CN104740426A - Traditional Chinese medicine formula for treating chronic appendicitis and preparation method of tablet thereof - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a traditional Chinese medicine formula for treating chronic appendicitis and a preparation method of a tablet thereof. The traditional Chinese medicine formula is prepared from the following traditional Chinese medicines in parts by weight: 5-10 parts of rheum officinale, 10-15 parts of peach kernels, 10-15 parts of moutan barks, 10-20 parts of semen coicis, 8-10 parts of radix paeoniae alba, 8-10 parts of elecampane, 10-15 parts of dried radix rehmanniae, 10-15 parts of salviae miltiorrhizae, 12-18 parts of angelica sinensis, 10-15 parts of mirabilite, 10-15 parts of olibanum, 20-30 parts of patrinia, 5-15 parts of liquorice, 20-30 parts of Chinese violet, 10-15 parts of fructus forsythia, 10-15 parts of scutellaria baicalensis, 10-15 parts of fructus aurantii, 10-15 parts of roots of common peony, 10-15 parts of flowers carthami and 10-20 parts of dandelions. The traditional Chinese medicine formula provided by the invention has the advantages that the traditional Chinese medicines used in the traditional Chinese medicine formula meets stipulation of Chinese pharmacopoeia, are safe and reliable, and can be used for tonifying qi and blood, clearing heat and removing obstruction of fu-organs and regulating qi to alleviate pain so as to improve appendicitis symptoms, control progression of disease and enhance the immunity of the patient, and the traditional Chinese medicine formula further can be used for promoting qi to activate blood, moistening dryness and relieving restlessness, improving the appetite of the patient and enhancing the physical power of the patient.

Description

A kind ofly treat the Chinese medicine formula of chronic appendicitis and the preparation method of tablet thereof

Technical field

The invention belongs to technical field of Chinese medicines, particularly a kind ofly treat the Chinese medicine formula of chronic appendicitis and the preparation method of tablet thereof.

Background technology

Appendicitis is a kind of clinical common surgery abdomen disease, is that the inflammatory that formed because of many factors changes, is surgical common disease, can betides any age, be more common in person between twenty and fifty, have acute and chronic appendicitis point.If appendicitis treatment is not thorough, easily cause intestinal to suppurate or perforation, consequence is very serious.

At present, for acute appendicitis, Therapeutic Principle is upper by operation by appendectomy, thoroughly should effect a radical cure.

For chronic appendicitis, can carry out Chinese and western drugs treatment, and regular western medicine expectant treatment, treatment time is long, and medical expense is high, and side effect is comparatively large and patient is painful and easily recur.Compare western medical treatment, Chinese traditional treatment is a more excellent scheme, but in view of current tcm prescription be all accumulate long-pending catharsis of implementing for large intestine damp and hot to expel the heat-evil, temporary relief swelling pain sense, patient thinks that disease is cured.But stagnation of QI-blood is from dissolving at all, through after a while, the stasis of blood is stagnant may again can heat-transformation, and swelling pain will occur again, causes obstinate, easily recurrence after treatment in perception.

The Chinese medicine preparation also not having a kind of gentleness effectively to treat chronic appendicitis at present can solve the problem.

Summary of the invention

The object of this invention is to provide that a kind of gentleness is effective, medication is few, expense is low, recover the Chinese medicine formula for the treatment of chronic appendicitis early and the preparation method of tablet thereof.

The invention provides a kind of Chinese medicine formula for the treatment of chronic appendicitis, formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 5-10 part, Semen Persicae 10-15 part, Cortex Moutan 10-15 part, Semen Coicis 10-20 part, Radix Paeoniae Alba 8-10 part, Radix Aucklandiae 8-10 part, Radix Rehmanniae 10-15 part, Radix Salviae Miltiorrhizae 10-15 part, Radix Angelicae Sinensis 12-18 part, Natrii Sulfas 10-15 part, Olibanum 10-15 part, Herba Patriniae 20-30 part, Radix Glycyrrhizae 5-15 part, Herba Violae 20-30 part, Fructus Forsythiae 10-15 part, Radix Scutellariae 10-15 part, Fructus Aurantii 10-15 part, Radix Paeoniae Rubra 10-15 part, Flos Carthami 10-15 part, Herba Taraxaci 10-20 part.

