CN103520681A - Traditional Chinese medicine for treating spleen-and-kidney deficiency type chronic colitis - Google Patents
Traditional Chinese medicine for treating spleen-and-kidney deficiency type chronic colitis Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating spleen-and-kidney deficiency type chronic colitis. The problem of medicine application of treating spleen-and-kidney deficiency type chronic colitis can be effectively solved. The technical scheme is as follows: the traditional Chinese medicine comprises the following components in parts by weight: 12-18g of dangshen roots, 27-33g of fried astragalus membranaceus, 12-18g of poria cocos, 9-15g of bighead atractylodes rhizome, 12-18g of semen psoraleae, 4-8g of schisandra chinensis, 4-8g of semen myristicae, 2-4g of fructus evodiae, 12-18g of longan aril, 27-33g of Chinese yam, 17-23g of common bletilla tuber, 27-33g of parslane herbs, 6-12g of fructus amomi, 9-15g of dried tangerine peel, 4-8g of dried ginger and 4-8g of honey-fried licorice root. The traditional Chinese medicine has the functions of tonifying the spleen and kidney, solidifying the intestines and curing the diarrhea, warming the middle qi and tonifying the instability, and regulating the qi and conducting the channels, and is effectively used for treating the spleen-and-kidney deficiency type chronic colitis and has good curative effect; the medicine is safely and orally taken; therefore, the traditional Chinese medicine is the creative medicine for treating the spleen-and-kidney deficiency type chronic colitis.
Description
Technical field
The present invention relates to medicine, particularly a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis.
Background technology
Chronic colitis is still rectum and colon chronic nonspecific inflammation disease not fully aware of of a kind of cause of disease, and pathological changes is mainly limited to colorectal mucosa and Submucosa, and clinical manifestation is diarrhoea, mucus bloody purulent stool, stomachache.State of an illness weight not etc., is not the chronic course of disease of outbreak repeatedly more.Primary disease treatment difficulty is large, and exists certain ，Bei World Health Organization (WHO) that is related to classify one of modern difficult treatment as with the morbidity of colon cancer.
Modern medicine it be unclear that its etiology and pathology pathogenesis system, and research relatively lags behind, and cause clinical treatment slow curative effect and lack specificity, to the therapeutic purposes of colitis, be induction and maintainable remission at present, Therapeutic Principle controls symptom as early as possible for active stage; Catabasis maintains treatment, control recurrence; Prevent and treat complication, if desired operation in time.
The integrative therapy means of colitis are various at present, have drug oral (dosage form has decoct, pill, pellet, tablet etc.), plug anus, coloclysis, acupuncture and additive method as hydrotherapy, abdomen bag, air-flow disperse, recombination energy, stem cell transplantation etc.Clinical treatment still lacks satisfied Therapeutic Method, and the medicine that western medicine is conventional has aminosalicylic acids medicine, corticosteroid, immunomodulator, antibiotic etc.Base acid salicylic acid is the first-line drug for the treatment of UC, but a few patients may occur headache, feels sick, stomachache, erythra, dizziness and arthralgia, the untoward reaction such as hepatorenal damage.Adrenocortical hormone is still the treatment classical medicine of UC active stage, be also serious symptom UC choice drug normal with aminosalicylic acids drug combination, but this class medicine has danger and the rebound phenomenon of bringing out or increasing the weight of infection.Chinese medicine report is more, have that heat-clearing and toxic substances removing, heat clearing and damp drying, regulating QI row are wet, expelling wind and dampness, regulating QI to relieve pain, invigorating the spleen and benefiting QI, spleen invigorating suppressing the hyperactive liver, reinforcing spleen and kidney, removing the necrotic tissue and promoting granulation, blood circulation promoting and blood stasis dispelling, detoxification and removing stasis, astringing to arrest bleeding, removing heat from blood and promoting blood circulation, warming YANG and invigorating QI etc., be summed up and how from spleen, liver, kidney opinion, control, from wet, heat, void, the opinion of becoming silted up, control, but clinical efficacy is not etc., and therapeutic effect is not good.Therefore, the improvement for the treatment of yang deficiency of spleen and stomache chronic colitis medicine is the problem of needing at present solution badly.
