomachache, diarrhoea or constipation, intestinal obstruction and malaise, to lose weight and the symptom such as anemia.In recent years various places data display is along with the raising of living standards of the people, and the change of dietary structure, its sickness rate is in going up each trend year by year.
The Therapeutic Method of current colon cancer is based on excision and chemotherapy, and operative treatment easily recurs, and postoperative many complication has occurred.Chemotherapy easily produces gastrointestinal reaction, and side effect is obvious, fundamentally cannot solve the misery of patient.
Summary of the invention
According to the deficiencies in the prior art, the invention provides a kind of promoting the circulation of QI to relieve pain, softening the hard mass knot, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, loose swollen toxin expelling, to colon cancer cell, there is the obvious inhibiting Chinese medicine formula for the treatment of colon cancer and the preparation method of tablet thereof.
A kind of Chinese medicinal tablet for the treatment of colon cancer disclosed in this invention, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 6-8 part, Cortex Magnoliae Officinalis 8-10 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Poria 10-15 part, Herba Eupatorii 8-10 part, Semen Myristicae 8-10 part, Rhizoma Atractylodis 8-10 part, Radix Pseudostellariae 10-15 part, Radix Glycyrrhizae 10-15 part, Herba Hedyotidis Diffusae 25-30 part, Herba Scutellariae Barbatae 15-20 part, Caulis Sargentodoxae 10-15 part, Herba Thlaspis 10-15 part, Rhizoma Atractylodis Macrocephalae (parched) 10-15 part, Radix Paeoniae Alba (parched) 10-15 part, Poria 10-15 part, Rhizoma Polygonati 10-15 part, Lignum Cudraniae tricuspidatae 15-20 part, Radix Curcumae 15-20 part, Carapax Trionycis 6-8 part, Ganoderma 6-8 part.
Treat a Chinese medicinal tablet for colon cancer, preferably formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 7 parts, Cortex Magnoliae Officinalis 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 12 parts, Poria, Herba Eupatorii 9 parts, Semen Myristicae 9 parts, Rhizoma Atractylodis 9 parts, Radix Pseudostellariae 12 parts, 12 parts, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 27 parts, Herba Scutellariae Barbatae 17 parts, Caulis Sargentodoxae 12 parts of , Herba Thlaspiss 12 parts, Rhizoma Atractylodis Macrocephalae (parched) 12 parts, Radix Paeoniae Alba (parched) 13 parts, 13 parts, Poria, Rhizoma Polygonati 12 parts, Lignum Cudraniae tricuspidatae 17 parts, Radix Curcumae 18 parts, Carapax Trionycis 7 parts, Ganoderma 7 parts.
A kind of preparation method for the treatment of the Chinese medicinal tablet of colon cancer, step is as follows: be mixed in proportion by each for above-mentioned Chinese medicine raw medicinal material, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; The dry cream obtained is placed in super micron mill and pulverizes 2 ~ 3 hours, after pulverizing and sieving, obtain 300 order ~ 400 object micropowders; By the micropowders obtained, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, the tablet obtaining every sheet 0.15-0.18g made by granulate tabletting.
Instructions of taking: the morning, noon and afternoon, respectively once each 1-2 sheet, warm water took.It within 30 days, is a course for the treatment of.
Pharmacology analysis:
Herb Polygoni Chinensis: the micro-acid of taste, micro-puckery, cool in nature.Return Liver Channel, spleen channel.Can heat-clearing and toxic substances removing, dampness removing disappears stagnant, blood-cooling itch-relieving, improving acuity of vision and removing nebula.For dysentery, enteritis, dyspepsia, hepatitis, flu, tonsillitis, pharyngolaryngitis, diphtheria, pertussis, corneal nebula, colpitis mycotica, leucorrhea, mastitis, furuncle and phyma, children's's impetigo, eczema, venom.
Cortex Magnoliae Officinalis: bitter in the mouth, pungent, warm in nature.Return spleen, stomach, lung, large intestine channel.Can dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Can invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.Can promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Herba Eupatorii: acrid in the mouth, property is put down.Return spleen, stomach, lung meridian.Can removing dampness by means of aromatics, appetizing of being amusing, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass vomiting and nausea, sweet greasy in mouth, halitosis, sialism, heat-damp in summer table disease, feeling of fullness in the head is uncomfortable in chest.
Semen Myristicae: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, large intestine channel.Can warming middle-JIAO astringing intestine to stop diarrhea, promote qi circulation digestion promoting.For diarrhea of deficiency type, cold-dysentery, abdominal distention, lack of appetite is vomitted, and dyspepsia does not disappear.
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.Can be drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Radix Pseudostellariae: sweet in the mouth, micro-hardship, property is put down.Return spleen, lung meridian.Can replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.Tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Can invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Herba Hedyotidis Diffusae: sweet in the mouth, light, cool in nature.Return stomach, large intestine, small intestine meridian.Can heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis, furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria.
Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature.Return lung, liver, kidney channel.Can heat-clearing and toxic substances removing, blood stasis dispelling diuresis.For furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, edema, jaundice.
Caulis Sargentodoxae: bitter in the mouth, property is put down.Return large intestine, Liver Channel.Can heat-clearing and toxic substances removing, invigorate blood circulation, dispel the wind.For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.
Herba Thlaspis: bitter in the mouth, sweet, cold nature.Return liver, kidney channel.Can heat-clearing and toxic substances removing, inducing diuresis and reducing edema, and middle appetizing.For appendicitis, lung abscess, carbuncle furuncle and phyma poison, erysipelas, endometritis, leucorrhea, nephritis, cirrhotic ascites, infantile dyspepsia.
Rhizoma Atractylodis Macrocephalae (parched): bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Can invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Paeoniae Alba (parched): bitter in the mouth, acid, cold nature.Return liver, spleen channel.Can suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.Can promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Rhizoma Polygonati: sweet in the mouth, property is put down.Return spleen, lung, kidney channel.Can boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying.For weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, interior-heat is quenched one's thirst.
Lignum Cudraniae tricuspidatae: sweet in the mouth, warm in nature.Return liver, spleen channel.Can removing stasis to stop bleeding, liver heat removing and eyesight improving, preventing the attack (or recurrence) of malaria.For metrorrhagia, fly silk and enter order, malaria.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.Can regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Carapax Trionycis: salty in the mouth, cold nature.Return liver, kidney channel.Can nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea , WEIJIA, chronic malaria malaria with splenomegaly.
Ganoderma: sweet in the mouth, property is put down.GUIXIN, lung, liver, kidney channel.Can invigorating QI and tranquilization, relieving cough and asthma.For dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma.
Chinese medicine of the present invention can promoting the circulation of QI to relieve pain, softening the hard mass knot, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, loose swollen toxin expelling, to colon cancer cell, there is obvious inhibitory action, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical tune, emergency is taken in concurrently, greatly improves immunity of human body itself, and toxic and side effects can not be produced to human body, save patients ' lives.
Now collect 90 colorectal cancer patients, take this tablet, the morning, noon and afternoon, respectively once each 1-2 sheet, warm water took.
Outcome measure:
Effective: tumor body disappears or tumor body significantly reduces, body constitution strengthens, diet, rest and defecate normal, and patient feels better, happy, in high spirits.
Effective: tumor body diminishes or has no increase, and body constitution strengthens to some extent, diet, rest and stool are improved, and patient heart is comparatively happy, and spirit better.
Invalid: disease is without any change, and symptom is as front, or colon tumor tumor body increases to some extent.
It within 30 days, is a course for the treatment of.After using 3 course for the treatment of Chinese medicines of the present invention, statistical result is as follows:
Case load Effective number Obvious effective rate Significant figure Invalid number Total effective rate
90 82 91.1% 5 3 96.7%
As seen from the above table, after pharmaceutical treatment of the present invention, effective 82 examples, account for 91.1%, and effective 5 examples, account for 5.6%, and invalid 3 examples, account for 3.3%, overall efficiency is 96.7%.As can be seen here, the treatment of the present invention to colon cancer has good effect.
Attached several routine case is described further:
Case 1:
Wu, female, 48 years old, times of defecation increased, be with blood 3 months.Without obvious inducement before 3 months, defecation frequency increases, and 3-6 times/day is shapeless, gap zone kermesinus bloodstain.In having, lower abdominal pain, without obvious abdominal distention and nausea and vomiting.Without heating, feed can.Recently obviously weak, weight loss.Be colon cancer at hospital diagnosis afterwards, after taking 2 courses for the treatment of of Chinese medicine of the present invention, the state of an illness is alleviated to some extent, is originally spirit, appetite takes a turn for the better, then the pain relief of persistence, occasionally have blood in stool, after continuing 2 courses for the treatment of of use, disease is significantly improved, stool is normal, without inadaptation, finally take 2 courses for the treatment of and consolidate, follow up a case by regular visits to 2 years without recurrence.
Case 2:
Zhang, female, 61 years old, was diagnosed as colon cancer through hospital before 2 years, through many hospitalize DeGrains, take Chinese medicine composition of the present invention after being introduced, serve on after 2 courses for the treatment of, CT examination tumor body diminishes to some extent, and diet, rest and stool improve, and the mental status is better.After continuing to take 3 months, CT examination tumor body disappears, and body constitution strengthens, and diet, rest and stool are normal, without any ill symptoms, in high spirits.Recurrence is had no by following up a case by regular visits to 1 year.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail, but the present invention is not limited to specific embodiment.
