CN105031570A - Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea - Google Patents
Traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicine, and more specifically relates to a traditional Chinese medicine preparation used for treating infant spleen-kidney-yang deficiency diarrhea. The traditional Chinese medicine preparation is prepared from salt-processed psoralea corylifolia, baked semen myristicae, rhizoma atractylodis macrocephalae, dried ginger, bark of common Jujube, herb of biternate beggarticks, radix aucklandiae, and juncus effusus. The traditional Chinese medicine preparation is prepared based on a theory of traditional Chinese medicine that internal illness is treated via external treatment; medicinal materials are selected carefully; compatibility of medicines is strict; mutual promotion of the medicinal materials is achieved. The characteristics of children are taken into consideration fully; external compress is adopted as a first choice; a treatment method is simple and practical; and effects are excellent.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of children's's yang deficiency of spleen and stomache diarrhoea.
Background technology
Diarrhoea is one of modal disease of children's, and especially more common with the infant of less than 2 years old, the age is less, and sickness rate is higher.Clinical manifestation mainly contains times of defecation and increases, and excrement matter is thin or as water sample etc.Children's period, the morphological development of each organ of body and physiological function are all immature and incomplete, and body is tender, and QI and blood is foot, weakness of spleen and stomach, and kidney qi is not filled, and easy being invaded by exogenous pathogen or internal injury humidity hysteresis cause transformation and transportation of the spleen and stomach lack of proper care and suffer from diarrhoea
Infantile diarrhea belongs to the traditional Chinese medical science and " to have loose bowels " category."Nei Jing" cloud: " not becoming to rush down without wet ", Zhang Jingyue was once said: " basis of having loose bowels is invariably due to taste ", because of " the kidney usually involved in chronic disease ", spleen and kidney belong to the relation of nature and nurture on physiology, the normal transporting of spleen depends on the warm promotion of kidney yang, and on pathology, diarrhea due to hypofunction of the spleen with the passing of time, easily cause the virtual loss of kidney yang, and insufficiency of kidney-YANG, then can not warm spleen sun, help its digesting food, can not prohibit being fixed in down, make to have loose bowels and increase the weight of, so-called " the not warm soil of fire ", " close and hide dereliction of duty ".Therefore yang deficiency of spleen and stomache diarrhoea clinical condition is shown in: incessant chronic diarrhea, eat and namely rush down, excrement matter is rare clearly, aqueous-grainy diarrhea, or diarrhea before dawn, defecation dysentery is not well, excrement matter in vain glutinous wetting is frozen, abdominal swelling, spiritlessness and weakness, or see proctoptosis, coldness of the body with chills, complexion HUANGBAI(sic), indigestion and loss of appetite lack of appetite, lethargy, sleeping with eyes half-closed when sleeping, pale tongue, tongue is white.Chinese traditional treatment infantile diarrhea is according to feces character and Symptoms, differentiates cold and heat, examines deficiency and excess and carries out typing opinion and control.
The body constitution of children's is general more weak, and Western medicine improper use easily causes children's's comparatively significantly untoward reaction, thus impacts for the health of children's.In addition, not easily submit to restraint because children's also has, current medicine is difficult to be suitable for child.
Motherland's medical science is thought, umbilicus is the place of " SHENQUE acupoint ", the logical vital organs of the human body, and the interior even twelve regular channels and eight extra-channel are total pivots of yin-Yang gasification.From fetal development and modern anatomic angle, umbilicus is embryo development procedure midfield parietal vessel closed place the latest, and subcutaneous fat is less and be distributed with abundant vasoganglion, lymph circulation net and nerve, high to the sensitivity of medicine, barrier action is little, is conducive to drug absorption.Percutaneous dosing is a kind of ancient and traditional administering mode in China.Navel therapy selects suitable medicine to make powder, paste, medicine cake etc., utilize the Absorption of umbilical part local skin and the stimulation at acupuncture point, first pass effect and the gastrointestinal of having skipped liver destroy, the efficacy of a drug is gone directly disease institute, also make the property of medicine by fur space between skin and muscles going from the exterior into the interior, follow meridians and reach internal organs, to regulate negative and positive of qi and blood, strengthening vital QI to eliminate pathogenic factors, thus cure diseases.