Treat a Chinese medicine formula for chronic appendicitis, preferably formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 7 parts, 12 parts, Semen Persicae, Cortex Moutan 12 parts, Semen Coicis 15 parts, the Radix Paeoniae Alba 9 parts, the Radix Aucklandiae 9 parts, 12 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 12 parts, Radix Angelicae Sinensis 15 parts, 12 parts, Natrii Sulfas, Olibanum 12 parts, Herba Patriniae 25 parts, 10 parts, Radix Glycyrrhizae, Herba Violae 25 parts, Fructus Forsythiae 12 parts, Radix Scutellariae 12 parts, Fructus Aurantii 12 parts, Radix Paeoniae Rubra 12 parts, 12 parts, Flos Carthami, Herba Taraxaci 15 parts.

Treat a tableting methods for the Chinese medicine formula of chronic appendicitis, step is as follows:

1) be mixed in proportion by each for above-mentioned Chinese medicine raw medicinal material, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract;

2) by the first step obtain dry cream be placed in super micron mill pulverize 2 ~ 3 hours, after pulverizing and sieving, obtain 300 ~ 400 object micropowders;

3) by the micropowders of second step acquisition, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, tablet made by granulate tabletting.

Instructions of taking: every day 3 times, each 2-4 sheet, one after each meal, warm water takes, and within 10 days, is a course for the treatment of.

Pharmacology analysis:

Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature, return spleen, stomach, large intestine, liver, pericardium channel.Can purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.For conjunctival congestion pharyngeal swelling, pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding, and has stasis of blood hemorrhage for heat in blood.

Semen Persicae: bitter in the mouth, sweet, property is put down.GUIXIN, liver, large intestine channel.Can blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea ， WEIJIA mass in the abdomen, injury from falling down, dryness of the intestine constipation.Cure mainly: lump in the abdomen lumps, lung abscess acute appendicitis, tumbling down is grieved, amenorrhea dysmenorrhea, and puerperal, stasis of blood pain waited disease, benefiting QI for activating blood circulation, disperse blood stasis and dredge collateral, expansion cardiovascular and cerebrovascular vessel, blood fat reducing, bitter but sweet flavor and property are put down, and can enter conscience large intestine, and blood circulation promoting and blood stasis dispelling effect is very wide, availablely control the various worn-out disease of stagnation of blood stasis.

Cortex Moutan: bitter in the mouth, cold in nature, GUIXIN, liver, kidney channel.Clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.

Semen Coicis: sweet in the mouth, cold nature, nontoxic.Function spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal; For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.

The Radix Paeoniae Alba: bitter in the mouth is sour, cold in nature, enters liver, spleen channel, nourishing blood to suppress the hyperactive liver, pain relieving in slow, yin fluid astringing receives antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency etc.

The Radix Aucklandiae: acrid in the mouth, hardship, warm in nature, return spleen, stomach, liver, large intestine channel.The pain relieving of function warming middle-JIAO to promote flow of QI, strengthening the spleen to promote digestion intestinal stasis relieving.Cure mainly fullness and distention in the chest and hypochondrium, abdominal distention, tell and have loose bowels, heavy after dysentery, food stagnation does not disappear, anorexia, and colic of cold type is suffered from abdominal pain, edema etc.

The Radix Rehmanniae: bitter in the mouth, dry, cool in nature, clearing away heat and promoting production of body fluid, after cool, hemostasis, yin nourishing, promotes the production of body fluid; For calentura excessive thirst, send out speckle dermexanthesis, yin asthenia generating intrinsic heat, haematemesis, epistaxis etc.

Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.

Radix Angelicae Sinensis: sweet in the mouth, pungent, warm in nature, returns liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.

Natrii Sulfas: salty in the mouth, hardship, cold in nature, return stomach, large intestine channel.Can purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; External treatment acute mastitis, swelling and pain of hemorrhoid.

Olibanum: acrid in the mouth, heat, micro-poison; Enter the heart, liver, spleen channel; Function regulating qi and activating blood, analgesic therapy, chases after poison.Cure mainly coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.

Herba Patriniae: acrid in the mouth, hardship, cool in nature.Enter stomach, large intestine, Liver Channel.Function cures mainly: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, blood circulation promoting competent silt.For acute appendicitis, lung abscess and sore and toxic, the stagnant caused breast abdomen pain of the excess-heat stasis of blood, the diseases such as the stagnant stomachache of the stasis of blood in puerperal.