Embodiment 1:
Treat a Chinese medicinal tablet for colon cancer, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 8 parts, Cortex Magnoliae Officinalis 8 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, 10 parts, Poria, Herba Eupatorii 10 parts, Semen Myristicae 8 parts, Rhizoma Atractylodis 10 parts, Radix Pseudostellariae 10 parts, 15 parts, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 25 parts, Herba Scutellariae Barbatae 20 parts, Caulis Sargentodoxae 10 parts of , Herba Thlaspiss 15 parts, Rhizoma Atractylodis Macrocephalae (parched) 10 parts, Radix Paeoniae Alba (parched) 15 parts, 10 parts, Poria, Rhizoma Polygonati 15 parts, Lignum Cudraniae tricuspidatae 15 parts, Radix Curcumae 20 parts, Carapax Trionycis 6 parts, Ganoderma 8 parts.
Embodiment 2:
Treat a Chinese medicinal tablet for colon cancer, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 6 parts, Cortex Magnoliae Officinalis 10 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 15 parts, Poria, Herba Eupatorii 8 parts, Semen Myristicae 10 parts, Rhizoma Atractylodis 8 parts, Radix Pseudostellariae 15 parts, 10 parts, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 30 parts, Herba Scutellariae Barbatae 15 parts, Caulis Sargentodoxae 15 parts of , Herba Thlaspiss 10 parts, Rhizoma Atractylodis Macrocephalae (parched) 15 parts, Radix Paeoniae Alba (parched) 10 parts, 15 parts, Poria, Rhizoma Polygonati 10 parts, Lignum Cudraniae tricuspidatae 20 parts, Radix Curcumae 15 parts, Carapax Trionycis 8 parts, Ganoderma 6 parts.
Embodiment 3:
Treat a Chinese medicinal tablet for colon cancer, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 7 parts, Cortex Magnoliae Officinalis 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 12 parts, Poria, Herba Eupatorii 9 parts, Semen Myristicae 9 parts, Rhizoma Atractylodis 9 parts, Radix Pseudostellariae 12 parts, 12 parts, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 27 parts, Herba Scutellariae Barbatae 17 parts, Caulis Sargentodoxae 12 parts of , Herba Thlaspiss 12 parts, Rhizoma Atractylodis Macrocephalae (parched) 12 parts, Radix Paeoniae Alba (parched) 13 parts, 13 parts, Poria, Rhizoma Polygonati 12 parts, Lignum Cudraniae tricuspidatae 17 parts, Radix Curcumae 18 parts, Carapax Trionycis 7 parts, Ganoderma 7 parts.
Embodiment 4:
A kind of preparation method for the treatment of the Chinese medicinal tablet of colon cancer, step is as follows: be mixed in proportion by each for the Chinese medicine in embodiment 1 raw medicinal material, adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 85%, reflux 2 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 1 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; The dry cream obtained is placed in super micron mill and pulverizes 2 ~ 3 hours, after pulverizing and sieving, obtain 300 object micropowders; By the micropowders obtained, add the starch relative to the microcrystalline Cellulose of its quality 0.1 times, 0.15 times of lactose and 0.2 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 times, the tablet obtaining every sheet 0.15 made by granulate tabletting.
Instructions of taking: the morning, noon and afternoon, respectively once each 1, warm water took.It within 30 days, is a course for the treatment of.
Embodiment 5:
A kind of preparation method for the treatment of the Chinese medicinal tablet of colon cancer, step is as follows: be mixed in proportion by each for the Chinese medicine in embodiment 2 raw medicinal material, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 90%, reflux 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 3 times again, reflux 3 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; The dry cream obtained is placed in super micron mill and pulverizes 3 hours, after pulverizing and sieving, obtain 400 object micropowders; By the micropowders obtained, add the starch relative to the microcrystalline Cellulose of its quality 0.3 times, 0.3 times of lactose and 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.04 times, the tablet obtaining every sheet 0.18g made by granulate tabletting.
Instructions of taking: the morning, noon and afternoon, respectively once each 2, warm water took.It within 30 days, is a course for the treatment of.
Embodiment 6:
A kind of preparation method for the treatment of the Chinese medicinal tablet of colon cancer, step is as follows: be mixed in proportion by each for the Chinese medicine in embodiment 3 raw medicinal material, adding relative to the determining alcohol of mixture quality 4.5 times is the ethanol of 88%, reflux 3 hours, obtains the first extracting solution after filtering; It is the ethanol of 93% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2.5 times again, reflux 2 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; The dry cream obtained is placed in super micron mill and pulverizes 2.5 hours, after pulverizing and sieving, obtain 350 object micropowders; By the micropowders obtained, add the starch relative to the microcrystalline Cellulose of its quality 0.2 times, 0.2 times of lactose and 0.3 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.03 times, the tablet obtaining every sheet 0.16 made by granulate tabletting.