Summary of the invention
For above-mentioned situation, for solving the defect of prior art, the present invention's object is just to provide a kind of Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis, can effectively solve the medication problem for the treatment of yang deficiency of spleen and stomache chronic colitis.
The technical scheme that the present invention solves is, this Chinese medicine is by following weighing scale: Radix Codonopsis 12-18g, Radix Astragali Preparata 27-33g, Poria 12-18g, Rhizoma Atractylodis Macrocephalae 9-15g, Fructus Psoraleae 12-18g, Fructus Schisandrae Chinensis 4-8g, Semen Myristicae 4-8g, Zhu's Wu cornel 2-4g, Arillus Longan 12-18g, Rhizoma Dioscoreae 27-33, Pseudobulbus Bletillae (Rhizoma Bletillae) 17-23g, Herba Portulacae 27-33g, Fructus Amomi 6-12g, Pericarpium Citri Reticulatae 9-15g, Rhizoma Zingiberis 4-8g and Radix Glycyrrhizae Preparata 4-8g form.
Chinese medicine of the present invention is granule or oral liquid, or makes according to a conventional method a kind of of tablet, decoction, powder, pill, powder.
The present invention has that warming and recuperating the spleen and kidney, intestine-stabling and anti-diarrheal, warming middle-JIAO residence are puckery, the effect of regulating QI intestinal stasis relieving, is effective to treat yang deficiency of spleen and stomache chronic colitis, good effect, and drug safety, is the innovation on treatment yang deficiency of spleen and stomache chronic colitis medicine.
The specific embodiment
Below in conjunction with embodiment, the specific embodiment of the present invention is described in further detail.
Embodiment 1
This Chinese medicine is by following weighing scale: Radix Codonopsis 12g, Radix Astragali Preparata 27g, Poria 12g, Rhizoma Atractylodis Macrocephalae 9g, Fructus Psoraleae 12g, Fructus Schisandrae Chinensis 4g, Semen Myristicae 4g, Zhu's Wu cornel 2g, Arillus Longan 12g, Rhizoma Dioscoreae 27, Pseudobulbus Bletillae (Rhizoma Bletillae) 17g, Herba Portulacae 27g, Fructus Amomi 6g, Pericarpium Citri Reticulatae 9g, Rhizoma Zingiberis 4g and Radix Glycyrrhizae Preparata 4g form.
Embodiment 2
This Chinese medicine is by following weighing scale: Radix Codonopsis 15g, Radix Astragali Preparata 30g, Poria 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Psoraleae 15g, Fructus Schisandrae Chinensis 6g, Semen Myristicae 6g, Zhu's Wu cornel 3g, Arillus Longan 15g, Rhizoma Dioscoreae 30, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Herba Portulacae 30g, Fructus Amomi 9g, Pericarpium Citri Reticulatae 12g, Rhizoma Zingiberis 6g and Radix Glycyrrhizae Preparata 6g form.
Embodiment 3
This Chinese medicine is by following weighing scale: Radix Codonopsis 18g, Radix Astragali Preparata 33g, Poria 18g, Rhizoma Atractylodis Macrocephalae 15g, Fructus Psoraleae 18g, Fructus Schisandrae Chinensis 8g, Semen Myristicae 8g, Zhu's Wu cornel 4g, Arillus Longan 18g, Rhizoma Dioscoreae 33, Pseudobulbus Bletillae (Rhizoma Bletillae) 23g, Herba Portulacae 33g, Fructus Amomi 12g, Pericarpium Citri Reticulatae 15g, Rhizoma Zingiberis 8g and Radix Glycyrrhizae Preparata 8g form.