Radix Glycyrrhizae: sweet in the mouth, property is put down, GUIXIN, lung, spleen, stomach warp.Can spleen reinforcing stomach function regulating, Yiqi and vein recovery.QI invigorating invigorating middle warmer; Relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; Coordinating the actions of various ingredients in a prescription.Cure mainly asthenia lack of appetite; Leanness yellowish complexion; Shortness of breath and palpitation; Stomachache loose stool; The anxious pain of extremity contraction; Hysteria; Cough and asthma; Laryngopharynx swelling and pain; Carbuncle skin ulcer swells and ache; Infantile carbuncle.

Herba Violae: bitter in the mouth, pungent, cold in nature, GUIXIN, Liver Channel.Can heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.For furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom.Remarks: when Herba Violae is used for hyperactivity of toxic heat, polygamy for oral administration closes Flos Lonicerae, Fructus Forsythiae, Flos Chrysanthemi Indici is equivalent uses; The desirable fresh Herba Violae of external mashes external application carbuncle sore local.

Fructus Forsythiae: bitter in the mouth, cold nature; Return lung, the heart, gallbladder meridian.Effect heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, eliminating carbuncle eliminating stagnation, QI and blood of not only faling apart cohesion again can eliminating carbuncle eliminating stagnation, for clearing away heart-fire, loose part of the body cavity above the diaphragm housing the heart and lungs wind heat.

Radix Scutellariae: bitter in the mouth, cold in nature, return lung, gallbladder, spleen, large intestine, small intestine meridian.Have heat clearing and damp drying, removing heat from blood is antiabortive, detoxicating functions.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.

Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.Can regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.

Radix Paeoniae Rubra: bitter in the mouth, cold nature; Return Liver Channel; Function clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia abdominal mass is gathered, injury from falling down.For maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, lump in the abdomen is suffered from abdominal pain, injury from falling down, carbuncle skin infection.Modern pharmacology research proves, Radix Paeoniae Rubra has antipyretic, antibacterial, spasmolytic, analgesic activity, and humoral and cellular immune response can be suppressed to react, clinical verification shows, radix paeoniae rubrathe for treating acute cholestasis type hepatitis, slow type Serious cholestatic hepatitis of living have obvious pause and transition in rhythm or melody jaundice and choleretic effect.

Flos Carthami: acrid in the mouth, warm in nature.GUIXIN, Liver Channel.Function cures mainly: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.

Herba Taraxaci: sweet in the mouth, micro-hardship, cold in nature, return liver, stomach, kidney channel.Can heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dehumidifying diuresis.Cure mainly the carbuncle pyogenic infections from tumour or sore that all pyretic toxicity are caused, mumps, scrofula; The pharyngalgia that pathogenic heat is caused, conjunctival congestion, gastralgia, dysentery, jaundice, frequent micturition dysurea, cancer of the esophagus cancerous protuberance, worm venom etc.

The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable, can compensate qi and blood, Clearing heat and removing obstruction of fu-organs, regulating QI to relieve pain, thus improving chronic appendicitis symptom, symptom management develops, and strengthens patient's immunity, and energy promoting flow of QI and blood, moisturize relieving restlessness, improve patient's appetite, strengthen the muscle power of patient.

Collect 126 chronic appendicitis patients, man 63 example, female 63 example; Age 18-50 year, average 33 years old; Be divided into matched group (taking levofloxacin tablet) and embodiment group (taking medicament of the present invention) at random, often organize 63 examples; 10 days each courses for the treatment of.

Outcome measure:

Cure: the signs such as Right Lower Abdomen site of disease pain disappear;

Effective: the signs such as Right Lower Abdomen site of disease pain take a turn for the better;

Invalid: the signs such as Right Lower Abdomen site of disease pain are without significant change or increase the weight of.

Statistics is as following table:

Clinical efficacy comparison after table 1 liang group treatment:

Number

Cure

Effectively

Invalid

Effective percentage (cure+effectively)

Treatment group	63	55	7	1	98.4％
						Matched group	63	10	12	41	34.9％

Result: cure 55 examples in 63 routine patients in treatment group, cure rate is 87.3%, cure and effectively account for 62 examples, effective percentage accounts for 98.4%; Cure 10 examples in 63 routine patients in matched group, cure rate is 15.8%, and cure and effectively account for 22 examples, effective percentage accounts for 34.9%; To sum up, the cure rate for the treatment of group and effective percentage are apparently higher than matched group.