Instructions of taking: the morning, noon and afternoon, respectively once each 2, warm water took.It within 30 days, is a course for the treatment of.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.

Claims (3)

1. treat the Chinese medicinal tablet of colon cancer for one kind, it is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 6-8 part, Cortex Magnoliae Officinalis 8-10 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Poria 10-15 part, Herba Eupatorii 8-10 part, Semen Myristicae 8-10 part, Rhizoma Atractylodis 8-10 part, Radix Pseudostellariae 10-15 part, Radix Glycyrrhizae 10-15 part, Herba Hedyotidis Diffusae 25-30 part, Herba Scutellariae Barbatae 15-20 part, Caulis Sargentodoxae 10-15 part, Herba Thlaspis 10-15 part, Rhizoma Atractylodis Macrocephalae (parched) 10-15 part, Radix Paeoniae Alba (parched) 10-15 part, Poria 10-15 part, Rhizoma Polygonati 10-15 part, Lignum Cudraniae tricuspidatae 15-20 part, Radix Curcumae 15-20 part, Carapax Trionycis 6-8 part, Ganoderma 6-8 part.
2. a kind of Chinese medicinal tablet for the treatment of colon cancer according to claim 1, is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Herb Polygoni Chinensis 7 parts, Cortex Magnoliae Officinalis 9 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, 12 parts, Poria, Herba Eupatorii 9 parts, Semen Myristicae 9 parts, Rhizoma Atractylodis 9 parts, Radix Pseudostellariae 12 parts, 12 parts, Radix Glycyrrhizae, Herba Hedyotidis Diffusae 27 parts, Herba Scutellariae Barbatae 17 parts, Caulis Sargentodoxae 12 parts of , Herba Thlaspiss 12 parts, Rhizoma Atractylodis Macrocephalae (parched) 12 parts, Radix Paeoniae Alba (parched) 13 parts, 13 parts, Poria, Rhizoma Polygonati 12 parts, Lignum Cudraniae tricuspidatae 17 parts, Radix Curcumae 18 parts, Carapax Trionycis 7 parts, Ganoderma 7 parts.
3. the preparation method of the Chinese medicinal tablet of a treatment colon cancer according to claim 1, it is characterized in that step is as follows: be mixed in proportion by each for above-mentioned Chinese medicine raw medicinal material, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; The dry cream obtained is placed in super micron mill and pulverizes 2 ~ 3 hours, after pulverizing and sieving, obtain 300 order ~ 400 object micropowders; By the micropowders obtained, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, the tablet obtaining every sheet 0.15-0.18g made by granulate tabletting.
CN201610020528.4A 2016-01-13 2016-01-13 Traditional Chinese medicine tablets for treating colon cancer and preparation method thereof Pending CN105535839A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110215495A (en) * 2019-07-15 2019-09-10 李国伦 A kind of drug improved the immunity of the human body
CN112494541A (en) * 2020-12-03 2021-03-16 无锡市第二人民医院 Preparation process of poriferous retinal detachment preparation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102370939A (en) * 2010-08-18 2012-03-14 郑国红 Body resistance-strengthening and anticancer traditional Chinese medicine
CN102961648A (en) * 2012-12-21 2013-03-13 戴玲玲 Chinese herbal medicine compound preparation for treating advanced colorectal cancer
CN103908611A (en) * 2014-04-25 2014-07-09 王小艳 Traditional Chinese medicine preparation for treating colon cancer and preparation method of traditional Chinese medicine preparation
CN104721702A (en) * 2015-04-09 2015-06-24 山东省立医院 Traditional Chinese medicine for treating colorectal cancer

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Publication number Priority date Publication date Assignee Title
CN102370939A (en) * 2010-08-18 2012-03-14 郑国红 Body resistance-strengthening and anticancer traditional Chinese medicine
CN102961648A (en) * 2012-12-21 2013-03-13 戴玲玲 Chinese herbal medicine compound preparation for treating advanced colorectal cancer
CN103908611A (en) * 2014-04-25 2014-07-09 王小艳 Traditional Chinese medicine preparation for treating colon cancer and preparation method of traditional Chinese medicine preparation
CN104721702A (en) * 2015-04-09 2015-06-24 山东省立医院 Traditional Chinese medicine for treating colorectal cancer

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110215495A (en) * 2019-07-15 2019-09-10 李国伦 A kind of drug improved the immunity of the human body
CN112494541A (en) * 2020-12-03 2021-03-16 无锡市第二人民医院 Preparation process of poriferous retinal detachment preparation
CN112494541B (en) * 2020-12-03 2022-03-08 无锡市第二人民医院 Preparation process and application of preparation for hole-source retinal detachment reduction operation

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Application publication date: 20160504