Embodiment 4
This Chinese medicine is by following weighing scale: Radix Codonopsis 12-15g, Radix Astragali Preparata 27-30g, Poria 12-15g, Rhizoma Atractylodis Macrocephalae 9-12g, Fructus Psoraleae 12-15g, Fructus Schisandrae Chinensis 4-6g, Semen Myristicae 4-6g, Zhu's Wu cornel 2-2.5g, Arillus Longan 12-15g, Rhizoma Dioscoreae 27-30, Pseudobulbus Bletillae (Rhizoma Bletillae) 17-20g, Herba Portulacae 27-30g, Fructus Amomi 6-9g, Pericarpium Citri Reticulatae 9-12g, Rhizoma Zingiberis 4-6g and Radix Glycyrrhizae Preparata 4-6g form.
Embodiment 5
This Chinese medicine is by following weighing scale: Radix Codonopsis 16-18g, Radix Astragali Preparata 31-33g, Poria 16-18g, Rhizoma Atractylodis Macrocephalae 13-15g, Fructus Psoraleae 16-18g, Fructus Schisandrae Chinensis 7-8g, Semen Myristicae 7-8g, Zhu's Wu cornel 3-4g, Arillus Longan 16-18g, Rhizoma Dioscoreae 31-33, Pseudobulbus Bletillae (Rhizoma Bletillae) 21-23g, Herba Portulacae 31-33g, Fructus Amomi 10-12g, Pericarpium Citri Reticulatae 13-15g, Rhizoma Zingiberis 7-8g and Radix Glycyrrhizae Preparata 7-8g form.
Chronic colitis yang deficiency of spleen and stomache be clinical in one of the most common pattern of syndrome, mostly be the course of disease more of a specified duration, acute attack occurs with alleviating alternately, the course of disease is longer, outbreak repeatedly, clinical mainly take borborygmus diarrhoea, peace, coldness of the body with chills are feature after rushing down.Because its Clinical symptoms is resembling of one deficiency and coldness, treatment should be with " dry spleen, the kidney warming, acid receipts, astringent or styptic treatment for spontaneous sweating, ascending " five methods for controlling.At weakness of the spleen and stomach especially deficiency of spleen-YANG and kidneyYANG stage, disease be take in healthy energy thanks to as main, often few evil in stagnant, or naivete is without stagnant, patient's condition take that this loses intestinal cunning as main, in righting, must reverse patient's condition, make it to turn puckery by logical, in medication, should puckeryly should not lead to, moderately apply the medicine of relieving diarrhea with astringents.
The present invention is in conjunction with clinical treatment experience, according to (chronic colitis) etiology and pathogenesis of having loose bowels, the features such as clinical manifestation have been done, and the present invention closes the evolution of SISHEN WAN plus-minus by decoction of four noble drugs and forms, stress warming and recuperating the spleen and kidney and antidiarrheal, warming and recuperating the spleen and kidney, relieving diarrhea with astringents, in component of the present invention, wherein, Fructus Psoraleae of the present invention, Fructus Evodiae, Semen Myristicae, Fructus Schisandrae Chinensis are got the meaning of SISHEN WAN, and the kidney warming warms up spleen, relieving diarrhea with astringents; Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae replenishing QI to invigorate the spleen, the gas strengthening the spleen and stomach, taste are healthy and vigorous, coordinate with Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis, the Fructus Evodiae of the warm the intestines and stomach of warming middle-JIAO, and activating the spleen soil, rouses oneself middle-jiao yang, function of the spleen and stomach, and middle-jiao yang, function of the spleen and stomach is shaken multiple, rises shipping and turns, and can make to rise clearly turbid falling, and it is normal that gastrointestinal function recovers; Pericarpium Citri Reticulatae, the appetizing of Fructus Amomi regulating qi-flowing for strengthening spleen; Radix Astragali Preparata invigorating middle warmer, beneficial vigour, warm three warmers, shape taste, real space between skin and muscles, granulation promoting evacuation of pus, controls internal injury overstrain, and diarrhea due to hypofunction of the spleen is excellent.Arillus Longan sweet in the mouth temperature, property peace, heart-spleen boosting, fills blood, strengthening the