Summary of the invention
Inventor is according to the theory of Chinese medical science of " reason of external treatment and the reason for the treatment of by oral administration of medicines; the method for external treatment and the method for the treatment of by oral administration of medicines ", consult the invaluable experience of motherland's medical science Coryza Treated by Syndrome Differentiation, consider the property feature of prescription medicine simultaneously, weed out the old and bring forth the new, provide a kind of Chinese medicine preparation for the treatment of children's's yang deficiency of spleen and stomache diarrhoea, this Chinese medicine preparation has good effect for children's's yang deficiency of spleen and stomache diarrhoea, cure rate is high, has no side effect.
For achieving the above object, the technical solution used in the present invention is as follows:
Treat a Chinese medicine preparation for children's's yang deficiency of spleen and stomache diarrhoea, it is characterized in that it is that medicinal raw material is according to certain weight elaborate by stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis, Cortex Jujubae, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), the Radix Aucklandiae, Medulla Junci.
The weight of medicinal raw material of the present invention gropes to sum up to draw through inventor in a large number, and each medicinal raw material Chinese medicine preparation of the present invention within the scope of following weight parts all has good curative effect: stir-baked SEMEN PSORALEAE with salt solution 5-9 part, Semen Myristicae 4-8 part, Rhizoma Atractylodis Macrocephalae 3-7 part, Rhizoma Zingiberis 2-4 part, Cortex Jujubae 5-8 part, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 7-10 part, Radix Aucklandiae 2-4 part, Medulla Junci 4-7 part.
Side's solution of the present invention is: stir-baked SEMEN PSORALEAE with salt solution warming the kidney to activate YANG, warming spleen and stopping diarrha; Semen Myristicae warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents; Two medicines share, reinforce spleen and kidney together, have effect of warming the kidney to activate YANG, invigorating the spleen to arrest diarrhea, are monarch drug.Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, dampness diuretic; Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, altogether principal drug assistance warming middle-JIAO and strengthening the spleen, and dampness diuretic antidiarrheal is ministerial drug.Cortex Jujubae relieving diarrhea with astringents, principal drug assistance antidiarrheal; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) is cool in nature, and kind heat-clearing and toxic substances removing, antidiarrheal, in order to the above-mentioned pungent using warming therapy product of using corrigent, make using warming therapy unlikely dry, tool is adjuvant drug.Medulla Junci is sweet light cold, and abnormal smells from the patient is all light, and the lighter floats, and specially enters cardiopulmonary; Nature and flavor are all light, light master in oozing, from upper along under, regulating fluid apssage, treating diarrhea by diuretics; Radix Aucklandiae promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, to get puckery and not stay the meaning of heresy, tool is for making medicine.We's warming middle-JIAO has benefit, has row in puckery, and disease can surely middle convalesce.
Preferably, treat a Chinese medicine preparation for children's's yang deficiency of spleen and stomache diarrhoea, it is characterized in that it is made up of the medicinal raw material of following weight portion: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Rhizoma Zingiberis 2.5 parts, Cortex Jujubae 6 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 3 parts, Medulla Junci 5 parts.
The another program optimized is: a kind of Chinese medicine preparation for the treatment of children's's yang deficiency of spleen and stomache diarrhoea, is characterized in that it is made up of the medicinal raw material of following weight portion: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 6 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Rhizoma Zingiberis 2 parts, Cortex Jujubae 8 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 2.5 parts, Medulla Junci 6 parts.
The raw materials used present Research of the present invention is as described below.
Fructus Psoraleae: pungent, bitter, temperature.Return kidney, spleen channel.Function cures mainly: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea.The present invention uses stir-baked SEMEN PSORALEAE with salt solution to warm up spleen anti-diarrhea effect to strengthen the kidney warming.
Semen Myristicae: pungent, temperature.Return spleen, stomach, large intestine channel.Function cures mainly: warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents.For Deficiency and coldness of spleen and stomach, incessant chronic diarrhea, abdominal distention, lack of appetite is vomitted.