Attached several routine case is described further:

Case 1:

Patient Lee, female, 19 years old, tells and has Right Lower Abdomen pain in nearly one week, and pain is just not acute, can tolerate, have the sense of non-standing dull pain.Without diarrhea and vomiting, without melena, without unclean dietary history.Think dyspepsia, after taking XIAOSHI PIAN, pain is without obviously alleviating, and within nearest three days, have low hotness, do not do temperature check, within nearly one day, lower abdominal pain gradually aggravates, then to our hospital, is diagnosed as chronic appendicitis.After taking 1 course for the treatment of of tablet of the present invention, symptom obviously alleviates, and continues to take 1 course for the treatment of, transference cure.

Case 2:

Patient Zhao, man, 32 years old, before 4 days, occurring full abdominal pain without obvious inducement, take Right Lower Abdomen as work, is paroxysmal colic, and the radiation of undirected elsewhere, has nothing to do with position, without heating, fear of cold, without Nausea and vomiting, without hematemesis, diarrhoea.To our hospital, diagnosing chronic appendicitis.By after 2 courses for the treatment of of tablet in treatment of the present invention, recovery from illness is left hospital.

Case 3:

Grandson patient, man, 54 years old.Patient is in being admitted to hospital first 2 days, occur epigastric discomfort without obvious inducement, occur right lower abdomen pain afterwards, body temperature is not high, but without feeling sick and vomiting, without abdominal pain diarrhea and tenesmus, with checking, make a definite diagnosis chronic appendicitis, patient refuses operation, by after 1 course for the treatment of of tablet in treatment of the present invention, symptom alleviates, and fully recovers after continuing to take 2 courses for the treatment of of treatment.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is described in detail, but the present invention is not limited to specific embodiment.

Embodiment 1:

Treat a Chinese medicine formula for chronic appendicitis, formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 5 parts, 15 parts, Semen Persicae, Cortex Moutan 10 parts, Semen Coicis 20 parts, the Radix Paeoniae Alba 8 parts, the Radix Aucklandiae 10 parts, 10 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 15 parts, Radix Angelicae Sinensis 12 parts, 12 parts, Natrii Sulfas, Olibanum 10 parts, Herba Patriniae 30 parts, 5 parts, Radix Glycyrrhizae, Herba Violae 30 parts, Fructus Forsythiae 10 parts, Radix Scutellariae 15 parts, Fructus Aurantii 10 parts, Radix Paeoniae Rubra 15 parts, 10 parts, Flos Carthami, Herba Taraxaci 20 parts.

Embodiment 2:

Treat a Chinese medicine formula for chronic appendicitis, formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 10 parts, 10 parts, Semen Persicae, Cortex Moutan 15 parts, Semen Coicis 10 parts, the Radix Paeoniae Alba 10 parts, the Radix Aucklandiae 8 parts, 15 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 10 parts, Radix Angelicae Sinensis 18 parts, 10 parts, Natrii Sulfas, Olibanum 10 parts, Herba Patriniae 20 parts, 15 parts, Radix Glycyrrhizae, Herba Violae 20 parts, Fructus Forsythiae 15 parts, Radix Scutellariae 10 parts, Fructus Aurantii 15 parts, Radix Paeoniae Rubra 10 parts, 15 parts, Flos Carthami, Herba Taraxaci 10 parts.

Embodiment 3:

Treat a Chinese medicine formula for chronic appendicitis, formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 7 parts, 12 parts, Semen Persicae, Cortex Moutan 12 parts, Semen Coicis 15 parts, the Radix Paeoniae Alba 9 parts, the Radix Aucklandiae 9 parts, 12 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 12 parts, Radix Angelicae Sinensis 15 parts, 12 parts, Natrii Sulfas, Olibanum 12 parts, Herba Patriniae 25 parts, 10 parts, Radix Glycyrrhizae, Herba Violae 25 parts, Fructus Forsythiae 12 parts, Radix Scutellariae 12 parts, Fructus Aurantii 12 parts, Radix Paeoniae Rubra 12 parts, 12 parts, Flos Carthami, Herba Taraxaci 15 parts.