spleen and stomach, moistening five ZANG-organs, tonifying YANG QI invigorating, kind deficiency of vital energy edema, the diarrhea due to hypofunction of the spleen controlled.Pseudobulbus Bletillae (Rhizoma Bletillae) hardship is sweet, cool, enter lung meridian, has the merit of tonifying the lung, hemostasis, detumescence, granulation promoting, sore, cures mainly carbuncle malignant boil and loses cellulitis, ulcer pain, hemorrhoidal hamorrhage dysentery.External has absorption and discharges secretions, and the protection function of recovery and enhancing body, produces protecting film, and control and protect from infection, clean wound, promotion granulation tissue is newborn, accelerates the effects such as ulcer healing.Herba Portulacae (also name longevity greens/mustard green) eliminating damp-heat, loose blood detumescence, controls hematodiarrhoea pus and blood, carbuncle malignant boil.This product contains abundant vitamin A sample material, thus can promote that epithelial physiological function is tending towards normally, and can promote the healing of ulcer.Herba Portulacae is for escherichia coli, and the effect of all drawing up of dysentery bacterium, Bacillus typhi, pathogenic dermatophytes, has obvious contraction to blood vessel, and can promote Intestinal motility.Medicine-feeding is share, and has invigorating QI and blood, and the kidney warming warms up spleen, convergence ulcer, the merit of intestine-stabling and anti-diarrheal.Spleen kidney two is mended, and warming middle-JIAO residence is puckery, regulating QI intestinal stasis relieving, and the damp and hot poison in energy Qinghua of holding concurrently is evil, and gastrointestinal function is coordinated, and ulcerative colitis is from rehabilitation gradually.
Above-mentioned component science, reasonable compatibility, support mutually, has that warming and recuperating the spleen and kidney, intestine-stabling and anti-diarrheal, warming middle-JIAO residence are puckery, the effect of regulating QI intestinal stasis relieving, be effective to treat yang deficiency of spleen and stomache chronic colitis, good effect, drug safety, and obtained fully proving through clinical data, relevant clinical data is as follows:
(1), the inclusion criteria of yang deficiency of spleen and stomache chronic colitis:
According to clinical symptoms, press the diagnostic criteria of yang deficiency of spleen and stomache chronic colitis, select typical yang deficiency of spleen and stomache patients with chronic colitis 120 examples, male 64 examples wherein, female's 56 examples, the age is (60.1 ± 11.5) year.
(2), the diagnostic criteria of yang deficiency of spleen and stomache chronic colitis:
1, diarrhoea: Mucous Stool and bloody purulent stool, the lighter every day 3-4 times, tens of times of severe one or diarrhoea and alternately appearance of constipation.
2, stomachache: slight patient is without stomachache or only have abdominal discomfort.Generally having slightly and suffer from abdominal pain to moderate, is left lower quadrant or lower abdomen paroxysmal pain, relates to the rule that full abdomen has pain one awareness of defecation one to alleviate after an action of the bowels.
3, constipation: once, feces is as sheep dung sample for constipation defecation on the 4-5th, and very not eating cathartic can not relieving constipation.
4, other symptoms: abdominal distention, become thin, weak, borborygmus, insomnia, dreaminess, the disease such as be afraid of cold.
(3), efficacy assessment standard:
cure: clinical symptom disappearance, inspection recover normal;
effective: clinical symptoms obviously alleviates, checks obviously and changes;
take a turn for the better: clinical symptom relief, inspection slightly improve;
invalid:clinical symptoms sign is not improved.
(4), therapeutic scheme
by Chinese medicine granulation of the present invention agent, 1 bag, for 10g, each serving 1 bag, takes 3 times on the 1st; Or making oral liquid, every 20 ml, take 1 for 1 time, within 1st, take 3 times; It within 15 days, is a course for the treatment of.