The Rhizoma Atractylodis Macrocephalae: bitter, sweet, temperature.Return spleen, stomach warp.Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and hidroschesis is antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Rhizoma Zingiberis: pungent, hot.Return spleen, stomach, kidney, the heart, lung meridian.Function cures mainly: warming spleen and stomach for dispelling cold, and recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
Cortex Jujubae: be the bark of Rhamnaceae plant Fructus Jujubae, the whole year all can be received and be adopted, spring is best, uses crescent reaping hook, is scraped by Lao Pi, dry from jujube tree trunk.Warm in nature, nontoxic.Return lung; Large intestine channel.Function cures mainly: astringing to arrest diarrhea, eliminates the phlegm, antitussive, antiinflammatory, hemostasis.Control dysentery, enteritis, chronic tracheitis, blurred vision is failed to understand, burn and scald, traumatic hemorrhage.
Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae): sweet in the mouth; Micro-hardship; Cool in nature.Function cures mainly: heat-clearing and toxic substances removing; Cooling blood for hemostasis.Main cold, fever; Jaundice; Have loose bowels; Dysentery; Heat in blood is spitted blood; Metrorrhagia; Traumatic injury; Carbuncle sore tumefacting virus; The arthroncus of knee; Mange.
The Radix Aucklandiae: pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Function cures mainly: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.For breast gastral cavity distending pain, heavy after dysentery, food stagnation does not disappear, anorexia.The real intestinal antidiarrheal of Radix Aucklandiae (roasted).For stomachache of having loose bowels.
Medulla Junci: sweet, light, is slightly cold.GUIXIN, lung, small intestine meridian.Function cures mainly: clearing away heart-fire, diuresis.For vexed insomnia, the puckery pain of oliguria, aphtha of the mouth and tongue.
Chinese medicine preparation of the present invention is active component by stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis, Cortex Jujubae, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), the Radix Aucklandiae, Medulla Junci or its water and/or its extractive with organic solvent or volatile oil, adds pharmaceutically acceptable adjuvant or complementary composition is prepared into pharmaceutically conventional dosage form.
Preferably, dosage form conventional on pharmaceutics described above is exterior-applied formulation,
Preferably above-mentioned exterior-applied formulation is powder.
Usage and dosage: get Chinese powder medicine 1.0 ~ 1.5g of the present invention, does wet suitable pasty state with rice vinegar furnishing, is laid in the annulus of sky plaster, is affixed on SHENQUE acupoint; Or be placed in the suitable non-woven fabrics of size, spread on SHENQUE acupoint, surrounding medical adhesive tape is fixed.
Present invention also offers a kind of preparation method of the Chinese powder medicine for infantile spleen deficiency type diarrhoea, it comprises the steps: ethanol extraction secondary stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis being added 50%, each 1.5-2.0 hour, collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci are decocted with water secondary, first time add water into medical material weight portion 5-8 doubly, decoct 1.5-2.0 hour, second time adds water as the 3-4 of medical material weight portion doubly decocts 1.0-1.5 hour, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add appropriate sodium carboxymethyl cellulose, mix homogeneously, obtain powder of the present invention.
By animal toxicity test and clinical observation test, set forth the beneficial effect of Chinese medicine preparation of the present invention further.
The skin irritation test of New Zealand white rabbit: be divided into normal skin group and skin injury group, adopts consubstantiality left and right sides self-contrast method, and duration of test two groups of rabbit spirit, sign are good, and appetite activity is normal; Without dead, also have no any untoward reaction; Hematological examination, biochemical investigation are showed no exception; System becomes celestial and each internal organs histopathology no abnormality seen; Restorative observation has no retardance toxic reaction, the Testing index normal value of reference people and rabbit, above result is all within normal range, and two groups of more equal nonsignificances (P>0.05), show that rabbit does not produce toxic reaction with powder of the present invention for a long time.
The skin allergy experiment of Cavia porcellus: test arranges the powder group of the embodiment of the present invention 2, tablet vinegar matched group and 2,4-dinitrochlorobenzene positive controls, result shows: experimental result display positive controls erythema and edema are all clearly, the powder group of tablet vinegar matched group and the embodiment of the present invention 2 then skin smooth, without erythema, without edema, do not show any anaphylaxis.