Embodiment 4:

Treat a tableting methods for the Chinese medicine formula of chronic appendicitis, step is as follows:

1) be mixed in proportion by raw medicinal material each in embodiment 1, adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 90%, reflux 2 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 3 times again, reflux 3 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract;

2) by the first step obtain dry cream be placed in super micron mill pulverize 2 hours, after pulverizing and sieving, obtain 300 object micropowders;

3) by the micropowders of second step acquisition, add the starch relative to the microcrystalline Cellulose of its quality 0.1 times, 0.3 times of lactose and 0.2 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.04 times, tablet made by granulate tabletting.

Instructions of taking: every day 3 times, each 2, one after each meal, warm water takes, and within 10 days, is a course for the treatment of.

Embodiment 5:

Treat a tableting methods for the Chinese medicine formula of chronic appendicitis, step is as follows:

1) be mixed in proportion by raw medicinal material each in embodiment 2, adding relative to the determining alcohol of mixture quality 5 times is the ethanol of 85%, reflux 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 1 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract;

2) by the first step obtain dry cream be placed in super micron mill pulverize 3 hours, after pulverizing and sieving, obtain 400 object micropowders;

3) by the micropowders of second step acquisition, add the starch relative to the microcrystalline Cellulose of its quality 0.3 times, 0.15 times of lactose and 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 times, tablet made by granulate tabletting.

Instructions of taking: every day 3 times, each 4, one after each meal, warm water takes, and within 10 days, is a course for the treatment of.

Embodiment 6:

Treat a tableting methods for the Chinese medicine formula of chronic appendicitis, step is as follows:

1) be mixed in proportion by raw medicinal material each in embodiment 3, adding relative to the determining alcohol of mixture quality 4.5 times is the ethanol of 90%, reflux 3 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2.5 times again, reflux 2 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract;

2) by the first step obtain dry cream be placed in super micron mill pulverize 1.5 hours, after pulverizing and sieving, obtain 350 object micropowders;

3) by the micropowders of second step acquisition, add the starch relative to the microcrystalline Cellulose of its quality 0.2 times, 0.22 times of lactose and 0.28 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.032 times, tablet made by granulate tabletting.

Instructions of taking: every day 3 times, each 3, one after each meal, warm water takes, and within 10 days, is a course for the treatment of.

Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.

Claims (3)

1. treat a Chinese medicine formula for chronic appendicitis, it is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 5-10 part, Semen Persicae 10-15 part, Cortex Moutan 10-15 part, Semen Coicis 10-20 part, Radix Paeoniae Alba 8-10 part, Radix Aucklandiae 8-10 part, Radix Rehmanniae 10-15 part, Radix Salviae Miltiorrhizae 10-15 part, Radix Angelicae Sinensis 12-18 part, Natrii Sulfas 10-15 part, Olibanum 10-15 part, Herba Patriniae 20-30 part, Radix Glycyrrhizae 5-15 part, Herba Violae 20-30 part, Fructus Forsythiae 10-15 part, Radix Scutellariae 10-15 part, Fructus Aurantii 10-15 part, Radix Paeoniae Rubra 10-15 part, Flos Carthami 10-15 part, Herba Taraxaci 10-20 part.

2. a kind of Chinese medicine formula for the treatment of chronic appendicitis according to claim 1, is characterized in that being formed by the Chinese medicine proportioning of following parts by weight: Radix Et Rhizoma Rhei 7 parts, 12 parts, Semen Persicae, Cortex Moutan 12 parts, Semen Coicis 15 parts, the Radix Paeoniae Alba 9 parts, the Radix Aucklandiae 9 parts, 12 parts, the Radix Rehmanniae, Radix Salviae Miltiorrhizae 12 parts, Radix Angelicae Sinensis 15 parts, 12 parts, Natrii Sulfas, Olibanum 12 parts, Herba Patriniae 25 parts, 10 parts, Radix Glycyrrhizae, Herba Violae 25 parts, Fructus Forsythiae 12 parts, Radix Scutellariae 12 parts, Fructus Aurantii 12 parts, Radix Paeoniae Rubra 12 parts, 12 parts, Flos Carthami, Herba Taraxaci 15 parts.

3. a tableting methods for the Chinese medicine formula for the treatment of chronic appendicitis according to claim 1, is characterized in that step is as follows:

1) be mixed in proportion by each for above-mentioned Chinese medicine raw medicinal material, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract;

2) by the first step obtain dry cream be placed in super micron mill pulverize 2 ~ 3 hours, after pulverizing and sieving, obtain 300 ~ 400 object micropowders;

3) by the micropowders of second step acquisition, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, tablet made by granulate tabletting.