(5), statistical procedures:
By above-mentioned (four) therapeutic scheme, the Chinese medicine that oral the present invention provides, added up after 6 courses for the treatment of, this invention treatment by Chinese herbs yang deficiency of spleen and stomache chronic colitis curative effect of clinical use is better, by the clinical observation to 120 routine yang deficiency of spleen and stomache patients with chronic colitis, cure 90 examples, effective 14 examples, 10 examples take a turn for the better, cure rate reaches 75%, and total effective rate is up to 95%, evident in efficacy, through Long-term clinical checking, have no adverse reaction.
(6), conclusion
Compatibility of the present invention is reasonable, evident in efficacy, and spleen kidney two is mended, warming middle-JIAO residence is puckery, regulating QI intestinal stasis relieving, the damp and hot poison in energy Qinghua of holding concurrently is evil, and gastrointestinal function is coordinated, it is the active drug that is used for the treatment of yang deficiency of spleen and stomache chronic colitis, effective percentage reaches 95%, has no side effect, and stable curative effect, safe and reliable, there is actual clinical meaning.
Claims (7)
1. a Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 12-18g, Radix Astragali Preparata 27-33g, Poria 12-18g, Rhizoma Atractylodis Macrocephalae 9-15g, Fructus Psoraleae 12-18g, Fructus Schisandrae Chinensis 4-8g, Semen Myristicae 4-8g, Zhu's Wu cornel 2-4g, Arillus Longan 12-18g, Rhizoma Dioscoreae 27-33, Pseudobulbus Bletillae (Rhizoma Bletillae) 17-23g, Herba Portulacae 27-33g, Fructus Amomi 6-12g, Pericarpium Citri Reticulatae 9-15g, Rhizoma Zingiberis 4-8g and Radix Glycyrrhizae Preparata 4-8g form.
2. the Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis according to claim 1, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 12g, Radix Astragali Preparata 27g, Poria 12g, Rhizoma Atractylodis Macrocephalae 9g, Fructus Psoraleae 12g, Fructus Schisandrae Chinensis 4g, Semen Myristicae 4g, Zhu's Wu cornel 2g, Arillus Longan 12g, Rhizoma Dioscoreae 27, Pseudobulbus Bletillae (Rhizoma Bletillae) 17g, Herba Portulacae 27g, Fructus Amomi 6g, Pericarpium Citri Reticulatae 9g, Rhizoma Zingiberis 4g and Radix Glycyrrhizae Preparata 4g form.
3. the Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis according to claim 1, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 15g, Radix Astragali Preparata 30g, Poria 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Psoraleae 15g, Fructus Schisandrae Chinensis 6g, Semen Myristicae 6g, Zhu's Wu cornel 3g, Arillus Longan 15g, Rhizoma Dioscoreae 30, Pseudobulbus Bletillae (Rhizoma Bletillae) 20g, Herba Portulacae 30g, Fructus Amomi 9g, Pericarpium Citri Reticulatae 12g, Rhizoma Zingiberis 6g and Radix Glycyrrhizae Preparata 6g form.
4. the Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis according to claim 1, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 18g, Radix Astragali Preparata 33g, Poria 18g, Rhizoma Atractylodis Macrocephalae 15g, Fructus Psoraleae 18g, Fructus Schisandrae Chinensis 8g, Semen Myristicae 8g, Zhu's Wu cornel 4g, Arillus Longan 18g, Rhizoma Dioscoreae 33, Pseudobulbus Bletillae (Rhizoma Bletillae) 23g, Herba Portulacae 33g, Fructus Amomi 12g, Pericarpium Citri Reticulatae 15g, Rhizoma Zingiberis 8g and Radix Glycyrrhizae Preparata 8g form.