Clinical observation is tested:
1. physical data: whole 160 examples are my institute's department of pediatrics Hospitalized Children in JIUYUE, 2013 in May ,-2014, and Chinese medical discrimination belongs to deficiency of spleen-YANG and kidneyYANG.Wherein man 92 example, female 68 example; Age < 12 months 56 examples, 12-24 month 54 examples, 24-36 month 50 examples; Light-duty diarrhoea 36 example, medium-sized diarrhoea 75 example, heavy diarrhoea 49 example; The course of disease 6 ~ 3 months.Be divided into treatment group and matched group at random, 2 groups of physical data comparing difference not statistically significants (P > 0.05), have comparability.
2. diagnostic criteria: with reference to the diagnostic criteria of children's's yang deficiency of spleen and stomache diarrhoea in " 22 specialties, 95 sick kind tcm clinical practice diagnosis and treatment schemes ".
3. include exclusion standard in: meet the diagnostic criteria of doctor trained in Western medicine Children's diarrhea vein (Fang Hesong. Children's diarrhea vein [M]. Beijing: People's Health Publisher, 2009.480-487.); Meet Syndrome Differentiation of Traditional Chinese Medicine; Parents of hospitalized children can support tcm therapy, and compliance is good, and can adhere to therapist; Curer is willing to after parents of hospitalized children informed consent; Get rid of and this research is held the suspicious attitude or this researcher of involuntary participation, or be associated with serious cardiovascular and cerebrovascular disease, immunodeficiency, moderate or more dehydration, mental disorder or hepatic and renal function injure and malignant tumor person, or accepting other similar therapists, or concurrent infection disease patient.
4. Therapeutic Method: all patients give oral or vein fluid infusion according to different degree of dehydration, correct dehydration and electrolyte disturbance; To heating, vomiting or the infant with other infection, give anti symptom treatment; Matched group applies DINGHUIER QITIE on this basis, once a day; The Chinese powder medicine of the treatment group application embodiment of the present invention 1 preparation, once a day; Period subtracts food according to infant situation, gives low fat, light diet; A course for the treatment of of 2 groups of equal 3d.
5. criterion of therapeutical effect: formulate with reference to " 22 specialties 95 are sick plants tcm clinical practice diagnosis and treatment schemes ", cure: stool every day 1 ~ 2 time, without Nausea and vomiting, take off water and rock-soil coupling, stool, color recover normal completely; Take a turn for the better: times of defecation obviously reduces, stool takes a turn for the better, and Nausea and vomiting, de-water and rock-soil coupling obviously improve; Do not heal: symptom and medical time without obvious change.
6. statistical analysis: adopt SPSS17.0 statistical software to carry out statistical analysis, measurement data adopts t inspection, with mean ± standard deviation
represent, data of equal value compares employing X
2inspection, with P < 0.05 for difference has statistical significance.
7. result
After 7.1 1 courses for the treatment of, two groups of comparitive study, treatment group cures 33 examples, and take a turn for the better 35 examples, total effective rate 85%; Matched group cures 12 examples, and take a turn for the better 25 examples, and total effective rate 46.25%, two groups of cure rates and total effective rate compare, and difference has statistical significance (P<0.05), and treatment group curative effect is obviously better than matched group.In table 1.
After the course for the treatment of of table 1, two groups of comparitive study, example (%)
After 7.2 two courses for the treatment of, two groups of comparitive study, treatment group cures 58 examples, and take a turn for the better 20 examples, total effective rate 97.5%; Matched group cures 33 examples, and take a turn for the better 29 examples, and total effective rate 77.5%, two groups of cure rates and total effective rate compare, and difference has statistical significance (P<0.05), and treatment group curative effect is obviously better than matched group.In table 2.
After two courses for the treatment of of table 2, two groups of comparitive study, example (%)
Can find that treatment group is apparently higher than matched group by the cure rate and total effective rate that contrast two of two groups of infants treatment courses for the treatment of, illustrate thus, Chinese medicine of the present invention has good clinical effectiveness at treatment infantile diarrhea, and short treating period, effective percentage is high, is worth promoting in clinical practice.
In a word: the present invention follows the theory of motherland's medical science inner disease outer treat, selected medical material, rigorous compatibility, the ingredient of utilization own or prescription compatibility flavour of a drug are mutually promoted, and refinforce each other.Fully take into account children's's feature, first-selected external treatment applying method simultaneously, not only simple but also practical, remarkably productive, for treatment infantile diarrhea opens the outer treating method based on Chinese powder medicine.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, Chinese medicine preparation of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
Embodiment 1
Prescription: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Rhizoma Zingiberis 2.5 parts, Cortex Jujubae 6 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 3 parts, Medulla Junci 5 parts.
Preparation method: stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis are pulverized the ethanol extraction secondary adding 50%, each 1.5 hours, and collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci crushing and water-adding are decocted secondary, first time 6 times of adding water as medical material weight portion, decoct 1.5 hours, second time adds water as 3 times of medical material weight portion decoct 1.5 hours, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add the sodium carboxymethyl cellulose of fine powder weight 3.0%, mix homogeneously, obtains powder of the present invention.
Embodiment 2
Prescription: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 6 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Rhizoma Zingiberis 2 parts, Cortex Jujubae 8 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 2.5 parts, Medulla Junci 6 parts.
Preparation method: stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis are pulverized the ethanol extraction secondary adding 50%, each 2.0 hours, and collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci crushing and water-adding are decocted secondary, first time 8 times of adding water as medical material weight portion, decoct 2.0 hours, second time adds water as 3 times of medical material weight portion decoct 1.0 hours, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add the sodium carboxymethyl cellulose of fine powder weight 2.5%, mix homogeneously, obtains powder of the present invention.
Embodiment 3
Prescription: stir-baked SEMEN PSORALEAE with salt solution 5 parts, Semen Myristicae 4 parts, the Rhizoma Atractylodis Macrocephalae 4 parts, Rhizoma Zingiberis 2 parts, Cortex Jujubae 5 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 7 parts, the Radix Aucklandiae 2 parts, Medulla Junci 4 parts.
Preparation method: stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis are pulverized the ethanol extraction secondary adding 50%, each 1.5 hours, and collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci crushing and water-adding are decocted secondary, first time 6 times of adding water as medical material weight portion, decoct 1.5 hours, second time adds water as 3 times of medical material weight portion decoct 1.0 hours, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add the sodium carboxymethyl cellulose of fine powder weight 2.7%, mix homogeneously, obtains powder of the present invention.
Embodiment 4
Prescription: stir-baked SEMEN PSORALEAE with salt solution 8 parts, Semen Myristicae 7 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Rhizoma Zingiberis 3.5 parts, Cortex Jujubae 6.5 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 3.5 parts, Medulla Junci 7 parts.
Preparation method:
Stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis are pulverized the ethanol extraction secondary adding 50%, each 1.5-2.0 hour, and collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci crushing and water-adding are decocted secondary, first time 8 times of adding water as medical material weight portion, decoct 2.0 hours, second time adds water as 4 times of decoction 1.0-1.5 hour of medical material weight portion, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add the sodium carboxymethyl cellulose of fine powder weight 2.5%, mix homogeneously, obtains powder of the present invention.
Embodiment 5
Prescription: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 7 parts, the Rhizoma Atractylodis Macrocephalae 7 parts, Rhizoma Zingiberis 2.5 parts, Cortex Jujubae 8 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 10 parts, the Radix Aucklandiae 4 parts, Medulla Junci 7 parts.
Preparation method: stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis are pulverized the ethanol extraction secondary adding 50%, each 1.5-2.0 hour, and collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci crushing and water-adding are decocted secondary, first time 8 times of adding water as medical material weight portion, decoct 2.0 hours, second time adds water as 4 times of medical material weight portion decoct 1.5 hours, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add the sodium carboxymethyl cellulose of fine powder weight 2.8%, mix homogeneously, obtains described powder.
Claims (8)
1. treat a Chinese medicine preparation for children's's yang deficiency of spleen and stomache diarrhoea, it is characterized in that it is that medicinal raw material is made by stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis, Cortex Jujubae, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), the Radix Aucklandiae, Medulla Junci.
2. Chinese medicine preparation as claimed in claim 1, is characterized in that it is made up of the medicinal raw material of following preferred weight part: stir-baked SEMEN PSORALEAE with salt solution 5-9 part, Semen Myristicae 4-8 part, Rhizoma Atractylodis Macrocephalae 3-7 part, Rhizoma Zingiberis 2-4 part, Cortex Jujubae 5-8 part, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 7-10 part, Radix Aucklandiae 2-4 part, Medulla Junci 4-7 part.