5. the Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis according to claim 1, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 12-15g, Radix Astragali Preparata 27-30g, Poria 12-15g, Rhizoma Atractylodis Macrocephalae 9-12g, Fructus Psoraleae 12-15g, Fructus Schisandrae Chinensis 4-6g, Semen Myristicae 4-6g, Zhu's Wu cornel 2-2.5g, Arillus Longan 12-15g, Rhizoma Dioscoreae 27-30, Pseudobulbus Bletillae (Rhizoma Bletillae) 17-20g, Herba Portulacae 27-30g, Fructus Amomi 6-9g, Pericarpium Citri Reticulatae 9-12g, Rhizoma Zingiberis 4-6g and Radix Glycyrrhizae Preparata 4-6g form.
6. the Chinese medicine for the treatment of yang deficiency of spleen and stomache chronic colitis according to claim 1, it is characterized in that, this Chinese medicine is by following weighing scale: Radix Codonopsis 16-18g, Radix Astragali Preparata 31-33g, Poria 16-18g, Rhizoma Atractylodis Macrocephalae 13-15g, Fructus Psoraleae 16-18g, Fructus Schisandrae Chinensis 7-8g, Semen Myristicae 7-8g, Zhu's Wu cornel 3-4g, Arillus Longan 16-18g, Rhizoma Dioscoreae 31-33, Pseudobulbus Bletillae (Rhizoma Bletillae) 21-23g, Herba Portulacae 31-33g, Fructus Amomi 10-12g, Pericarpium Citri Reticulatae 13-15g, Rhizoma Zingiberis 7-8g and Radix Glycyrrhizae Preparata 7-8g form.
7. the Chinese medicine of the treatment yang deficiency of spleen and stomache chronic colitis described in claim 1 or 2-6 any one, is characterized in that, this Chinese medicine is granule or oral liquid, or makes according to a conventional method a kind of of tablet, decoction, powder, pill, powder.
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| CN104352712A (en) * | 2014-10-17 | 2015-02-18 | 王刚 | Traditional Chinese medicine composition for treating chronic colitis |
| CN104367926A (en) * | 2014-11-20 | 2015-02-25 | 青岛恒波仪器有限公司 | Traditional Chinese medicine preparation for treating predawn diarrhea and preparation method thereof |
| CN105031570A (en) * | 2015-07-04 | 2015-11-11 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea |
| CN105169328A (en) * | 2015-09-30 | 2015-12-23 | 王鹏飞 | Traditional Chinese medicine preparation for treating chronic colitis |
| CN107582913A (en) * | 2017-10-25 | 2018-01-16 | 周安德 | A kind of Chinese medicine for treating chronic colitis |
| CN108404033A (en) * | 2018-05-17 | 2018-08-17 | 杜建伟 | A kind of Chinese medicine of tcm internal medicine treatment enteritis |
| EP4125983A4 (en) * | 2020-04-03 | 2024-02-14 | Medihelpline Co Ltd | An oral pharmaceutical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of inflammatory disease and the use thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104352712A (en) * | 2014-10-17 | 2015-02-18 | 王刚 | Traditional Chinese medicine composition for treating chronic colitis |
| CN104367926A (en) * | 2014-11-20 | 2015-02-25 | 青岛恒波仪器有限公司 | Traditional Chinese medicine preparation for treating predawn diarrhea and preparation method thereof |
| CN105031570A (en) * | 2015-07-04 | 2015-11-11 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea |
| CN105169328A (en) * | 2015-09-30 | 2015-12-23 | 王鹏飞 | Traditional Chinese medicine preparation for treating chronic colitis |
| CN107582913A (en) * | 2017-10-25 | 2018-01-16 | 周安德 | A kind of Chinese medicine for treating chronic colitis |
| CN108404033A (en) * | 2018-05-17 | 2018-08-17 | 杜建伟 | A kind of Chinese medicine of tcm internal medicine treatment enteritis |
| EP4125983A4 (en) * | 2020-04-03 | 2024-02-14 | Medihelpline Co Ltd | An oral pharmaceutical composition comprising an extract of combined herbs comprising longanae arillus for the treatment or alleviation of inflammatory disease and the use thereof |
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| CN103520681B (en) | 2016-01-20 |
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