3. Chinese medicine preparation as claimed in claim 2, is characterized in that it is made up of the medicinal raw material of following preferred weight part: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 5 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Rhizoma Zingiberis 2.5 parts, Cortex Jujubae 6 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 3 parts, Medulla Junci 5 parts.
4. Chinese medicine preparation as claimed in claim 2, is characterized in that it is made up of the medicinal raw material of following preferred weight part: stir-baked SEMEN PSORALEAE with salt solution 6 parts, Semen Myristicae 6 parts, the Rhizoma Atractylodis Macrocephalae 6 parts, Rhizoma Zingiberis 2 parts, Cortex Jujubae 8 parts, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae) 8 parts, the Radix Aucklandiae 2.5 parts, Medulla Junci 6 parts.
5. the Chinese medicine preparation as described in claim 1-4, it is characterized in that it is active component by stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis, Cortex Jujubae, Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), the Radix Aucklandiae, Medulla Junci or its water and/or its extractive with organic solvent or volatile oil, add pharmaceutically acceptable adjuvant or complementary composition is prepared into pharmaceutically conventional dosage form.
6. the Chinese medicine preparation as described in claim 1-5, is characterized in that described dosage form is preferably exterior-applied formulation.
7. Chinese medicine preparation as claimed in claim 6, is characterized in that described exterior-applied formulation is preferably powder.
8. the Chinese medicine preparation as described in claim 1-7, it is characterized in that the preparation method of described powder comprises the steps: stir-baked SEMEN PSORALEAE with salt solution, Semen Myristicae, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis to add the ethanol extraction secondary of 50%, each 1.5-2.0 hour, collect merge extractive liquid, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Herba Bidentis Bipinnate (Herba Bidentis Pilosae, Herba Bidentis Pilosae), Medulla Junci are decocted with water secondary, first time add water into medical material weight portion 5-8 doubly, decoct 1.5-2.0 hour, second time adds water as the 3-4 of medical material weight portion doubly decocts 1.0-1.5 hour, collecting decoction, concentrating under reduced pressure becomes dry extract, is ground into 80-100 order fine powder for subsequent use; Get Radix Aucklandiae drying, pulverizing, cross 100 mesh sieves for subsequent use; Get Cortex Jujubae parching to brown, pulverize, cross 100 mesh sieves for subsequent use; In above-mentioned gained fine powder, add appropriate sodium carboxymethyl cellulose, mix homogeneously, obtain described powder.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1596935A (en) * | 2004-07-28 | 2005-03-23 | 马卫猛 | Medicine for treating baby and child diarrhea and its preparation method |
| CN1876171A (en) * | 2006-04-20 | 2006-12-13 | 林莲球 | Soup formulation medicine for treating kidney deficiency type chronic alvine flux and preparation method thereof |
| CN101041046A (en) * | 2007-04-19 | 2007-09-26 | 于振鹏 | Chinese traditional medicine compound took orally for treating morning diarrhea |
| CN103520681A (en) * | 2013-10-18 | 2014-01-22 | 河南中医学院 | Traditional Chinese medicine for treating spleen-and-kidney deficiency type chronic colitis |
-
2015
- 2015-07-04 CN CN201510385951.XA patent/CN105031570A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1596935A (en) * | 2004-07-28 | 2005-03-23 | 马卫猛 | Medicine for treating baby and child diarrhea and its preparation method |
| CN1876171A (en) * | 2006-04-20 | 2006-12-13 | 林莲球 | Soup formulation medicine for treating kidney deficiency type chronic alvine flux and preparation method thereof |
| CN101041046A (en) * | 2007-04-19 | 2007-09-26 | 于振鹏 | Chinese traditional medicine compound took orally for treating morning diarrhea |
| CN103520681A (en) * | 2013-10-18 | 2014-01-22 | 河南中医学院 | Traditional Chinese medicine for treating spleen-and-kidney deficiency type chronic colitis |
Non-Patent Citations (2)
| Title |
|---|
| 潘新等: "补骨脂、肉豆蔻炮制前后在"二神丸"中对脾肾阳虚泄泻小鼠的止泻研究", 《中成药》 * |
| 石海: "止泻散敷脐治疗慢性泄泻", 《实用中医内科杂志》 * |
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Application publication date: 20151111 |